• 구강회복응용과학지
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• 제19권1호
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• pp.1-6
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• 2003

취약한 구강 건강은 손상된 저작의 기능을 유발할 수 있다. 음식의 선택에서 저작의 기능이 중요한 역할을 하는지는 아직 까지도 논쟁의 여지가 있을지라도, 손상된 저작의 기능은 부적절한 음식의 선택을 하게끔하며, 따라서 영양의 섭취를 변화시킨다. 만약 이러한 가설이 맞다면, 저작 기능의 결핍은 일반적 건강에 해로운 것일 것이다. 취약한 구강의 건강과 특정한 위장의 질환 사이의 관계는 비록 과학적으로 확립되지는 않았을지라도 제안되어 왔다. 공공 건강의 정책은 자연치아를 보존함으로써 적절한 영양의 섭취를 가능케 하는 것을 강조하여야 하며, 치과의사들은 의치의 사용과 관련된 영양의 위험을 의식하여야 할 것이다.

• 동의생리병리학회지
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• 제26권3호
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• pp.338-343
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• 2012

Oryeong-san which was first recorded in Shanghanrun describing the treatments of acute febrile disease is one of the frequently used oriental medicines. Oryeong-san has been prescribed for the treatment of symptoms accompanied by edema. The purpose of this study was to examine the diuretic effects of Oryeong-san by different routes of administration. Oryeong-san (100 mg/kg body weight) was administrated by three different routes in Sprague-Dawley rats: intravenous infusion, intraperitoneal injection and oral intake. Oral intake of Oryeong-san significantly increased urinary volume and excretion of $Na^+$, $Cl^-$, and $K^+$ compared to vehicle-treated control group. The effects were concentration-dependent. Intravenously administrated Oryeong-san increased urinary volume and electrolyte excretion but without significance in hydrated (0.02 ml/min/rat for 90 min) anesthetized rats. Similarly, intraperitoneally injected Oryeong-san had no effects on water and urine electrolyte excretion compared with saline control group. These findings suggest that Oryeong-san has different effects on water and electrolyte balance by routes of administration.

• Journal of Nutrition and Health
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• 제32권1호
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• pp.10-16
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• 1999

This study was conducted to figure out the differences of the BMI, blood lipids, blood pressure and nutrient intakes by serum insulin concentration among adults in Korea. Ninety-three subjects(male : n=37, female : n=56) participated in this study. The subjects were grouped by serum insulin concentrations into two groups-hyperinsulinemia group(n=17) and normoinsulinemia group(n=76). Anthropometric measurements, blood lipid profiles, blood pressure, oral glucose tolerance test, and daily nutrient intakes were analyzed. And serum glucose and insulin secretion pattern as shown through and oral glucose tolerance test were performed. BMI (p<0.05) and WHR(p<0.01) were significantly higher in hyperinsulinemic group than in normoinsulinemia group. There was no differences in fasting blood glucose level between groups, but total glucose area (p<0.001) and insulin glucose resistance(p<0.001) were significantly higher in hyperinsulinemia group than in normoinsulinemia higher in hyperinsulinemia group, but HDL-cholesterol(p<0.05), and systolic blood pressure(p<0.05) were significantly higher in hyperinsulinemia group, but HDL-cholesterol(p<0.001) was significantly lower in hyperinsulinemia group. They showed significant differences in energy, carbohydrate, potassium, riboflavin, niacin and dietary fiber intakes(p<0.05), the intake of those nutrients were low in normoinsulinemia group. Further investigation is necessary to determine the effects of amounts and types of carbohydrate and dietary fiber on serum insulin concentrations.

• 한국치위생학회지
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• 제13권1호
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• pp.129-135
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• 2013

Objectives : The purpose of this study was to attempt to lay the foundation for the development of oral health programs geared toward promoting the oral health of low socioeconomic class children. Methods : The subjects of this study have been investigated for the use of children to 96 local children's center. Questionnaire for research purposes are described in more detail under the coordination of child care teachers to students, students to be able to record. The survey was conducted at the Health center. Analyzed the data collected by SPSS 18.0. Results : The findings of the study were as follows: The children were influenced by habits of having a snack in dental caries experience. Higher intake of bread and a lot of children more probability of dental caries experience. I've found a lot of sweet-food intake eleven cakes or fruits and vegetables that children prefer higher dental caries experience was low. Conclusions : Education on dietary behavior for low-income children was necessary because of the high correlation of the relationship between dietary habits and dental caries and diet.

