• The Journal of Advanced Prosthodontics
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• 제14권6호
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• pp.369-378
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• 2022

PURPOSE. The purpose of this in vitro study was to assess whether scanning strategies of virtual interocclusal record (VIR) affect the accuracy of VIR during intraoral scanning. MATERIALS AND METHODS. Five pairs of reference cubes were added to the digital upper and lower dentitions of a volunteer, which were printed into resin casts. Subsequently, the resin casts were articulated in the maximal intercuspal position in a mechanical articulator and scanned with an industrial computed tomography system, of which the VIR was served as a reference VIR. The investigated VIR of the upper and lower jaws of the resin master cast were recorded with an intraoral scanner according to 9 designed scanning strategies. Then, the deviation between the investigated VIRs and reference VIR were analyzed, which were measured by the deviation of the distances of six selected reference points on the upper reference cubes in each digital cast to the XY-plane between the investigated VIRs and reference VIR. RESULTS. For the deviation in the right posterior dentitions, RP group (only scanning of right posterior dentitions) showed the smallest deviation. Besides, BP group (scanning of bilateral posterior dentitions) showed the smallest deviation in the left posterior dentitions. Moreover, LP group (scanning of left posterior dentitions) showed the smallest deviation in the anterior dentitions. For the deviation of full dental arches, BP group showed the smallest deviation. CONCLUSION. Different scanning strategies of VIR can influence the accuracy of alignment of virtual dental casts. Appropriate scanning strategies of VIR should be selected for different regions of interest and edentulous situations.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제37권3호
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• pp.241-244
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• 2011

Introduction: Intravenous sedation is performed to ensure smooth and safe surgery. Dental anxiety is a reaction to an unknown danger. The Spielberger's state-trait anxiety inventory (STAI) can be used to simultaneously evaluate the levels of state and trait anxiety. State anxiety is defined as subjective feelings of nervousness. This study assessed the presurgical anxiety using STAI and performed intravenous sedation for patients whose level of state anxiety was > stage IV. Based on our clinical experience, it is believed that higher doses of sedatives are needed to induce the desired levels of sedation in patients with a high level of state anxiety. Objectives: This study examined whether the sedative consumption of the patient with a high anxiety level increased. Patients and Methods: Patients with state anxiety scores of ${\geq}$51 were included in Group V, and those with state anxiety scores ranging from 42 to 50 were placed in Group IV. To induce sedation, intravenous access was established, and a bolus dose of 3.0 mg midazolam was administered intravenously. Sedation was maintained by administering a continuous infusion of propofol, which was aimed at achieving an Observer's Assessment of Alertness/Sedation scale of 10-12/20. In this study, midazolam was initially administered when the body movements appeared to occur or the blood pressure increased. This was followed by the administration of higher doses of propofol if low sedation was observed. Results: There were no significant differences in the patient demographics, duration of sedation, and doses of local anaesthetic agents between Groups IV and V. The midazolam dose and mean propofol dose needed to maintain comparable levels of sedation were significantly higher in Group V than in Group IV. Conclusion: In female patients, whose level of preoperative state anxiety is more than Stage V of STAI, a large quantity of sedatives is needed for intravenous sedation.

• 한국치위생학회지
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• 제11권4호
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• pp.499-509
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• 2011

Objectives : The purpose of this study was to provide some information on down-to-earth oral health policy to improve the systemic health involving oral health and the quality of life in Korean adults. Methods : The third-year data of the 4th National Health and Nutrition Survey in 2009 were analyzed, and $x^2$(Chi-square) test was carried out to see whether there would be any gaps in subjective oral health status according to demographic characteristics, systemic health state, frequency of eating between meals and oral health behavior. In terms of the DMFT index, one-way ANOVA was utilized, and then Scheffe post-hoc analysis was conducted. Besides, multiple regression analysis was made to grasp the relationship of oral health behavior to subjective oral health state and the DMFT index. Results : The demographic characteristics, systemic health status and oral health behavior had a significant relationship to both of subjective oral health status and the DMFT index. As a result of analyzing the relationship of oral health behavior to subjective oral health state and the DMFT index, the subfactors of oral health behavior exerted a significant independent influence on subjective oral health status and the DMFT index. Conclusions : The findings of the study suggest that in order to promote the oral health of adults, preventive measures should be taken, and systematic oral health education should be provided. As there is an increase in the elderly population in Korea, the successful implementation of senior oral health plans and the development of oral health programs geared toward adults are both required.

