• Journal of Veterinary Clinics
• /
• v.30 no.4
• /
• pp.310-314
• /
• 2013

A 12-year-old, female mixed breed dog presented with a vaginal mass protruding outside the vulva. The patient was non-gravid, with normal defecation and urination. Serum chemistry revealed azotemia and increased alkaline phosphatase. Hematology findings were normal. Blood electrolytes showed mild hypernatremia. Ultrasonography demonstrated severely enlarged uterine horns, a uterine body with anechoic to hypoechoic fluids, and a focal hypoechoic area within the mass of the right uterine tube. On computed tomography, metastasis was not confirmed. Other computed tomography findings suggested a right ovarian cyst, an enlarged, fluid-filled uterus, and an enlarged vagina with a mass. Ovariohysterectomy, episiotomy, and vaginectomy were performed. The case was diagnosed as uterine tube adenocarcinoma, vaginal fibroma, and pyometra. This case is the first reported concurrent occurrence in dogs.

• Korean Journal of Veterinary Research
• /
• v.15 no.2
• /
• pp.181-185
• /
• 1975

The experiment was carried out to determine the concentrations of total calcium and inorganic phosphorus of thirty rera obtained from pregnant Holitein cows, six sera from normal non-pregnant cows with one month after delivery, six sera from cows with ovarian cyst and six sera from heifer of sixteen months old. The changes of total calcium and inorganic phosphorus were observed on the 2nd, 4th, 6th, 8th, and l0th month of gestation. The results obtained in this work were summarized as follows: 1. The mean values of total serum calcium obtained from the pregnant group were $9.59{\pm}0.34mg/100ml$, from the non-pregnant group $10.23{\pm}0.47mg/100ml$, from the infertility grou $10.37{\pm}0.27mg/100ml$, and from the heifer group $10.07{\pm}0.20mg/ml$. The change of total serum calcium values in the pregnant group revealed the tendency of decrease as gestation progresses and the lowest value appeared on the sixth month. The mean value of total serum calcium in the pregnant group was lower than those of the other groups, but the differences were not statistically significant. 2. The mean values of serum inorganic phosphorus obtained from the pregnant group were $5.82{\pm}0.31mg/100ml$, from the non-pregnant group $5.92{\pm}0.44mg/100ml$, from the infertility group $5.80{\pm}0.49mg/100ml$, and from the heifer group $5.10{\pm}0.32mg/100ml$. The change during pregnancy showed a slight fall and the lowest value appeared on the sixth month. The differences of serum inorganic phosphorus values between the pregnant group and the other adult groups were not significant, but these adult groups showed a significantly higher value than that of heifer group (p<0.05).

• The Journal of Korean Obstetrics and Gynecology
• /
• v.31 no.3
• /
• pp.50-60
• /
• 2018

Objectives: The purpose of this study was to investigate the treatment methods of chronic pelvic pain, which have no definite treatment methods, and to provide basic data on clinical trials and clinical practical guideline in Korean Medicine related to chronic pelvic pain. Methods: The key words such as 'pelvic pain', 'pelycalgia' are used for the research through 'OASIS, KTKP, RISS, DBpia, KISS'. Total 6 studies were analyzed. Results: 6 studies were chronic pelvic pain case reports. Case reports 6 studies covered a total of 11 cases. Of these, 4 cases related to adenomyosis, 3 cases of endometriosis, and 2 cases of ovarian cyst. However, there were many cases in which the causative disease was not clear. In addition, the majority of the studies reported on the progress of hospitalization, and all studies used herbal medicine, acupuncture and moxibustion. The duration of treatment ranged from 5 to 30 days for hospitalization and 5 months for outpatient treatment. The most commonly used meridian is Conception Vessel (任脈), and SP6 (三陰交) was the most frequently used acupuncture treatment. The herbal medicine Banchong-san (蟠蔥散) was generally prescribed. Conclusions: The effect on treatment of Korean Medicine for chronic pelvic pain had mostly positive results. However, the number of searched studies, which are insufficient for design or analysis of study, is very limited. We hope that this study will be useful for further clinical studies of chronic pelvic pain.

