• Animal cells and systems
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• v.3 no.1
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• pp.1-7
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• 1999

Gonadotropin-releasing hormone (GnRH) was originally isolated as a hypothalamic peptide that regulates reproduction by stimulating the release of gonadotropins. Using comparative animal models has led to the discovery that GnRH has a more ancient evolutionary origin. Durinq evolution GnRH peptide underwent gene duplication and structural changes to give rise to multiple molecular forms of GnRHs. Mammalian GnRH initially considered to be the sole molecular form, is now grouped as a family of peptides along with GnRH variants determined from representatives in all classes of vertebrates. Vertebrate species including primates and humanshave more than one GnRH variant in individual brains; a unique GnRH form in the forebrain and chicken IIGnRH in the midbrain. Furthermore, several species of bony fish have three molecular variants of GnRH: salmon GnRH sea-bream GnRH and chicken II GnRH. Also, it has been shown that in addition to the olfactory placodes and the midbrain, there is a third embryonic source of GnRH neurons from the basal diencephalon in birds and fish, which might be true for other vertebrates. Therefore, comparative animal models like fish with discrete sites of expression of three molecular variants of GnRH in individual brains, could provide insight into novel functions of GnRH variants, conservation of gene regulation, and mechanisms governing reproduction in vertebrates.

• The Bulletin of The Korean Astronomical Society
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• v.37 no.2
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• pp.75.1-75.1
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• 2012

Narrow-Line Seyfert 1 galaxies are arguably the most important AGN subclass in investigating the origin of the black hole mass-galaxy stellar velocity dispersion (MBH-${\sigma}$) relation because of their high accretion rates close to the Eddington limit. Currently, it is still under discussion whether NLS1s are off from the local MBH-${\sigma}$ relation. We select a sample of 325 NLS1 at relatively low redshift (z<0.1) from the SDSS DR7 by constraining FWHM of $H{\beta}$ in the range of 800-2,200 km/s. Among them, we measured stellar velocity dispersion of 40 objects which show strong stellar absorption lines, e.g. Mg b triplet(${\sim}5175{\AA}$), Fe($5270{\AA}$). In contrast, the other 285 objects show too weak stellar absorption lines to measure velocity dispersion. Using the sample of 40 objects with stellar velocity dispersion measurements, we investigate whether NLS1s follow the same MBH-${\sigma}$ relation as normal galaxies and broad line AGNs. We also test the reliability of the width of narrow lines as a surrogate of stellar velocity dispersion by comparing directly measured stellar velocity dispersion with ${\sigma}$ inferred from [O III], [N II], [S II] line widths, respectively. We will discuss the connection between AGN activity in NLS1s and galaxy evolution based on these results.

• Journal of Microbiology and Biotechnology
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• v.26 no.6
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• pp.1109-1114
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• 2016

H3N2 canine influenza virus emerged in South Korea in 2007 and subsequently spread to China and Thailand, causing epidemic or endemic respiratory diseases in dogs. Through intermammalian species transmission, the virus has also infected cats. However, no direct evidence of significant genetic evolution has been reported since its first emergence. Here, we describe in depth the genetic and molecular characteristics of the ancestral strain (i.e., the first virus isolate from South Korea) of the H3N2 canine influenza virus currently circulating in East Asia.

• Journal of Plant Biotechnology
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• v.38 no.3
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• pp.234-240
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• 2011

The genus Paeonia belongs to the family Paeoniaceae having significant medicinal and ornamental importance. The present investigation was undertaken with an aim to understand phylogenetic relationships of three Paeonia species (P. lactiflora, P. obovata, and P. suffruticosa) that are widely distributed in China, Korea, and Japan, using nuclear ribosomal DNA (nrDNA) internal transcribed spacer (ITS) sequence and to compare the phylogeny results with investigations reported earlier using existed sequences of the same species. The size variation obtained among sequenced nrDNA ITS region was narrow and ranged from 722 to 726 bp. The highest interspecific genetic distance (GD) was found between P. lactiflora and P. suffruticosa or P. obovata. The phylogram obtained using our nrDNA ITS sequences showed non-congruence with previous hypothesis of the phylogeny between section Paeonia and section Moutan of genus Paeonia. This result was supported by the phylogenetic relations showed in the phylogram constructed with existed sequences in NCBI. The present study suggested that P. obovata belonging to section Paeonia was phylogenetically closer to P. suffruticosa representing section Moutan of genus Paeonia than P. lactiflora belonging to section Paeonia. The main reason of the paraphyly of section Paeonia is thought to be nucleotide additivity directly caused by origin hybridization. This study provides more sequence sources of genus Paeonia, and will help for further studies in intraspecies population, and their phylogentic analysis and molecular evolution.

• Journal for History of Mathematics
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• v.19 no.2
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• pp.125-140
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• 2006

In 1933, I. Schur introduced a Schur ring in connection with permutation group and regular subgroup. After then, it was studied mostly for purely group theoretical purposes. In 1970s, Klin and Poschel initiated its usage in the investigation of graphs, especially for Cayley and circulant graphs. Nowadays it is known that Schur ring is one of the best way to enumerate Cayley graphs. In this paper we study the origin of Schur ring back to 1933 and keep trace its evolution to graph theory and combinatorics.

