• The Journal of the Korean dental association
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• v.58 no.1
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• pp.28-37
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• 2019

This study aimed to introduce what Korea national oral health surveys are and examine recent oral health status in Korean children. Korea Government has implemented national oral health-related surveys during the past two decades. The surveys with oral health examination are Korean Children's National Oral Health Survey (KCNOHS) since 2000 in 5-year-old and 12-year-old children and Korea National Hhealth and Nutrition Examination Survey (KNHANES) since 2007 aged 1 year and more. KCNOHS provides the information about the distribution of prevalence of dental caries, gingival health, behavioral factors, and dental clinic demands etc. KNHANES has huge amount of health data for representative Korean population including oral health and general conditions. Based on KCNOHS, the prevalence of dental caries and its experience has decreased steadily, and the status of oral hygiene and preventive treatment called sealents has been also improved after the year of 2000. However, there is still a gap to reach to those of Western developed countries. Therefore, more effective oral health policy plans and strategies for Korean children and adolescents are needed to prevent and manage for dental caries in private and clinical field of dentistry with public sector.

• Journal of Technologic Dentistry
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• v.45 no.1
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• pp.14-20
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• 2023

Purpose: This study was conducted to provide basic data for a health promotion program by analyzing the effects of high school students' mental health-related factors on oral symptom experiences. Methods: This study included 24,833 high school students who participated in the screening and health survey in the "17th (2021) Adolescent Health Behavior Survey." SPSS software (SPSS Statistics ver. 21.0; IBM) was used for statistical analysis. Multiple sample logistic regression analysis was performed. The significance level was set to 0.05. Results: The result of the analysis on the effect of mental health revealed that oral symptom experience was low in students without depression and suicidal thoughts. Oral symptom experience was high in students with stress perception. Additionally, the experience of oral symptoms was low when there was sufficient subjective sleep. Conclusion: Therefore, it is necessary to develop a customized oral health education program for early detection of oral symptoms and oral health promotion in high school students. Furthermore, it suggests the need for strategies and continuous oral health guidance to practice proper oral health habits to maintain healthy oral conditions.

• The Journal of Korea Assosiation for Disability and Oral Health
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• v.5 no.2
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• pp.96-99
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• 2009

Macroglossia is a tongue pathology of multiple etiology as systemic disease like cerebral palsy and Down syndrome etc. It can cause abnormal oral conditions including anterior open bite or dyspnea by changing occlusion and oral habits. So many handicapped children who have macroglossia need to get surgery of large tongue to improve esthetics, function, and treatment stability. The purpose of this report is to evaluate 2 patients, one has cerebral palsy and the other lymphangioma, who have experience of glossectomy with review of literature.

• Imaging Science in Dentistry
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• v.51 no.4
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• pp.461-466
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• 2021

Fibro-osseous lesions are a poorly defined category of conditions affecting the jaws and craniofacial bones, and include developmental lesions, reactive or dysplastic lesions, and neoplasms. Fibrous dysplasia and ossifying fibroma are the 2 main types of fibro-osseous lesions affecting the jaw, and ossifying fibroma is a true benign neoplasm of the bone-forming tissues with several well-recognized variants ranging from innocuous to extensively aggressive lesions. However, multiple simultaneous fibro-osseous lesions of the jaw bones involving all quadrants are exceedingly rare. One such case diagnosed by conventional radiography and computed tomography is discussed here.

• Journal of dental hygiene science
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• v.7 no.4
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• pp.213-218
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• 2007

