• The Journal of Korean Institute of Communications and Information Sciences
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• v.35 no.7C
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• pp.634-641
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• 2010

End Stage Renal Disease resulting from complications of the 4 top causes of death including diabetes and hyperpiesia becomes one of the major social problems these days in the context that this disease unaffordably increases the medical cost and decreases the quality of life. For a kidney disease, it is hard to diagnose, cure and recover as there are few subjective symptoms. Therefore, the prevention is very important. In this paper, we propose a method, which checks the abnormal state of the kidney, using the patient's face color and gloss which is employed for diagnosis in the oriental medicine. This method composes of two processes. The first is to acquire the patient's face data applying a polarizing filter and the next is to analyse relations between kidney disease and this data.

• Korean Journal of Veterinary Research
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• v.30 no.2
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• pp.129-143
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• 1990

In the present paper, the distribution, relative frequences and cell types of endocrine cells in the gastrointestinal tract of the frog (Rana dybowskii) during the hibernating and the active phase were examined by light and electron microscopy. The results obtained are summarized as follow: The reactive cells for Grimelius were frequently found in the gastrointestinal tract, whereas the reactive cells for Hellman-$Hellerstr{\hat{o}}m$ were found numerous in the fundus and pylorus of stomach, a few in the duodenum and lower small intestine, and very few in the rectum during both phases. No reactive cells for Masson-Fontana were found in the gastrointestinal tract during both phases. Elecron microscopically, 4 types of endocrine cells in the fundus of the stomach, 3 types in the pylorus of the stomach and duodenum, and 1 type in the lower small intestine and rectum, respectively, were identified during the hibernating phase. In the active phase, 3 types of endocrine cell in the fundus of the stomach, 2 types in the pylorus of the stomach and duodenum, and 1 type in the lower small intestine and rectum were observed, respectively. In the hibernating phase, more cytoplasmic granules and various types of endocrine cells were generally found than in the active phase.

• Journal of Korean Academy of Nursing
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• v.38 no.3
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• pp.445-453
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• 2008

Purpose: This paper analyzed the historical origins of the Qi concept and assesses its possible contribution to the development of complementary therapy and new nursing practices. Methods: In order to clarify the Qi concept measure its theoretical/clinical potentials, this study analyzed both historical data and experimental research that adopt and apply the concept. These include modern/contemporary research measuring its effects in promoting mental and physical health. Using the method of cross-cultural comparison, this study analyzed diverse approaches to the Qi concept and sought to find common features among the approaches. Results: A historical, cross-cultural analysis revealed several fundamental similarities between Qi theories that have developed in the east and the holistic concepts that have evolved in the western traditions. Especially, the analysis of the more recent research on the Qi concept shows ample possibilities of its future contributions to the development of new diagnostic applications and the promotion of overall human health. Conclusion: The historical study of the Qi concept found some key common factors in the diverse philosophical traditions in the east and the west. Considering the growing popularity of complementary therapy among health professionals and the general public, the Qi concept and its clinical applications are expected to promote human health. In this context, this research contributes to developing new nursing practices based on the concept by clarifying its philosophical origins and theoretical backgrounds.

• Proceedings of the IEEK Conference
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• 2001.06e
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• pp.69-72
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• 2001

In this paper, we study about a acupuncture point and a non-acupuncture point resistance characteristics for acupuncture research. For this study, we devised resistance variation measurement system. This system is consist of 4-channel skin resistance measuring parts, filters, 12bit A/D convertor, 8051 micro-controller, and personal computer The developed system insert a low current to skin and obtains voltages from standard resistor that is convected to measurement circuit in series. The obtained voltage is converted to 12bit digital signal. Therefore the converted signal is changed to skin resistance by calculation in the personal computer. As the results of experiment, the resistance of acupuncture point and non-acupuncture point are different from each other. The acupuncture point has very fast current flows than the other non- acupuncture point.

• Journal of Korean Medical classics
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• v.32 no.4
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• pp.91-107
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• 2019

Objectives : The purpose of this paper is to study how medical experts understood 'Specially Selecting Yangming' for clinical application. Methods : After collecting medical texts related to 'Specially Selecting Yangming', its meaning and clinical application were examined thoroughly. Results : 1. The meaning of 'Specially Selecting Yangming' was identified in different ways according to the meaning of 'Yangming.' It was perceived as Stomach, Yangming meridian, Stomach meridian of Foot Yangming, Spleen and Stomach, Intestine and Stomach by medical experts. 2. Chen Wu-ze and Liu Wan-su understood Wei disease as a form of consumption, and regarded 'Specially Selecting Yangming' as tonifying Yangming while Zhang Zi-he put emphasis on Communicating Stomach Qi(胃氣) through vomiting or purgation. Sun Yi-kui insisted on applying it as a precaution. 3. Li Dong-yuan emphasized the cause of Wei disease to be Damp-Heat in the Summer and suggested Qingshuyiqitang and Qingzaotang as remedy. 4. Zhu Zhen-heng's Purging the South and Reinforcing the North is a more fundamental way of treating Wei disease by stimulating the Water-Fire Axis. Conclusions : Through a diachronic study of 'Specially Selecting Yangming' and its remedy, most medical experts regarded 'Specially Selecting Yangming' as tonifying Yangming, but tonifying Liver and Kidney was thought to be a more fundamental treatment.

