• Journal of Acupuncture Research
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• 제30권3호
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• pp.141-153
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• 2013

Objectives : The study aimed to show the clinical effects of oriental medical treatments for vascular disease of spinal cord. Methods : The patients were treated using acupuncture, electroacupuncture, pharmacoacupuncture, herbal medication. And the effects for vascular disease of spinal cord have measured in ASIA scale, SCIM III. Results : Sensory score on the ASIA scale is increased 128 to 156 in case 1, 189 to 196 in case 2. Motor score on the ASIA scale isn't changed in case 1, but is increased 90 to 99 in case 2. SCIM III is improved 25 to 30 in case 2. Conclusions : From the above results, It is considered that oriental medical treatments is effective on vascular disease of spinal cord.

• 동의신경정신과학회지
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• 제20권3호
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• pp.229-236
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• 2009

Objectives : This study is designed investigate the effect of oriental medial therapy on a 63 year old female patient had Miller Fisher Syndrome with sleeplessness. Methods : We experienced a case of Miller Fisher Syndrome and treated with herbal medicine, eletro-acupuncture. The effects of treatment were measured by sleeping hour, taken measurements with a ruler(eyeball movement). Results : Whole condition (ophthalmoplegia, ataxia and so on) was improved and Oriental treatment had a good effect on sleeping hour. Conclusions : Oriental medical treatments were very effective for the patient had Miller Fisher Syndrome with sleeplessness.

• Journal of Acupuncture Research
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• 제38권3호
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• pp.205-218
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• 2021

Background: Korean medicine treatment was assessed in patients with knee osteoarthritis (OA) according to subgroups of: sex, age, cause of knee OA, body mass index, hospitalization period, history, OA compartment, phenotype, and comorbidity. Methods: A retrospective review was performed of 122 inpatients who were admitted to the Hospital of Korean Medicine for Korean medicine treatment of knee pain, and were diagnosed with knee OA based on magnetic resonance imaging findings. Analysis of patient subgroups (sex, age, cause of knee OA, body mass index, hospitalization period, history, OA compartment, phenotype, and comorbidity) was carried out and treatments including acupuncture, cupping, pharmacopuncture, herbal medicine, chuna therapy, medicinal steaming therapy, manual therapy, and extracorporeal shock wave therapy were listed. The numeric rating scale (NRS), Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), and 5-level EuroQol- 5 Dimension (EQ-5D-5L) scores were measured before and after treatment to assess the effects of treatment on pain and quality of life. Results: Seventeen males and 105 females were included in this study. Most patients were in their 60s. In the total study population, NRS, WOMAC, and EQ-5D-5L scores were improved statistically significant when comparing before and after treatment. The NRS and WOMAC scores improved statistically significant in the medial, patellofemoral, medial + patellofemoral, medial + lateral + patellofemoral compartment. Conclusion: Korean medicine treatment significantly reduced pain, stiffness, and physical dysfunction, and improved the quality of life of patients with knee OA, suggesting that it may be an effective alternative to the current conservative treatments.

• 동의생리병리학회지
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• 제16권2호
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• pp.303-310
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• 2002

Ancient Korean physicians have used several oriental herbs to cure dementia and these effects were described in the Korean herbal books. Some cognitive-enhancing oriental herbs have been widely used as a herbal medicine against dementia. However, few of studies have proved their efficacy in treatment for dementia. In the present study, we investigated the effects of herbal compounds, which are mainly consisted of Uncaria sinensis, Corydalis yanhusuo and Acorus gramineus on learning and memory in Mortis water maze task and the central cholinergic system of the rats with neurotoxic medial septum lesion. In water maze test, the animals were trained to find a platform in a fixed position during 6 days and then received a 60-s probe trial in which the platform was removed from the pool on the 7th day. Ibotanic and 192 saporin lesion of the medial septum (MS) impaired the performance of maze test and degenerated choline acetyltransferase (ChAT) in the brain, which is a marker of the central cholinergic system. Daily administrations of herbal medicine (100mg/kg, p.o.) for 21 consecutive days produced significant reversals of the neurotoxic-induced deficit in learning and memory. These treatments also reduced the loss of cholinergic immunoreactive neurons in the brain induced by neurotoxin. These results demonstrated that herbal compounds ameliorated learning and memory deficits through effects on the central nervous system, partly through effect on the acetylcholine system. Our studies suggest an evidence of these herbs as treatment of Alzheimer's disease.

• 대한예방한의학회지
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• 제15권1호
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• pp.131-143
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• 2011

Objective : The purpose of this study was survey about the recognition and demand on cooperative system between western and oriental medicine of stroke patients in National Rehabilitation Center. Methods : The participants were 205 stroke patients in the National Rehabilitation Center and investigated the recognition and demand on cooperative system between western and oriental medicine. Results : As to general characteristics of the group, 56.9% were male, 30.7% were in the 60~69 age, 24.3% of patients had an average income per month 1.0~2.0 million. In regard to disease status of patients, 53.8% were cerebral infarction, 35.8% were below 6 month in disease duration, 73.7% were none recurrence, 52.8% were hypertension as related disease, 74.5% were motor paralysis sequela. 83.2% were positive response in using oriental medicine department of National Rehabilitation Center. The most wanted therapy was acupuncture. Most of respondents expected that co-operative treatments were to be improving the cure effect for patients. And they wanted cooperative system combined evenly between western and oriental medicine, so the western doctors and the oriental doctors suggest the plan giving lots of medial benefits for patients. Conclusion : This survey showed the recognition and demand on cooperative system between western and oriental medicine of patients in National Rehabilitation Center. It is possible to realize patient's centered treatment under the stable and efficient cooperation of western and oriental medicine.

• 대한한의학회지
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• 제23권2호
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• pp.125-138
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• 2002

Learning and memory are essential requirements for every living organism in order to cope with environmental demands, and cholinergic systems are known to be involved in learning and memory. Scutellaria baicalensis (SB) and Gastrodia elata (GE) as a traditional Oriental medicine have been clinically used to treat or prevent memory deficits, including Alzheimer's disease. In the present study, we investigated the effects of SB and GE on learning and memory in the Morris water maze task and the central cholinergic system of the rats with excitotoxic medial septum lesions. In the water maze test, the animals were trained to find a platform at a fixed position over 6 days and then received a 60-s probe trial in which the platform was removed from the pool on the 7th day. Ibotenic lesion of the medial septum (MS) impaired their performance in the maze test (latency of acquisition test on the 3rd day, $27.6{\pm}$4.4 sec vs. $61.7{\pm}17.7$ sec; retention test, $7.9{\pm}1.3%$ vs. $5.7{\pm}1.0%$: sharn vs. ibotenic lesioned groups, respectively) and reduced choline acetyltransferase (ChAT) - immunoreactivity in the MS and the hippocarnpus, which is a marker for degeneration of the central cholinergic system (number of cells, $21.1{\pm}1.1$ vs. $13.2{\pm}1.3$: sham vs. ibotenic lesioned group). Daily administrations of SB (100mg/kg, p.o.) and GE (100mg/kg, p.o.) for 21 consecutive days produced significant reversals of ibotenic acid-induced deficit in learning and memory. These treatments also reduced the loss of cholinergic immunoreactivity in the MS and the hippocarnpus induced by ibotenic acid. These results demonstrated that SB and GE ameliorated learning and memory deficits through effects on the central nervous system, partly through effect on the acetylcholine system. Our studies suggest an evidence of SB and GE as treatment for Alzheimer's disease.