• 한국식품저장유통학회지
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• 제22권1호
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• pp.154-157
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• 2015

신선편이용 절단배추의 선도유지 및 갈변 방지 목적으로 질소 치환 및 세라믹 칼날에 의한 절단 효과를 조사하였다. 저장 5일 이후부터 대조구에 비하여 NC 처리구의 중량변화와 갈변도가 적게 나타났다. 질소 치환과 세라믹 칼날의 사용에 의한 절단 공정의 개선이 절단채소의 선도 유지와 갈변 방지에 효과가 있을 것으로 생각된다.

• Clinical and Experimental Otorhinolaryngology
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• 제11권4호
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• pp.259-266
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• 2018

Objectives. Carcinomas of the external auditory canal (EAC) are rare, and management remains challenging. Previous studies seeking prognostic factors for EAC cancers included cancers other than carcinomas. In this study, we analyzed the treatment outcomes of, prognostic factors for, and survival rates associated with specifically squamous cell carcinoma (SCC) of the EAC. Methods. A retrospective review of 26 consecutive patients diagnosed with SCCs of the EAC in a 10-year period was performed in terms of clinical presentation, stage, choice of surgical procedure, and adjunct therapy. Overall survival (OS) and recurrence-free survival (RFS) were calculated and univariate analysis of prognostic factors was performed. Results. The median age of the 26 patients with SCCs of the EAC was 63 years (range, 40 to 72 years), and 16 males and 10 females were included. According to the modified University of Pittsburgh staging system, the T stages were T1 in 11, T2 in six, T3 in four, and T4 in five cases. The surgical procedures employed were wide excision in three cases, lateral temporal bone resection (LTBR) in 17, and extended LTBR in four, and subtotal temporal bone resection in two. Two patients underwent neoadjuvant chemotherapy, and two underwent adjuvant chemotherapy. One patient received preoperative radiation therapy, and eleven received postoperative radiation therapy. Of the possibly prognostic factors examined, advanced preoperative T stage and advanced overall stage were significant predictors of RFS, but not of OS. Conclusion. The advanced T stage and overall stage were associated with decreased survival after surgical treatment in patients with SCC of the EAC, highlighting the importance of clinical vigilance and early detection.

• Radiation Oncology Journal
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• 제30권4호
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• pp.205-212
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• 2012

Purpose: To evaluate the effect of pelvic radiotherapy (RT) in patients with stage IV rectal cancer treated with resection of primary tumor with or without metastasectomy. Materials and Methods: Medical records of 112 patients with stage IV rectal cancer treated with resection of primary tumor between 1990 and 2011 were retrospectively reviewed. Fifty-nine patients received synchronous or staged metastasectomy whereas fifty-three patients did not. Twenty-six patients received pelvic radiotherapy. Results: Median overall survival (OS), locoregional recurrence-free survival (LRFS), and progression-free survival (PFS) of all patients was 27, 70, and 11 months, respectively. Pathologic T (pT), N (pN) classification and complete metastasectomy were statistically significant factors in OS (p = 0.040, 0.020, and 0.002, respectively). RT did not improve OS or LRFS. There were no significant factors in LRFS. pT and pN classification were also significant prognostic factors in PFS (p = 0.010 and p = 0.033, respectively). In the subgroup analysis, RT improved LRFS in patients with pT4 disease (p = 0.026). The locoregional failure rate of the RT group and the non-RT group were 23.1% and 33.7%, showing no difference in the failure pattern of both groups (p = 0.260). Conclusion: Postoperative pelvic RT did not improve LRFS of all metastatic rectal cancer patients; however, it can be recommended to patients with pT4 disease. A complete resection of metastatic masses should be performed if possible.

• 생약학회지
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• 제24권2호
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• pp.140-152
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• 1993

This study was attempted to investigate the effect of Ganoderma lucidum extract on digestive system in experimental animals. Ganoderma lucidum water extract (GWE) was found to be promoted the charcol transport rate in the small intestine of mice. GWE exhibited the augmentation of spontaneus movement(motility) and contractile response(tension) in the ileum and colon strips of rabbit, and these action were inhibited by atropine. GWE given intraduodenaly(i.d.) exhibited the significant increase of gastric acid secretion in pylorus-ligated rats. GWE inhibited the formation of some experimental gastric ulcers(pylorus ligation ulcer i.d., indomethacin-induced ulcer p.o., i.d. and aspirin-induced ulcer p.o.) in rats, which are considered to relate to a protective action. GWE and EtOH extract(water soluble phase) were remarkably increase of bile excretion, when administration of i.d., intravenation(i.v.) and per os (p.o.) compared with normal-control group. GWE was observed antibacterial activity aginst several intestinal microoganisms and others bacteria in vitro test.

• 한국정보통신학회논문지
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• 제15권1호
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• pp.227-232
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• 2011

현재 무선센서노드 기반의 헬스케어 모니터링 시스템이 활발히 연구되고 있다. 하지만 생체신호의 모니터링을 위한 전체 데이터의 전달은 무선센서네트워크 내의 데이터 트래픽과 에너지 소모가 증가하게 된다. 본 연구에서는 경량의 전처리 과정 및 알고리즘을 통해 ECG신호에서 의미있는 파라미터만을 검출하여 전송하였다. 본 연구에서는 정상적인 ECG에서 무선센서노드에서 R피크, RR간격을 검출할 수 있는 TinyOS 기반 어플리케이션을 구현하였으며 결과로 dECG, R피크, RR간격, HRV를 그래프로 확인 할 수 있었다. 따라서 본 연구를 이용하면 ECG신호 전체 데이터가 아닌 주요 정보만을 보냄으로서 에너지 소모, 데이터량을 줄일 수 있다.

