• 생명과학회지
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• 제9권3호
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• pp.241-247
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• 1999

Antibiotics have been routinely used to control the disease of farm-raised animals in the aquaculture facilities without any criterion based on a pharmacokinetic study. This lack of information on the effective usage of antibiotics would have brought the farmers to use excessive and/or less dosages, causing the advent of drug-resistant bacteria as well as economic loss and possible contamination of the local farming area. Until recently, few studies on a detailed manual for the antibiotic usage including chemotherapy procedure, dosage, and treatment schedule of the aquatic antibiotics have been conducted throughout the world. To the worse, there is no available criterion for optimal usage of aquatic antibiotics to control diseases in aquatic farms in this country because every country has its own aquacultural system. Therefore, based on the previous studies on the usage of the various antibiotics, our studies are to focus on the development of optimal method for the detection of various antibiotics on the fate of antibiotics applied to the fish, including absorption, circulation, and secretion physiology. Pharmacokinetic study were to sep up the optimal detective condition against residual antibiotics of fish by HPLC. The grinding pefloxacin for 15 min is most effective in dissolution test and pharmacokinetic parameters. Pharmacokinetic parameters were satisfactory for 15 min-grinding products and they can be explained as one-compartment model.

• 한국해양공학회지
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• 제17권6호
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• pp.16-22
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• 2003

In this paper, the method of determining the economically-optimal design section of rubble mound breakwater, using ADS program, was studied to supplement the deterministic approach. First of all, the design waves are computed, according to the return periods, using the Weibull distribution from the data of waves at the location of the breakwater. In order to take an optimal section, according to the return periods, the ADS program was used. The restriction conditions and objective functions are decided from the references of the specifications and standard manuals for Coastal and Harbor Construction Work. Results from this study support the ADS program as an appropriate method for determining the economically-optimal section of rubble mound breakwater, comparing the construction costs and the initial and damage repair costs for its life time.

• International Journal of Precision Engineering and Manufacturing
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• 제6권1호
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• pp.42-50
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• 2005

In order to increase competitiveness and to gain economic benefit, companies ask more and more how to recycle their products in an efficient way. So far, to answer this question, companies are not sufficiently supported by suitable methods specially in the area of disassembly process planning. For this reason, we develop in collaboration with an industrial partner a new method for generating an optimal disassembly sequence. In this paper this method will be described in detail by considering the exiting assembly information, disassembly method and disassembly depth. PLM(Profit-Loss Margin) curve that is used to determine disassembly depth consists of profit value, disassembly cost and disassembly effect. Using assessment parameters, generated alternative disassembly sequences are evaluated and an optimal disassembly sequence is proposed. This method is applied to generate the optimal disassembly sequence of Door Trim as an example.

• KEPCO Journal on Electric Power and Energy
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• 제3권1호
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• pp.23-28
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• 2017

The life management technology becomes important as the failure risk of the aged power transformers increases. Asset management technology, therefore, has been developed to evaluate the remaining life and build replacement strategies of power transformers, which enables an optimal investment decisions based on reliability and economic feasibility. The remaining life assessment technology uses data related to such as installation, operation, maintenance, refurbishment, and disposed history of power transformers. The optimal investment decision additionally uses data related to failure and social costs. To develop the asset management technology in power transformers, it is important to find deterioration parameters directly indicating degradation of power transformers. In this study, 110,000 DGA data during the past 35 years have been analyzed in order to find the deterioration parameters related to the degradation of power transformers. The alarm rates of combustible gases ($H_2$, $C_2H_2$, $C_2H_4$, $CH_4$, $C_2H_6$), TCG CO, and $CO_2$ were analyzed as deterioration parameters. The origin of the gas was discussed in connection with discharge, overheating and insulation aging.

