• Journal of the East Asian Society of Dietary Life
• /
• v.22 no.2
• /
• pp.224-230
• /
• 2012

To investigate the effect of Panax ginseng C.A. Meyer extract (Ginseol K-b1), on skin functionality, we evaluated skin appearance and properties, such as wrinkle formation, skin moisture content, and skin elasticity in the skin of hairless mice damaged by UV irradiation. In addition, the effect of Ginseol K-b1 on collagen synthesis in human dermal fibroblasts was investigated. Female hairless mice were orally administered Ginseol K-b1 for 10 weeks with UV irradiation. Wrinkle formation in the Ginseol K-b1-treated group was significantly suppressed compared to the UV-irradiated group. Skin properties, including skin moisture content and elasticity, of the Ginseol K-b1-treated group were better than those of the control group. In the human fibroblast cells, Ginseol K-b1 treatment enhanced cell proliferation and significantly stimulated collagen synthesis. These results suggest that Ginseol K-b1 is a potent ingredient with anti-aging effects.

• The Transactions of the Korean Institute of Power Electronics
• /
• v.4 no.5
• /
• pp.442-448
• /
• 1999

We introduce the systematization design method using similarity theory which is profitable in the c compatability and standardization of the developed products and the reduction of construction time and price to d develop and design a machine equipment. Systematization design method is to select the standard model for d designing and developing from the large machinery to the super precision one and then to induce the c characteristic of machines step by step in advance in case of miniaturizing and making largelongleftarrowscale. With this m method, we extract the peculiar characteristics through the close analysis on the physical and ttx:hnical part a and predict the characteristic experiment for the magnitude we desire by an머ogical mathematical analysis. At l last, we will get the design sample the users demand with the verification of the data on optimum design p previously. In this paper, we could predict the characteristic of the product the users rC'Quire in advance with the d design method applying similarity theor${\gamma}$ and suggested the design method which could meet the various r requirements the users want. Also, it is shown that the standardization design by the similarity theory is a available as comparing the characteristic values expc'Cted through the experiment of the actual actuator with t the theoretical character data of similarity theoη after selecting the linear actuator as a model.

• Electrical & Electronic Materials
• /
• v.3 no.1
• /
• pp.9-19
• /
• 1990

본 연구에서는 산회물 혼합법, 솔-젤법, 공침법등의 세가지 방법으로 PbTiO$_{3}$분말을 제조하여 폴리머와 혼합 O-3 복합재료를 제작한 후, 하이드로폰으로의 응용을 위한 제 특성을 고찰하였다. 비유전상수는 PbTiO$_{3}$의 체적비 증가에 따라 지수함수적으로 증가하였으며 유전손실은 선형적으로 증가하였다. 수정입방체 모델로 부터 계산된 변형계수 n은 M-O, S-G, C-P의 경우 각각 0.724, 0.585, 0.483으로 나타났다. 압전 변형계수 d$_{33}$는 PbTiO$_{3}$의 체적비, 분극전장 및 분극 시간의 증가에 따라 증가하였으며 일정시간 경과후에는 포화값을 나타내었다.다.

• Proceedings of the KIEE Conference
• /
• 1997.07a
• /
• pp.94-96
• /
• 1997

A mathematical model (hybrid arc model) for arc behaviour in an $SF_6$ puffer gas-blast circuit-breaker has been developed. It has adopted the advantages of integral method and differential method. The method has been applied to model puffer circuit breaker of Noeske et al and good agreement of critical RRRV(Ratio of Rise of Recovery Voltage) has been obtained. Axial or radial distributions of temperature, electric field and arc radius are also presented and analyzed.