The purpose of this study was to analyze the effects of dentistry users' perception of concern about oral health on their perception of oral health and behaviors. For this purpose, the researcher sampled the outpatients who had used 2 dentistries in Kangnam, Seoul and another 2 dentistries in Kangbuk, Seoul and a hospital attached to a dental college in Bundang, Kyonggi-do and thereby, conducted a self-administered questionnaire survey from April 4 through 28, 2006. 291 responses from the survey were analyzed using the SPSS 12.0 statistical program. The results of this study can be summarized as follows; 1. 45.0% of the patients perceived that their oral conditions were not healthy, 32% thought normal for their oral conditions and 23% felt healthy for their oral conditions. 2. Less women (44.1%) felt healthy for their oral conditions than men (46.3%). 3. The more negative patients' perception of their oral health was, they were more likely (55.1%) to rely on relatives for choice of a dentistry. 45.0% of this group worried about their oral health always, 15.1% were more or less worried, and 11.9% of them felt that their oral health was good(P < 0.05). 4. 66.0% of the subjects worried about their oral health sometimes, and 27.8% of them worried always, and 6.2% worried little. There was no significant gender difference, but the older they were, they worried more always(P < 0.05). 5. 93.8% of the group who worried about their oral health always had ever had their teeth scaled, and 65.8% of them had regularly had their teeth scaled. Such ratios differed significantly from the group who worried about their oral health sometimes (49.7% and 46.2%, respectively). The three groups differed in terms of regular checks significantly: 56.6%, 45.3% and 33.3%, respectively. And the rate of visiting the dentistry without fail was significantly highest (71.6%) in the first group (P < 0.05).

• Journal of dental hygiene science
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• v.17 no.5
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• pp.433-438
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• 2017

Relative to its incidence, oral cancer has serious negative social effects. The exact causes of oral cancer have not been clarified, but many studies have implicated smoking and drinking. However, the fundamental mechanism of oral cancer causation has yet to be elucidated. Lysophosphatidic acid (LPA) augments epithelial mesenchymal transition (EMT) and development of various cancer cells. However, a detailed mechanistic explanation for LPA-induced EMT and the effects of EMT-promoting conditions on oral squamous cell carcinoma development remain elusive. In the present study, a quantitative reverse transcription polymerase chain reaction was used to analyze TWIST1, Slug, E-cadherin, and glyceraldehyde-3-phosphate dehydrogenase (GAPDH) transcript expression. Immunoblotting was used to analyze TWIST1, Slug, E-cadherin, and GAPDH protein expression. siRNAs were used to silence TWIST1 and Slug transcript expression. A matrigel-coated in vitro invasion insert was used to analyze oral cancer cell invasion. The results of the present study show that the expression levels of TWIST1 and Slug, which are EMT factors, were increased by LPA treatment in YD-10B oral squamous cell carcinoma. Conversely, E-cadherin expression was significantly reduced. In addition, transfection of the cells with TWIST1 and Slug siRNA strongly inhibited LPA-induced oral cancer cell invasion. The present study shows that TWIST1 and Slug mediate LPA-induced oral cancer cell EMT and invasiveness. The present study confirmed the mechanism by which LPA promotes oral cancer cell development, with TWIST1 and Slug providing novel biomarkers and promising therapeutic targets for oral cancer cell development.

• Journal of Korean Dental Science
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• v.15 no.2
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• pp.101-111
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• 2022

The purpose of laboratory tests in the field of oral medicine can be divided into two categories: (1) medical evaluation of patients with systemic diseases that are planning to receive dental care and (2) diagnosis of patients with certain oral diseases. First, laboratory tests are commonly used to evaluate patients with systemic diseases who need dental management. A combination of multiple tests is usually prescribed as a test panel to diagnose and assess a specific disease. Test panels closely related to oral medicine include those for rheumatoid arthritis, connective tissue disease/lupus, liver function, thyroid screening, anemia, and bleeding disorders. Second, laboratory tests are used as auxiliary diagnostic methods for certain oral diseases. They often provide crucial diagnostic information for infectious diseases caused by bacteria, fungi, and viruses that are associated with pathology in the oral and maxillofacial regions. Laboratory tests for infectious diseases are composed of growth-dependent methods, immunologic assays, and molecular biology. As the field develops, further application of laboratory tests, including synovial fluid analysis in temporomandibular joint disorders, salivary diagnostics, and hematologic biomarkers associated with temporomandibular disorders and orofacial pain conditions, is currently under scrutiny for their reliability as diagnostic tools.

