• Title/Summary/Keyword: P·I Control

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Clinical study on face temperature of infertility women with severe anovulation or oligo-ovulation or hypothalamic-pituitary gland hormone disorders (중증 배란장애 및 뇌하수체분비호르몬 이상을 보이는 불임 환자의 안면체열분포에 관한 임상적 고찰)

  • Cho, Hyun-Ju;Lim, Jung-Han;Choi, Eun-Mi;Kang, Myung-Ja
    • Journal of Oriental Medical Thermology
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    • v.2 no.1
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    • pp.35-42
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    • 2003
  • Objective : This study is to examine the interrelationship between Infertility with hypothalamic-pituitary gland disorders and Face temperature by D.I.T.I. Methods : Sample group is the 50 women who were diagnosed as P.C.O.S. or FSH,LH trouble or hyper-prolactinemia or anovulation or oligo-ovulation. Control group is the 50 women who have not P.C.O.S. & FSH.LH trouble & hyper-prolactinemia & anovulation or oligo-ovulation, who have normal menstural cycle and success in pregnancy after treatment. Both group came at Conmaul Oriental Hospital Infertility Center, Seoul, Korea, from May, 2001 to Jan., 2003. They selected at random. We checked temperature of ${\ulcorner}S17{\lrcorner}\;{\ulcorner}SI18{\lrcorner}\;{\ulcorner}TE17{\lrcorner}\;{\ulcorner}HN-3{\lrcorner}$ and gained differences of Rt. check point and Lt. check point, and then compared mean ${\Delta}T$ of sample group with that of control group. Conclusion : We gained results that mean ${\Delta}T$ of sample group is larger than that of control group at all check points. (p=0.000)

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A Psychological Study on the MPDS Patients (인성검사를 이용한 MPDS환자의 심리적 분석)

  • 김정호
    • Journal of Oral Medicine and Pain
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    • v.8 no.1
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    • pp.97-106
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    • 1983
  • A reserch scale of 48 items selected from MMPI by McCall et al. was used to compare psychologic aspects of 80 patients with MPDS to control I subjects and control II subjects. For this, study subjects were selected 80 patients of MPDS who visited the Dept. of Dentistry. K.N.U.H., from December in 1982 to September in 1983. Control I subjects were selected 80 outpatients without MPDS who required dental treatment from December in 1982 to September in 1983. And control II subjects were selected 80 persons without MPDS who required no dental treatment and lived in Taegu. The results were as follow : In study subjects,somatic gruop and behavioral group are markedly high than control (I,II)subjects. In somatic group and behavioral group, there was no significant differencd between control I subjects and control II subjects. In somatics group and begavioral group, there was no significant difference between male and female in each subjects: In study subject, general nature somatic category was higher than head, neck, throat and GIT somatic category.(P<0.05) In study subjects, somatic group and behavioral group gradually increased according to increase in number of MPDS symptom.

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A STUDY ON THE TENSILE BOND STRENGTH OF COMPOSITE RESIN INLAYS ACCORDING TO THEIR INTERNAL SURFACE TREATMENT AND TYPES OF LUTING CEMENT (복합레진 인레이의 내면처리와 합착용 시멘트의 종류에 따른 인장접합강도에 관한 연구)

  • Kim, Jin-Cheol;Cho, Young-Gon;Hwang, Ho-Keel
    • Restorative Dentistry and Endodontics
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    • v.18 no.1
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    • pp.103-113
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    • 1993
  • The purpose of this study was to evaluate the tensile bond strength of composite resin inlays according to the their internal surface treatment and types of luting cement and compared them with the conventional direct resin filling thchnique. Class II cavities were prepared in 50 extracted human molar teeth, and then equally divided into five groups. Group 1 : Cavities of control group were directly filled with P-50. Group 2 : Cavities of resin inlay group were luted with resin cement. Group 3 : Cavities of resin inlay group were luted with luting G-I cement. Group 4 : Cavities of resin inlay group were luted with resin cement after sandblasting. Group 5 : Cavities of resin inlay group were luted with luting G-I cement after sandblasting. All specimens were polished with same method and stored in normal saline for 24 hours before testing. An Universal Testing machine(Model No. AGS-100A, Shimadzu, Japan) was used to apply tensile loads in the vertical direction, and the force required for separation was recorded with a cross-head speed of 5mm/min and 100kg in full scale. The results were as follows : 1. The mean tensile bond strength was lowest in group luted with luting G-I cement, with measurements of $14.45{\pm}0.78(kg/cm^2)$ and highest in group luted with resin cement after sandblasting, with measurements of $49.6{\pm}2.74(kg/cm^2)$. 2. The tensile bond strength was greater in resin inlay groups luted with resin cement than in control group and resin inlay groups luted with luting G-I cement(P<0.05). 3. The tensile bond strength was lower in resin inlay groups luted with luting G-I cement than in control group(P<0.05). 4. The tensile bond strength was greater in resin inlay groups luted with resin cement or luting G-I cement after sandblasting than without that(P<0.05).

