• 한국치위생학회지
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• 제11권2호
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• pp.263-275
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• 2011

Objectives : This study was performed analysis of Halitosis components following by subjective cognition of halitosis and Oral State in order to provide basic data for halitosis prevention and establish a device to efficiently eliminate halitosis and analyze the factors that affect the halitosis. Methods : 80 adults were participated who visited at the Dental Clinic in Kyoung-gi do, on the period of the March to September in 2010. The obtained results, through the oral examination, halitosis check and interview, Individually, were as followings. Results : According to the ammonia level was a high relationship between sex, CPI, Tongue plaque, DMFT index which were statistically significant (p<0.05). Total oral gas level was a relationship between VAS, tongue plaque, DMFT index(p<0.05). The Correlation coefficient between the Hydrogen sulfide level and Methyl mercaptan was estimated as r=0.534(p<0.01). As for the multiple regression analysis result, there have been selected dimethyl sulfide and Tongue plaque, Gingival index as factors affecting Bridge, Methyl mercaptan level is as factors affecting Hydrogen sulfide level. Conclusions : There was relationship between the periodontal disease and Ammonia gas component, hydrogen sulfide, dimethyl sulfide, methyl mercaptan. Which were statistically significant total oral gas level and oral variables. Such dental caries as the prevention or early treatment of periodontal disease.

• 한국치위생학회지
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• 제15권2호
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• pp.217-223
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• 2015

Objectives: The purpose of this study is to investigate cognitive function, performance of activities of daily living, and recognition on oral health with the cognitive function testto dementia or dementia-suspected patients in the outpatients. Methods: The subjects were 94 dementia or dementia-suspected patients visiting C University hospital for the dementia test. Study instruments included Korea Mini-Mental State Examination KMMS, The Bayer-Activities of Daily Living Scale; B-ADL, Seoul-Instrumental Activities of Daily Living; S-IADL, Global Deterioration Scale; GDS, Korean Dementia Screening Questionnaire; KDSQ, and underlying diseases. Results: Dementia or dementia-suspected patients were 42 by KMMSE test, 25 patients had impaired functioning of daily living by B-ADL test, 27 patients showed the presence of depression by GDS test, and 45 patients showed impaired functioning of daily living. There was a statistically significant difference in the subjective recognition on oral health conditions. There was a statistically significant difference in the subjective recognition on oral health conditions by ADL. There was a positive correlation between the cognitive function and ADL performance. Higher cognitive function is proportional to ADL performance. Conclusions: The cognitive function was closely associated with ADL and subjective oral health conditions.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제43권2호
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• pp.77-82
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• 2017

Objectives: The aim of this study was to compare the mechanical resistance of four different osteosyntheses modeled in two different sagittal split ramus osteotomy (SSRO) designs and to determine the linear loading in a universal testing machine. Materials and Methods: An in vitro experiment was conducted with 40 polyurethane hemimandibles. The samples were divided into two groups based on osteotomy design; Group I, right angles between osteotomies and Group II, no right angles between osteotomies. In each group, the hemimandibles were distributed into four subgroups according to the osteosynthesis method, using one 4-hole 2.0 mm conventional or locking plate, with or without one bicortical screw with a length of 12.0 mm (hybrid technique). Each subgroup contained five samples and was subjected to a linear loading test in a universal testing machine. Results: The peak load and peak displacement were compared for statistical significance using PASW Statistics 18.0 (IBM Co., USA). In general, there was no difference between the peak load and peak displacement related to osteotomy design. However, when the subgroups were compared, the osteotomy without right angles offered higher mechanical resistance when one conventional or locking 2.0 mm plate was used. One locking plate with one bicortical screw showed higher mechanical resistance ($162.72{\pm}42.55N$), and these results were statistically significantly compared to one conventional plate with monocortical screws (P=0.016) and one locking plate with monocortical screws (P=0.012). The difference in peak displacement was not statistically significant based on osteotomy design or internal fixation system configuration. Conclusion: The placement of one bicortical screw in the distal region promoted better stabilization of SSRO. The osteotomy design did not influence the mechanical behavior of SSRO when the hybrid technique was applied.

• 한국치위생학회지
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• 제8권4호
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• pp.219-228
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• 2008

The purpose of this study was to examine the oral health status and oral health care of adults using dental clinics and the relationship between their oral health state and oral health care. The subjects in this study were 219 patients who visited dental clinics in Gyeonggi province between February and April 2008. A dental checkup and survey were implemented, and SPSS 12.0 program was utilized to analyze the collected data. The findings of the study were as follows: 1. The DT, MT and FT rates of the respondents who used oral hygiene supplies respectively stood at 30.7, 24.6 and 24.6 percent, which were all low. The gaps between them and the others were statistically significant. The DMFT index of the users of oral hygiene supplies was 12.3, which was high, but the difference between them and the others was not statistically significant. 2. The DT rate of those who got a dental checkup on a regular basis stood at 20.8 percent, which was low. The gap between them and the others was statistically significant. Both the MT and FT rates of the former numbered 28.8 percent, which was low, but the gap between them and the others was statistically insignificant. The DMFT index of the respondents who got a regular dental checkup was 12.8, which was high, and the gap between them and the others was statistically significant. 3. The DT and FT rates of respondents who had ever had their teeth scaled respectively stood at 24.6 and 27.1 percent, which were both low, and the differences between them and the others were statistically significant. The MT rate of the former was 27.1 percent, which was low, but the gap between them and the others was statistically insignificant. The DMFT index of those who had ever had their teeth scaled was 12.2, which was high, and the gap between them and the others was statistically significant. The above mentioned findings suggested that there was a very close relationship between oral health care and oral health status. Therefore people in general should be encouraged to pay more attention to their own oral health care, and they should be well informed about how to take care of the oral cavity to promote their oral health.

