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A Review on Acne Treatment in Korean Medicine by Analyzing Case Studies with Herbal Medicine Treatment (국내 한약 치험례 분석을 통한 한의학적 여드름 치료법에 대한 고찰)

  • Cho, Eun-Chai;Kim, Kyu-Seok
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.31 no.4
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    • pp.65-82
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    • 2018
  • Objectives : The purpose of this study is 1) to explore the general tendency of the herbs or herbal formula for acne treatment in clinical practice 2) and to provide a basis for explaining the principles of acne treatment in Korean Medicine in order to make patients understand more easily based on pharmacological mechanism by analyzing the herbs or herbal formula using for acne treatment in clinical practice. Methods : In the domestic databases (Oriental medicine Advanced Searching Integrated System-OASIS, Korean Traditional Knowledge Portal-KTKP, National Discovery for Science Leader-NDSL, Research Information Sharing Service-RISS), we selected among the papers published using search terms related to "acne". Reports related to sasang constitutional medicine were excluded and a total of 23 papers were finally selected. Results : 29 prescriptions were retrieved from 23 papers. Chungan-tang (淸顔湯) notified formulas ranked first by Cheongsangbangpung- tang (淸上防風湯), Hwangnyeonhaedok-tang (黃連解毒湯), Dangguijakyaksan (當歸芍藥散) and Bipachungpe-eum (枇杷淸肺飮). Commonly used herbs are Forsythiae Fructus (連翹), Scutellariae Radix (黃芩), Gardeniae Fructus (梔子), Ligustici Rhizoma (川芎), and Angelicae Gigantis Radix (當歸). In most patients with inflammatory lesions or excessive flushing, exterior-releasing medicinal (解表藥) and heat-clearing medicinal (淸熱藥) were mainly prescribed for acne treatment, while in patients with acne accompanied hyperkeratinization, Excess sebum secretion, Dysmenorrhea or indigestion, qi-tonifying medicinal (補氣藥) or blood-tonifying medicinal (補血藥) were mainly used. KAGS (Korean Acne Grading System) was the most commonly used method for acne severity assessment. Conclusions : These findings suggest that the herbs or herbal formula for acne treatment in Korean Medicine is prescribed differently according to the cause and symptoms of acne in a unique way for control the whole body balance. Also, our findings could provide a basis for explaining the principles of acne treatment in Korean Medicine in order to make patients understand more easily based on pharmacological mechanism in clinical practice.

Kinematical Analysis of Handball Step Shoot according to Attack Position (공격위치에 따른 핸드볼 스텝슛의 운동학적 분석)

  • Kang, Sang-Hack
    • Korean Journal of Applied Biomechanics
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    • v.15 no.4
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    • pp.55-66
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    • 2005
  • The present study used a video analysis system to quantify the kinematical data of step shoot motion by male university handball players. From the results of analyzing dynamic variables of step shoot motion according to shooting direction were drawn conclusions as follows. 1. The height of release was proportional to the height of players, and the height of release appeared low in left-side attacks. This is probably because the left-right-throwing angle is larger in left-side attacks than that in center attacks and right-side attacks and, as a result, the throwing arm is lowered down in throwing. 2. The leftward inclination angle of the body was larger in order of right-side attacks > center attacks > left side attacks. 3. Players' throwing form was close to three quarter style in left-side attacks. In center and right-side attacks, the arm was somewhat more upright but still it was more three quarter style than overhand style. 4. The front-rear throwing angle at the moment of release was much higher in right-side attacks than in left-side ones. This is probably because the point of time for releasing the ball is usually late in right-side attacks and, as a result, the front-rear throwing angle becomes quite large. 5. The contribution of body parts on the ball speed was higher in order of the forearm > upper arm, hand > shoulder joint. 6. In players whose distance between the two legs at the moment of release, their body usually did not incline to the side much. Thus it is considered necessary to correct the right leg in their shooting motion. 7. According to the result of analyzing throwing form, the speed of the ball at the moment of leaving the hand was faster in right-side attacks than in left-side and center attacks.