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A Study on the Upset Prevention & Recovery Training Method for Navy Fixed Wing Pilots Using P-3 Simulator (P-3C 시뮬레이터를 활용한 해군 고정익조종사 UPRT 훈련 방안에 대한 연구)

  • Jung-bong Lee
    • Journal of Advanced Navigation Technology
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    • v.27 no.3
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    • pp.293-299
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    • 2023
  • UPRT(Upset Prevention And Recovery Training) is an accident prevention training program developed over a three-year period after the main cause of aircraft accidents in commercial aviation between 2001 and 2011 was analyzed as LOC-I(Loss Of Control Flight). In 2014, ICAO presented UPRT for fixed-wing aircraft through Doc.10011(Manual On Aeroplane Upset Prevention And Recovery Training) and recommended mandatory implementation to Contracting States from March 2019. Since naval P-3C is a major mission of maritime patrol and anti-submarine warfare, it takes a lot of time to fly at low altitude (70-600 m), and the majority of P-3C pilots have experienced spatial disorientation, so Upset prevention and recovery training is essential for naval P-3C pilots. To this end, this study intends to present measures for UPRT from limited conditions using the P-3C simulator owned by the Navy.

Role of cAMP, EGF, IGF-I and Protein Phosphorylation in Mammary Development I. Effect of EGF, IGF-I and Photoreactive Cyclic AMP on DNA Synthesis of Mammary Epithelial Cell (유선발달에 있어서 cAMP, EGF, IGF-I 및 단백질 인산화 작용의 역할 I. EGF, IGF-I 및 Photoreactive Cyclic AMP가 유선상피세포의 DNA합성에 미치는 효과)

  • 여인서;박춘근;홍병주
    • Korean Journal of Animal Reproduction
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    • v.17 no.1
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    • pp.49-56
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    • 1993
  • Mouse mammary epithelial cells(NMuMG) were plated onto 24 well phates(100,000 cells/well), in DMEM supplemented with 10% fetal calf serum. After serum starvation for 24 hours, EGF)0~100ng/ml) was added simultaneously with IGF-I(10ng/ml), 1$\mu$M photoreactive cAMP(4,5-dimethoxy-2-nitrobenzyl adenosine-3',5' cyclic monophosphate, DMNB) or IGF-I plus DMNB. After 2 hours, the cells were expposed to UV light(300nm, 3 second pulse0 in order to activate DMNB which induces a rapid transient increase in intracellular cAMP upon UV irradiation. DNA synthesis was estimated as incorporation of 3H-thymidine into DNA(1 hour pulse with 1$\mu$Ci/ml, 18~19 hours after UV exposure). Without IGF-I or DMNB, EGF(10 or 100ng/ml) increased DNA synthesis from 8,362 dpm/well in control to 16,345 or 18,684 dpm/well with EGF(pooled SE=1,239 dpm/well, P<0.05). IGF-I or IGF-I plus DMNB alone increased DNA synthesis from 8,362 dpm/well in control to 17,307 or 20,427 dpm/well, respectively(P<0.05). Addition of IGF-I, DMNB or IGF-I plus DMNB into 0~100ng/ml EGF did not significantly change the shape of dose response curve of EGF alone. In other experiment, EGF or IGF-I plus DMNB into 10ng/ml EGF group exhibited interaction effect in DNAsynthesis [EGF(10ng/ml)=18,497; IGF-I+EGF=22,837; DMNB+EGF=20,658 ; IGF-I+DMNB+EGF=29,658, pooled SE=1,055, P<0.05]. These results indicate that simultaneous activation of EGF, IGF-I and intracellular cAMP interact in DNA synthesis of mouse mammary epithelial cells.