• 대한의생명과학회지
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• 제18권1호
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• pp.10-15
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• 2012

A 12-week repeated-dose oral toxicity study of water-soluble Orostachys japonicus extract (WOJ) was performed in Sprague-Dawley (SD) rats of both genders. Each group of ten rats was orally administered in doses of either 0 or 250 mg/day over a 12-week period. As a result, no WOJ-related changes were observed in terms of survival rate, clinical signs, body weight, or food intake. In addition, no difference in organ weight between the control and treated groups was detected. Furthermore, serum biochemistry parameters revealed some changes within normal ranges although significant decreases in total-bilirubin in the females. In spite of some alterations in serum biochemistry, the clinical signs, body weight changes from food intake, and autoptical remarks indicated that WOJ was not toxic. This study suggests that repeated treatment of O. japonicus very low toxicity and the NOAEL (no observed adverse effect dose) of WOJ exceeds 250 mg/kg in the SD rats.

• Childhood Kidney Diseases
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• 제26권1호
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• pp.63-67
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• 2022

Nephrocalcinosis often occurs in infants and is caused by excessive calcium or vitamin D supplementation, neonatal primary hyperparathyroidism, and genetic disorders. Idiopathic infantile hypercalcemia (IIH), a rare cause of nephrocalcinosis, results from genetic defects in CYP24A1 or SLC34A1. Mutations in CYP24A1, which encodes 25-hydroxyvitamin D 24-hydroxylase, disrupt active vitamin D degradation. IIH clinically manifests as failure to thrive and hypercalcemia within the first year of life and usually remits spontaneously. Herein, we present a case of IIH wih CYP24A1 mutations. An 11-month-old girl visited our hospital with incidental hypercalcemia. She showed failure to thrive, and her oral intake had decreased over time since the age of 6 months. Her initial serum parathyroid hormone level was low, 25-OH vitamin D and 1,25(OH)₂ vitamin D levels were normal, and renal ultrasonography showed bilateral nephrocalcinosis. Whole-exome sequencing revealed compound heterozygous variants in CYP24A1 (NM_000782.4:c.376C>T [p.Pro126Ser] and c.1310C>A [p.Pro437His]). Although her hypercalcemia and poor oral intake spontaneously resolved in approximately 8 months, we suggested that her nephrocalcinosis and renal function be regularly checked in consideration of potential asymptomatic renal damage. Hypercalcemia caused by IIH should be suspected in infants with severe nephrocalcinosis, especially when presenting with failure to thrive.

• 한국치위생학회지
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• 제22권6호
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• pp.521-529
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• 2022

Objectives: The purpose of this study was to determine the factors affecting periodontal disease-related symptoms in adolescents using raw data from the 16th (2020) online survey on adolescent health. Methods: Data were collected from the survey entries, and analyzed using IBM SPSS Statistics 21.0. A multi-sample chi-square test was performed to determine periodontal disease-related symptoms according to demographic characteristics, lifestyles, exercise habits, and psychological factors. Logistic regression analysis was performed to determine factors affecting periodontal disease-related symptoms. Results: Periodontal disease-related symptoms were higher in female, high school-age adolescents, and those with lower economic status. Increased alcohol intake, having breakfast 3 days or less a week, ingesting sweet drinks and fast food three or more times a week, and zero water intake were found to have a greater effect on periodontal disease-related symptoms. Higher levels of stress, fewer hours of sleep, and feeling less healthy were also factors leading to increased periodontal disease-related symptoms. Conclusions: Adolescents have various factors that are associated with periodontal disease. A method to reduce rates of periodontal disease in adolescents should be developed, along with a school oral health education program.

