• Title/Summary/Keyword: P limitation

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아질산성 질소의 축적에 대한 용존 산소와 free ammonia의 영향 연구

  • Han, Dong-U;Lee, Su-Cheol;Lee, Nam-Hui;Kim, Dong-Jin
    • 한국생물공학회:학술대회논문집
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    • 2000.11a
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    • pp.475-478
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    • 2000
  • For an integrated nitrification-denitrification process, nitrite formation in the aerobic stage leads to big savings. Dissolved oxygen concentration, temperature, pH and free ammonia concentration have been meet for nitrite accumulation. Also their effects over the ammonia oxidizers and nitrite oxidizers have been studied. Dissolved oxygen limitation and free ammonia inhibition led to slow nitrification and nitrite build up. In this study batch kinetics of ammonium and nitrite oxidations were performed with free ammonia accumulated nitrifiers. From the results it is likely the nitrite oxidizers are inhibited by oxygen limitation rather than free ammonia.

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Nitrogen Control in Corynebacterium glutamicum: Proteins, Mechanisms, Signals

  • Burkovski, Burkovski;Andreas, Andreas
    • Journal of Microbiology and Biotechnology
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    • v.17 no.2
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    • pp.187-194
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    • 2007
  • In order to utilize different nitrogen sources and to survive in a situation of nitrogen limitation, microorganisms have developed sophisticated mechanisms to adapt their metabolism to a changing nitrogen supply. In this communication, the recent knowledge of nitrogen regulation in the amino acid producer Corynebacterium glutamicum is summarized. The core adaptations of C. glutamicum to nitrogen limitation on the level of transcription are controlled by the global regulator AmtR. Further components of the signal pathway are GlnK, a $P_{II}-type$ signal transduction protein, and GlnD. Mechanisms involved in nitrogen control in C. glutamicum regulating gene expression and protein activity are repression of transcription, protein-complex formation, protein modification by adenylylation, change of intracellular localization, and proteolysis.

Effectiveness of Upper Extremity Exercise and Bandage on the Edema and ROM of Patients with Lymphedema (상지운동과 붕대법이 상지림프부종 환자의 부종과 관절가동범위에 미치는 영향)

  • Lim, Chang-Hun;Han, Jin-Tae
    • Journal of the Korean Society of Physical Medicine
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    • v.6 no.1
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    • pp.31-38
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    • 2011
  • Purpose : The purpose of this study was to examine the effect of upper extremity exercise and Bandage on the edema and range of motion. Complex decongestive physiotherapy was one of the latest methods to deal with the limitation of range of motion and the edema that were the prime problems of patients with lymphedema. Methods : Twenty patients undergone mastectomy were participated in this study voluntarily. They had lymphedema on upper extremity and partial limitation of range of motion. The subjects had been treated with upper extremity home exercise and complex decongestive physiotherapy with Bandage for 4 weeks. The measure of these patients with upper extremity edema was included: the volume, arm circumfenence and range of motion. These were measured two times: before the treatment, after 4 weeks of the treatment. Results : The upper extremity edema of patients treated home exercise group and complex decongestive physiotherapy group with Bandage was definitely decreased (p<0.05). Moreover, the upper volume of those who were the same condition also significantly shrank and patients' arm circumferences of upper arm breathtakingly diminished as well (p<0.05). But home exercise group patients' arm circumferences of forearm was not remarkable(p>0.05). However, patients' range of motion who were treated with upper extremity exercise were evidently increased when compared to that of the before treatment (p<0.05). Conclusion : Complex decongestive physiotherapy and bandage performed by physical therapist increased the ROM of upper arm and reduced the edema in patients with lymphedema.

A Study on the Attitude of University Students on Understanding Disabed (대학생의 장애 이해에 대한 태도 연구)