• 한국수의병리학회:학술대회논문집
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• 한국수의병리학회 2003년도 추계학술대회초록집
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• pp.57-57
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• 2003

Canine osteosarcoma is the most common bone tumor in dog and is characterized by locally aggressive and highly metastatic behavior [1]. Generally malignant tumors meta stasizes by hematogenious routes and rarely through lymphatic pathway, and the lymph node is uncommon metastatic site [2,3]. In this case, the patient has a typical osteosarcoma on his proximal humerus that is the common form of canine OS [4,5]. But the tumor made severe metastatic form to the right axillary lymph node which has a diffuse contribution of osteoid matrix all of the tissue. So, the case is the valuable topic for evaluate the correlation of metastasis to lymph node which is near the primary tumor region and pro gnosis of canine appendicular osteosarcoma. (omitted)

• 마케팅과학연구
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• 제5권
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• pp.43-56
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• 2000

본 연구는 Dienhart et al.(1993)이 제시한 조직지원, 고객초점, 압박상황하에서의 서비스로 구성된 레스토랑 종업원의 서비스지향성을 고객초점과 압박상황하에서의 서비스로 재정의하고, 조직지원을 종업원의 서비스지향성을 촉진하는 요인으로 제시하였다. 그리고 조직지원과 직무만족, 직무안정성의 상호작용이 레스토랑 종업원의 서비스지향성이 어떤 영향을 미치는가를 분석하였다. 분석 결과, 본 연구에서 레스토랑 종업원의 서비스지향성 구성요소로 제시한 압박상황에서의 서비스는 변수의 내적 일관성이 매우 낮게 나타나 제외되고 고객초점만이 종업원의 서비스지향성을 구성하는 것으로 나타나 압박상황하에서의 서비스 항목에 대한 신뢰성 검토가 추후 연구에서 있어야 할 것으로 나타났다. 그리고 조직지원, 직무만족, 조직지원과 직무만족의 상호작용이 고객초점에 미치는 영향을 분석한 결과, 조직지원은 정(+), 직무만족은 부(-)의 방향으로 영향을 미치는 것으로 나타났으나 조직지원과 직무만족의 상호작용변수를 추가한 분석에서는 상호작용(OS ${\times}$JS)이 정(+)의 유의적인 영향을 미치는 것으로 나타났다. 또한 조직지원, 직무안정성, 조직지원과 직무안정성의 상호작용이 고객초점에 미치는 영향을 분석한 결과, 조직지원과 직무안정성은 정(+)의 방향으로 영향을 미치는 것으로 나타났으나, 조직지원과 직무만족의 상호작용변수를 추가한 분석에서는 두 변수 모두 영향을 주지 않았으며 상호작용 변수만 정(+)의 유의적인 영향을 미치는 것으로 나타났다.

• Journal of Trauma and Injury
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• 제28권2호
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• pp.83-86
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• 2015

Central venous cannulation is one of the most commonly performed procedures for critically ill patients in the emergency room. Serious complications like a rupture of subclavian artery may occur during this procedure. We report a case of successful stent graft deployment for iatrogenic ruptured subclavian artery after attempted right subclavian vein catheterization in a 31 year-old female patient with hypovolemic shock due to cervical os laceration during vaginal delivery.

• 인터넷정보학회논문지
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• 제9권2호
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• pp.1-13
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• 2008

최근 이동사무환경에 대한 관심이 증대되고 있다. 이를 위한 '유비쿼터스 이동사무환경 시스템'의 메신저 시스템은 기존 메신저 프로토콜에서 지원하지 않았던 파일 요청, 사무환경 전송/ 요청 / 브로드캐스팅 등 이동 사무환경 메신저 시스템을 위한 여러 가지 새로운 개념들이 필요하다. 본 논문은 이러한 이동사무환경 메신저에 맞는 새로운 프로토콜을 설계하였으며, 기존의 프로토콜과의 차이점을 분석하였다. 또한 MOE-MP에 최적화된 서버를 구현하고 이에 대한 효율성 분석을 수행하였다. 새롭게 설계한 MOE-MP는 XMPP의 기본적인 프로토콜을 사용하였고, 이동사무환경에 맞도록 확장하였다.

• Genomics & Informatics
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• 제12권4호
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• pp.247-253
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• 2014

Osteosarcoma is the most common primary bone tumor, generally affecting young people. While the etiology of osteosarcoma has been largely unknown, recent studies have suggested that cyclooxygenase-2 (COX-2) plays a critical role in the proliferation, migration, and invasion of osteosarcoma cells. To understand the mechanism of action of COX-2 in the pathogenesis of osteosarcoma, we compared gene expression patterns between three stable COX-2-overexpressing cell lines and three control cell lines derived from U2OS human osteosarcoma cells. The data showed that 56 genes were upregulated, whereas 20 genes were downregulated, in COX-2-overexpressed cell lines, with an average fold-change > 1.5. Among the upregulated genes, COL1A1, COL5A2, FBN1, HOXD10, RUNX2, and TRAPPC2 are involved in bone and skeletal system development, while DDR2, RAC2, RUNX2, and TSPAN31 are involved in the positive regulation of cell proliferation. Among the downregulated genes, HIST1H1D, HIST1H2AI, HIST1H3H, and HIST1H4C are involved in nucleosome assembly and DNA packaging. These results may provide useful information to elucidate the molecular mechanism of the COX-2-mediated malignant phenotype in osteosarcoma.