• 한국산학기술학회논문지
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• 제12권12호
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• pp.5648-5654
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• 2011

본 연구는 치과보철물장착자의 구강위생관리 교육경험 실태를 파악하고자 2011년 3월부터 6월까지 서울과 경기도에 거주하고 있는 18세 이상에서 65세 미만의 성인 267명을 대상으로 설문조사를 실시하였으며, SPSS 11.5 program을 이용하여 분석한 결과 다음과 같은 결론을 얻었다. 구강위생관리용품사용에 관한 교육 실태에서 미혼자는 기혼자 보다 구강위생용품사용은 치아건강에 좋다고 인식하였고, 18-39세가 40-64세 보다 구강위생용품사용은 치아 건강에 좋고, 반드시 사용해야한다고 인식하였다. 구강위생용품사용을 사용하고 있는 경우는 사용하지 않는 경우 보다 구강위생용품사용은 치아건강에 좋다, 반드시 사용해야 한다고 인식하였고, 보철물 닦는 방법과 구강위생용품 선정방법에서 교육만족도가 높았다. 이상의 결과에서 치과보철물장착자의 구강위생관리용품에 대한 인식은 높았으나 교육만족도는 이보다 낮게 나타난 결과로 치과의료기관에서는 치과보철물장착자를 대상으로 한 보다 실질적인 환자 교육시스템이 운영되어야 할 것으로 생각된다.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제34권6호
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• pp.644-648
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• 2008

Purpose: The aim of this study was to investigate the clinical cases of subcondylar fracture with intraoral approach. Material and Method: Fifteen patients with unilateral subcondylar fracture were treated in the department of oral and maxillofacial surgery, Kangdong Sacred Heart Hospital, College of Medicine, Hallym University between 2006 and 2007. Each patients was examined by computed tomography(CT) and panorama. 3D-CT taken when fractured segment was displaced and comminuted. Patients was done intermaxillary fixation to occlusal stability and prevent displacement of fractured segment before general operation. Open reduction and internal fixation(ORIF) accomplished under general anesthesia and used to intraoral approach. We examinated the state of occlusion, maximum opening. Evaluation of the state of occlusion was divided in patient`s subjective evaluation that compare pre-traumatic occlusion with postoperative occlusion, and estimator`s objective evaluation that use articulating paper. Examination was done at 2 weeks, 1, 3, 6 month postoperative by follow up. Result: The ORIF through intraoral approach was good in all patients. In the state of occlusion, all patients recovered pre-traumatic occlusion in 6 month postoperation. Maximum opening was gradually increased. In 3 month postoperative, maximum opening was excessed 40mm. Conclusion: Our study indicate that the intraoral approach is a good technique for subcondylar fracture. Intraoral approach prevent complication that facial nerve damage, scar formation caused by extraoral approach. So, we recommend intraoral approach when subcondylar fracture.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제27권6호
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• pp.556-559
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• 2001

The aim of the present study was to evaluate the influences of epinephrine and pain on the changes of blood pressure and pulse rates in mandibular 3rd molar extraction. A total of 80 patients(aged between 10 and 30) without systemically compromised conditions were selected and divided into two groups(I, II). 2% lidocaine with 1:100,000 epinephrine was administered in group I (male 20, female 20), and 2% lidocaine without epinephrine was administered in group II (male 20, female 20). Systolic blood pressure and pulse rates were checked by a digital monitor during the pre-local anesthesia state(stage 1), 5 minute later in the post-local anesthesia state(stage 2), the extraction state(during odontectomy, stage 3), and during the post-suture state(stage 4). The measurement of pain perceived by patients was made using a three-point visual analog scale. The results suggest that local anesthetic with epinephrine is better at decreasing pain preventing the severe elevation of systolic blood pressure than local anesthetic without epinephrine. However, these results should be confirmed by additional studies on cardiac patients.

