• 한국치위생학회지
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• 제14권6호
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• pp.795-804
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• 2014

Objectives: The purpose of the study was to investigate the relationship between the oral contraceptive pill and periodontal disease in Korean women aged from 19 to 50 years old. Methods: This study selected 1,579 women of childbearing age from 19 to 50 years old from the 5th National Health and Nutrition Survey data analysis(phase 3, 2012) taking the oral examination. The questionnaire consisted of socioeconomic demographic characteristics, health behavior, use of oral contraceptive pills, and periodontal disease. Socioeconomic demographic characteristics included age, marital status, education, monthly income, and vocation. The health behavior included obesity, stress, smoking, subjective oral health status, use of dental floss, tooth brushing, and diabetes mellitus by fasting blood sugar level. Use of oral contraceptive pills was recorded by monthly use and duration. The periodontal disease was documented by yes or no and selected as dependent variable by logistic regression analysis. Results: After revising the taking period of oral contraceptive pill for this study, there was the correlation between the prevalence of periodontal disease and odds ratio(95% CI) 1.288(1.027-1.617). Conclusions: This study will contribute to the direction of policy for an oral contraceptive pill and provide the basic data for counseling for the oral health and the side effects of oral contraceptive pills.

• 대한약리학회지
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• 제17권2호
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• pp.69-74
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• 1981

Increased incidence of myocardial infarction, arteriosclerosis and hypertension in oral contraceptive steroids users has been recognized as serious problem. Evidence have been accumulated that oral contraceptive steroids cause an increase in serum lipid levels, mainly triglyceride as well as an increase in serum cholesterol concentration in some women. Effect of oral contraceptives on serum lipids have been predominantly confirmed in Europian and American women. It should be emphasized that effects of contraceptives may he influenced by differences in nutrition, climate, socioeconomic status and race. The present study was, therefore, attempted to determine the effect of oral contraceptive steroids on serum lipid levels in Korean women and also to demonstrate whether the duration of pill treatment may affect serum lipid levels. Ten women, who had never taken contraceptive steroids, served as a control. One hundred women on combined oral contraceptive steroids were grouped according to the duration of pill use: duration of less than one year(14 women), 1-2 years(12 women), 2-5 years(29 women), 5-10 years(33 women) and more than 10 years(13 women). Serum levels of cholesterol, phosholipid and triglyceride were measured by enzymatic method, Fiske-SubbaRow method and Sugiura method respectively. The results obtained are as follows; 1) Oral contraceptive steroids increased serum cholesterol concentration by 4.8% as compared with cholesterol value of control group. But this increase was not statistically significant. 2) As compared with control value, concentration of serum phospholipid in pill-treated women decreased by 14.3%, which was statistically significant (p<0.05). 3) Concentration of serum triglyceride in pill-treated women increased by 10.6% over control value, but this increase was not statistically significant. 4) Duration of pill-treatment did not affect serum concentrations of cholesterol, phospholipid and triglyceride. From the results mentioned above, it may be concluded that combined oral contraceptive steroids, at least used for subjects involved in this study, decreased serum phospholipid significantly, thereby influencing serum lipid concentration.

• 대한간호학회지
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• 제4권1호
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• pp.121-134
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• 1974

