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Short- and Long-term Effects of Potassium on Renin-Aldosterone System in Hypertensive Rats Fed with Different Amounts of Sodium

  • Kim, Sook-Young;Yang, Eun-Kyung;Park, Jae-Sik;Lee, Won-Jung;Kim, Suhn-Hee
    • The Korean Journal of Physiology
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    • v.25 no.1
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    • pp.69-79
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    • 1991
  • To evaluate the acute and chronic effects of potassium on aldosterone response to different amounts of sodium intake, two series of experiments were conducted. In the first series of experiments, when the plasma K level was increased acutely by KCI infusion $(20\;{\mu}g/kg/min\;for\;20 min)$, plasma aldosterone concentration increased in both low Na and high Na groups. However, the aldosterone response to K infusion was significantly greater in the low Na than in the high Na groups. In the second series of experiments, rats fed a high K diet chronically showed a significantly higher plasma K level than those fed a low K diet. However, plasma Na level was maintained relatively constant independent of the Na intake. Both the plasma renin activity (PRA) and aldosterone levels were inversely related to the Na intake. There was a highly positive correlation between aldosterone level and PRA over a wide range of sodium intakes. However, the slope of the correlation line was distinctly steeper in the K-repleted than in the K-depleted rats. The above results indicate that the adrenotropic action of acute K load was augmented in the presence of high plasma renin levels. However, when plasna K level was elevated chronically by a high-K diet, aldosterone secretion was markedly stimulated, although the plasma lenin levels were suppressed.

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Evaluation of Fluid Forces Acting on Offshore Structures Placed in the Vicinity of Underwater Shoal (수중 천퇴 인근에 설치된 해양구조물에 작용하는 유체력 결정에 대한 고찰)

  • Chun, In-Sik;Min, In-Ki;Sim, Jae-Seol
    • Journal of Korean Society of Coastal and Ocean Engineers
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    • v.19 no.2
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    • pp.136-145
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    • 2007
  • When waves propagating over an underwater shoal break at the top of the shoal, wave heights are drastically decreased in the downstream breaking zone, but a secondary current shooting downstream with strong velocity can be induced by the breaking waves themselves. In the case that an offshore structure is placed in the breaking zone, the estimation of wave farce purely based on the visible wave height may cause an under-design of the structure. Thus, for the safe design of the structure, the breaking wave induced current should be necessarily considered in the comprehensive estimation of design load. In the present study, Boussinesq equation model to calculate the wave height distribution and breaking wave induced current was set up and applied to the scheme of a hydraulic model test previously undertaken. Based on the results of the Boussinesq model, fluid forces acting on the model structure were calculated and compared with the experimental results. The importance of the breaking wave induced current was quantitatively assessed by comparing fluid forces with or without current.

Effect of power resistance intervention on fitness and muscle mass and short physical performance battery in older women adults (파워 저항운동이 여성노인의 체력, 근육량 및 단기운동수행력에 미치는 영향)

  • Oh, Yoo-Sung;Park, Woo-Young
    • Journal of the Korean Applied Science and Technology
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    • v.37 no.1
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    • pp.114-123
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    • 2020
  • The present study aimed the effects of power resistance training(PRT) on fitness, muscle mass and short physical performance battery(SPPB) elderly women. Thirty older woman(aged 70 over years) were divided in two groups : PRT(n=15) and traditional resistance training(TRT)(n=15). The volunteers trained three times a week, during 12weeks. Both groups performed an equal work output with load red color thera-band. Three sets of twelve repetitions of each exercise were performed with rest intervals of 60s between sets. According to the results. Main fitness were significantly difference in grip strength(TRT) and cardiopulmonary. Muscle was not significantly difference. And Timed up and go and 400m walking(TRT) were significantly difference. There is sufficient effects on between training method in fitness, SPPB but PRT training may yield better results compared with TRT.

