• 대한약침학회지
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• 제4권3호
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• pp.101-103
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• 2001

Objective : This study is designed to find out the effects of the Bee-Venom Acupuncture on knee joint with osteoarthritis. Methods :We are investigated that outpatients suffer from knee joint pain deciphered at the division of Acupuncture in Jaseng oriental medicine hospital from the 13, July 1999 to until 11, November 2000. We make an estimated of the score from both before or after its treatment about 70 cases of diagnostic patient with the osteoarthritis of knee joints by biochemical method and X-RAY analysis, we observed in the progress of symptoms. Results: These results found that sex. distinction with a disease caused much more female than male at the ratio of 1 to 5.36 in the proportion of males to females, jobs is mainly ranked with a housewife and approximately 82.9% of cases before our hospital have ever treated at the other clinics or hospitals. On the hand. the distribution interval of a case history is mainly followed by disease in below 6 month, interval of the period-treatment is mainly gone within 3 month and frequency of treatment is examined into 11 to 15 times, more than 16 times and below 10 times, respectively. We are estimated with the score of functional barrier from both before or after its treatment against osteoarthritis' patients and produced in the usefulness from the totally point of fields except the aid-device after its treatment. In summary, these results demonstrated that Bee Venom, Acupuncture enhanced more than 82.9% to the improvement of treatment and P<0.05 considered to be statistically significant. Conclusion: These results suggest that Bee-venom Acupuncture may be playa role in the significant usefulness and have need of actively application for the clinical trials against osteoarthritis' patients.

• Journal of Acupuncture Research
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• 제18권3호
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• pp.35-47
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• 2001

Objective : This study is designed to find out the effects of the Bee Venom-Acupuncture on knee joint with osteoarthritis. Methods : We are investigated that outpatients suffer from knee joint pain deciphered at the division of Acupuncture in Jaseng oriental medicine hospital from the 13, July 1999 to until 11, November 2000. We make an estimated of the score from both before or after its treatment about 70 cases of diagnostic patient with the osteoarthritis of knee joints by biochemical method and X-RAY analysis, we observed in the progress of symptoms. Results : These results found that sex distinction with a disease caused much more female than male at the ratio of 1 to 5.36 in the proportion of males to females, jobs is mainly ranked with a housewife and approximately 82.9% of cases before our hospital have ever treated at the other clinics or hospitals. On the hand, the distribution interval of a case history is mainly followed by disease in below 6 month, interval of the period-treatment is mainly gone within 3 month and frequency of treatment is examined into 11 to 15 times, more than 16 times and below 10 times, respectively. We are estimated with the score of functional barrier from both before or after its treatment aganist osteoarthritis' patients and produced in the usefulness from the totally point of fields except the aid-device after its treatment. In summary, these results demonstrated that Bee Venom, Acupuncture enhanced more than 82.9% to the improvement of treatment and P<0.05 considered to be statistically significant. Conclusion : These results suggest that Bee-venom Acupuncture may be play a role in the significant usefulness and have need of actively application for the clinical trials against osteoarthritis'patients.

• Korean Journal of Acupuncture
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• 제30권1호
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• pp.64-72
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• 2013

목적 : 본 연구는 퇴행성 슬관절염 환자의 통증을 줄이고 증상을 개선하는데 있어 현재 침구임상에서 활용되고 있는 온침이 침보다 더욱 유효한지를 알아보기 위하여 임상연구로 시행되었다. 방법 : 총 76명의 퇴행성 슬관절염 지원자가 연구에 참가하였으며, 이들 모두는 선정기준과 제외기준에 의하여 선발되었고 최종적으로 임상연구를 마친 지원자는 66명이었다. 지원자들은 무작위로 온침군과 침군 중에 할당이 되었다. 실험군(온침)에 속한 38명은 온침시술을, 대조군(침)에 속한 38명은 침시술을 받았으며, 8주 동안 총 16회의 시술을 환측의 무릎에 시행하였다. 주된 평가척도는 Western Ontario and McMaster Universities Osteoarthritis Index(WOMAC)이었고, 부수적 평가척도는 physical health score based on the 36-Item Short-Form Health Survey(SF-36), Patient Global Assessment이었다. 결과 : 실험군이 대조군에 비해서 WOMAC의 pain, function, total score와 Patient Global Assessment에서 월등한 감소를 나타내었으나 SF-36에서는 유의한 변화가 없었다. 결론 : 이번 연구의 결과를 통해 온침이 침에 비하여 퇴행성 슬관절염 환자의 통증 감소와 기능개선에 유의성있게 효과가 있음을 확인하였다.

