• KSII Transactions on Internet and Information Systems (TIIS)
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• 제11권9호
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• pp.4641-4657
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• 2017

Named Data Networking (NDN) has emerged and become one of the most promising architectures for future Internet. However, like traditional IP-based networking paradigm, NDN may not evade some typical network threats such as malicious data aggregates (MDA), which may lead to bandwidth exhaustion, traffic congestion and router overload. This paper firstly analyzes the damage effect of MDA using realistic simulations in large-scale network topology, showing that it is not just theoretical, and then designs a fine-grained MDA mitigation mechanism (MDAM) based on the cooperation between routers via alert messages. Simulations results show that MDAM can significantly reduce the Pending Interest Table overload in involved routers, and bring in normal data-returning rate and data-retrieval delay.

• 전기학회논문지P
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• 제55권4호
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• pp.190-195
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• 2006

In this paper, safety algorithm of transformer is introduced for the sake of MV/LV distribution customers by using fuzzy theory. The current-carrying capacity of transformer is usually determined by the maximum temperature at which the transformer is permitted to operate. Overload of transformer has an effect on transformer utilization rate and maximum temperature rises as well as maximum ambient temperature of insulating materials. Therefore, we proposed the safety algorithm considering the overload of transformer and ambient temperature in this paper. We introduced the correlational equations between each parameters using experimental data of IEEE std C57.91-1995, and deduced the result using fuzzy reasoning. We guessed the safety algorithm making a diagnosis for the safety status of oil-immersed transformer.

• 한국컴퓨터정보학회논문지
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• 제21권1호
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• pp.147-153
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• 2016

In this paper, we propose an efficient dynamic workload balancing strategy which improves the performance of high-performance computing system. The key idea of this dynamic workload balancing strategy is to minimize execution time of each job and to maximize the system throughput by effectively using system resource such as CPU, memory. Also, this strategy dynamically allocates job by considering demanded memory size of executing job and workload status of each node. If an overload node occurs due to allocated job, the proposed scheme migrates job, executing in overload nodes, to another free nodes and reduces the waiting time and execution time of job by balancing workload of each node. Through simulation, we show that the proposed dynamic workload balancing strategy based on CPU, memory improves the performance of high-performance computing system compared to previous strategies.

• Asia pacific journal of information systems
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• 제30권1호
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• pp.120-142
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• 2020

Present-day organizations have become largely dependent on mobile instant messaging services (MIMs) for various organizational purposes. Focusing on the increasing use of MIMs in today's organizations, this study aims to explain how different aspects of KakaoTalk, the most dominant MIM in Korea, influence employees' attitudes toward their current employers, and how these attitudes impact the employees' intentions to stay at their present workplaces. Overall, with the exception of one factor (satisfaction with KakaoTalk use), all other factors (perceived quality of information exchanged through KakaoTalk, belongingness through KakaoTalk, and KakaoTalk overload) significantly influenced employee's attractiveness toward their current employers. Specifically, while KakaoTalk overload's effect on perceived organizational attractiveness was negative, two other factors were positively associated with it. Perceived organizational attractiveness also strongly influenced employees' intention to stay at their present workplaces. These findings contribute to expanding practical and theoretical understandings regarding the critical roles of MIMs in the efficient management of organizations in this hyperconnected society.

• Biomolecules & Therapeutics
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• 제19권4호
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• pp.445-450
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• 2011

Preciously, we demonstrated that a novel NHE-1 inhibitor, KR-33028 attenuated cortical neuronal apoptosis induced by glutamate. In the present study, we investigated the signaling mechanism of neuroprotective effect of KR-33028 against glutamate-induced neuronal apoptosis, especially focusing on mitochondrial death pathway. Our data showed that glutamate induces a biphasic rise in mitochondrial $Ca^{2+}$ and that KR-33028 significantly prevents the second phase increase, but not the first phase increase in mitochondrial $Ca^{2+}$. Furthermore, KR-33028 restored the ${\Delta}{\Psi}_m$ dissipation and cytochrome c release into cytoplasm induced by glutamate in a concentration-dependent manner. The inhibition of mitochondrial $Ca^{2+}$ overload by ruthenium red also inhibited glutamate-induced apoptotic cell death, mitochondrial membrane potential, ${\Delta}{\Psi}_m$ dissipation and cytochrome c release. These data suggest that inhibition of mitochondrial $Ca^{2+}$ overload is likely to be attributable to anti-apoptotic effect of KR-33028. Taken together, our results suggest that anti-apoptotic effects of NHE-1 inhibitor, KR-33028 may be mediated through maintenance of mitochondrial function.