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Role of cAMP, EGF, IGF-I and Protein Phosphorylation in Mammary Development II. Interaction Effects of EGF, IGF-I and Photoreactive Cyclic AMP on DNA Synthesis and Protein Phosphorylation (유선발달에 있어서 cAMP, EGF, IGF-I 및 단백질 인산화 작용의 역할 II. EGF, IGF-I 및 Photoreactive Cyclic AMP의 상호작용과 단백질 인산화 작용)

  • 여인서
    • Korean Journal of Animal Reproduction
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    • v.19 no.2
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    • pp.95-104
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    • 1995
  • Mouse mammary epithelial cells(NMuMG) were maintained onto 6-well plates (3$\times$105 cells/well) or chambered slide (1$\times$104 cells/well), in DMEM supplemented with 10% fetal calf serum. After serum starvation for 24 hours, DMNB (1$\mu$M) was added and exposed to UV light (300nm, 3 second pulse) after 2 hours from DMNB addition in order to activate DMNB which induces a rapid transient increase in intracellular cAMP upon UV irradiation. EGF (100ng/ml) and/or IGF-I (10ng/ml) were treated at the time of UV irradiation. Nuclear labeling index was estimated as percent of nuclear labeled cells(percent of S phase of cells) by incorporation of 3H-thymidine into DNA(1 hour pulse with 1$\mu$Ci/ml). DMNB(1$\mu$M), EGF (100ng/ml) and/or IGF-I (10ng/ml) signifciantly increased nuclear labeling index than those of control (P<0.05). Addition of DMNB+EGF or DMNB+EGF+IGF-I showed the interaction effect in nuclear labeling index (P<0.05). Protein kinase A activities by addition of EGF, IGF-I or EGF+IGF-I were 10.5, 9.8 or 9.4 unit/mg protein, respectively, and no statistical difference was found in comparison with control (P>0.05). Additon of DMNB+EGF showed the moderate interaction effect on tyrosyl kinase activity (P<0.1). In the fluorography analysis, there were no specific protein phosphorylation patterns were found at 1 or 15 minute by addition of DMNB. EGF and/or IGF-I. These results suggest that the interaction effect in nuclear labeling index by addition DMNB and EGF could be mediated through the modulation of tyrosyl kinase activity by cAMP.

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Association of ionized magnesium, total magnesium, gestational age, and intraventricular hemorrhage in preterm babies (미숙아에서 이온화 마그네슘, 총 마그네슘과 재태 연령과의 관계 및 뇌실 내 출혈과의 관계)

  • Kim, Tae-Yeon;Lee, Hyun-Hee;Sung, Tae-Jung
    • Clinical and Experimental Pediatrics
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    • v.52 no.10
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    • pp.1140-1146
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    • 2009
  • Purpose:The pathophysiology of magnesium, the second highest common compound in humans, is still unclear, especially in preterm babies. We accessed the association between total magnesium (tMg), ionized Mg (iMg), and gestational age (GA) and that between serum magnesium (sMg) and intraventricular hemorrhage (IVH) in preterm babies. Methods:In all, 119 inborn preterm infants admitted between July 2006 and February 2008 were divided into the IVH group (19) and the control group (100) and were prospectively analyzed. TMg, iMg, pH, total calcium (tCa), and ionized Ca (iCa) levels were determined immediately after delivery or within 3 hours after birth, and their correlation with GA were investigated. Results:TMg was not correlated with GA, tCa, iCa, and pH. IMg was correlated with tMg (r=0.288, P=0.002) and iCa (r=0.212, P=0.021); however, it was not correlated with GA and pH. Mean GA and birth weight were significantly lower (P=0.002) and smaller (P=0.030) in the IVH group. Mean sMg was higher in the IVH group ($2.5{\pm}0.9mg/dL$) than in the control group ($2.1{\pm}0.6mg/dL$) (P=0.021). SMg was a risk factor even after logistic regression analysis (OR, 2.798; 95% C.I., 1.265-6.192; P=0.011). Conclusion:In less than 37-week-old preterm babies, tMg and iMg were similar, regardless of GA. High sMg may be a risk factor for IVH in premature babies, regardless of their exposure to antenatal magnesium.

Evaluation of Thin-Film Photodevices and Development of Artificial Retina

  • Kimura, Mutsumi;Shima, Takehiro;Yamashita, Takehiko;Nishizaki, Yoshitaka;Hara, Hiroyuki
    • 한국정보디스플레이학회:학술대회논문집
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    • 2007.08b
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    • pp.1745-1748
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    • 2007
  • First, thin-film photodevices are evaluated, and a p/i/n thin-film phototransistor (TFPT) is recommended because the photo-induced current is relatively high and independent of the applied voltage. Next, an artificial retina is developed using the p/i/n TFPTs, and it is found that it can detect photo illuminance profile with sensitivity control.

