• 동의생리병리학회지
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• 제23권6호
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• pp.1241-1246
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• 2009

It has been suggested that Tae-Eum peoples are prone to obesity. Although extensive clinical observations have shown this tendency in Sasang Constitutional Medicine (SCM), no scientific hypothesis has been proposed to delineate its mechanism. According to SCM theory, Tae-Eum peoples have a hypoactive lung system and a hyperactive liver system. In this paper we propose a new hypothesis explaining the tendency of obesity in Tae-Eum people in the viewpoint of cell physiology. The hypoactive lung system might imply an attenuated 'respiration' at the cell/subcell level, namely mitochondrial oxygen consumption. Because a functional weakness in mitochondria energy metabolism indicates intrinsic hypo-activity in the consumption (or production) of metabolic energy, we deduced that the tendency can easily induce body weight gain via an increase in anabolism. This relation is also introduced in the graph of cellular metabolic power against body weight. To test this hypothesis, we analyzed the clinical data with 863 subjects. Statistical analysis of the data showed that Tae-Eum peoples had relatively a lower cellular metabolic power, and that the percentage of peoples with BMI>25 was significantly higher than that of the other constitutional types.

• 대한약침학회지
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• 제12권1호
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• pp.77-89
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• 2009

Objectives : Mistletoe extracts have been in use for around 85 years, predominantly in the area of cancer therapy. Today mistletoe preparations are among the most prescribed drugs in cancer medicine, thus constituting a standard biological therapy in the area of oncology. The purpose of this study is to analyze the practical implications of mistletoe cancer therapy, their clinical status, their preparation techniques and companies. Contents : Mistletoe therapy for cancer has been developed within the context of anthroposophical medicine. One major effect of mistletoe extract is that it stimulates the immune system and cancer defences. In Germany, a total of eight different mistletoe preparations are available, five developed by Anthroposophic Medicine and three evolved from research in phytotherapy. Therapy always consists of an introductory phase in order to test the patient's tolerance, find the right dosage and choose the most suitable preparation. This paper covers the background of mistletoe medical plant materials, mistletoe therapy for cancer, the anthroposophical medicine and clinical research, the practical regulation of treatment, preparation of mistletoe drugs. Result & suggestion : Mistletoe extracts are a complementary teratment of cancer, widely used in intergrative cancer care. The study of the integration of korean mistletoe extracts to oriental cancer medicine, its development and feasibility in Korea are urgently needed. The products, substances, compositions of european mistletoe drugs are very similar to those of oriental medicine theory. Applying the mistletoe cancer therapy and its preparation techniques to oriental medicine, the herbal acupuncture preparation should be modernized and korean mistletoe products are to be developed. To this end, government and herbal acupuncture society need to interact each other for the development of oriental mistletoe cancer medicine.

• 대한한방내과학회지
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• 제27권1호
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• pp.84-91
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• 2006

The importance of measurement of health-related quality of life (HRQL) cannot be overemphasized. However, efforts to implement HRQL measurement often fail because of differences in definition and insufficient information about available measures. In this paper, many available HRQL measures are reviewed, which have been designed for, or frequently used with, people with cancer in order to aid in the evaluation of effects of oriental medicine on cancer patients. A total of 28 articles were selected from three different databases. The selected articles were analyzed according to three aspects of application of the Korean version of HRQL measures, namely generic, disease specific and symptoms related instruments. Nine HRQL measures are completed with Korean validation and data collection under contact and permission of the author. However, research studies that reported data on quality of life (QOL) in cancer patients treated with oriental medicine were wholly lacking. It is recommended that further studies be performed, using methods of data collection whose validity and reliability has been confirmed.

• 사상체질의학회지
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• 제17권3호
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• pp.31-54
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• 2005