  • Kim, Young-Hee
    • Journal of Korean Physical Therapy Science
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    • v.9 no.1
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    • pp.95-102
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    • 2002
  • The present study focuses on the relation of the attitudes of university students to disabled by using modified disability factor scales(DFS, Siller). As for the attitude areas, it relies on the eight categories DFS provides. The 8 categories that specify each attitude area are: generalized rejection, distressed identification, inferred emotional consequences, imputed functional limitation, authoritarian virtuousness, rejection of intimacy, interaction strain, mainstreaming. This study is based on a series of questionnaire researches conducted on 322 students, over the period from October 19th to November 14th, 2001. The questionnaire carries 50 items, covering the 8 attitude areas and each item has 5 choices. The subjects' responses to each of the areas are examined in their relations to the four conditions, as they are analysed by t-test and one way ANOVA. The conclusion drawn from the research are as follows: 1. There is no significant difference between the students of the department concerned with the problem of disability, and those of the department unconcerned. But the responses are significantly different in the three areas of generalized rejection, rejection of intimacy and interaction strain(1st condition, P<.05). 2. The responses are significantly different in 6 areas except for the two, distressed identification and inferred emotional consequences, between the students who have volunteered services as helpers of the disabled and those who have no such experiences(2nd condition, P<.05). 3. the responses are significantly different between those who have volunteered long-time services and those who are far less experienced(3nd condition, P<.05). 4. There is no significant difference, whether the subjects have disabled persons around them or not. But generalized rejection, authoritarian virtuousness, rejection of intimacy, interaction strain & mainstreming show significant differences(4th condition, P<.05). 5. Generalized rejection, rejection intimacy and interaction strain show significant differences in every pair of the 4 condition. 6. Distressed identification and inferred emotional consequence show no significant difference between the two conditions in every pair of the 4 considerations.

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Adjusting Local Network Speed by Using Fuzzy Theory with An Illustration in WebRTC Environment (퍼지이론과 예증을 이용한 WebRTC환경의 로컬 네트워크 속도 조정)

  • Van, Linh Ma;Jang, Jong-hyun;Kim, Jinsul
    • Journal of Digital Contents Society
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    • v.16 no.6
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    • pp.917-925
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    • 2015
  • WebRTC is one of the most recent technologies that supports browser-to-browser for voice calling, video chat, and P2P file sharing without the need of either internal or external plugins. However, there has some limitation which lets our development deal with many problems. This research will focus just on a small field of that problem which is bandwidth. While the bandwidth for downloading and uploading is fixed by service providers, but the number of users in a certain area is increasing largely by the time. In this paper, we propose a model to overcome the limitation of the bandwidth based on fuzzy control to adjust utilized bandwidth by changing frame rate and resolution of streaming video in the client itself.

A Proposal of the Maximum Allowable Off-axis e.i.r.p. Level of HAPS Ground Station for Frequency Sharing with 47/48GHz FSS system (47/48GHz FSS 위성 시스템과의 주파수 공유를 위한 HAPS 지상국의 최대 허용 off-axis e.i.r.p. 레벨 제안)

  • Kang, Young-Heung;Choi, Mun-Hwan
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.11 no.3
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    • pp.459-464
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    • 2007
  • Resolution 122 requires to study power limitation applicable for HAPS ground stations to facilitate sharing with space station receivers in 47/48GHz bands. ITU-R Recommendation 1481-1 recommends to improve the side lobe characteristics of HAPS ground station antenna for frequency sharing between FSS system and HAPS system. In this paper, we propose the maximum allowable off-axis e.i.r.p. level of HAPS ground station antennas by considering power limitation to HAPS ground station in Resolution 122, and by improving the side lobe characteristics of HAPS ground station antennas in Recommendation SF.1481-1. The simulation results show that the unfeasible sharing distance between HAPS ground station and FSS earth station can be reduced remarkably, and give the possibility of frequency sharing between two above systems.

Binding Subsites In the Active Site of $Zn^{2+}$-Glycerophosphocholine Cholinephosphodiesterase

  • Sok, Dai-Eun;Kim, Mee-Ree
    • BMB Reports
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    • v.28 no.2
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    • pp.94-99
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    • 1995
  • The properties of binding sites in the active site of $Zn^{2+}$-glycerophosphocholine cholinephosphodiesterase were examined using substrates and inhibitors of the enzyme. Phosphodiesterase hydrolyzed p-nitrophenylphosphocholine, p-aminophenylphosphocholine, and glycerophosphocholine, but did not hydrolyze either acylated glycerophosphocholine or bis (p-nitrophenyl)phosphate, suggesting a size limitation for interaction with a glyceryl moiety-binding subsite. The hydrolysis of p-nitrophenylphosphocholine was competitively inhibited by glycerophosphocholine and p-aminophenylphosphocholine, while glycerophosphoethanolamine was a weak inhibitor. The enzyme was also inhibited by choline, but not by ethanolamine. Thiocholine, a much more potent inhibitor than choline, was more inhibitory than cysteamine, suggesting a strict specificity of an anionic subsite adjacent to a $Zn^{2+}$ subsite. Of all oxyanions tested, the tellurite ion was found to strongly inhibit the enzyme by binding to a $Zn^{2+}$ subsite. The inhibitory role of tellurite was synergistically enhanced by tetraalkylammonium salts, but not by glycerol. Deactivation of the enzyme by diethylpyrocarbonate was partially protected by choline, but not by glycerophosphate. It is suggested that the active site of phosphodiesterase contains three binding subsites.