Designing dam operations for better aquatic species' habitat and economic outcomes in a regulated river

  • Kang, Hyeongsik;Choi, Byungwoong
    • Journal of Korea Water Resources Association
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    • v.52 no.spc2
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    • pp.823-833
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    • 2019
  • This study presents the impact of natural flow patterns on downstream fish habitat and economic outcomes in the Dal Stream, Korea. The study reach is 3.35 km long, located downstream form the Goesan Dam. To assess such impact, this study performed physical habitat simulations. The River2D model was used for the computation of the flow and the HSI model for the habitat simulation. Two physical habitat variables, flow depth and velocity, were used. The Zacco platypus, Zacco temminckii, Coreoleuciscus splendidus, and Opsariichthys bidens were selected as the target species in the study area. Using the building block approach (BBA), the scenarios for the hydropeaking mitigation were presented. Scenario 1 and scenario 2 were proposed by using the magnitude - duration concept and averaged the hydrologic data over the each month, respectively. Simulation results indicated that the scenarios effects significantly increased by about 18.6% for the weighted usable area (WUA). In addition, hydroelectric power benefits with both scenarios were investigated. It was revealed that the change of storing and releasing water decreased by about 27% for hydroelectric power benefits. In order to increase economic benefits, the scenario was modified with the discharges corresponding to the hydropeaking condition except the flood season. As a result, the hydroelectric power benefits were almost the same, however the aquatic habitat for the target species increased by about 5%. The change of dam re-operations through natural flow patterns provides an opportunity to minimize environmental and economic benefits in order to balance water management.

Effect of Slow-release Fertilizer Levels of Rice in Different Cultural Methods (벼 재배양식에 따른 유효성 비료의 시용량이 생육과 수량에 미치는 영향)

  • 정진일;최원영;최민규;이선용
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.40 no.6
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    • pp.747-756
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    • 1995
  • To find out the optimum application method of slow-releasing fertilizer(SRF) and conventional fertilizer(CF) with different fertilization rate under two culture methods[l0-day old seedling machine transplanting(MT) and direct-sowing on dry paddy(DS)] in the south-western region(clay loam soil) of Korea, used were Chosun slow-releasing fertilizer(silicate latex coated fertilizer: N-P$_2$O$_{5}$-K$_2$O =18-12-13) and conventional fertilizer. Plant height and number of tillers with different two culture methods were higher at MT than DS in early growth. The ratio of dry weight in heading stage was higher at CF than SRF in MT than DS and especially, SRF 80% + CF 20% than SRF 100% or CF 100%. Leaf area index (LAI) in heading stage was higher at CF in MT but higher at SRF in DS than their counterparts. Chlorophyll content was higher at SRF than in CF expect for heading stage(HS), especially in DS. It was highest at HS in CF without its difference during maximum tillering stage(MTS) and panicle formation stage(PFS), while highest at PFS in SRF with tendency of gradual increase and decrease before and after PFS, respectively. Heading was delayed 2~3 days at SRF in two cultrue methods and 4~5 days at SRF in DS in comparison with CF in MT with delay of 2 days at DS compared with MT. Culm length was longer at CF in MT and at SRF in DS than their counterparts. Panicle number per m was more at SRF and in DS. Filled grain ratio was higher at CF and in MT. Yield was obtained 101 and 100% at 100% and 80% level of SRF in DS respectively, and 96% at 80% level of CF in MT, compared with conventional application method (516kg /l0a), and increased 2~4% at DS and 0~3% at MT in SRF. Yield was high in order of 100%(SRF) =80%(SRF) + 20%(CF) > 100%(SRF) + 20%(CF) > 80%(SRF) at MT and 80%(SRF) + 20%(CF) =100%(SRF) > 80%(SRF) =100%(SRF) + 20%(CF) at DS.

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Clinical Practice Guideline of Korean Medicine for Stroke : Preliminary Guideline and Recommendation (중풍환자에 대한 일차 한의임상진료 가이드라인)

  • Han, Chang-Ho
    • The Journal of Internal Korean Medicine
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    • v.33 no.4
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    • pp.347-366
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    • 2012
  • The aim of this new statement is to provide comprehensive and timely evidence-based recommendations on stroke management for clinical practitioners. Many countries are already well engaged in developing and releasing their own clinical practice guidelines, whereas Korean Medicine (KM) is still beginning. It will take time and effort to develop evidence-based guidelines and recommendations of KM or other traditional medicine because they are weak in the area of scientific evidence. The clinical practice guideline of Korean medicine for stroke was formulated through extensive review of published literature and consensus meeting of Korean medicine specialists. This project was supported by a grant of the Oriental Medicine R&D Project, the Ministry of Health and Welfare. Referring to guidelines developed in other countries, the experts in the subject tried to organize and develop guidelines and recommendations adequate for domestic medical circumstances. In December, 2008, a multi-disciplinary team called the Evidence Based Clinical Practice Guidelines Development Group (EBCPGsDG) for Stroke was organized. The writing committee was comprised of experts in internal medicine, acupuncture, rehabilitation, and Sasang constitution. Outside specialists and associated panels were invited for consultation. The scope of the guideline encompasses acupuncture, moxibustion and herbal medicine (including Korean medicine, traditional Chinese medicine, Kampo medicine) as interventions for stroke patients. It includes statements about ischemic stroke (I63), stroke not specified as hemorrhage or infarction (I64), and sequelae of cerebrovascular disease (I69) according to the International Classification of Disease (ICD). The committee subdivided the description of herbal medications into acute stroke management, subacute stroke management, post-stroke management, and secondary prevention of stroke. Guidelines on the practice of acupuncture and moxibustion were described in order for acute stroke management, subacute stroke management, chronic stroke management, and post-stroke rehabilitation. Clinicians who are working in the field of stroke care can adopt this guideline for their practice.

