• 한국우주과학회:학술대회논문집(한국우주과학회보)
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• 한국우주과학회 2009년도 한국우주과학회보 제18권2호
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• pp.36.3-37
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• 2009

This is an attempt to improve a formula to predict variations of geomagnetic storm indices (Dst) from solar wind parameters. A formula which is most widely accepted was given by Burton et al. (1975) over 30 years ago. Their formula is: dDst*/dt = Q(t) - Dst*(t)/$\tau$, where Q(t) is the Dst injection rate given by the convolution of dawn-to-dusk electric field generated by southward solar wind magnetic field and some response function. However, they did not clearly specify the response function. As a result, misunderstanding seems to be prevailing that the injection rate is proportional to the dawn-to-dusk electric field. In this study we tried to determine the response function by examining 12 intense geomagnetic storms with minimum Dst < -200 nT for which solar wind data are available. The method is as follows. First we assume the form of response function that is specified by several time constants, so that we can calculate the injection rate Q1(t) from the solar wind data. On the other hand, Burton et al. expression provide the observed injection rate Q2(t) = dDst*/dt + Dst*(t)/$\tau$. Thus, it is possible to determine the time constants of response function by a least-squares method to minimize the difference between Q1(t) and Q2(t). We have found this simple method successful enough to reproduce the observed Dst variations from the corresponding solar wind data. The present result provides a scheme to predict the development of Dst 30 minutes to 1 hour in advance by using the real time solar wind data from the ACE spacecraft.

• 대한토목학회논문집
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• 제26권2A호
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• pp.319-326
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• 2006

본 논문에서는 가정응력장과 수정된 형상함수를 이용한 새로운 8절점 hybrid/mixed 평면응력요소를 제시하였다. 가정응력장은 비적합 변위모드로부터 유도하였으며, 이는 요소의 찌그러짐에 대한 민감도를 완화시켜준다. 그리고 Cartesian 좌표계에서 9절점 등매개변수 요소와 동일한 조건하에서 2차 변위를 정확히 보간하도록 수정한 형상함수를 사용하였다. 제시한 8절점 hybrid/mixed 평면응력요소(HQ8-$14{\beta}$)의 수치해석에 대한 정확성과 효율성을 검증하기 위해 기존의 참고문헌들과 비교, 분석하였다. 그 결과 본 논문에서 제시한 요소는 요소가 왜곡된 경우를 포함하여 우수한 성능을 보였다.

• 영어영문학
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• 제55권1호
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• pp.177-198
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• 2009

How are we approach the fourteenth chapter of Ulysses known as 'The Oxen of the Sun' in this globalized age of hyper-theorization? My paper argues that examining the wide reverberations set off by Derrida's comment in "Ulysses Gramophone"-"Everything has already happened to us with Ulysses"-in relation to the central textual theme of cosmopolitanism may provide a reading that not only pays due respect to the critical legacy of the early structuralist interpretations but equally takes into account the political sensibilities of our time. The neologism 'chaosmopolitanism,'in fact, serves as that very critical measure designed to bridge the gap separating the long tradition of Western Eurocentric discourse on cosmopolitanism on the one hand and the geopolitical background conditioning its discursive possibility, namely, the chaotic condition of international colonialism on the other, whose exemplary, and exemplarily creative, fusion bears none other name than Ulysses. But the idea of chaosmopolitanism gains its conceptual leverage on yet another, no less pivotal register, for, just as with Derrida's first-person plural pronoun, the trope leads us to reflect on our own situatedness in the East Asian region in light of Joyce's unabashedly universalist vision, whose over-arching textual purview nonetheless leaves the space called the Far East in the singular position of virtual exclusion. What does it then mean to enjoy Joyce's "chaffering allincluding most farraginous chronicle" in light of our East Asian perspective? To this second question, my inquiry turns to the dual theme of enjoyment and debt as they are problematized by Stephen Dedalus' telegram to Mulligan, which reads, "the sentimentalist is he who would enjoy without incurring the immense debtorship for a thing done." Itself a quotation from George Meredith's novel The Ordeal of Richard Feverel, the transcribed message invites us to reconsider the scrupulous endeavor underwriting Joyce's signatory gusto, but at the same time forcing us to confront and reassess our own debt to the problematic heritage known as Western literature or, to borrow Derrida's expression, Abrahamic language.

