• Journal of Oral Medicine and Pain
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• v.22 no.2
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• pp.327-339
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• 1997

This study aimed at evaluating tile relationship between pressure pain threshold(PPT) and electromyographic(EMG) activity in 30 healthy volunteers and 30 patients with temporomandibular disorders. PPTs were determined with electric pressure algometry over masseter, temporalis anterior, sternocleidomastoid, and trapezius muscle during resting and clenching. To obtain more reliable result, two examiners measured PPTs two times on each muscles, randomly. Resting and clenching EMG activity and tenderness of all muscles were measured to evaluate the relationship with PPTs. The collected data were processed by SAS/STAT program. The obtained results were as follows : 1. Pressure pain thresholds in tendered muscles were lower than those in non-tendered muscles. This tendency was more prominant in masticatory muscles than in cervical muscles and in clenching than in resting. 2. There ware a tendency of higher PPTs in unaffected side than in affected side, but there were no significant difference statistically. 3. There wert no difference of PPTs between in preferred side and in ipsilateral side, significantly. 4. There was a significantly positive correlation between resting and clenching PPTs, but there were no correlation between PPTs and EMG activities. 5. Comparison of EMG activity between in higher group and in lower group by resting PPTs didn't show any significant difference. But resting EMG activity in the higher group of clenching PPTs were lower, on the contrary, clenching activity were higher than those in lower groups of clenching PPTs. From this results, the author concluded that the clenching PPTs was more important than resting PPTs in diagnosis of muscle dysfunction. And the author recommanded that all of three following test were performed for the proper diagnosis and treatment of orofacial Pain : muscle tenderness, EMG activity, and PPT.

• The Journal of the Korea institute of electronic communication sciences
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• v.8 no.2
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• pp.371-378
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• 2013

This study was attempted in order to offer basic data for enhancing oral health by surveying the activity limitation realities caused by oral disease in university students and then by analyzing its relevant factors. As a result of research, university students' activity limitation experience rate accounted for 24.1%. The average number of activity limitation days stood at 0.44 day. Matters related to university students' activity limitation included housing type as for socio-demographic characteristics, and busyness in daily life, difficulty for supplying school expenses, temporal burden given using dental treatment, and difficulty for transportation given using dental treatment as for individual characteristics. In case of feeling difficulty for raising school expenses, the possibility was indicated to be high in activity limitation experience, illness experience, experience of having trouble in performing schoolwork, and schoolwork loss experience. Also, in case of feeling difficulty for transportation given using dental treatment, the possibility was indicated to be high in experiencing a trouble in performing schoolwork and a loss of schoolwork. Accordingly, a national interest and support are earnestly demanded in order to establish the more systematized oral health level and to increase oral health promotion.

• Food Science and Biotechnology
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• v.18 no.2
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• pp.556-560
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• 2009

Xanthorrhizol, a sesquiterpene isolated from Curcuma xanthorrhiza Roxb., was used to investigate its effect on reducing the saliva and multi-species oral biofilms consisting of Streptococcus mutans, Streptococcus sanguis, and Actinomyces viscosus by anti-biofilm and confocal laser scanning microscopy (CLSM) assays. Xanthorrhizol exhibited significant antibiofilm activity in the dose- and time-dependent manners. Exposure to 2 and $5{\mu}g/mL$ xanthorrhizol for 30 min remained <50% of saliva and multi-species biofilms formed for 24 hr. In addition, exposure to $10{\mu}g/mL$ xanthorrhizol for 30 min reduced 65 and 77% of 24 hr saliva and multi-species oral biofilms, respectively. CLSM results visually demonstrated that xanthorrhizol reduced bacterial viability in the saliva and multi-species oral biofilms. These results suggest that C. xanthorrhiza Roxb. containing xanthorrhizol with strong anti-biofilm activity can be employed as a plant source for oral care functional foods.

• Journal of Korean Dental Hygiene Science
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• v.4 no.1
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• pp.79-87
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• 2021

Background: The purpose of the present study was to confirm the degree of physical activity and oral health behaviors of adolescents, and to investigate the relationship between them. Methods: The present study utilized data from the 15th (2019) Korea Youth Risk Behavior Web-Based Survey data, which included a total of 57,303 adolescents for analysis. Statistical analysis was performed using PASW Statistics 21.0. The significance level for significance was set at 0.05. Results: The rate of toothbrushing before sleeping was 1.152 times higher in the group that performed muscle strengthening exercises more than 3 times a week than in the group that did not (p < 0.001). The rate of use of oral hygiene products was 1.246 times higher in the group that performed physical activity for 60 min or more every day than in the group that did not, and 1.207 times higher in the group that performed muscle strength exercise at least 3 times a week than in the group that did not (p < 0.001). Conclusions: Adolescents who engaged in physical activities had a high rate of practice for some oral health behaviors. These results suggested that the group with positive health behaviors has a higher rate of oral health behavior practice, showing that health behaviors are highly interrelated.

• Journal of Oral Medicine and Pain
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• v.38 no.2
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• pp.187-201
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• 2013

The purpose of this study is to investigate the relationship between the symptoms and adolescents TMD patient's personal characteristics, physical activity, and cyber leisure activity. We investigated 219 adolescents patients aged 11 to 19 who visited the Department of Oral Medicine in Pusan National University Dental Hospital and 90 control group, personal characteristics, physical activity, cyber leisure activities, and the relationship of the TMD symptoms, and the following results were obtained. TMD group compared to the control group, the sleep quality was lower, cyber-leisure time is longer and more frequent. In TMD group, the shorter sleep time was, first visit NAS was higher. The more stress was, physical activity was less. The more TMD symptoms were severe, cyber-leisure time was shorter.