A STUDY OF THE STRESS DISTRIBUTION ACCORDING TO THE SLOPES OF THE CHIDING PLANES OF THE ABUTMENTS (지대치 유도면의 기울기에 따른 응력 분포에 대한 연구)

  • Lee, Cheong-Hee
    • The Journal of Korean Academy of Prosthodontics
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    • v.36 no.2
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    • pp.293-301
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    • 1998
  • The purpose of this study was to investigate the effects of load on root that was applied to edentulous area in three simulated situation, in each case the guiding planes of abutment were right vertical, 95 degrees, or 100 degrees to residual ridge. The 2-dimensional finite element method was used and the finite element model was prepared as fellows. Right mandibular 1st and 2nd molar was lost and the 2nd premolar with distal rest was used as primary abutment which had three different degrees of guiding plane. Then 150N of compressive force was applied to central fossae of the 1st and 2nd molars and von Mises stress and displacement was measured. The results were as follows; 1. Irrespective of slopes of guiding planes, the stress was concentrated on mesial side of root apex and distal side of coronal portion of root, in particular on junction with distal alveolar bone. As slopes of guiding planes were increased. stress on root and compact bone surrounding abutment was increased but no considerable effect was seen on compact bone of residual ridge. 2. Distal side of coronal portion of root limited by periodontal ligament was displaced distally and mesial side of apical portion was mesially. With slope of guiding plane increasing, the pattern of displacement was similar with one another but the quantity was increased. 3. Both abutment & alveolar bone were displaced downward and root of abutment, especially distal side of coronal portion, was displaced severely. As the guiding plane was tiffed more mesially over $90^{\circ}$, the degree of displacement was also increased.

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A Study on Changes in Biomechanical Characteristics of the Foot with Respect to Wedge-type Insole Thickness (키높이 인솔두께에 따른 족부의 생체역학적 특성변화에 대한 연구)

  • Park, T.H.;Jung, T.G.;Han, D.W.;Lee, Sung-Jae
    • Journal of Biomedical Engineering Research
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    • v.34 no.2
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    • pp.80-90
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    • 2013
  • Recently, functional insoles of wedge-type it is for the young to raise their height inserted between insole and heel cause foot pain and disease. Additionally, these have a problem with stability and excessively load-bearing during gait like high-heel shoes. In this study, we compared the changes in biomechanical characteristics of foot with different insole thickness then we will utilize for the development of the insole with the purpose of relieving the pain and disease. Subjects(male, n = 6) measured COP(center of pressure) and PCP(peak contact pressure) on the treadmill(140cm/s) using F-scan system and different insole thickness(0~50 mm) between sole and plantar surface during gait. Also, we computed changes of stresses at the foot using finite element model with various insole thickness during toe-off phase. COP moved anterior and medial direction and, PCP was increased at medial forefoot surface, $1^{st}$ and $2^{nd}$ metatarsophalangeal, ($9%{\uparrow}$) with thicker insoles and it was show sensitive increment as the insole thickness was increased from 40 mm to 50 mm. Change of the stress at the soft-tissue of plantar surface, $1^{st}$ metatarsal head represents rapid growth($36%{\uparrow}$). Also, lateral moments were increased over the 100% near the $1^{st}$ metatarsal as the insole thickness was increased from 0 mm to 30 mm. And it is show sensitive increment as the insole thickness changed 10 mm to 20 mm. As a result, it was expected that use of excessively thick insoles might cause unwanted foot pain at the forefoot region. Therefore, insole thickness under 30 mm was selected.