• Korean Journal of Veterinary Research
• /
• v.14 no.2
• /
• pp.201-205
• /
• 1974

Blood serum from 30 pregnant cows, 6 non-Pregnant cows (one month after delivery), 6 sterile cows (ovarian cyst), and 6 heifers (16 months old) were analyzed for total vitamin E concentration by the ferric chloride-bipyridyl reaction. The pregnant group was determined periodically throughout pregnancy. The results obtained were as follows: 1. The mean value of serum vitamin E level in pregnant group was $0.651{\pm}0.068(SE)mg/100ml$, in non-pregnant group $0.647{\pm}0.119(SE)mg/100ml$, in sterile group $0.488{\pm}0.053(SE)mg/100ml$, and in heifer group $0.083{\pm}0.016(SE)mg/100ml$. Samples below 0.19mg/100ml were net observed and most of the pregnants (83.3%) showed the values of 0.40 to 0.99mg/100ml during pregnancy 2. The difference of vitamin E level between pregnant group and non-pregnant group was net significant, but these trio groups showed a significantly higher value than that of sterile group. On the other hand, in heifer group was recognized significantly lower value compared with adult groups. 3. The change of serum vitamin E level in pregnant group revealed the tendency of decrease as gestation progresses and significantly dropped at the eighth month, thereafter, the value was rose slightly at the tenth month of gestation but no differences were observed. The coefficient of correlation between months and serum vitamin E levels during pregnancy was r=-0.956(p<0.01), and a regression equation was Y (serum vitamin E levels, mg/100ml)=1.034-0.063x(month).

• Journal of Embryo Transfer
• /
• v.12 no.1
• /
• pp.57-66
• /
• 1997

This study was carried out to establish an effective and practical system for commercialization of embryo production techniques by analyzing several factors influencing in vivo embryo production on days and seasons of flushing in Korean native cattle. In vivo embryos were flushed 226 times from 128 donors. The results obtained for the factors influencing in vivo embryo production on days and seasons of flushing were as follows :1.The percentages of fertilized, transferable and freezable embryos by seasons were significantly different in both FSR-P and SUPER-OV(P<0.01). The percentages of them were highest in sunrrner with FS H-P and highest in autumn with SUPER -OV.2. The production of transferable and freezable embryos by flushing days was highest in 8 days with FSH-P, and there was no difference between 7 and 8 days for SUP ER-OV. 3. The failure rates of recovery were 17.0% in SUPER-OV and 21.2% in FSH-P, respectively. The donors superovulated but failed recovery were 8.5% in SUPER-OV and 12.9% in FSH-P, respectively. Nonsuperovulated donors was 8.4% and donors giving less than 2 eggs at recovery was 8.4% in both FSH -P and SUPER-OV 4. The donors returned to normal estrus after superovulation were 34.1% after 1 cycle,39.4% after 2 cycles, and 16.7% after 3 cycles by FSH-P, respectively. For SUPER-OV, they were 55.3, 33.0 and 9.6%, respectively. Generally, normal estrus after the treatment of superovulation was earlier and the occurrence of ovarian cyst was also lower in SUP ER-OV than in FSH-P.5.The percentages of blastocyst in embryos flushed at 7~8 days after estrus were 21. 9% and 54.3% in FSH -P and SUPER-OV, respectively. The development of embryos was faster in SUPER-OV than in FSH-P.(Key words : in vivo embryo, flushing days, superovulation, FSH-P, SUPER-OV)

• Clinical and Experimental Reproductive Medicine
• /
• v.48 no.4
• /
• pp.380-384
• /
• 2021

Theca lutein cysts are rare, benign lesions responsible for gross cystic enlargement of both ovaries during pregnancy. This condition is also termed hyperreactio luteinalis. Elevated human chorionic gonadotropin (hCG) levels or states of hCG hypersensitivity seem to promote these changes, which in up to 30% of patients produce clinical signs of hyperandrogenism. Given the self-limiting course of theca lutein cysts, which are subject to spontaneous postpartum resolution, conservative treatment is the mainstay of patient management. Described herein is a rare case of theca lutein cysts with maternal virilization that failed to regress by 9 months after childbirth. Surgical intervention was eventually undertaken, necessitated by adnexal torsion.