• 한국정보시스템학회지:정보시스템연구
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• 제29권2호
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• pp.265-286
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• 2020

Purpose Among various psychosocial factors, negative social comparison, attention blocking to stimuli, and cognitive interference via information overload are considered most critical in hindering the effective performance improvement of computer-based idea generation. Given that the effect of negative social comparison along with a plausible solution based on the notion of performance feedback and goal setting has been successfully addressed, this study focused on the remaining issues of "attention blocking to stimuli and cognitive interference via information overload" and attempted to find a way to alleviate the effect of such process losses on performance. Design/methodology/approach A 2 × 4 between-subjects design was used, crossing cognitive ability (high and low) and personality (extroversion and introversion). Five subjects per each treatment were randomly selected to make the sample size equal. The group simulator was used to measure individual-level performance. The dependent variables were the quantity of and quality score of ideas. The manner by which these performance measures were operationalized was consistent with prior studies. An additional analysis using the number of diverse ideas was also conducted. Findings Three arguments were made in this study: (1) high cognitive individuals would perform better than low cognitive individuals, (2) extraverted individuals would perform better than introverted individuals, and (3) cognitive ability and personality would interact such that individuals in Q1 would have the highest performance. Cognitive ability had an effect on quality not quantity. Personality had an effect on both quantity and quality. An interaction between cognitive ability and personality was not found due to small sample size despite the use of the group simulator.

• 대한한방내과학회지
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• 제38권6호
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• pp.877-890
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• 2017

Objectives: Lonicerae flos (LF), a dried flower part of Lonicera japonica Thunb., has been widely used in Korean medicine as anti-inflammatory and antioxidative agent. The purpose of this study was to determine the cardioprotective effects of LF, through potential antioxidant effects, on the pressure overload (PO)-induced heart failure (HF) in C57BL/6 mice after transverse aortic constriction (TAC) surgery. Methods: Resveratrol (10 mg/kg body weight) or LF (125, 250 or 500 mg/kg body weight) was orally administered, once daily for 14 days, starting 14 days after TAC surgery. Changes in the mortality, body weights, heart weights, histopathology of the heart, and antioxidant defense systems of the heart were analyzed. Results: Marked and noticeable increases of heart weights, mortalities, and hypertrophic, focal, and lytic fibrotic histological changes in the LVs were observed, with destruction of heart antioxidant defense systems after surgery. However, HF signs, induced by TAC surgery through PO, and destruction of heart antioxidant defense systems were significantly and dose-dependently inhibited by 14 days of maintained oral treatment with LF 500, 250 or 125 mg/kg. Treatment with 250 mg/kg LF was comparable to treatment with 10 mg/kg resveratrol. Conclusions: The results in this study suggest that oral administration of LF favorably relieves PO-induced HF following TAC, through increase of heart antioxidant defense systems. The overall effects of 250 mg/kg LF were similar to those of 10 mg/kg resveratrol. More detailed mechanistic studies should be conducted in the future, with screening of the biologically active compounds in LF.

• Toxicological Research
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• 제31권4호
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• pp.347-354
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• 2015