• Korean Journal of Metals and Materials
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• v.49 no.3
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• pp.243-249
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• 2011

This study describes the feasibility of producing high-strength Al alloy sheet with a high solute content using a combined technique of twin-roll strip casting and asymmetric rolling. The Al sheet produced in this study exhibited excellent formability ($\overline{r}$ =1.0, $\Delta$r=0.16) and mechanical properties ($\sigma_{TS}$~305 MPa, $\epsilon$~33%), that, cannot be feasibly obtained via the conventional technique based on ingot casting and rolling. The structural origin of the observed properties, especially enhanced formability, was clarified by examining the evolution of textures associated with strip casting and subsequent thermo-mechanical treatments. Our evaluation of the mechanical properties and formability leads us to conclude that the combination of strip casting and asymmetric rolling is a feasible process for enhancing the formability of Al alloy sheets to the level beyond what the conventional techniques can reach.

• Publications of The Korean Astronomical Society
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• v.38 no.2
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• pp.25-36
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• 2023

Since interstellar objects like 1I/'Oumuamua and 2I/Borisov originate from exoplanetary systems, even if we do not visit the exoplanetary systems, flyby, rendezvous, and sample return missions of interstellar objects can provide clues to solve the mysteries of cosmic life phenomena such as the origin of exoplanetary systems, galactic evolution, biosignatures (or even technosignatures), and panspermia. In this paper, we review space missions for interstellar object exploration in the stage of mission design or concept study such as Project Lyra, Bridge, Comet Interceptors, and Lightcraft^TM. We also review space missions, OSIRIS-REx and NEA Scout, designed for Near Earth Asteroids(NEA) explorations, to investigate the current state of basic technologies that can be extended to explore interstellar objects in a velocity of ~ 6AU/year. One of the technologies that needs to be developed for interstellar object exploration is a spacecraft propulsion method such as solar sail, which can catch up with the fast speed of interstellar objects. If this kind of propulsion becomes practical for space explorations, interstellar object explorations will mark a new era and serve as a driving force to provide evidences of cosmic life.

• Korean Journal of Veterinary Service
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• v.46 no.1
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• pp.93-106
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• 2023

Emerging and re-emerging zoonotic viruses become critical public health, economic, societal, and cultural burdens. The Coronavirus disease-19 (COVID-19) pandemic reveals needs for effective preparedness and responsiveness against the emergence of variants and the next virus outbreak. The targeted next-generation sequencing (NGS) significantly contributes to the acquisition of viral genome sequences directly from clinical specimens. Using this advanced NGS technology, the genomic epidemiology and surveillance play a critical role in identifying of infectious source and origin, tracking of transmission chains and virus evolution, and characterizing the virulence and developing of vaccines during the outbreak. In this review, we highlight the platforms and preparation of targeted NGS for the viral genomics. We also demonstrate the application of this strategy to take advantage of the responsiveness and prevention of emerging zoonotic viruses. This article provides broad and deep insights into the preparedness and responsiveness for the next zoonotic virus outbreak.

• The Bulletin of The Korean Astronomical Society
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• v.46 no.2
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• pp.81.1-81.1
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• 2021

Stellar kinematics is a useful tool to understand the formation and evolution of young stellar systems. Here, we present a kinematic study of the HII region, NGC 821, using the Gaia Early Data Release 3. NGC 281 contains the open cluster IC 1590. This cluster has a core and a low-stellar density halo. We detect a pattern of cluster expansion from the Gaia proper motion vectors. Most stars radially escaping from the cluster are distributed in the halo. We measure the 1-dimensional velocity dispersion of stars in the core. The velocity dispersion (1 km/s) is comparable to the expected virial velocity dispersion of this cluster, and therefore the core is at a virial state. The core has an initial mass function shallower than that of the halo, which is indicative of mass segregation. However, there is no significant correlation between stellar masses and tangential velocities. This result suggests that the mass segregation has a primordial origin. On the other hand, it has been believed that the formation of young stars in NGC 281 West was triggered by feedback from massive stars in IC 1590. We investigate the ages of stars in the two regions, but the age difference between the two regions is not comparable to the timescale of the passage of an ionization front. Also, the proper motion vectors of the NGC 281 West stars relative to IC 1590 do not show any systematic receding motion from the cluster. Our results suggest that stars in NGC 281 West might have been formed spontaneously. In conclusion, the formation of NGC 281 can be understood in the context of hierarchical star formation model.

• Proceedings of the Korean Society of Crop Science Conference
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• 2022.10a
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• pp.216-216
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• 2022

The starch-branching enzymes (BEs) are responsible for synthesizing the amylopectin, which plays an important role in determining the structural and physical properties of starch granules. BE has two differently functioning isoforms (BEI and BEIIa/b) based on their difference in the chain-length pattern by the degree of polymerization (DP), which mainly contributes to the amylopectin chain length distribution in starch biosynthesis. In this study, we investigated functional haplotypes and evolutionary analyses of SBE1 in 374 rice accessions (320 Korean bred and 54 wild). The analyses were performed based on the classified subpopulations. Haplotype analysis generates a total of 8 haplotypes, of which only four haplotypes were functional carrying four functional SNPs in four different exons of SBE1 on chromosome 6. Nucleotide diversity analysis showed a highest pi-value in aromatic group (0.0029), while the lowest diversity value was in temperate japonica (0.0002), indicating the signal of this gene evolution origin. Different directional selections could be estimated by negative Tajima's D value of temperate japonica (-1.1285) and positive Tajima's D value of tropical japonica (0.9456), where the selective sweeps were undergone by both positive purifying and balancing selections. Phylogenetic analysis indicates a closer relationship of the wild with most of the cultivated subgroups indicating a common ancestor for SBE1 gene. FST-values indicate distant genetic relationships of temperate japonica from all other classified groups. PCA and population structure analysis show an admixed structure of wild and cultivated subpopulations in some proportions.