• Korean Journal of Environmental Biology
• /
• v.37 no.1
• /
• pp.8-18
• /
• 2019

The objectives of this study were to analyze the influence of chemical water quality on fish guilds, pollution tolerance and the multi-metric ecological health, based on the Fish Assessment Index (FAI) in the main stream of Mangyeong River between 2009-2016. The quality of water with specific conductivity, TP, and $NH_4-N$ got worse dramatically in the down region. During the study, a total of 50 species were collected and the most dominant species was Zacco platypus. Also known as tolerant species, accounted 22.9% of the total abundances, thus indicating a trophic degradation. The downstream region (S5) had the highest number of fish external abnormalities, indicating a degradation of ecological health, based on the fish assemblages. Pearson correlation analysis indicated that relative abundance of tolerant fish species and omnivore fish species had a significant positive correlation(r>0.30, p<0.05) with values of BOD, conductivity and $NH_4-N$. Whereas, the relative abundance of the sensitive species and insectivore species had a significant negative relations (r<-0.30, p<0.001) with the parameters. The mean obtained from the multi-metric fish model, based on the FAI of all sites was 47 (n=40). This indicated a "fair condition" in the ecological health, and the downstream regions (S3-S5) were judged as "bad condition", indicating an influence of the chemical degradation on the ecological health.

• The KIPS Transactions:PartC
• /
• v.11C no.6 s.95
• /
• pp.835-842
• /
• 2004

In this paper, we have analyzed the MC-DS/CDMA system with input signal synchronized completely through adjustment of the gain in the PLL loop, by using the hybrid SC/MRC-(2/3) technique, which is said to one of the optimal diversity techniques under the multi-path fading environment, assuming that phase error is defined to the phase difference between the received signal from the multi-path and the reference signal in the PLL of the receiver. Also, assuming that the regarded radio channel model for the mobile communication is subject to the Nakagami-m fading channel, we have developed the expressions and performed the simulation under the consideration of various factor, in the MC/DS-CDMA system with the hybrid SC.MRC-(2/3) diversity method, such as the Nakagami fading index(m), $the\;number\;of\;paths\;(L_p),$ the number of hybrid SC.MRC-(2/3) $diversity\;branches\;(L,\;L_c),$ the number of users (K), the number of subcarriers (U), and the gain in the PLL loop. As a result of the simulation, it has been confirmed that the performance improvement of the system can be achieved by adjusting properly the PLL loop in order for the MC/DS-CDMA system with the hybrid SC/MRC-(2/3) diversity method to receive a fully synchronized signal. And the value of the gain in the PLL loop should exceed 7dB in order for the system to receive the signal with prefect synchronization, even though there might be a slight difference according to the values of the fading index and the spread processing gain of the subcarrier.

• Korean Journal of Ichthyology
• /
• v.18 no.3
• /
• pp.202-208
• /
• 2006

An experiment was conducted to investigate the effects of three water temperatures (15, 20 and $25^{\circ}C$) in combination with three salinities (0, 15 and 30 psu) on the oxygen consumption rate of juvenile spotted sea bass, Lateolabrax maculatus (mean body weight $5.5{\pm}0.3g$). The oxygen consumption rates of L. maculatus were measured in triplicate for 24 hours using a continuous flow-through respirometer. Water temperature resulted in significant differences in the mean oxygen consumption rate of L. maculatus (p<0.001), but salinity and combinations of salinity and water temperature did not have (p>0.05). The oxygen consumption increased with increasing water temperatures in all experimental salinity regimes (p<001). Mean oxygen consumption rates at 15, 20 and $25^{\circ}C$ ranged 328.8~342.3, 433.9~441.0 and 651.5~659.9 mg $O_2\;kg^{-1}\;h^{-1}$, respectively. $Q_{10}$ values did not vary with salinity, bud varied with water temperature. $Q_{10}$ values ranged 1.63~1.75 between 15 and $20^{\circ}C$, 2.24~2.26 between 20 and $25^{\circ}C$, and 1.92~1.98 over the full temperature range. The energy loss by metabolic cost increased with increasing water temperatures in all experimental salinity regimes (p<0.001) Mean energy loss rates at 15, 20 and $25^{\circ}C$ ranged 224.6~233.8, 296.3~301.2 and $444.9{\sim}450.7kJ\;kg^{-1}\;d^{-1}$, respectively. These data suggest that the culture of juvenile spotted sea bass is possible without energy loss by salinity difference in freshwater as well as seawater after salinity acclimation. Thus, this result has an application for culture management and bioenergetic model for growth of this species.