Excess manganese (Mn) is neurotoxic. Increased manganese stores in the brain are associated with a number of behavioral problems, including motor dysfunction, memory loss and psychiatric disorders. We previously showed that the transport and neurotoxicity of manganese after intranasal instillation of the metal are altered in Hfe-deficient mice, a mouse model of the iron overload disorder hereditary hemochromatosis (HH). However, it is not fully understood whether loss of Hfe function modifies Mn neurotoxicity after ingestion. To investigate the role of Hfe in oral Mn toxicity, we exposed Hfe-knockout ($Hfe^{-/-}$) and their control wild-type ($Hfe^{+/+}$) mice to $MnCl_2$ in drinking water (5 mg/mL) for 5 weeks. Motor coordination and spatial memory capacity were determined by the rotarod test and the Barnes maze test, respectively. Brain and liver metal levels were analyzed by inductively coupled plasma mass spectrometry. Compared with the water-drinking group, mice drinking Mn significantly increased Mn concentrations in the liver and brain of both genotypes. Mn exposure decreased iron levels in the liver, but not in the brain. Neither Mn nor Hfe deficiency altered tissue concentrations of copper or zinc. The rotarod test showed that Mn exposure decreased motor skills in $Hfe^{+/+}$ mice, but not in $Hfe^{-/-}$ mice (p = 0.023). In the Barns maze test, latency to find the target hole was not altered in Mn-exposed $Hfe^{+/+}$ compared with water-drinking $Hfe^{+/+}$ mice. However, Mn-exposed $Hfe^{-/-}$ mice spent more time to find the target hole than Mn-drinking $Hfe^{+/+}$ mice (p = 0.028). These data indicate that loss of Hfe function impairs spatial memory upon Mn exposure in drinking water. Our results suggest that individuals with hemochromatosis could be more vulnerable to memory deficits induced by Mn ingestion from our environment. The pathophysiological role of HFE in manganese neurotoxicity should be carefully examined in patients with HFE-associated hemochromatosis and other iron overload disorders.

• 한국콘텐츠학회논문지
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• 제17권12호
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• pp.25-33
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• 2017

상호작용 속도의 증가는 과잉 관계(over-relations)의 문제가 나타날 수 있다. 과잉 관계로 인한 심리적, 시간적 부담으로 SNS에 대한 피로감을 느껴 SNS 이용을 기피하는 이용자들이 생기고 있다. SNS 피로감(fatigue), SNS 불안감(anxiety) 등 SNS 이용으로 인해 발생된 부작용에 관한 사항들은 'SNS 스트레스'라고 볼 수 있다. 본 연구에서는 SNS에 대한 부정적인 측면을 스트레스라는 관점에서 살펴보며, 스트레스의 발생 원인을 상호작용의 과잉에서 찾고자 한다. 본 연구는 페이스북 이용자들을 대상으로 총 261부를 분석에 활용하였다. SEM(Structural Equation Model) 분석 결과, 모든 연구가설이 채택되었다. 정보공유와 커뮤니케이션 모두 사회적 상호작용 과부하에 긍정적인 영향을 미쳤으며, 사회적 상호작용 과부하가 스트레스를 불러일으키는 것으로 나타났다. 본 연구는 실증적으로 SNS 피로감을 유발시키는 원인으로 상호작용성을 대입해 SNS가 가진 특징이 오히려 부정적인 결과를 초래할 수 있다는 것을 검증하였다는 점에서 의의가 있다.

• 한국정보과학회논문지:컴퓨팅의 실제 및 레터
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• 제12권5호
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• pp.312-325
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• 2006

EAI나 B2BI와 같은 통합 어플리케이션들은 짧은 시간 동안의 서비스 요청 폭주로 인한 과부하시에도 대용량의 I/O기반 트랜잭션들을 안정적으로 처리할 수 있는 신뢰성 있는 시스템을 필요로 한다. 본 논문에서는 I/O기반 시스템에서 대용량의 거래를 효과적으로 처리할 수 있으며 짧은 시간 동안의 거래 요청 폭주로 인한 과부하시에도 안정적으로 서비스를 제공할 수 있는 Peak Load Control(PLC)기반의 Worker-Linker 패턴을 제시한다. 본 논문에서는 PLC 기법을 위해 지체시간(Delay Time) 알고리즘을 사용한다. 또한 제안한 알고리즘이 가지는 과부하 시의 성능 안정성을 증명하기 위해 본 논문에서는 Worker-Linker 패턴을 실제 B2BI 시스템에 적용해서 성능 안정성을 증명하기 위한 실험 결과를 제시한다. 실험 결과에 의하면 본 논문에서 제안한 지체시간 알고리즘은 과부하 상태를 안정적으로 통제하는데 효과가 있다.