This study is an attempt to evaluate the use of an oral contraceptive by: 1. Deforming the acceptance rate of the oral contraceptive according to socio-demographic characteristics 5. Estimating the duration of the use of the contraceptive f. Discovering reasons why the contraceptive was discontinued 4. Computing the cumulative continuation and discontinuation rate according to socio-demographic characteristics, history of pregnancies, and attitude of husband at the time of selection of the contraceptive. One hundred sixty-eight women of child bearing age (14-49 years), residing in Yonhee Dong, Seoul, Korea and registered as oral contraceptive accepters at Yonsei Community Health Center, were interviewed during a three week period in 1973. The questionnaire was designed to determine the socio-demographic characteristics of the oral contraceptive accepters, the current status of their family planning practice, medical reactions if any, discontinuation practice, and the duration of the use of the contraceptive. The major findings of the study were as follows; 1. The acceptance rate was highest for women between 30 and 34 years of age, the mean age being 34.4 years. 2. Fifty six point five percent of all respondents said that thirty years of age was the ideal age to stop having children. 3. The average number of living children was 3.5 and fifty four point eight percent of respondents felt 2 boys and I girl was the ideal number of children. 4. The average number of pregnancies was 5.2 and the average number of induced abortion was I. 4. 5. Fifty eight point eight percent of the respondents had experience in the use of contraceptive methods in the past. 6. Forty one point seven percent of the respondents replied that they chose the oral contraceptive because, "it was not complicated to use." 7. Sixty four point eight percent of the women said their husband approved of their taking the pill. 8. The cumulative discontinuation rate was sixty point five percent of the total respondents for one year in first segment. 9. Sixty six point nine percent of the respondents had experienced side-effect while using the pill. The side effects for 68.9 percent of these women were castro-intestinal upsets. Twenty point eight percent of the women who had side effects consulted with medical personnel about them. Women who had more education had more side effects. 10. Seventy three point two percent of the women who discontinued the pill did so because of medical reasons. Women who were younger discontinued the pill for personal reasons more-often than older women. Among personal reasons listed for discontinuing the pill was the attitude of the husband. 11. The average duration of continuance of the contraceptive was 5.3 cycles under 29 years of age; 7.4 cycles between 30 and 34 years of age; and 8.4 cycles over 40 years of age. 12. The discontinuation rate was seem to increase sharply in the early cycle and increase more slowly in later cycle. Conclusions and suggestions: Since the attitude of the husband was shown to be important, the current family planning program should be expended to include approach to husband. For women who must use the oral contraceptive, education and support must be enhanced so that the discontinuation rate due to side effects will be decreased.

• Asian Pacific Journal of Cancer Prevention
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• 제15권14호
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• pp.5517-5522
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• 2014

Oral contraceptive use is the most common type of contraception. More than 300 million women worldwide take oral contraceptives every day. However, there is a concern about the relationship with the incidence of cancer. This analytical retrospective study aimed to investigate the relationship between the incidence of cervical and breast cancers and oral contraceptive use in 128 Iranian patients with cervical cancer, 235 with breast cancer and equal numbers of controls. Data were collected through interviews with an organized set of questions. Details were also extracted from patient files. Data were analyzed using Student's t-test, chi-square and Fisher's exact tests, and Pearson's correlation analysis. The result revealed correlations between both cervical and breast cancers and history of contraceptive pills use. While cervical cancer significantly correlated with duration of use of pills, breast cancer had significant correlations with the type of oral contraceptive and age at first use. No significant relationships were found between the two types of cancer and age at discontinuation of oral contraceptives, patterns of use, and intervals from the last use. The use of oral contraceptives may triple the incidence of cervical cancer and doubles the incidence of breast cancer. Therefore, performing Pap smears every six months and breast cancer screening are warranted for long-term oral contraceptive users.

• Clinical and Experimental Reproductive Medicine
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• 제13권2호
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• pp.95-100
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• 1986

During the past decade great advance has been made in contraceptive technology. The development and subsequent modification of oral steroid contraceptive together with the improved design of other contraceptives have tremendously altered the contraceptive practise of complete throughout the world. At the present time one of most complex issue is the population explosion. In Korea the population growth rate is remarkably decreased from 3% in 1960s to 1.7% in 1984. Increasing proportion of women practising family planning and improved contraceptive methods have contributed on remarkable reduction of fertility rate. But still about half of married women not involved in family planning practise. One of the reasons why that so many women haven't participated in family planning should be undesirable side effects or inconvenience of currently available contraceptives. So we need more research to develop newer, safer and more effective contraceptive to solve the problems. According to recent report on the family planning program achievement in Korea, sterilization (male and female) is most popular, leading contraceptive method (330 cases/1000 fertile persons) and the I.U.D. (167.5/1000), condom (132.9/1000) and oral pill (61.1/1000) were followed by in the order of favorite choice of contraceptive (KIPH, Family planning evaluation report, 1984; KIPH Family plan Service Statistics, 1981-1984). In present paper the present status and knowledge of contraceptives will be summarized.

• 보건의료산업학회지
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• 제8권4호
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• pp.221-229
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• 2014

Breast cancer is increasing at a remarkable rate in Korea. We investigated the association between oral contraceptive use and breast cancer in Korean women. Using the 5th Korea National Health and Nutrition Examination Survey data, 8,495 women aged over 30 years are analyzed. Furthermore, the data used in this study is obtained using a complex sampling method in order that it is generalized. The previous studies in Korea, were not statistically significant due to the relatively short duration during which oral contraceptives had been available. However, the longer duration of oral contraceptive use exhibits tendency to increase the risk of breast cancer. Women using oral contraceptives, particularly for more than two years have an increased occurrence of breast cancer compared with women who do not use oral contraceptives. This result reflects the late introduction of oral contraceptives in Korea compared with developed countries. The recent increase in interest about the use of oral contraceptives has been increasing for a variety of reasons. Therefore, it is necessary for continuous and specific clinical studies to examine the connections between the first use of oral contraceptives, oral contraceptives use duration, adverse effects of oral contraceptives and breast cancer in order to develop strategies for preventing breast cancer.