• 치위생과학회지
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• 제11권4호
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• pp.305-310
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• 2011

50대 이상 장 노년층 성인들의 구강건강 관련 삶의 질(Oral-health related quality of life, OHRQoL)과 건강 결과(health outcome)의 관련성을 평가하기 위해 148명을 편의추출하여 구강검사와 면접조사를 통해 OHIP-14(Oral health impact profile-14)와 인지 건강 및 구강건강 상태를 측정하고, 독립표본 t 검정, 일원분산분석, 교차분석, 상관분석 등을 실시한 결과 다음과 같은 결론을 얻었다. 1. OHIP-14의 모든 문항에 대해 조사 대상자 중 9.5%가 전혀 문제나 불편감을 느끼지 않는다고 응답하였으며, 가장 문제를 많이 느끼는 차원은 '신체적 통증'(69,8%)과 '심리적 불편감'(63.5%)으로 나타났다. 2. 평가 구강건강 상태에 따른 구강건강 관련 삶의 질 수준을 비교한 결과 우식경험치아수, 잔존치아수에 따라 유의한 차이가 나타났으나(p=0.045), 치주상태와 틀니사용여부에 따른 차이는 나타나지 않았다. 3. 조사 대상자의 43.9%(N=65)가 자신이 '건강하지 않다'고 느끼고 있으며, 43.9%(N=65)가 자신의 구강건강상태가 '나쁘다'고 생각하고 있고, 54.7%(N=81)가 자신의 구강건강상태에 대해 '만족하지 않는다'고 응답했다. 4. 조사 대상자가 느끼는 인지 건강상태에 따른 구강건강 관련 삶의 질을 비교한 결과 인지 건강상태, 인지 구강건강상태, 구강건강 만족도에 따라 유의한 차이가 나타났다(p<0.001). 5. 조사 대상자의 인지 건강상태와 OHIP-14 점수는 유의한 상관관계가 있으나(r=0.326, p<0.01), 인지 건강상태와 우식경험치아수, 잔존치아수의 상관관계는 통계적으로 유의하지 않았다.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제41권3호
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• pp.133-138
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• 2015

Objectives: To evaluate the influence of the type of osteotomy in the inferior aspect of the mandible on the mechanical performance. Materials and Methods: The study was performed on 20 polyurethane hemimandibles. A sagittal split ramus osteotomy (SSRO) was designed in 10 hemimandibles (group 1) with a vertical osteotomy in the buccal side (second molar level) and final osteotomy was performed horizontally on the lingual aspect, while the mandible body osteotomy was finalized as a straight osteotomy in the basilar area, perpendicular to the body. For group 2, the same osteotomy technique was used, but an oblique osteotomy was done in the basilar aspect of the mandibular body, forming continuity with the sagittal cut in the basilar area. Using a surgical guide, osteosynthesis was performed with bicortical screws using an inverted L scheme. In both groups vertical compression tests were performed with a linear load of 1 mm/min on the central fossa of the first molar and tests were done with models made from photoelastic resin. Data were analyzed using Student's t-test, establishing a statistical significance when P<0.05. Results: A statistical difference was not observed in the maximum displacements obtained in the two osteotomies (P<0.05). In the extensiometric analysis, statistically significant differences were identified only in the middle screw of the fixation. The photoelastic resin models showed force dissipation towards the inferior aspect of the mandible in both SSRO models. Conclusion: We found that osteotomy of the inferior aspect did not influence the mechanical performance for osteosynthesis with an inverted L system.