• 한국작물학회:학술대회논문집
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• 한국작물학회 2022년도 추계학술대회
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• pp.289-289
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• 2022

Waterlogging tolerance of corn is one of the important factor for cultivate in paddy soil condition to increase cultivation area and self-sufficiency of corn in Korea. In order to develop elite waterlogging tolerance corn, the new corn lines bred by crossing wild corn, Teosinte, and cultivated corn inbred lines. Five accessions among the 2 species, Zea mays sub spp. mexicana and Zea mays spp. parviglumis, of 81 Teosinte were selected through the waterlogging treatment. The waterlogging treatments were implemented for 7 days at the seedling(V3) stage. The inbred lines were developed by crossing 5 teosinte accessions and cultivated corn lines and they were estimated waterlogging tolerance. It was screened and analyzed the metabolites extracted from roots of 19KT-32(KS141 × teosinte) that was treated waterlogging. We selected 8 of 180 metabolites like as γ-aminobutyric acid(GABA), putrescine, citrulline, Gly, and Ala that expression was remarkably changed over 2.5-times, 7 metabolites increased and 1 metabolite decreased in waterlogging, respectively. Glutamate decarboxylase(GAD) catalyzing GABA accumulation gene have 10 haplotypes, and exon1 was highly conserved, but identified to 135 SNPs after the first intron. Among the 135 SNPs, the number of transversion mutations (52) surpassed the number of transition mutations (38). Most of metabolites were related to abiotic stress in plant that it regulated to pH, osmotic pressure K⁺/Ca⁺⁺ and ATPase activity. We are analyzing the association using these results for increase breeding efficiency.

• 치위생과학회지
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• 제23권4호
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• pp.296-301
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• 2023

Background: Periodontal disease is a major cause of tooth loss in adults and is a representative oral disease commonly suffered by most people around the world. Mainly the proliferation of Gram-negative bacteria and secreted virulence factors cause an inflammatory response and destroy periodontal tissue. Gossypetin, isolated from Hibiscus sabdariffa L, is known to have various pharmacological effects, including antibacterial and anticancer activities. We aimed to confirm the anti-inflammatory effect of gossypetin through interleukin-6 (IL-6) regulation in human gingival fibroblasts (HGFs) stimulated with lipopolysaccharide (LPS) of Porphyromonas gingivalis, a major cause of adult periodontitis. Methods: CCK-8 assay was performed to confirm the concentration-dependent cytotoxicity of gossypetin against HGFs. The secretion level and mRNA expression of IL-6, an inflammation-related cytokine, and the effect of gossypetin on these in HGFs stimulated with P. gingivalis LPS were confirmed by ELISA and qRT-PCR analysis, respectively. Results: Up to a concentration of 100 µM gossypetin with or without P. gingivalis LPS, the survival rate for HGFs was maintained at over 95% and showed no toxicity. ELISA and qRT-PCR analysis results showed that P. gingivalis LPS increased IL-6 secretion and mRNA levels in HGFs compared to the control group. However, this increase in IL-6 was significantly down-regulated by gossypetin treatment in a dose-dependent manner. In particular, 80 µM gossypetin inhibited IL-6 production to the level of the control group. Conclusion: These results indicated that gossypetin attenuated IL-6 production in HGFs stimulated by P. gingivalis LPS, which may ultimately suppress the inflammatory response in periodontal tissue. Therefore, gossypetin may have potential as a natural ingredient for the prevention and treatment of periodontal disease.