A Study on the Characteristics of High Temperature and Mechanisms for Creep Deformation of AZ31 Mg Alloy (AZ31마그네슘 합금의 고온특성 및 크리이프 변형기구에 관한연구)

  • Kang, D.M.;An, J.O.
    • Journal of Power System Engineering
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    • v.9 no.4
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    • pp.96-101
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    • 2005
  • Magnesium alloys have been widely used for many structural components of automobiles and aircraft because of high specific strength and good cast ability in spite of hexagonal closed-packed crystal structure of pure magnesium. In this study, uniaxial tension tests at high temperature and creep tests are done in order to investigate the characteristics of high temperature and mechanisms for creep deformation of AZ31 Mg alloy. Yield stress and ultimate tensile stress decreased with increasing temperature, but elongation increased from results of uniaxial tension test at high temperature. The apparent activation energy Qc, the applied stress exponent n and rupture life have been determined during creep of AZ31 Mg alloy over the temperature range of 473K to 573K and stress range of 23.42 MPa to 93.59 MPa, respectively, in order to investigate the creep behavior. Constant load creep tests were carried out in the equipment including automatic temperature controller, whose data are sent to computer. At around the temperature of $473K{\sim}493K$ and under the stress level of $62.43{\sim}93.59%MPa$, and again at around the temperature of $553K{\sim}573K$ and under the stress level of $23.42{\sim}39.00MPa$, the creep behavior obeyed a simple power-law relating steady state creep rate to applied stress and the activation energy for the creep deformation was nearly equal, respectively, and a little low to that of the self diffusion of Mg alloy including aluminum. Also rupture surfaces at high temperature have had bigger dimples than those at lower temperature by SEM.

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A Study on BASINS/WinHSPF for Evaluation of Non-point Source Reduction Efficiency in the Upstream of Nam-Han River Watershed (BASINS/WinHSPF를 이용한 남한강 상류 유역의 비점오염원 저감효율평가)

  • Yoon, Chun-Gyeong;Shin, Ah-Hyun;Jung, Kwang-Wook;Jang, Jae-Ho
    • Journal of Korean Society on Water Environment
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    • v.23 no.6
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    • pp.951-960
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    • 2007
  • Window interface to Hydrological Simulation Program-FORTRAN (WinHSPF) developed by the United States Environmental Protection Agency (EPA) was applied to the upstream of Nam-Han river watershed to examine its applicability for loading estimates in watershed scale and to evaluate non-point source control scenarios using BMPRAC in WinHSPF. The WinHSPF model was calibrated and verified for water flow using Ministry of Construction and Transportation (MOCT, 3 stations, 2003~2005) and water qualities using Ministry of Environment (MOE, 5 station, 2000~2006). Water flow and water quality simulation results were also satisfactory over the total simulation period. But outliers were occurred in the time series data of TN and TP at some regions and periods. Therefore, it required more profit calibration process for more various parameters. As a result, all the study was performed within the expectation considering the complexity of the watershed, pollutant sources and land uses intermixed in the watershed. The estimated pollutant load for annual average about $BOD_5$, T-N and T-P respectively. Nonpoint source loading had a great portion of total pollutant loading, about 86.5~95.2%. In WinHSPF, BMPRAC was applied to evaluate non-point source control scenarios (constructed wetland, wet detention ponds and infiltration basins). All the scenarios showed efficiency of non-point source removal. Overall, the HSPF model is adequate for simulating watersheds characteristics, and its application is recommended for watershed management and evaluation of best management practices.

A Study on Dynamic Characteristics of Hydraulic Motor Brake System with Counter Balance Valve (카운터 밸런스 밸브를 내장한 유압 모터 브레이크 시스템의 동특성)