• 한국임상약학회지
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• 제29권1호
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• pp.33-44
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• 2019

Objective: This study attempts to gauge the necessity of contraceptive education for women defecting from North Korea (NKDWs). Methods: We conducted in-depth interviews with six NKDWs who had lived in the Republic of Korea (ROK) for more than three years, to understand the subjects' perceptions, experiences, and opinions regarding contraception. Thematic analyses were performed using qualitative data provided in the survey results. Results: Before their defections from North Korea, none of the NKDWs had received any sex education. Loop is the only contraceptive method available to married women in ROK. After defection, NKDWs were provided information about contraceptive options available in China, but they could not fully understand this information. Furthermore, the information they received was not accurate. Thus, NKDWs had a high need for contraceptive sex education. As per our survey, their preferred education method was at least 3 lessons plus 1 : 1 counseling, as necessary. Conclusion: This study indicates that a necessity exists for development of a sex education program for NKDWs to enhance their contraceptive knowledge. Thus, government and health managers have a role to play in developing such a program.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제41권2호
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• pp.59-65
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• 2015

The extraction of third molars is a common task carried out at dental/surgery clinics. Postoperative pain is one of the two most common complications of this surgery, along with dry socket. Knowledge of the frequent risk factors of this complication is useful in determining high-risk patients, planning treatment, and preparing the patients mentally. Since the risk factors for postoperative pain have never been summarized before while the risk factors for dry socket have been highly debated, this report summarizes the literature regarding the common predictors of postextraction pain. Except for surgical difficulty and the surgeon's experience, the influences of other risk factors (age, gender and oral contraceptive use) were rather inconclusive. The case of a female gender or oral contraceptive effect might mainly be associated with estrogen levels (when it comes to dry socket), which can differ considerably from case to case. Improvement in and unification of statistical and diagnostic methods seem necessary. In addition, each risk factor was actually a combination of various independent variables, which should instead be targeted in more comprehensive studies.

• Archives of Pharmacal Research
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• 제13권4호
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• pp.379-381
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• 1990

The effect of calcium gluconate on estrogen (estradiol) serum level as well as follicle stimulating hormone level was studied. Our results revealed that oral administration of calcium gluconate (100 mg/kg body wight) to adult non-pregnant female rabbits caused a significant increase of serum levels of estradiol and follicle stimulating hormone. On the other hand, oral contraceptive (Norminest tablets) decreased significantly follicle stimulating hormone serum level, while combined administration of calcium gluconate and oral contraceptive caused significant increase of serum level of follicle stimulating hormone compared with control values. Also, concurrent administration of calcium gluconate and Norminest tablet increased significantly the rate of conception compared with group recieved Norminest tablets only. These results indicated that combined administration of calcium and oral contraceptives must be cautiously.

• 디지털융복합연구
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• 제11권12호
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• pp.569-576
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• 2013

본 연구는 우리나라 여성을 대상으로 경구피임약 복용과 치주질환의 관련성을 분석하여 피임약이 치주질환에 미치는 영향을 파악하고자 하였다. 연구자료는 제4기 국민건강영양조사 자료 중 2008년과 2009년 결과를 이용하였고, 19-50세 폐경 전 가임여성 1,101명을 대상자로 선정하였다. 인구사회경제적 요인과 구강보건행태, 피임약 복용기간 및 치주질환 상태를 파악하여 chi-square 검정과 logistic regression 분석을 통해 경구피임약 복용과 치주질환과의 관련성을 조사하였다. 그 결과, 인구사회경제적 요인 중 연령과 결혼여부, 흡연상태가 경구피임약 복용과 통계적인 유의성을 나타내었다. 현재 경구피임약 복용여부와 치은조직 상태는 연관성이 없는 것으로 확인되었다. 치주질환 유병율은 연령에 따라 증가하였지만, 피임약 복용기간과 흡연, 칫솔질과 치간관리를 포함한 구강보건형태와는 통계적으로 유의한 차이를 보이지 않았다. 마지막으로 logistic regression 분석 결과, 혼란변수 보정여부에 따라 큰 차이 없이 치주질환은 경구피임약 복용여부 및 복용기간과 관련성이 없는 것으로 확인되었다.