Differential Growth of the Reproductive Organs during the Peripubertal Period in Male Rats

  • Han, Seung Hee;Lee, Sung-Ho
    • Development and Reproduction
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    • v.17 no.4
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    • pp.469-475
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    • 2013
  • In mammals, puberty is a process of acquiring reproductive competence, triggering by activation of hypothalamic kisspeptin (KiSS)-gonadotropin releasing hormone (GnRH) neuronal circuit. During peripubertal period, not only the external genitalia but the internal reproductive organs have to be matured in response to the hormonal signals from hypothalamic-pituitary-gonadal (H-P-G) axis. In the present study, we evaluated the maturation of male rat accessory sex organs during the peripubertal period using tissue weight measurement, histological analysis and RT-PCR assay. Male rats were sacrificed at 25, 30, 35, 40, 45, 50, and 70 postnatal days (PND). The rat accessory sex organs exhibited differential growth patterns compared to those of non-reproductive organs. The growth rate of the accessory sex organs were much higher than the those of non-reproductive organs. Also, the growth spurts occurred differentially even among the accessory sex organs; the order of prepubertal organ growth spurts is testis = epididymis > seminal vesicle = prostate. Histological study revealed that the presence of sperms in seminiferous tubules and epididymal ducts at day 50, indicating the puberty onset. The number of duct and the volume of duct in epididymis and prostate were inversely correlated during the experimental period. Our RT-PCR revealed that the levels of hypothalamic GnRH transcript were increased significantly on PND 40, suggesting the activation of hypothalamic GnRH pulse-generator before puberty onset. Studies on the peripubertal male accessory sex organs will provide useful references on the growth regulation mechanism which is differentially regulated during the period in androgen-sensitive organs. The detailed references will render easier development of endocrine disruption assay.

Nutritional Effect of Carbonized Tobacco Leaf Debris Neutralized by Nitric and Phosphoric Acid on Nursery Seedlings (연초가공부산물(煙草加工副産物)의 탄화정도(炭化程度)에 따른 질산중화능력(窒酸中和能力)과 비효(肥效))

  • Lee, Yun-Hwan;Hong, Soon-Dal
    • Korean Journal of Soil Science and Fertilizer
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    • v.18 no.1
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    • pp.89-93
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    • 1985
  • In order to develop the nutrient material for growing plants, tobacco leaf debris (T.L.D) that is a residual product of cigarette processing was carbonated at about 50% of its weight and neutralized its alkalinity by nitric and phosphoric acid. This material ($T.L.D+3N-HNO_3+1N-H_3PO_4$ (10:1:1), as a consequence, contained 4.1% of nitrogen, 2.1% of phosphte, and 6.6% of potassium in value of about pH 7. It was very effective on seedling growth to apply 1 Kg of nutrient material per 110 1 of bed soil as basic dressing because of containing not only quick-acting nitrate but also slow-releasing organo-nitrogen and sufficient potassium.

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A Survey on Smoking Status and Its Related Factors for Female Students of A Women's University in Seoul (일부 여대생의 흡연실태와 그 관련요인 분석)