• 치위생과학회지
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• 제23권4호
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• pp.369-377
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• 2023

Background: In this study, we investigated the potential use of keratin for oral tissue regeneration. Keratin is well-known for its effectiveness in skin regeneration by promoting keratinization and enhancing the elasticity and activity of fibroblasts. Because of its structural stability, high storability, biocompatibility, and safety in humans, existing research has predominantly focused on its role in skin wound healing. Herein, we propose using keratin proteins as biocompatible materials for dental applications. Methods: To assess the suitability of alpha-keratin protein as a substrate for cell culture, keratin was extracted from human hair via PEGylation. Viabilities of primary human gingival fibroblasts (HGFs) and human oral keratinocytes (HOKs) were assessed. Fluorescence immunostaining and migration assays were conducted using a fluorescence microscope and confocal laser scanning microscope. Wound healing and migration assays were performed using automated software to analyze the experimental readout and gap closure rate. Results: We confirmed the extraction of alpha-keratin and formation of the PEG-g-keratin complex. Treatment of HGFs with keratin protein at a concentration of 5 mg/ml promoted proliferation and maintained cell viability in the test group compared to the control group. HOKs treated with 5 mg/ml keratin exhibited a slight decrease in cell proliferation and activity after 48 hours compared to the untreated group, followed by an increase after 72 hours. Wound healing and migration assays revealed rapid closure of the area covered by HOKs over time following keratin treatment. Additionally, HOKs exhibited changes in cell morphology and increased the expression of the mesenchymal marker vimentin. Conclusion: Our study demonstrated the potential of hair keratin for soft tissue regeneration, with potential future applications in clinical settings for wound healing.

• 대한중풍순환신경학회지
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• 제24권1호
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• pp.67-76
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• 2023

Post-stroke aggression refers to aggressive behaviors and languages which are occurred after stroke. In stroke patients, over 15% suffer from the anger and the symptom lowers the quality of life of the patients, family, and caregivers. After diagnosing post-stroke aggression, selective serotonin re-uptake inhibitor(SSRI) and beta-blocker, beta adrenergic agonist treatment usually underwent to treat the anger and anxiety of the patient. In the present case, a 81-year-old female patient with post-stroke aggression underwent Korean medical treatment by Jodeungsan and Ukgansan for 49 days. The effect of the treatment was assessed with State-Trait Anger Expression Inventory(STAXI) per a week, roaming time per a week and roaming frequency per a week. After the treatment, STAXI score, roaming time, and roaming frequecy decreased, and the patient could successfully cease to take beta-blocker, which she started to take for treating her aggression, without any side-effects. This case report suggests that Ukgansan might be an effective option with post-stroke aggression patients taking medication including beta-blocker.

• Animal Bioscience
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• 제36권12호
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• pp.1889-1897
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• 2023

Objective: 'Cultured meat' has been suggested as means of solving the problems associated with overpopulation and gas emissions. Satellite cells are a major component in the production of cultured meat; however, these cells cannot be maintained in vitro over long periods. Fibronectin is a glycoprotein that affects biological processes such as cell adhesion, differentiation, and migration. Unfortunately, the characteristics of porcine satellite cells grown in a long-term culture when exposed to fibronectin-coated dishes are unknown. The objective of this study was to investigate the appropriate concentration of fibronectin coated dishes for proliferation and maintenance of porcine satellite cells at long-term culture. Methods: In this study, we isolated the satellite cells and fibroblast cells with pre-plating method. We next analyzed the cell doubling time, cell cycle, and rate of expressed paired box 7 (Pax7) and myogenic differentiation 1 (MyoD1) in porcine satellite cells cultured with 20 ㎍/mL of fibronectin-, gelatin-, and non-coated dishes at early and late passage. We then analyzed the proliferation of porcine satellite cells with various concentrations of mixed gelatin/fibronectin. We next determined the optimal concentration of fibronectin that would encourage proliferation and maintenance of porcine satellite cells in a long-term culture. Results: Doubling time was lowest when 20 ㎍/mL of fibronectin was used (as tested during an early and late passage). Levels of expressed Pax7 and MyoD1, assessed using immunocytochemistry, were highest in cells grown using fibronectin-coated dishes. The proliferation of gelatin/fibronectin mixed coatings had no significant effect on porcine satellite cells. The concentration of 5 ㎍/mL fibronectin coated dishes showed the lowest doubling time and maintained expression of Pax7. Conclusion: Fibronectin with 5㎍/mL effectively maintains porcine satellite cells, a discovery that will be of interest to those developing the next generation of artificial meats.