• Korean Journal of Fisheries and Aquatic Sciences
• /
• v.33 no.5
• /
• pp.431-438
• /
• 2000

To clarify the annual reproductive cycle in a rockfish, Sebastes schlegeli, monthly changes in gonadosomatic index (GSI), hepatosomatic index (HSI) and histological feature of gonads and plasma levels of sex steroid hormones ($estradiol-l7{\beta},\;17{\alpha},\;20{\beta}-dihydroxy-4-pregnen-3-one,\;testosterone\;and\;11-ketotestosterone$) were investigated. The annual reproductive cycle in females could be divided into 5 periods as follows: 1) recovery period (June to September): serum level of $estradiol-l7{\beta}$ increased gradually; 2) vitellogenesis period (Septemer to february) : vitellogenic oocytes were obsewed, GSI sustained high value, and serum level of $estradiol-l7{\beta}$ increased; 3) gestation period (February-April): developing larva showed in the ovary, and serum levels of $17{\alpha},\;20{\beta}-dihydroxy-4-pregnen-3-one$ and testosterone increased; 4) partrition period (April to May) : larva were delivered, and value of GSI and serum levels of hormones decreased rapidly; 5) resting period (May to June) : value of GSI and serum levels of $estradiol-l7{\beta}$ and testosterone remained low. The annual reproductive cycle in males could be divided into 6 periods; 1) early maturation period (April to June): value of GSI and serum levels of hormones incresed gradually, cyst of spermatogonia incresed in number, and a small number of cyst of spermatocyte was observed; 2) mid-maturation perid (June to September); value of GSI and serum levels of hormones increased, and germ cells in many cysts were undergoing active sperrnatogenesis; 3) late maturation period (September to November) : value of GSI and serum levels of hormones remained high and spermatozoa were released into the lumina of the seminal lobules; 3) spermatozoa dischaging period (Nobember to December) : the lumina of the seminal lobules were enlarged and filled with mature spermatozoa; 4) degeneration period (December to Februauy)i value of GSI decresed and cyst of spermatocyte were decresed in number; 5) resting period (December to April) : no histological changes of testes were observed, and value of GSI and serum levels of hormones remained low. In November, the lumina of the seminal lobules were filled with mature spermatozoa and sperm masses were present in the ovarian cavity. Thus, copulation in this species occurred in November and December.

• Korean Journal of Ichthyology
• /
• v.6 no.2
• /
• pp.237-243
• /
• 1994

This work was conducted to study sex differentiation in the black sea bream, Acanthopagrus schlegeli (Bleeker), using a histological method for the appearance of primordial germ cell, formation of primitive gonads, differentiation of female and male from newly hatched larva to the ovotestis stage of fish. The 3~4 primordial germ cells of $6.8{\sim}7.2\;{\mu}m$ in size, which were buried under fibrous mesenchymal tissue between gut duct and notochord of pre-larva with a total length (T.L.) of 2.4 mm at 3 days after hatching. The proto-gonial cells were located in the epithelium of the coelom attached with pigment cells of juvenile with 6.4 mm in T.L. at 21 days after hatching. In juvenile of 20.8 mm in T.L. at 59 days after hatching, the proto-gonial cells were migrated to the retro-peritoneum through the lineshaped primitive gonad composed of fibrous mesenchymal tissue. In juvenile of 7.8 em in T.L. at 186 days after hatching, the mitotic division of proto-gonial cell appeared in the lineshaped primitive gonad having many eosinophilic granule cells and abundant fibrous connective tissue. In juvenile of 9.5 em in T.L. at 254 days after hatching, the gonad was occupied by abundant fibrous connective tissue, bundles of spermatocyte and spermatid. In juvenile of 10.5 cm in T.L. at 13 months after hatching, the gonad was divided into cortical layer and medullary layer. The former was composed of bundles of a few spermatocytes and proto-gonial cells, the latter was filled with the fibrous mesenchymal tissue and a few proto-gonial cells. In juvenile of 14.7 em in T.L. at 16 months after hatching, the gonad was separated into ovarian part and testicular part by the fibrous connective tissue. The ovarian part is consisted of ovarian cavity and oocytes of perinucleolus stage. The testicular part was occupied by spermatogonia in the cyst.