• 한국노년학
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• 제36권3호
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• pp.595-609
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• 2016

이 연구의 목적은 지역사회기반의 자기관리지지중재가 골관절염 의료급여수급자의 환자활력, 관절유연성 및 건강 관련 삶의 질에 미치는 단기효과를 확인하기 위함이었다. 연구 설계는 자기관리지지중재의 효과를 검증하기 위하여 무작위 대조군 전후설계를 활용하였으며, 이 연구는 자기주도적 관절염질병관리 역량강화연구의 일부이다. 연구대상은 일 지역 고위험군 의료급여수급자 중에서 60명의 골관절염환자를 대상으로 실험군(n=30)과 대조군(n=30)에 무작위 할당하였다. 8회기로 구성된 자기관리지지중재는 대상자 중심의 케어를 전략으로 인지 정서 행위기술을 활용하였으며, 교육 훈련된 의료급여관리사에 의하여 제공되었다. 연구도구는 구조화된 설문지, 관절각도기 및 줄자를 활용하였다. 자료 분석방법은 기술적 통계와 ${\chi}^2-test$, Fisher's exact test, t-test, ANCOVA를 활용하였다. 실험군은 대조군에 비하여 자기관리를 위한 환자활력, 관절유연성이 유의하게 증가되었으나 건강 관련 삶의 질 수준은 유의한 차이가 없었다. 향후에는 자기관리지지중재에 대한 장기(9 and 12-month follow up) 효과가 제시될 필요가 있다.

• Journal of Microbiology and Biotechnology
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• 제31권10호
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• pp.1401-1408
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• 2021

This study examined whether the oral administration of low-molecular-weight collagen peptide (LMCP) containing 3% Gly-Pro-Hyp with >15% tripeptide (Gly-X-Y) content could ameliorate osteoarthritis (OA) progression using a rabbit anterior cruciate ligament transection (ACLT) model of induced OA and chondrocytes isolated from a patient with OA. Oral LMCP administration (100 or 200 mg/kg/day) for 12 weeks ameliorated cartilage damage and reduced the loss of proteoglycan compared to the findings in the ACLT control group, resulting in dose-dependent (p < 0.05) improvements of the OARSI score in hematoxylin & eosin (H&E) and Safranin O staining. In micro-computed tomography analysis, LMCP also significantly (p < 0.05) suppressed the deterioration of the microstructure in tibial subchondral bone during OA progression. The elevation of IL-1β and IL-6 concentrations in synovial fluid following OA induction was dose-dependently (p < 0.05) reduced by LMCP treatment. Furthermore, immunohistochemistry illustrated that LMCP significantly (p < 0.05) upregulated type II collagen and downregulated matrix metalloproteinase-13 in cartilage tissue. Consistent with the in vivo results, LMCP significantly (p < 0.05) increased the mRNA expression of COL2A1 and ACAN in chondrocytes isolated from a patient with OA regardless of the conditions for IL-1β induction. These findings suggest that LMCP has potential as a therapeutic treatment for OA that stimulates cartilage regeneration.

• The Korean Journal of Pain
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• 제36권2호
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• pp.195-207
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• 2023

Background: This study aimed to compare the effectiveness of the pericapsular nerve group (PENG) block and intra-articular injection (IAI) of steroid-bupivacaine in the treatment of hip osteoarthritis (OA). Methods: After randomization, patients received either a PENG block or IAI under ultrasound-guidance. Clinical evaluations were recorded at baseline, day 1, and weeks 1, 4, and 8 post-intervention. The numerical rating scale (NRS), Western Ontario and McMaster Universities Arthritis Index (WOMAC), Harris Hip Scale (HHS) scores, pain medication use determined by a quantitative analgesic questionnaire, and patient satisfaction were evaluated. Results: Sixty patients were included in this study. NRS scores improved significantly for both groups during the follow-up compared to pretreatment (P < 0.001), with better pain scores for the PENG group (P < 0.001) at day 1 with larger effect size (Cohen's d = 4.62), and IAI group at 4 (Cohen's d = 5.15) and 8 (Cohen's d = 4.33) weeks (P < 0.001). There was no significant difference in pain medication consumption (P = 0.499) and patient satisfaction (P = 0.138) between groups. Patients in the IAI group experienced significant improvement in HHS (Cohen's d = 2.16, P = 0.007) and WOMAC (Cohen's d = 1.02, P = 0.036) scores at 8 weeks compared to the PENG group. Conclusions: The ultrasound-guided PENG block provides effective pain relief which improves functionality and quality of life in hip OA patients up to 2 months. The PENG block can be considered an easy, safe, and useful alternative treatment modality for hip OA.