1. Objectives This paper was written in order to understand the function of acupoints as Sasang Constitution. 2. Methods Through the concept of ${\ulcorner}$Seung-Gang-Wan-Sok(升降緩束)${\lrcorner}$, we could find out the function of some acupoints as Sasang Constitution. 3. Results and Conclusions 1) Some acupoints could be classified into four groups. These four groups are corresponded with four Sasang Constitutional groups 2) This four groups are supported by the concept of ${\ulcorner}$Seung-Gang-Wan-Sok(升降緩束)${\lrcorner}$. 3) The first group is for Soeumin(少陰人). The acupoints are 'Sangwan(上脘, CV13)', 'Chungwan(中脘, CV12)', 'Hwangsu(?兪, K16)', 'chonchu(天樞, S25)' and 'Wisu(胃兪, B21)'. These acupoints all have Seung(升: elevating Gi(氣))-function in their Oriental medical effects 4) The second group is for Soyangin( 少陽人). The acupoints are 'Kichung(氣衝, S30)', 'Choksamni(足三里, S36)', 'Sangohu(上巨虛, S37)', 'Hagoho(下巨虛, S39)', 'Haegye(解谿, S41) and 'hyonjong(懸鍾, G39)'. These acupoints all have Gang(降: descending Gi(氣))-function in their Oriental medical effects. 5) The third group is for Taeumin(太陰人). The acupoints are 'Oje(魚際, L10)', ' Taeyon(太淵, L9)', 'Taedo(大都, Sp2)', 'Taebeak(太白, Sp3)' and 'Nohoe(?會, TE13)‘. These acupoints all have Wan(緩: efferenting Gi(氣))-function in their Oriental medical effects. 6) The fourth group is for Taeyangin(太陽人). The acupoints are 'Kwanwon(關元, CV4)', 'Hawan(下脘, CVlO)’ and ‘Chungjong(中庭, CVI6)’. These acupoints all have Sok(束: afferenting Gi(氣))-function in their Oriental medical effects.

• 대한예방한의학회지
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• 제6권1호
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• pp.117-128
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• 2002

Metal problems in herbal medicine are not regulate properly by law and public management around world country until this time. General people belief as safety about herbal since natural material. And almost all persons can also purchase by their-self and use by self-prescription in reality. As this result herbal medicines can always occur acute and chronic toxicity by not proper use problems, side-effect and overdose. Heavy metal toxic diseases in historical view point was big accidents that didnot forget including minamata and itai-itai in Japan. These accident's teach to us must not use toxic metal level and not include or at least Pb Hg As Cd in all kind material use and intake by people, especially herbal. Herbal contamination research is beginner state that had not many papers until nowadays. Even if this pan had some papers, it had negative result and bigger and larger than problems level because of one way research trend of not many sample case-report and screening test of dried herbal form in chiefly. Many persons have afraid and risk thinking about herbal, animal and minerals since these cause. Further research related this subject will be needed at fact of epidemiology including case-control and cohort study for more precision research affecting in short and long term intake of oriental medicines

• 대한한의학회지
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• 제27권4호
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• pp.225-232
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• 2006

Objective : To test the hypotheses that individualized traditional Korean acupuncture improves pain and disability in patients with osteoarthritis of the knee and that benefits remain after stopping treatment more so than is the case for standardized minimal acupuncture. Design : Randomized single blind controlled trial with two intervention arms (individualized traditional Korean acupuncture, standardized minimal acupuncture) of six weeks' duration and three months follow-up. Setting : Acupuncture interventions were applied by two training doctors in the Department of Acupuncture and Moxibustion in a 1000-bed hospital. Assessment of the result was performed in a university-based laboratory. Participants : 50 patients with symptoms of knee osteoarthritis as diagnosed by an orthopedist. Intervention : Individualized traditional Korean acupuncture or standardized minimal acupuncture for six weeks. Main outcome measures: Primary outcome measure was pain as measured by the visual analogue scale. Secondary measures of pain and disability included the Western Ontario and McMaster Universities (WOMAC) index, Short Form-36 (SF-36), Lequesne Functional Index (LFI) score and Korean version of Health Assessment Questionnaire (KHAQ). Discussion : This paper presents detail on the rationale, design, methods and operational aspects of the trial.

• 한국한의학연구원논문집
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• 제17권2호
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• pp.73-83
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• 2011

The first medical text in which detailed treatments of diseases by combinations of materia medica are mentioned is the "Shanghanzabinglun(傷寒雜病論)". True meaning of the combinations of materia medica used in this text lies in the fact that the efficacy of a prescription transcends that of the linear sum of each materia medica. This kind of concept regarding the composition of a prescription has come to contribute to the formation of theories in prescriptionology; However, it is difficult to analyze and interpret the meaning of each prescription separately because of differences in interpreting methods, points of view, and terminologies used by members of different academical branches. Therefore, it is desirable that one should understand a prescription as having been modified from a basic prescription, and then bring the interactions of ingredients into the picture, finally understanding the efficacy and chief virtues of the targeted prescription. Nevertheless, with the massive information of prescriptions, which exist in the format of texts, it is impossible to efficiently take advantage of prescription analyzing methods, and therefore the range of analysis extremely restricted. In order to overcomes these weaknesses, this paper suggests that object-oriented prescription database be constructed and that a search program for education and research that could facilitate an efficient access to the database be developed as well.