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CLINICAL ASSESSMENT OF THE VELOPHARYNGEAL INCOMPETENCY SPEAKERS WITH SPEECH AIDS (발음보조장치를 이용한 비인강폐쇄부전환자의 음성언어 평가)

  • Ko, Seung-O;Shin, Hyo-Keun
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.26 no.4
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    • pp.414-421
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    • 2000
  • The objective evaluation of velopharyngeal closure function is the key to diagnosis and therapy control of velopharyngeal incompetency. The aim of this study is to evaluate the aerodynamic and acoustic characteristics of the velopharyngeal closure function of patients who have developed velopharyngeal incompetency after management with speech aids. The test words were composed of sustained vowels /a/, /i/, /e/, /u/, /ja/, /je/, /wi/ and polysyllabic words /p'ap'i/, /siso/, /mami/ for measuring nasalance, The data was collected before the placement of the speech aids and one to three months after. The results were as follows: The nasalance score of the velopharyngeal incompetency speakers was higher than that of the normal control group, except for nasal sounds, and was decreased after placement of the speech aids, especially in high vowels /i/ (P<.01) and /wi/ (P<.05).

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The effect of artemisinin on the rabbit IgG accelerated nephrotoxic serum glomerulonephritis in mice (개똥쑥에서 분리(分離)된 artemisinin이 가토(家兎) IgG에 의해 유발(誘發)된 생쥐의 현독성(賢毒性) 혈청사구체현염(血淸絲球體賢炎)에 미치는 영향(影響))

  • Zhu, Quan
    • Journal of Haehwa Medicine
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    • v.4 no.2
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    • pp.335-336
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    • 1996
  • Artemisinin, a new antimalarial to treat patients infected with strains of Plasmodium jalciparum, derived from the plant Artemisia annua Linn, has immunopharmacologic actions such as enhence the PHA -induced lymphocyte transformation rate, increased the weight of spleen but reduced the weight of thymus, reduced phagocytic function of peritoneal macrophage, remarkably reduced the level of serum IgG and hemolysin fonning capacity (sentitized with SRBC), inhibited the activity of Ts cells of donor mice by supraoptimal immunuization(SOI), but enhenced activity of Ts cells of recipient mice by SOI. These results suggested that Ts cells may be the target cells of artemisinin. To the serum complement C3 level of plasmodium berghei-infeted mice, artemisinin (i. m,) could remarkly increase it. The artemisinin also obviously reduced the prostaglandin E(PGE) in the mouse hind paw swelling induced by carrageenin. Numerous studies have demonstrated that pharmacologic doses of PGE attenuate the development of immunocomplex nephritis. Some autologous immune mechanisms may be invoolved In the pathogensis of some types of glomurulonephritis. Glomerular abnormalities can be induced in animals by variety of immunological manipulations. The resulting disorder has many clinical and pathogical similarities to the disease in human. Our purpose was therefore to test the ability of the artemisinin to lessen the severity of rabbit IgG accelerated nephrotoxic serum glomerulonephritis in mice model. Mice which had treated with rabbit IgG and NTS, administrated with saline, showed Significant inceases of urinary protein, cholesterol level, and decrease of serum albumin in NS group. On the contrary, By i.g. adminstration of artemisinin at dose of 12.5, 25 and 50 mg/kg for 14 days after NTS injection, shown that artemisinin inhibited the nephritic changes in some parameters by means of urinary protein(p<0.05, p<0.01) and serum choleterol(p<0.05, p<0.01) and albumin (p<0.05, p<0.01), blood urea nitrogen (p<0.05, p<0.01), serum albumin(p<0.05, p<0.01); Cyclophosphamide(i.p. 10mg/kg for 14d) had almost same effect as the artemisinin had. Morphological studies shown that The picture of kidney from the mouse with NTS-nephritis accerated with rabbit IgG, treated with i.g. saline as the control, the mesangiocapillary were enlarged and proliferated; There were inflammatory cells infiltrating around the glomeruli; The ethelial cell were proliferated in the wall of Bowman's capsule. Histopatholological picture of kidney from the NTS-nephritis accerated with rabbit IgG mouse treated with i.p. 10mg/kg cyclophosphamide as the positive control. No siginicant histopathological evidence were found. Treaded with i.p. 12.5mg/kg artemisinine, the picture shown that mesangiocapillary were lightly proliferated; There were inflammatory cells infiltrating around the glomeruli; Treaded with i.p. 25mg/kg artemisinine, The picture shown that the mesangiocapillary were lightly proliferated; Treaded with i.p. 50mg/kg artemisinine, The picture shown that both the mesangiocapillary proliferated and the inflammatory cells infiltrating around the glomeruli are less than treated with saline, 12.5 and 25 mg/kg artemisinine. On the basis of these studies we conclude that the artemisinin can relieve pathological change caused by NTS-nephritis aacerated with rabbit IgG.

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