• Journal of Ginseng Research
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• 제47권6호
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• pp.694-705
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• 2023

Panax ginseng Meyer is a traditional Chinese medicine that is widely used as tonic in Asia. The main pharmacologically active components of ginseng are the dammarane-type ginsenosides, which have been shown to have anti-cancer, anti-inflammatory, immunoregulatory, neuroprotective, and metabolic regulatory activities. Moreover, some of ginsenosides (eg, Rh2 and Rg3) have been developed into nutraceuticals. However, the utilization of ginsenosides in clinic is restrictive due to poor permeability in cells and low bioavailability in human body. Obviously, the dammarane skeleton and glycosyls of ginsenosides are responsible for these limitations. Therefore, improving the oral bioavailability of ginsenosides has become a pressing issue. Here, based on the structures of ginsenosides, we summarized the understanding of the factors affecting the oral bioavailability of ginsenosides, introduced the methods to enhance the oral bioavailability and proposed the future perspectives on improving the oral bioavailability of ginsenosides.

• 한국치위생학회지
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• 제9권4호
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• pp.836-848
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• 2009

Objectives : This study was conducted to evaluated the subjective oral health state related periodontal disease of elderly people. Methods : Data were collected through the National Health and Nutrition Survey in 2005. Participants consisted of 1,091 elderly people above 65 years old. Independent variables in the survey were social characteristic, health behavior, oral health condition, oral health management. The data were analyzed by using the SPSS 12.0. Results : The more elderly people of 69.0% recognized own oral health as is not healthy, elderly people of 74.0% recognized own oral health as is not healthy about subjective oral health and a lot of stressed(82.8%) has felt highly about periodontal disease(p<0.001). Respondents of have a sound teeth(58.9%), have a lower denture(75.0%) and have a no problem in mastication(74.5%) has felt highly about periodontal disease(p<0.001). Elderly people recognized own oral health as is not healthy about subjective oral health were 0.316 times(p<0.01), elderly people recognized own oral health as is common healthy about subjective oral health were 0.241 times(p<0.001), a lot of stressed were 1.410 times has felt highly about periodontal disease. Elderly people of have a lower denture were 1.159 times, have a upper denture were 1.159 times, have a lower and upper denture were 0.464 times has felt highly about periodontal disease(p<0.05). Also respondents of have a no problem in mastication were 7.464 times compared with problem in mastication(p<0.001). Conclusions : Quality of life from disease of Korean elderly people can be fallen, and improve quality of life that medical treatment is healthy numerical value state numerical value state. Study's findings of above may be used to inform the importance of health numerical value state while establish dental health policy that is string.

• International Journal of Stem Cells
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• 제16권2호
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• pp.180-190
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• 2023

Background and Objectives: Regenerative endodontic procedures (REPs) are a research hotspot in the endodontic field. One of the biggest problems of REPs is that it is difficult to realize regeneration of pulp-dentin complex and functional reconstruction. The reason is still not clear. We hypothesize that the migration may be different in different dental stem cells. Periodontal ligament stem cells (PDLSCs) may migrate faster than stem cells of apical papilla (SCAPs), differentiating into cementum-like tissue, bone-like tissue and periodontal ligament-like tissue and, finally affecting the outcomes of REPs. Hence, this study aimed to explore the mechanism that regulates the migration of PDLSCs. Methods and Results: After isolating and culturing PDLSCs and SCAPs from human third molars, we compared the migration of PDLSCs and SCAPs. Then we investigated the role of SDF-1𝛼-CXCR4/CXCR7 axis in PDLSC migration. We further investigated the impact of Porphyromonas gingivalis (P. gingivalis) lipopolysaccharide (LPS) on PDLSC migration and the potential mechanism. PDLSCs showed better migration under both noninflammatory and inflammatory conditions than SCAPs. SDF-1𝛼 can promote the migration of PDLSCs by elevating the expression of CXCR4 and CXCR7, increasing the interaction between them, promoting expression of 𝛽-arrestin1 and activating the ERK signaling pathway. P. gingivalis LPS can promote the migration of PDLSCs toward SDF-1𝛼 through increasing the expression of CXCR4 via the NF-𝜅B signaling pathway, promoting the expression of 𝛽-arrestin1, and activating the ERK signaling pathway. Conclusions: This study helped elucidate the potential reason for the difficulty in forming pulp-dentin complex.