• Archives of Pharmacal Research
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• v.27 no.7
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• pp.742-750
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• 2004

This paper for the first time reports the isolation of 5 compounds from Phellinus linteus. A sphingolipid (1) and two tyrosinase inhibitory compounds (2, 3) along with two carboxylic acids (4, 5), were isolated from the fruiting body of Phellinus linteus (Berk ＆ Curt) Aoshima. The structure of compound 1 was identified as 1-O-$\beta$-D-glucopyranosyl-(2S, 3R, 4E, 8E)-2-[(2R)-2-hydroxyhexadecanoylamino]-9-methyl-4,8-octadecadiene-1,3-diol, known as cerebroside B, based on spectroscopic methods such as 1D and 2D NMR as well as by acid hydrolysis. Compounds 2-5 were identified as protocatechualdehyde (2), 5-hydroxymethyl-2-furaldehyde (HMF) (3), succinic acid (4), and fumaric acid (5) based on the spectroscopic evidence. Compounds 2 and 3 inhibited the oxidation of L-tyrosine catalyzed by mushroom tyrosinase with an $IC_{50}$ of 0.40 and 90.8 $\mu\textrm{g}$/mL, respectively. The inhibitory kinetics, which were analyzed by the Lineweaver-Burk plots, were found to be competitive and noncompetitive inhibitors with a $K_{j}$ of 1.1 $\mu\textrm{m}$ and 1.4 mM, respectively.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.9
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• pp.269-282
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• 2020

This paper presents the scientific basis for the significance and physiological activity of gongyang as tributes, focusing on the four summer fruits, i.e., grapes, watermelons, oriental melons, and dragon fruits, which were used as one of the yukbeopgongyang in Yeongsanjae's thorough literature review (yeongsanjae and 2010.3~2020.2 published fruit research). As a result of the study, the fruit is not obtained from fruit trees, but from enlightenment. Chemically, the fruit had a high content of antioxidants, such as polyphenol and flavonoid. The fruit had excellent DPPH and ABTS+ radical scavenging activities and reducing power. The skin of the fruits, the non-edible part, had higher physiological activity than the flesh, the edible part. Therefore, further studies on the physiological activity in each part of dragon fruit and regarding how to ingest and utilize the peel of the four fruits need to be conducted.

• The Journal of Korean Medical History
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• v.17 no.2
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• pp.111-127
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• 2004

This paper is mainly on the rsearch of the prescriptions of "Sanbeon-bang(刪 繁方)". For the research of prescription, investigated "Sanbeon-bang" from the side of symptoms of a disease, number of drugstuffs, table of contents, drugstuffs and acupuncture and moxibustion. With these investigation, made out a few tables, and with these tables made an attempt to understand the whole prescriptions of "Sanbeon-bang". "Sanbeon-bang" is of rich contents in internal medicine. Among internal medicine, related to Oro-Yukgeuk-Chilsang(五勞-六極-七傷) was most abundant. So we can guess "Sanbeon-bang" was a medical book specialized in exhaustion syndromes. It also deals with the Samcho-syndromes, as investigate from medical comments, has the perfect system of prescription in relative. From the investigation of the combination of drugstuffs, ascertained that, the number of simple prescription composed of one drugstuff was 38, combinational prescription composed of two drugstuffs was 9, minor prescription composed of three to five drugstuffs was 47, midum prescription composed of six to ten drugstuffs was 95, major prescription composed of eleven to twenty drugstuffs was 45, and mixed prescription composed over twenty drugstuffs was 1. Mentionable unique prescriptions in internal use were the forms of keeping in mouth. In external use they were fumigants, suppositories, powdered medicines, spraying the granular medication into the nasal cavity and eyedrops. And were abundant in soft extract(ointment) and plaster. In addition, there were the recordings of 18 types of cellulitis, types of incurable cellulitis and curing an illness by a charm. By the way, when comparing "Sanbeon-bang" with "Cheongeum-bang", all of which was quoted a lot in "Oedaebiyo-bang", "Cheongeum-bang" rather took medical comments of "Sanbeon-bang" than prescription. Although there were some prescriptons in "Sanbeon-bang" at the same category, "Cheongeum-bang" took another prescriptions which are more complexed than those of "Sanbeon-bang". In the same way, when comparing "Cheongeum-bang" with "Sonjinin-Cheongeum-bang(孫眞人千金方)", which didn't go through the correction of GyojeongUiseoguk of Bug-Song goverment, "Cheongeum-bang" often didn't take the prescriptions of "Sonjinin-Cheongeum-bang". Hence we can guess, "Cheongeumyo-bang" may have added a lot of prescriptions when undergoing the correction of of GyojeongUiseoguk. The total number of species of drugstuffs in "Sanbeon-bang" from the investigation was 284. The plant drugs were 208 species, the animal were 31 species, the minerals were 19 species and the other were 26 species. The prescriptions related to acupuncture and moxibustion in "Sanbeon-bang" were only moxibustional prescriptions. Which appeared one time per exhaustion and steaming of bone syndrome, Oro-Yukgeuk-Chilsang and Samcho syndrome. Appeared six times in muscle syndromes. But I cannot imagine the original form of acupuncture and moxibustion in "Sanbeon-bang" for deficiency of data.