  • Yun, So-Nam;Lee, Ill-Yeong
    • Journal of the Korean Society of Fisheries and Ocean Technology
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    • v.29 no.3
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    • pp.214-219
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    • 1993
  • Counter balance valve is used as one part of hydraulic motor brake system. The function of this valve is to protect over-run or free falling of inertia load. But occasionally the brake system with counter balance valve makes some undesirable problems such as pressure surges or vibrations. These problems may hurt system safety and driver's conformability. Nevertheless, studies on dynamic characteristics of hydraulic system including counter balance valve are very rare, so further accumulation of research results are required. In this study, for the purpose of easy estimation about dynamic characteristics of hydraulic system including counter balance valve, precise formulation describing fluid dynamics and valve dynamics under various boundary conditions were made. The equations obtained in the preceding process include some parameters that must be got experimentally. Flow coefficients of valve and choke are the most significant ones among the parameters. So these parameters are obtained experimentally in this study, and experimental equations obtained from the experimental data were used for numerical calculation. The equations were analysed by numerical integration using Runge-Kutta method, because the equations contain various nonlinear terms. From the numerical analysis, it was verified that the dynamic response of counter balance valve and pressure variation at each elements can be estimated very easily. So the analysing method developed in this study enabled very easy estimating the relation between the performances of counter balance valve and various physical parameters related to the valve. Conclusively, it is said that the results obtained in this study can be used very usefully to develop a new type counter balance valve or to apply the valve to actual hydraulic system for various industrial equipments.

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Appropriateness Evaluation of Rural House Collapse Prepare Disaster Shelter Member - Focusing on the Numerical Analysis - (농촌 주택붕괴 대비 방재쉘터의 부재 적정성 평가 - 수치해석을 중심으로 -)

  • Oh, Hyeonmun;Kim, Jungmeyon;Lee, Eungbeom;Lim, Changsu;Kim, Yongseong
    • Journal of The Korean Society of Agricultural Engineers
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    • v.59 no.5
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    • pp.51-60
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    • 2017
  • This research is a basic study to minimize the risk of disaster (earthquakes and landslides) for rural residential houses. In this study, three-dimensional numerical analysis was performed by varying the diameter (D), thickness (T) and the spacing of longitudinal members (C.T.C) of duralumin and galvanized steel pipe as the materials of main members in order to carry out the analysis of the dimension and the applied load of shelter for disaster prevention, and to evaluate the eligibility of members that can satisfy safety and usability. From the evaluation results of the member eligibility by the above numerical analysis, it was found that duralumin has a great influence on the member diameter (D) and thickness (T), and in the case of galvanized steel pipe, its spacing of longitudinal members has a huge amount of influence over the member force, so it is considered that the duralumin and galvanized steel pipe materials can be used as materials for the main members of disaster prevention shelters in terms of safety and usability.

Effect of Lubricant with Nanodiamond Particles in Sliding Friction

  • Adzaman, M.H.;Rahman, A.;Lee, Y.Z.;Kim, S.S.
    • Tribology and Lubricants
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    • v.31 no.4
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    • pp.183-188
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    • 2015
  • This paper presents the experimental effects of lubricant with nanodiamond particles in sliding friction. In order to improve the performance of lubricants many additives are used, such as MoS2, cadmium chloride, indium, sulfides, and phosphides. These additives are harmful to human health and to the environment, so alternatives are necessary. One such alternative is nanodiamond powder, which has a large surface area. In order to investigate the effect of nanodiamonds in lubricants under sliding friction, they are dispersed in the lubricant at a variety of concentrations (0 wt%, 0.1 wt%, 0.3 wt%, 0.5 wt%, and 1 wt%) using the matrix synthesis method. Friction and wear tests are performed according to the ASTM G99 method using a pin-on-disc tester at room temperature. The specimens used in this experiment are AISI 52100 ball bearings and AISI 1020 steel discs. During the test, lubricant mixed with nanodiamond is supplied constantly to keep the two bodies separated by a lubricant film. To maintain boundary lubrication, the speed is set to 0.18 m/s and a load of 294 N is applied to the disc through the pin. Results are recorded by using workbench software over the test duration of 10 minutes. Experimental results show that when the concentration of nanodiamond increases, the coefficient of friction decreases. However, above a nanodiamond concentration of 0.5 wt%, both the coefficient of friction and wear volume increase. From this experiment, the optimum concentration of nanodiamond showing a minimum coefficient of friction of 0.09 and minimum wear volume of 0.82 nm2 was 0.5 wt%.