• 치위생과학회지
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• 제11권4호
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• pp.361-365
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• 2011

본 연구는 만 12세 이상 19세 미만의 청소년에서 간식섭취 횟수와 치아우식경험과의 상관성을 확인하고자 2007년 국민건강영양조사 자료에 근거하여 분석한 결과 다음과 같은 결과를 얻었다. 1. 간식섭취 횟수가 1일 2회 이상인 학생이 55.7%로 많았고, 칫솔질 횟수는 1일 2회 미만인 학생이 83.9%로 많았으며, 77.6%의 학생이 치아우식증을 경험한 것으로 나타났다. 2. 간식섭취 횟수와 치아우식경험과의 상관성을 분석한 결과 간식섭취 횟수가 1일 2회 미만 보다 1일 2회 이상인 청소년의 경우 치아우식 경험이 2배정도 높은 것으로 나타났고, 이는 통계적으로 유의한 것으로 조사되었다(OR:2.1, CI:1.1-4.0). 3. 간식 종류별 섭취횟수와 치아우식경험과의 상관성에서는 일 년에 11회 이하 간식을 섭취하는 청소년에 비하여 하루에 3회 이하 섭취하는 청소년들이 치아우식경험이 높은 것으로 나타났으며 통계적으로 유의하지는 않았다(OR:1.5 CI:0.6-3.7). 이상의 결과에 근거하여 청소년의 간식섭취 횟수와 치아우식경험 간의 유의한 상관성이 있음을 확인하였고, 이에 따라 청소년을 대상으로 학교 내에서는 구강건강과 관련된 올바른 간식섭취에 대한 지속적인 영양교육, 식이상담 교육 등이 일상적으로 이루어져야 할 것으로 생각된다. 따라서 전문 치과위생들의 청소년을 위한 이러한 구강관리 교육 및 지침서 등을 개발하고, 보급하는데 적극적인 참여가 필요할 것으로 사료된다. 또한 다양한 간식섭취 종류에 따른 치아우식경험 또는 구강건강과의 상관성에 대한 심층분석이 필요할 것으로 본다.

• 대한후두음성언어의학회지
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• 제13권1호
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• pp.18-22
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• 2002

Background and Objectives : It has been pointed out that alcohol intake in human beings induces changes in voice register and maximum phonation time. These changes supposedly result from injection of the vibratory vocal folds. The purpose of this study was to clarify the voice changes associated with alcohol intake and the changes of laryngeal mucosa. Materials and Methods : The subjects included 29 volunteers, including 20 men and 9 women ranging in age from 22 to 31 years. Alcohol intake was accomplished by oral administration of 23% soju 1 bottle (255cc). Serum alcohol concentration levels were evaluated hourly for 3 h after ingestion of alcohol. Seven measurements were performed at pre-alcohol intake and post-alcohol intake hourly : fundamental frequency, jitter, shimmer, noise to harmonic ratio as the acoustic analysis, maximal phonation time, mean flow rate, and subglottal pressure as the aerodynamic analysis. The changes of laryngeal mucosa were evaluated by flexible laryngoscope at each measurement. Results : By comparing the acoustic and aerodynamic data and laryngeal mucosa before and after alcohol intake, there were not remarkable changes (p>0.05). Conclusion : The voice and laryngeal mucosa have not remarkably changed according to alcohol concentration in this study. Furthermore studies on the voice change induced by multiple alcohol concentrations are required.

• 가정과삶의질연구
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• 제23권2호
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• pp.63-76
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• 2005

Health is the most important factor in the Quality of life. Without appropriate treatment, dental caries could have serious effects on self-esteem, nutrition, and health of a person throughout his/her life. The purpose of this study was to investigate ways to develop a consumer information program that could help improve teens' oral health. To develop an effective information program, we surveyed 1) how teens feel about oral health information in the market, 2) how judiciously they use their information, and 3) how they actually apply the information to practice. On the other hand, we investigated relationships between dietary patterns and dental caries among middle school students. The results indicate a serious lack of oral health information for middle school students. Moreover, we found that the intake of vegetables, fruits and legumes prevents dental caries. Using these results, we developed a system for organizing and conveying the oral health information for teens.