• The Journal of Korean Society of Virology
• /
• v.28 no.1
• /
• pp.63-69
• /
• 1998

To establish in vivo antiviral evaluation system by using murine herpesvirus intracerebral infection model, 5-6 female BALB/c mice per group aged 5 weeks were inoculated i.c. into cerebrum with different inocular HSV-1 F. Signs of clinical disease noted everyday for one month. Observed were body weight decrease, neurological signs and death caused by encephalitis. Mice discontinued body weight decrease were recovered from the disease, and keratitis was often observed during recovery. The groups inoculated with higher than 1,000 PFU showed 100% mortaltiy and $LD_{50}$ was <100 PFU/mouse. To study the effect of virus inoculum sizes on antiviral effect of acyclovir (ACV), mice inoculated with different inocula were administered i.p. with different doses of ACV immediately after infection, and twice a day for 5 days. The higher inculum size, the less protective. $ED_{50}$ of ACV was >25, >25, 18.4 and 8.0 mg/kg b.i.d. in the group infected with 1,000,000, 100,000, 10,000 and 1,000 PFU/mouse, respectively. $LD_{50}$ of ACV was 62.5 mg/kg b.i.d. Therapeutic index of ACV was <2.5, <2.5, 3.0 and 7.0 in the groups with inocula 1,000,000, 100,000, 10,000 and 1,000 PFU/mouse, respectively. Inoculum size 1,000 PFU/mouse showing 100% mortaltiy and 5-6 days mean time to death, 5 days drug administration and 14 days observation will be future experimental conditions.

• Journal of fish pathology
• /
• v.14 no.1
• /
• pp.31-36
• /
• 2001

A novel clonidine binding sites were characterized in the intestinal membrane isolated from seawater eels, Anguilla japonica. The specific clonidine binding sites consisted of at least two classes, high affinity ($K_d=1.4{\pm}0.3$ nM n = 5) and low affinity ($K_d=175{\pm}34$ nM n = 5) sites. The specific binding of 2 nM [$^3H$]clonidine was most enhanced at $20^{\circ}C$ and pH 7.5, and reversed by unlabelled clonidine. Such binding was hardly inhibited by adrenaline, yohimbine or rauwolscine, indicating that most binding sites are distinct from $\alpha_2$-adrenoceptor. The specific clonidine binding sites was inhibited by various imidazoline/guanidinium drugs, indicating existence of imidazoline/guanidinium receptive sites (IGRS) or imidazoline receptors in the eel intestine. Competition experiments revealed that rank order to displace 2 nM [$^3H$]clonidine from their binding sites was as follows : guanabenz > cirazoline = naphazoline = UK14,304 = ST587 $\geq$ clonidine $\geq$ idazoxan = RX821002 = tolazoline > ST93 = oxymetazoline = amiloride = ST91 > yohimbine = efaroxan = rauwolscine $\geq$ adrenaline = ST567 = histamine = agmatine. Although physiological role of IGRS is not clear yet even in mammalian cell/tissues, eel intestine may be a good model to elucidate how the IGRS act in the cell and to decide what is the endogenous ligand for the IGRS.

• Journal of Korean Society of Environmental Engineers
• /
• v.22 no.1
• /
• pp.121-132
• /
• 2000

This study is to investigate the performance of a new BNR process using predenitrification scheme focusing on nitrogen removal and the possibility of adapting a computer simulation scheme in BNR process development. By using a pre-denitrification basin, higher $COD/NO_3-N$ ratio could be sustained in this BNR process. The results of the investigation showed a SDNR value of 9.04mg/gMv/hr. In the anoxic tank, the average value of SPRR of 6.25mgP/gMv/hr was observed to be very sensitive to SCOD load of influents. By calibrating internal parameters (stoichiometric and kinetic parameters) of the simulation model, the results of simulation for various BNR processes gave good agreement with observed data. The major adjustment was given with three parameters, maximum specific growth rate of heterotrophic biomass, short chain fatty acid (SCFA) limit, and phosphorous release rate. With the series of simulations on varying operational conditions, the simulation by computer program can be a useful tool for process selection, and design and operation of municipal wastewater treatment plant.