• Journal of Oral Medicine and Pain
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• v.43 no.1
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• pp.1-7
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• 2018

Purpose: The purpose of the study was to investigate the influences of hyaluronic acid on the candidacidal activities of lysozyme, the peroxidase system, and the glucose oxidase-mediated peroxidase (GO-PO) system at different concentrations of antimicrobial enzymes. Methods: Hyaluronic acid was used at a final concentration of 0.5 mg/mL. Hen egg-white lysozyme (HEWL) was used at concentrations ranging from 10 to $100{\mu}g/mL$. The peroxidase system included bovine lactoperoxidase (bLPO), potassium thiocyanate (KSCN, 1 mM), and hydrogen peroxide ($100{\mu}M$). The GO-PO system included bLPO, KSCN (1 mM), glucose oxidase (10 units/mL), and glucose ($30{\mu}g/mL$). The final concentration of bLPO in the peroxidase and GO-PO systems ranged from 12.5 to $100{\mu}g/mL$. Candida albicans strains ATCC 10231, 11006, and 18804 were utilized. Candidacidal activities of antimicrobials and the influence of hyaluronic acid on their candidacidal activities were determined based on colony forming units. Results: Candidacidal activities of the peroxidase and GO-PO systems increased with increasing concentrations of bLPO. This tendency was the same in the presence or absence of hyaluronic acid. Candidacidal activity of HEWL was not significantly concentration-dependent. Candidacidal activities of the GO-PO system were higher than those of the corresponding peroxidase system. Candidacidal activity was inhibited in the presence of hyaluronic acid in the following order: HEWL, the peroxidase system, and the GO-PO system. Conclusions: Hyaluronic acid inhibited the candidacidal activities of HEWL, the peroxidase system, and the GO-PO system. The GO-PO system exhibited better candidacidal activity than HEWL and the peroxidase system both in the presence and absence of hyaluronic acid.

• International Journal of Oral Biology
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• v.35 no.4
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• pp.169-175
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• 2010

Cholinesterase (ChE) is one of the most ubiquitous enzymes and in addition to its well characterized catalytic function, the morphogenetic involvement of ChE has also been demonstrated in neuronal tissues and in non-neuronal tissues such as bone and cartilage. We have previously reported that during mouse tooth development, acetylcholinesterase (AChE) activity is dynamically localized in the dental epithelium and its derivatives whereas butyrylcholinesterase (BuChE) activity is localized in the dental follicles. To test the functional conservation of ChE in tooth morphogenesis among different species, we performed cholinesterase histochemistry following the use of specific inhibitors of developing molar and incisors in the hamster from embryonic day 11 (E11) to postnatal day 1 (P1). In the developing molar in hamster, the localization of ChE activity was found to be very similar to that of the mouse. At the bud stage, no ChE activity was found in the tooth buds, but was first detectable in the dental epithelium and dental follicles at the cap and bell stages. AChE activity was found to be principally localized in the dental epithelium whereas BuChE activity was observed in the dental follicle. In contrast to the ChE activity in the molars, BuChE activity was specifically observed in the secretory ameloblasts of the incisors, whilst no AChE activity was found in the dental epithelium of incisors. The subtype and localization of ChE activity in the dental epithelium of the incisor thus differed from those of the molar in hamster. In addition, these patterns also differed from the ChE activity in the mouse incisor. These results strongly suggest that ChE may play roles in the differentiation of the dental epithelium and dental follicle in hamster, and that morphogenetic subtypes of ChE may be variable among species and tooth types.

• International Journal of Oral Biology
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• v.44 no.4
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• pp.165-172
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• 2019

Berberine has been used clinically for more than a decade to treat various diseases, has been shown to be effective in osteoblast differentiation, and is a potential treatment option for osteoporosis. However, compared with existing osteoporosis drugs, berberine is somewhat less effective. This study aimed to identify a new compound with efficacy superior to that of berberine. The osteogenic activities of various berberine derivatives were evaluated via cell differentiation in C2C12 preosteoblast cell lines. Alkaline phosphatase (ALP) staining assay and structure-activity relationship demonstrated that compound 2b had a potent osteogenic effect. Furthermore, compound 2b dose dependently increased ALP activity and showed no toxicity at the effective concentration, indicating its efficacy. Additionally, compound 2b upregulated BMP2-induced transcriptional activity in a promoter activity assay using ALP, BSP, and OC promoters.

• The Journal of the Korean dental association
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• v.9 no.1
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• pp.59-62
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• 1971

An electromyographic analysis of the buccinator muscle was undertaken, by use of surface electrode. Electromyograms were made from 30 subjects with normal dentition during various oral activity, The results were as follows; 1. No buccinator activity was elicited during slowly opening and closing the mouth. 2. The majority of subjects showed buccinator activity while biting hard, protracting the mandible, and retracting the mandible. 3. The buccinator muscle was found to be markedly and consistently active during swallowing, blowing, sucking and masticating. 4. The buccinator activity during pulling the lips against the teeth was of equal potential with pulling the lips laterally. 5. The buccinator muscle on the working side was more active than the buccinator muscle on the balancing side.

• YAKHAK HOEJI
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• v.49 no.5
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• pp.365-369
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• 2005

The inhibitory effect of ferulic acid and related phenolic compounds on the growth of normal cell lines and can­cer cell line was evaluated by the MTT and XTT methods. Ferulic acid decreased the cell viability of human skin melanoma cells by the MTT method and the cell adhesion activity of human oral epithelioid carcinoma cells by the XTT method. These results suggest that ferulic acid has a potential anticancer activity.