• International Journal of Advanced Culture Technology
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• 제11권4호
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• pp.223-232
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• 2023

The purpose of this study is to determine the impact of social network sports community consciousness on loyalty and sports attitude. In order to achieve this research purpose, the population of the study was selected as adult men and women over the age of 20 who are active in the social network sports community in 2022. The sampling method used cluster random sampling to select a total of 300 people, 150 men and 150 women, as research subjects. The survey tool used was the questionnaire method, and the questionnaire whose reliability and validity had been verified in previous studies at home and abroad was used by requoting, modifying, or supplementing it to suit the purpose of this study. It was also structured on a 5-point scale. Frequency analysis, factor analysis, reliability analysis, simple regression analysis, and multiple regression analysis were performed on the collected data using the statistical program SPSS Windows 20.0 Version. The results obtained through this process are as follows. First, social network sports community consciousness was found to have a partial effect on loyalty. Second, social network sports community consciousness was found to have a partial effect on sports attitudes. Third, social network sports community loyalty was found to have a partial effect on sports attitudes. Considering these results, various activities such as decision-making process, relationship formation, and opinion expression of modern people are carried out by the O-line community. In addition, while in the past it was a format that led from offline activities to online activities, currently, there are more and more formats that lead from online activities to offline activities. Therefore, modern people's SNS sports community activities provide many experiences, which creates a sense of community and sports attitudes are formed based on this. This can be said to lead to loyal activities.

• The Korean Journal of Physiology and Pharmacology
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• 제28권4호
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• pp.303-312
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• 2024

Atopic dermatitis (AD) is the most common inflammatory pruritic skin disease worldwide, characterized by the infiltration of multiple pathogenic T lymphocytes and histological symptoms such as epidermal and dermal thickening. This study aims to investigate the effect of vinpocetine (Vinp; a phosphodiesterase 1 inhibitor) on a 1-chloro-2,4-dinitrobenzene (DNCB)-induced AD-like model. DNCB (1%) was administered on day 1 in the AD model. Subsequently, from day 14 onward, mice in each group (Vinp-treated groups: 1 mg/kg and 2 mg/kg and dexamethasone-treated group: 2 mg/kg) were administered 100 µl of a specific drug daily, whereas 0.2% DNCB was administered every other day for 30 min over 14 days. The Vinp-treated groups showed improved Eczema Area and Severity Index scores and trans-epidermal water loss, indicating the efficacy of Vinp in improving AD and enhancing skin barrier function. Histological analysis further confirmed the reduction in hyperplasia of the epidermis and the infiltration of inflammatory cells, including macrophages, eosinophils, and mast cells, with Vinp treatment. Moreover, Vinp reduced serum concentrations of IgE, interleukin (IL)-6, IL-13, and monocyte chemotactic protein-1. The mRNA levels of IL-1β, IL-6, Thymic stromal lymphopoietin, and transforming growth factor-beta (TGF-β) were reduced by Vinp treatment. Reduction of TGF-β protein by Vinp in skin tissue was also observed. Collectively, our results underscore the effectiveness of Vinp in mitigating DNCB-induced AD by modulating the expression of various biomarkers. Consequently, Vinp is a promising therapeutic candidate for treating AD.