• 한국치위생학회지
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• 제6권4호
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• pp.295-309
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• 2006

This study was conducted among 831 industrial workers in Gumi City in Gyung-Sang-Buk Do for the purpose of acquiring knowledge to improve quality of life though industrial workers' oral health promotion. Oral examination and questionnaire surveying were used to evaluate workers' oral health state and subjective health state and analyze their effect on quality of life. 1. The number of workers in the study were 831 in all; there were more males who accounted for 74.6%. 43.7% of the subject were 29 years old, accounting for the largest age group. Their academic backgrounds are 53.6% workers who graduated from high schools or lower educational institutions, and 46.4% workers who graduated from college or higher educational institutions. 80.7% of the subjects replied that their economic state belonged to the middle class. Their job classification indicates that 70.2% were working in production and engineering fields and that the seniority of 55.3% workers was less than 55.3%. 2. The result of evaluating the effects of oral health state on individual well-being and quality of life using OHIP indicates that younger people, singles(p<0.01) than the married, those in worse economic situation and those with shorter seniority(p<0.01) had higher effect of oral health state on quality of life. In addition, those whose health or oral health was not good (p<0.01), those with liked tough texture of food and snacks(p<0.05), those with more frequency of drinking(p<0.01) and those with more smoking tended to have higher effect of oral health state on daily life or quality of life. Besides, OHIP confirmed that oral health state is a measurement tool that can evaluate its effect on individual well-being and quality of life. The suggestion for future studies is to develop Korean style OHIP that can be used conveniently and efficiently by expanding the subject area up to the whole country and validating the samples gained from random sampling.

• Imaging Science in Dentistry
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• 제50권2호
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• pp.141-151
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• 2020

Purpose: This study aimed to quantify the influence of tooth position within the field-of-view (FOV) on cone-beam computed tomography (CBCT) imaging artifacts' intensity when assessing teeth restored with various intracanal materials. Materials and Methods: Seventy single-rooted teeth were divided into 7 groups (10 teeth per group): NiCr post (NC), AgPd post (AP), metal core fiberglass post (MCFG), fiberglass post (FG), anatomical fiberglass post (AFG), fiberglass post cemented with core build-up cement (FGCo), and anatomical fiberglass post cemented with core build-up cement (AFGCo). All posts were cemented using a regular dual-curing resin cement (Allcem), except FGCo and AFGCo which were cemented with a core build-up dual-curing resin cement (AllcemCore). Each tooth was scanned on a CS9000 in 5 positions within the FOV: a central position, anterior horizontal peripheral, peripheral superior, peripheral inferior, and posterior horizontal peripheral position. Hyperdense, hypodense, remaining teeth areas and ROI areas were quantitatively analyzed using ImageJ software. Results: Posterior horizontal peripheral position increased the intensity of artifacts on FGCo and AFGCo post groups (P<0.05), and specifically the hypodense artifact intensity on FG and AFG post groups (P<0.05). NC and AP groups presented greater intensity of artifacts than any other post groups(P<0.05). Conclusion: Artifact intensity increases in the presence of high atomic number materials and when the object is not centered within the FOV. The impact of positioning within the FOV on artifact was greater for fiberglass posts cemented with core build-up dual-curing cement than for metal posts and fiberglass posts cemented with regular dual-curing cement.