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Comparative Modeling of Human P-gp NBD2 and Docking and Binding Mode Analysis of 8-Geranyl Chrysin as a P-gp Modulator

  • Gadhe, Changdev G.
    • Journal of Integrative Natural Science
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    • v.5 no.1
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    • pp.18-21
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    • 2012
  • The resistance of tumour cells against cytotoxic drug is significant limitation in successful chemotherapeutic treatment of cancer. To date, no crystal structure is available for human P-gp. We developed homology model for human P-gp NBD2 by using coordinates of transporter associated protein (TAP1). Docking study was performed for 8-geranyl-chrysin (Flavonoids) inhibitor in the NBD2 model. Ligand-protein interactions were determined which indicates that the 8-geranyl chrysin shares two overlapping sites in the cytosolic domains of P-gp, the ATP site and a hydrophobic steroid-binding site.

Temporal Changes of Limiting Nutrients and Phytoplankton Growth Rate in Lake Paldang (팔당호 식물플랑크톤의 제한영양염과 성장률의 경시적 변화)

  • Choi, Kwang-Hyun;Kim, Ho-Sub;Han, Myung-Soo;Hwang, Soon-Jin
    • Korean Journal of Ecology and Environment
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    • v.36 no.2 s.103
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    • pp.139-149
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    • 2003
  • This study was conducted to determine limiting nutrients and the physiological characteristics of phytoplankton in response of nutrients in Lake Paldang from March 2002 to October 2002. A field research was conducted along with laboratory batch culture experiment to find the limiting nutrients and the growth kinetics. According the results of Chl. a TP relationship, TN/TP ratio, and nutrient addition bioassay, phosphorus appeared to be a major limiting nutrient in Lake Paldang and thus the lake productivity was greatly influenced by it. P limitation for the phytoplankton of Lake Paldang varied with season, and the possibility of limitation by nitrogen and silica also occurred. The degree of P limitation was greatest during spring when the concentration of dissolved phosphorus is relatively much lower than summer and autumn. The maximum growth rate (${\mu}_{max}$) and half saturation concentration ($K_u$) of Lake Paldang phytoplankton ranged from 0.8${\sim}$1.1$day^1$ and from 0.1${\sim}$O.8${\mu}M$, respectively. $K_u$ was highest during May ($0.8{\mu}M$) and the lowest during September ($0.1{\mu}M$). Such result may be induced by the phytoplankton cell quota that showed the lowest concentration ($0.13{\mu}gP/{\mu}gChl.$ a) during May. The growth kinetics showed that phytoplankton growth in Lake Paldang was faster during summer and autumn than spring, suggesting that the Potential of algal bloom is high after the summer monsoon season.

Short-term Effect of Botulinum Toxin Injection on the Surface EMG of Masticatory Muscles and Jaw Function (교근 부위의 보툴리눔 독소 주사가 저작근의 근전도 및 악기능에 미치는 영향)

  • Lee, Jeong-Yun;Park, Hee-Kyung;Chung, Jin-Woo
    • Journal of Oral Medicine and Pain
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    • v.31 no.1
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    • pp.69-77
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    • 2006
  • Botulinum toxin injection has been used in the masticatory muscle area as an effective treatment method of various movement disorders and facial contouring, but its effects on jaw function have not been evaluated. The aims of this study were to evaluate the effects of botulinum toxin type A injection into the masseter muscle on the EMG activities of masseter and anterior temporal muscles, and the limitation of jaw function. Fourteen healthy subjects were recruited. Five subjects were injected with 80 units of botulinum toxin type A(Dysport, Ipsen, Wrexham, UK) into each side of masseter muscle, and nine subjects were injected with saline into the same site as the botulinum toxin group. The surface EMG activities at maximum voluntary contraction of masseter and anterior temporal muscles were recorded before, 1 week, 2 weeks, and 3 weeks after injection. Presence of jaw functional limitations in each subject was investigated using Korean version of Jaw Functional Limitation Scale(JFLS) questionnaire. The masseter muscle EMG was gradually decreased in the botulinum toxin group comparing with that of the control group(p<0.001), but the anterior temporal muscle EMG did not show significant changes. There was significant increases in the mastication (p<0.01), and global jaw limitation(p<0.05) subscales of JFLS at 1 week after injection, but no significant changes in the other subscales including opening, and verbal and emotional expression during the recording periods. Our results suggest that botulinum toxin injection into masseter muscle can affect modest limitation in mastication function at 1 week after injection but recovered to the baseline until 3 weeks after injection. The EMG activity of masseter muscle had been gradually decreased until 3 weeks after botulinum toxin injection but the anterior temporal muscle did not show any significant changes.