• Korean Journal of Acupuncture
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• v.26 no.2
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• pp.15-25
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• 2009

Objective: This paper aimed to understand influences on EEG conducting acupuncture stimulation, by comparing the changes in the acupoints on the body before and after normal people are treated with acupuncture at PC9 and TE3, which are referred to as Wood points(木穴), and PC5 and TE1, which are referred to as the Metal points(金穴) among the five shu points of Yin pericardium Meridian and Yang Triple Energizer Meridian. Methods: The study was performed on 30 healthy female volunteers in their 20's. EEG was measured for 5 minutes before acupuncture stimulation was conducted on PC9, TE3, PC5 and TE1. During 20 minutes of acupuncture treatment, the same items were continuously measured to find out whether there were any changes in them, and they were measured for 5 minutes after removing the acupuncture needles in order to implement a comparative analysis. Results: Comparision of EEG data before and after the treatment at PC9 shows no significant differences in all wave. Compared with the pre-acupuncture period at TE3, $\delta-\theta$ wave decreased significantly (P<0.05) during the acupuncture stimulation periods. Compared with the pre-acupuncture period at PC5, $\delta-\theta$ wave and high $\alpha$ wave increased significantly (P<0.05) during the acupuncture stimulation periods. And Mid $\beta$ wave and high $\beta$ wave decreased significantly (P<0.05) during the acupuncture periods and the post acupuncture periods. Compared with the Pre-acupuncture period at TE1, $\delta-\theta$ wave, $\theta$ wave and high $\alpha$ wave increased significantly (P<0.05) during the acupuncture stimulation periods. And Low $\beta$ wave decreased significantly (P<0.05) during the acupuncture periods. Conclusion: When acupuncture stimulation was performed on PC9 and TE3, referred to as the "Wood points", brain waves were stabled, while when acupuncture was performed on PC5 and TE1, called the "Metal points", a brain was waked. From the findings of this study, we hypothesize that the wood properties, from which growing starts in all things, are related with fast waves of EEG, and the metal properties, which stabilize and converge in all things, are related with slow waves of EEG.

• Journal of Korean Medical classics
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• v.31 no.4
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• pp.1-16
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• 2018

Objectives : The paper studies the epistemology of Wind Herbs, its origin, its drug category and medicinal property, attempted to understand Lidongyuan's framework of mechanism of internal damage and treatment principle, and why he used it from his viewpoint. Methods : His suggestion was based on this treatment of internal damage suing wind herbs. Therefore, it cannot be viewed as a simple herbological concept. It rather displays the characteristics of medication based on clinical pathology. Therefore, wind herb should be comprehensively understood from the understanding of the mechanism of internal damage. That is why the paper studied around Piweilun, where Lidongyuan's concept on internal damage is established with finality. Additionally, the paper also referred to Wanghaogu's Tangyenbencao, a text that comprehensibly assembles the authors of Zhangyuans, Yixuqiyan's and Yishuixuepi's knowledge o herbology. Results : The origin of wind herb is 'herbs that uses the unique nature of wind in treatment of disease.' Medication unfolds yang qi, and this signifies the Shengyang function. This means that it starts from the lower energizer yin aspect, which is the beginning point of yang qi, and unfolds to the whole body through upbearing and effusion. Instead of producing yang qi directly similar to pungent, sweet and warm formula, however, it contributes to the achievement of the final purpose of the way of Shengyang through forming a ascending mechanism in the whole body via yin aspect's yang qi upbearing and effusion. Conclusions : Wind herb is within the scope of clinical herbology selected by Lidongyuan, for the purpose of achieving comprehensive clinical purposes, in order to treat internal damage. In this way, wind herb is distinguished from the application of other medicines that are limited in usage depending on Qiwei.