• 한국치위생학회지
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• 제7권2호
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• pp.177-187
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• 2007

The purpose of this study was to examine whether dating affected young people's concern for their looks and their oral health state, and to motivate students to promote their oral health, as national oral health depended on students who would grow into eligible members of society in the near future. Relevant literature and data were reviewed, and a survey was conducted on residents in and around Seoul, who were in their 20s, for approximately three months from June through August 2006 to find out about their oral health status. The findings of the study were as follows: 1. Whether they were seeing someone or not was investigated, and it's found that 37.5 percent had a girl friend or boy friend, and that 6.7 percent hadn't. 2. Concerning the state of dating, 40.3 percent, the largest percentage, had been dating for less than a year, and the largest number of them that accounted for 23.6 percent had been dating one person till then, 4.0 percent were considering getting married with those whom they were seeing. The most dominant type of love was eros(romantic or ardent love; 41.7%), followed by stroge(friendly love; 33.3%), and agape(altruistic, devoted love; 12.5%). 3. As for the impact of dating on oral health status, those who were seeing someone were similar to those who weren't in toothbrushing frequency, toothbrushing time and simplified oral hygiene index. There was no significant gap between the two. 4. Concerning the influence of dating on dental-treatment experience, no statistically significant intergroup differences were found in experiences of taking dental-caries treatment, bad-breath treatment and teeth-whitening treatment. There was a statistically significant intergroup gap only in scaling experience(pE0.05). 5. Regarding the impact of dating on oral health care, 59.7 percent of those who were dating thought that it affected oral health care, and the same rate of the others who weren't stood at 38.3 percent. There was a statistically significant gap between the two(pE0.01). 6. As to the influence of general characteristics on oral hygiene index, their age and gender made no statistically significant differences to that. By occupation, however, many of the company employees were in good oral health, and many of them were in bad oral health, too. The office workers were statistically significantly different from the others in that regard(pE0.01).

• 치위생과학회지
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• 제9권4호
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• pp.475-483
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• 2009

한국 노인을 대상으로 외국에서 비교적 높은 신뢰도와 타당도가 입증된 Oral Health Impact Profile 14(OHIP 14)를 한국의 문화적 특성이나 사고방식에 맞게 번역하여 강릉시에 거주하는 노인 만 65세 이상 668명을 대상으로 2005년 1월부터 2월까지 2개월간 OHIP 14 지표의 신뢰도와 타당도를 검증(Kappa index, Cronbach's alpha Correlation & Spearman ranked correlation coefficient)하고, OHIP 14와(구강)건강인식도, 구강건강상태, 전신건강 상태와의 차이를 검증(Kruskal Wallis test, Mann-Whitney U-test)함으로써, 향후 우리나라 노인 구강건강문제를 포괄적으로 파악하기 위한 지표로 활용할 수 있는 지를 검토하고자 하였다. 1. (구강)건강인식도와 OHIP 14는 전신건강인식도, 구강건강인식도, 치과치료필요도, 구강건강만족도, 통증에 대한 시각적 정도, 틀니만족도, 구강건강상태와 OHIP 14는 무치악 여부, 현존 자연치아의 개수, 치아치료필요, 전신건강상태와 OHIP 14는 질병의 개수, 치매, 눈, 귀, 호흡기, 심혈관, 소화기, 비뇨생식기, 근골격계, 신경계, 심리상태가 상관관계가 있는 것으로 나타났다. 2. (구강)건강인식도에 따른 OHIP 14는 전신건강인식도, 구강건강인식도, 치과치료필요도, 구강건강만족도, 통증에 대한 시각적 정도, 틀니만족도, 구강건강상태에 따른 OHIP 14는 무치악 여부, 치아치료필요, 현존 자연치아의 개수, 전신건강상태에 따른 OHIP 14는 치매, 귀, 호흡기, 심혈관, 소화기, 근골격계, 신경계, 심리상태에서 현저한 차이를 보였다. 본 연구는 일부 노인에서 임상지표를 이용한 OHIP 14에서 (구강)건강인식도, 구강건강상태, 전신건강상태가 OHIP 14와의 타당도와 연관성이 있다는 사실을 일부에서 확인할 수 있었다. 이상의 결과로 향후 한국노인의 구강건강문제를 포괄적으로 파악하는데 전통적인 구강건강 상태검사, 전신건강상태검사와 더불어 '구강건강 관련 삶의 질' 지표인 OHIP 14를 활용할 수 있을 것으로 사료된다.

• BMB Reports
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• 제48권3호
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• pp.147-152
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• 2015

Small interfering RNA (siRNA) functions through pairing with specific mRNA sequences and results in the mRNA's degradation. It is a potential therapeutic approach for many diseases caused by altered gene expression. The delivery of siRNA is still a major problem due to its rapid degradation in the circulation. Various strategies have been proposed to help with the cellular uptake of siRNA and short or small hairpin RNA (shRNA). Here, we reviewed recently published data regarding local applications of siRNA. Compared with systemic delivery methods, local delivery of siRNA/shRNA has many advantages, such as targeting the specific tissues or organs, mimicking a gene knockout effect, or developing certain diseases models. The eye, brain, and tumor tissues are 'hot' target tissues/organs for local siRNA delivery. The siRNA can be delivered locally, in naked form, with chemical modifications, or in formulations with viral or non-viral vectors, such as liposomes and nanoparticles. This review provides a comprehensive overview of RNAi local administration and potential future applications in clinical treatment.