• Journal of Acupuncture Research
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• 제35권3호
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• pp.145-148
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• 2018

The purpose of this case study was to use Korean medicine to treat posterior cruciate ligament avulsion fracture. The patient suffered left knee pain resulting from an avulsion fracture and was hospitalized for 59 days and treated with acupuncture and traditional Korean medicine. The effect of the treatment was evaluated using the Numerical Rate Scale, the Western Ontario and McMaster universities Osteoarthritis Index, and the European Quality of Life Five Dimensions. Following treatment of the pain in the left knee, scores for Numerical Rate Scale, Western Ontario and McMaster universities Osteoarthritis Index, and European Quality of Life Five Dimensions were improved. This study suggested that Korean Medicine could be an effective treatment for posterior cruciate ligament avulsion fractures. Further studies are needed to substantiate this conclusion.

• 근관절건강학회지
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• 제17권2호
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• pp.212-221
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• 2010

Purpose: The purpose of this study was to determine the effects of music therapy (Jang-Gu) on depression, stress, pain and body discomfort in women with osteoarthritis. Methods: The study is designed using one group pretest-posttest experimental design. 31 arthritis patients, the subjects of the group participated in the music therapy program. The program was provided for 12 weeks (two times per week). The questionnaires were used to measure the outcome variables before and after the program. Data were analyzed with the SPSS 17.0 using descriptive statistics, paired t-test. Results: Depression, Stress, Pain did not decrease. But body discomfort decreased (p=0.001). Conclusion: Therefore this program was effective in body discomfort and can be a community based self-help management program for arthritis patient.

• Journal of Oral Medicine and Pain
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• 제32권1호
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• pp.121-128
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• 2007

환자가 내원하여 급성 부정교합을 호소한다면 치과의사는 여러가지 가능성에 대해서 생각해 볼 수 있다. 급성 부정교합은 주로 치아와 치아주변조직과 관련된 문제로 인해 발생할 수 있지만, 턱관절장애와 관련된 문제로 인해서도 발생할 수 있기에 임상가로 하여금 진단 및 관리에 어려움을 준다. 이에 저자는 외익돌근경련, 턱관절 원판후조직염 및 골관절염으로 발생한 급성 부정교합 환자를 경험하였기에 그 진단 및 치료과정을 보고하고자 한다.

• Journal of Chest Surgery
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• 제7권1호
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• pp.79-84
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• 1974

Acute suppurative pericarditis is recognized as a rare disease since development of antibiotics but therapeutically as an important one. To our knowledge, acute suppurative pericarditis alone has not been reported previously in Korea. In this paper, we report 5 cases of acute suppurative pericarditis which were experienced during the period between January 1959 and December 1973. The patients ranged in age from 9 months to 59 years at the time of admission. Four of 5 patients were male and one female. Acute suppurative pericarditis is usually associated with pneumonia, empyema, sepsis, osteoarthritis, lung abscess, cholecystitis or tonsillitis. In our series, pneumonia was the most common associated disease. One patient had osteoarthritis. Pleural effusions were observed in three of the 5 patients. Staphylococcus aureus was cultured from pericardial fluid in 4 patients and also cultured from both pericardial and synovial fluid in one. Three of the 5 patients had cardiac tamponade and one patient required prompt pericardiocentesis. 3 of the 5 patients were treated with antibiotics and pericardiostomy, one with antibiotics and pericardiocentesis, and one with antibiotics and saline irrigation through drainage sinus from the pericardial sac. Four of the five patients were recovered without pericardial constriction. One was discharged with poor condition. In this instance, follow-up study couldn`t be made.