• 한방안이비인후피부과학회지
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• 제21권3호
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• pp.235-240
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• 2008

Objective : To carry out the oriental medicine treatment on a patient with Retinal Artery Occlusion in the left Methods : 1. Diagnosis: Fundus photography, Colored paper. 2. Treatment: Acupunture, Herbal medications. Results : It reported that oriental medicine is an effective treatment for a patient who felt a pain in eyes and hardly recognized the light. Through the treatment, the patient is steadily able to relieve the pain in eyes; to be aware of the light; and to perceive the shape of the object and it' s movement. Conclution : 1. Retinal Artery Occlusion is acute disease that vision is diminished fastly and become a blindness. 2. It belong to the cathegory of Pock Maeng(暴盲) in Oriental Medicine. 3. We could get the effective result by providing the patient with Tongkuhwalhyol-tang and Moschus.

• 대한한의학회지
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• 제32권3호
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• pp.10-17
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• 2011

Objective: To evaluate the immune-stimulatory potential of extracts of Broussonetia kazinoki Siebold (BK) on specific cellular and humoral immune responses in ovalbumin (OVA)-immunized mice. Material and Methods: C57BL/6 mice were immunized intraperitoneally with OVA/alum ($100{\mu}g/200{\mu}g$) on days 1, 8, and 15. BK (100, 300 or 1000 mg/kg) was given to mice orally for 21 days (from day 1 to day 21). At day 22, OVA-, lipopolysaccharide (LPS)- and concanavalin A (Con A)-stimulated splenocyte proliferation and OVA-specific and total antibodies were measured in plasma. Further, the effects of BK on expression of cytokine mRNA in OVA-immunized mice splenocytes were evaluated by RT-PCR analysis. Results: BK significantly enhanced OVA-, LPS-, and Con A-induced splenocyte proliferation in OVA-immunized mice (p<0.01). BK also significantly enhanced total IgM and OVA-specific IgG1 levels in plasma compared with the OVA control group. Moreover, BK up-regulated significantly the expression of mRNA level of IL-2 and IFN-${\gamma}$ in splenocytes. Conclusions: BK has immune-stimulating activity in an OVA-immunized mouse model system, enhancing the Th1 immune response. BK showed no cytotoxicity in this system, suggesting that BK may be a safe and effective adjuvant in humans.

• 사상체질의학회지
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• 제16권2호
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• pp.44-51
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• 2004

1. Objectives This paper is written for clear understanding on the concepts of 'Deep adherence of the Nature' and 'Sudden explosion of the Emotion' and for intensive comprehension of Mechanism of 'The Exterior Disease' and 'The Interior Disease' by The Nature and the Emotion. 2. Methods The study mainly based on "The exterior disease injured by the Nature, the interior disease injured by the Emotion" and deals with 'Seongmyungron, Sadanron, Hwarkchungron and Jangburon'. 3. Results and conclusions The conclusions as follows (1) Exterior Disease in each constitution breaks out by deep adherence of the Nature. Interior Disease brings out with sudden explosion of the Emotion. (2) 'Deep adherence of the Nature' is the state that the Ear, Eye, Nose, Mouth taking care of environmental frames can't work enoughly because of wrong minds on the Jaw, Breast, Umbilicus, Abdment. 'Sudden explosion of the Emotion' is the state that the Lung, Spleen, Liver, Kidney doing human affairs doesn't do appropriately for each constitution due to negative minds on the Head, Shoulder, Waist, Hip. (3) The result that the Ear, Eye, Nose, Mouth doesn't extract the clear energy from 'Jin, Go, You, Yaek sea' so they are lack of 'Shin, Qi, Hyul, Jeong' causes exterior disease in each constitution. (4) In each constitution, Interior disease results from that the Lung, Spleen, Liver, Kidney fails to bring on the clear juice from 'Lee, Mak, Hyul, Jeong sea', so shortage of 'Jin, go, You, Yaek' results in it.