• Journal of Veterinary Clinics
• /
• v.24 no.4
• /
• pp.542-549
• /
• 2007

During a designated period(Jan. 2003$\sim$Jun. 2006), a total of 2,051 biopsy and necropsy cases submitted to Veterinary Medical Teaching Hospital of Seoul National University and local practitioners were diagnosed as canine tumors based on microscopic evaluation in the Department of Veterinary Pathology, College of Veterinary Medicine, Seoul National University. Four hundred and twenty of 2,051 tumor specimens excluding mammary(883, 43.1%) and cutaneous(748, 36.5%) tumors were included in this retrospective study. They were composed of genital tumors(189, 45.0%) followed by alimentary(113, 26.9%), hematopoietic(52, 12.4%), urinary(20, 4.8%), bone & joint(15, 3.6%), ocular & otic(9, 2.1%), respiratory(6, 1.4%), endocrine(6, 1.4%), and miscellaneous(10, 2.4%). Particular top ten tumor most frequently diagnosed were seminoma(48, 11.4%) followed by fibrous epulis(38, 9.0%), lymphoma(38, 9.0%), leiomyoma(33, 7.9%), fibroma(26, 6.2%), ovarian cyst(19, 4.5%), melanoma(15, 3.6%), papilloma(14, 3.3%), cystic endometrial hyperplasia(13, 3.1%), granulosa cell tumor(13, 3.1%) in descending order comprising 257(61.2%). The affected age of the animals with ten frequent tumors ranged from 3 months to 17 years old with a mean of 9.2 years old(n=218). There were no significant sex prevalence except female leiomyoma. The top seven anatomical sites of tumors inclusive were gingiva(62, 14.8%), testis(61, 14.5%), ovary(48, 11.4%), vagina(40, 9.5%), uterus(36, 8.6%), lymph node(30, 7.1%), and spleen(21, 5.0%).

• Journal of Sasang Constitutional Medicine
• /
• v.9 no.2
• /
• pp.263-281
• /
• 1997

We studied the relationship between each type which was figured out by the question paper given to the patients who chiefly complained feeling of cold and Sasang constitution. The results are as follows. 1. Diagnoses in woman's disease with feeling of cold(冷病) are abdomnal mass(uterine myoma, ovarian cyst), dysmenorrhea, leukorrhea and infertility, orderly in number. They have commoness in the origin of disease which are stagnation of Qi(氣滯) and blood stasis(血瘀), cold(寒), damp(濕) and we can find the causes of feeling of cold are stagnation of blood(血瘀) and harmness of damp(水毒). 2. In the type of survey through the question paper, the largest number of the origin of that disease is cold, the next is blood stasis and dificiency of Qi(氣虛), dificiency of blood(血虛), stagnation of Qi, damp phlegm(濕痰) etc. 3. (1)The numbers by constitutional assortment of object are like this. Taeumin are 23 persons,Soumin 14 and Soyangin 6, so we can find the feeling of cold turn up evenly in all constitution but the number of Soyangin was relatively small. (2)The inclination of constitutional type is the highest in Soumin and they often have and feel strongly disorders of their body. (3)We could find the corelation of theoretical background of Sasang Medicine in constitutional type of survey. 4. (1)The numbers by constitutional assortment of the patients with feeling of cold and numbness(冷痺症) are like this. Taeumin are 16 persons, Soumin 7 and Soyangin 3, as are like the distribution of 3-(1). (2)The inclination of constitutional type is the highest Soumin, so they have multiple type of differentiation of symptoms and signs and their symptoms is old and severe, therefore they need long time for cure. In all, except the symptom with feeling of cold caused by dificiency of the blood and insufficiency of yang(氣虛와 陽虛) that we meet frequently on clinic is numerous, the number of that caused by stagnation of Qi and blood(氣滯와 血滯) alike dysautonomia is also large. And we can find the feeling of cold turn up evenly in all constitution but the number of Soyangin was relatively small. Within the case of Soumin, they have both dificiency of Qi and blood, have complex source, so their symptoms are old and severe and they need long time for cure. In Taeumin, they are of large number with dificiency of Qi and we think thst that are concerned with the symptom of exterior cold.