  • 곽정옥
    • Korean Journal of Health Education and Promotion
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    • v.12 no.2
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    • pp.120-138
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    • 1995
  • In order to find smoking status and its related factors for female students, a survey was conducted for 1,045 female students of a women's university in Seoul from 22nd of May to 18th of June, 1995. The results were as follows: 1. Of the 1,045 respondents, 7.4% of them were current smokers and 20.6% of them were ex-smokers. The rate of smoking by the major field of study was 18.5% in art and physical education, 10.6% in liberal art and social science, 1.9% in natural science, and 1.2% in medical science. The rate of smoking by the grade was 4.1% in the freshman, 5.9% in the sophomore, 10.9% in the junior, and 10.0% in the senior grade. 2. 7.2% of respondents experienced first smoking at junior high school, 16.8% at senior high school, 4.1% after high school, and 69.2% at college. 3. The major motivation to start smoking was 'curiosity'(57.9%), 'releasing stress'(21.6%), and 'temptation from friend or senior'(12.0%). 4. The first smoking place was 'entertainment place'(49.6%), 'own room'(20.5%), and 'school '(11.3%). And the first smoking companion was 'friend'(62.3%), 'alone'(19.9%), and 'senior or junior'(5.1%). 5. The average quantity of a daily smoking was 6.16±5.29 cigarettes in current smokers and 31.2% of them had experience to quit smoking at least one or more time. 6. Most of the reasons to quit smoking in ex-smoker were due to 'bad taste '(60.5%), 'health concern'(27.4%) and 'religion'(2.3%). 7. Current smoker and ex-smoker had more positive attitude for the female smoking than nonsmoker. And 76.7% of nonsmokers answered that they would not smoke in the future. 8. Most correspondents(89.8% of nonsmoker, 83.7% of ex-smoker, 80.5% of current smoker) strongly supported the antismoking movement. 9. The major information source in smoking were from 'radio, TV'(51.0%), 'newspaper, magazine'(38.8%) and 'school'(7.7%). 10. The multiple logistic regression analysis showed that the related factors for smoking status were satisfaction of home life, coffee intake, alcohol drinking, sister's smoking, girl friend's smoking, and knowledge about smoking.

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Development of Customized Trip Navigation System Using Open Government Data (공공데이터를 활용한 맞춤형 여행 네비게이션 시스템 구현)

  • Shim, Beomsoo;Lee, Hanjun;Yoo, Donghee
    • Journal of Internet Computing and Services
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    • v.17 no.1
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    • pp.15-21
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    • 2016
  • Under the flag of creative economy, Korea government is now releasing public data in order to develop or provide a range of services. In this paper, we develop a customized trip navigation system to recommend a trip itinerary based on integration of open government data and personal tourist data. The system uses case-based reasoning (CBR) to provide a personalized trip navigation service. The main difference between existing trip information systems and ours is that our system can offers a user-oriented information service. In addition, our system supports Turn-key style contents provision to maximize convenience. Our system can be a good example of the way in which open government data can be used to design a new service.

Consideration in the Interpretation of the Ondam-tang Prescription (온담탕(溫膽湯)의 방론(方論)에 관한 고찰)

  • Choe, Ung-Sik;Jeong, Gi-Hoon
    • Herbal Formula Science
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    • v.22 no.1
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    • pp.65-78
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    • 2014
  • Objectives : The purpose of this study was to investigate the interpretation of the Ondam-tang(Ondam-tang, here-in-after referred to as "ODT") prescription in order to obtain the evidence for clinical applications. Methods : We have analyzed the interpretation on the ODT prescription through translations and comparisons based on classic books about the oriental medical prescriptions. Result : 1. ODT was first mentioned in the Jiyangfang(集驗方) which was quoted in the Waitaimiyao (外臺秘要). After that, in book Sanyinjiyibingzhengfanglun(三因極一病證方論), Chen-yan(陳言) completed and recorded in a book organizing prescriptions of ODT now in frequent use. 2. The Banha(半夏) removes the dam(痰-phlegm) and relieves emesis. The Jinpee(陳皮) encourages strengths, and the Bokryoung composes oneself and produces the water. The Licorice(甘草) relieves people's mind, and the Ginger relieves gastrointestinal problems and relieves emesis. Juk-yeo(竹茹) abate of the fever of the Sangcho(上焦). Jisil(枳實) encourages strength, controlling Samcho(三焦) as releasing the congestion of energy. In these ways, numerous symptoms resulted from the imbalances of the Gallbladder(膽) are treated. 3. Meaning of "on(溫-warm)" in ODT regains the original characteristic of the Gallbladder(膽). 4. Treatment mechanism of ODT is 'cooling the Gallbladder(膽)' and 'remedies Samcho(三焦)' and 'eliminates dam(痰)' and 'cure Kiwool(氣鬱-which is kind of depressions) and Saengyen(生涎-which is kind of phlegm)' and 'removes a mismatch between Gallbladder(膽) and Stomache(胃)'. Conclusion : In this study, we have demonstrated various methodologies. This paper will be useful to the future researchers and clinicians to conduct a study on herbal medicines such as the ODT.