• Journal of Korean society of Dental Hygiene
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• v.13 no.2
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• pp.305-313
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• 2013

Objectives : This study has attempted to investigate subjective oral health awareness, oral health behavior and analyze how the results are correlated with oral health-related quality of life against middle school students. Methods : A self-administered questionnaire survey was performed against 552 students from three middle schools in Changwon. A frequent analysis was conducted on research subjects' general characteristics, oral health awareness, oral health behavior. In addition, t-test and ANOVA were carried out to analyze oral health-related quality of life by the general characteristics, oral health awareness and oral health behavior. Results : In terms of oral health-related quality of life by general characteristics, the quality of life on oral symptoms was higher at lower school grades (p<0.05). In terms of social welfare, oral health-related quality of life was higher as parents' monthly income increased (p<0.05). Oral health-related quality of life was high in oral symptoms when there was no interest in oral health, in functional limitation, emotional welfare and social welfare when there is some oral health-related knowledge (p<0.05) and in all sub categories when oral conditions are healthy (p<0.05). Conclusions : The results of this study has come up with important information for improvement of oral health-related quality of life in middle school students by investigating the correlations between oral health awareness and oral health-related quality of life.

• International Journal of Oral Biology
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• v.36 no.2
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• pp.71-78
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• 2011

Using whole cell current- and voltage-clamp recording we investigated the characteristics and pharmacology of group I metabotropic glutamate receptor (mGluR)-mediated responses in rat medial vestibular nucleus (MVN) neurons. In current clamp conditions, activation of mGluR I by application of the group I mGluR agonist (R,S)-3,5-dihydroxyphenylglycine (DHPG) induced a direct excitation of MVN neurons that is characterized by depolarization and increased spontaneous firing frequency. To identify which of mGluR subtypes are responsible for the various actions of DHPG in MVN, we used two subtype-selective antagonists. (S)-(+)- alpha-amino-a-methylbenzeneacetic acid (LY367385) is a potent competitive antagonist that is selective for mGluR1, whereas 2-methyl-6-(phenylethynyl)-pyridine (MPEP) is a potent noncompetitive antagonist that is selective for mGluR5. In voltage clamp conditions, DHPG application increased the frequency of spontaneous and miniature inhibitory postsynaptic currents (IPSCs) but had no effect on amplitude distributions. Antagonism of the DHPG-induced increase of miniature IPSCs required the blockade of both mGluR1 and mGluR5. DHPG application induced an inward current, which can be enhanced under depolarized conditions. DHPG-induced current was blocked by LY367385, but not by MPEP. Both LY367385 and MPEP antagonized the DHPG-induced suppression of the calcium activated potassium current ($I_{AHP}$). These data suggest that mGluR1 and mGluR5 have similar roles in the regulation of the excitability of MVN neurons, and show a little distinct. Furthermore, mGluR I, via pre- and postsynaptic actions, have the potential to modulate the functions of the MVN.

• Imaging Science in Dentistry
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• v.51 no.2
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• pp.137-148
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• 2021

Purpose: This study aimed to assess the computer monitors used for analysis and interpretation of digital radiographs within the clinics of the Oral Health Centre of Western Australia. Materials and Methods: In total, 135 computer monitors(3 brands, 6 models) were assessed by analysing the same radiographic image of a combined 13-step aluminium step wedge and the Artinis CDDent 1.0^® (Artinis Medical Systems B.V.^®, Elst, the Netherlands) test object. The number of steps and cylindrical objects observed on each monitor was recorded along with the monitor's make, model, position relative to the researcher's eye level, and proximity to the nearest window. The number of window panels blocked by blinds, the outside weather conditions, and the number of ceiling lights over the surgical suite/cubicle were also recorded. MedCalc^® version 19.2.1 (MedCalc Software Ltd^®, Ostend, Belgium, https://www.medcalc.org; 2020) was used for statistical analyses(Kruskal-Wallis test and stepwise regression analysis). The level of significance was set at P<0.05. Results: Stepwise regression analysis showed that only the monitor brand and proximity of the monitor to a window had a significant impact on the monitor's performance (P<0.05). The Kruskal-Wallis test showed significant differences (P<0.05) in monitor performance for all variables investigated, except for the weather and the clinic in which the monitors were placed. Conclusion: The vast performance variation present between computer monitors implies the need for a review of monitor selection, calibration, and viewing conditions.