• KIEAE Journal
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• 제15권4호
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• pp.37-43
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• 2015

Purpose : The study applied control strategy to reduce through optimal control and operation of pump by applying control on variable speed to the circulation pump of HVAC system in the office building. The study has the purpose to review validity of control on variable speed as ESMs(Energy Saving Measures) and establish the control technology on variable speed pump. The study performed reduction analysis of building energy and economic evaluation of pump through energy effectiveness control strategy of HVAC system. Method: The study sought possible reduction through energy control strategy which can provide proper flow fitting to building load by applying control on variable speed pump. The study applied control strategy to reduce through pressure differential set-point control and operation of pump by applying control on variable speed to the circulation pump of HVAC system in the office building. Result : The results showed that about 16-35% of pump energy could be saved by using these optimal control strategies. In the result of analysis on 10 years life cycle cost of analysis on payback period of initial investment pump, variable speed pump control showed 5.1 years.

• 한국조리학회지
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• 제14권3호
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• pp.196-209
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• 2008

This study was conducted to mass-produce brown stock optimized by using a high-pressure heating extractor and to use brown stock as a material for developing various products. For these purposes, we attempted to produce standardized brown stock by extracting brown stock using a high-pressure heating extractor and compared it with brown stock extracted by the traditional method in terms of general elements and mechanical and sensory characteristics. With regard to how to prepare optimal brown stock, the best brown stock was that extracted seven times repeatedly by the traditional method, but the method had a large economic loss in terms of material consumption and took a long time in extraction. Thus, considering time and labor, it was concluded that extraction at 120$^{\circ}C$ for 15 hours using a high-pressure heating extractor is the optimal extraction condition in terms of economic efficiency and quality. The results of this study are expected to be useful as a practical material for making brown stock production process more convenient, applying cooks' traditional cooking techniques to mass production, maintaining standardized superior quality and taste, and improving shelf life.

• 환경정책연구
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• 제9권2호
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• pp.41-55
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• 2010

댐은 사회전반에 걸쳐 많은 편익을 제공하고 있다. 이를 위해서는 일정수준 이상의 저수용량 확보가 필수적이다. 그러나 상류의 토사 유입으로 인하여 댐의 저수용량은 줄어들고 있는 실정이다. 전 세계적으로 5조 톤의 토사가 매년 댐 뒤에 쌓이는 실정이다. 강이 여러 지역에 걸쳐 흐르는 경우 상류의 농업에서 발생하는 토사는 장시간에 걸쳐서 지속적으로 발생하기 때문에 상류 농업종사자들은 관리를 소홀히 하는 경향이 있다. 특히 토사는 댐의 저수용량을 지속적으로 줄여 궁극적으로는 댐의 경제적 가치를 소멸시키는 효과가 있다. 따라서 상류 지역의 토사저감 노력과 함께 댐의 저수용량 확보가 급선무이다. 실증분석으로 나일강 상류의 수단 농업지역과 하류의 이집트 Aswan High Dam을 분석하였다. 실증분석 결과 상류 농업부문의 토사저감 노력과 댐의 토사제거 방안이 사회전체의 경제적 편익을 극대화하는 것으로 나타났다. 동태적 최적제어이론을 이용한 유역토사관리 모형에서 댐의 경제적 편익을 포함한 사회전체의 편익은 크게는 약 1,510억 달러로 추산되었다.

• 한국전산구조공학회:학술대회논문집
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• 한국전산구조공학회 1999년도 가을 학술발표회 논문집
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• pp.249-256
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• 1999

This study is intended to propose a systematic procedure for the development of the reliability-based seismic safety and cost-effective Performance criteria for design and upgrading of long span PC bridges. In the paper, a set of cost function models for life cycle cost analysis of bridges is proposed. The total life cycle cost functions consist of initial cost and direct/indirect damage costs considering repair/replacement costs, human losses and property damage costs, road user costs, and indirect regional economic losses. The damage costs are successfully expressed in terms of Park-Ang median global damage indices and damage probabilities. The proposed approach is successfully applied to model bridges in both regions of a moderate seismicity area like Seoul, Korea and a high one like Tokyo, Japan. It may be expected that the proposed approach can be effectively utilized for the development of cost-effective performance criteria for design and upgrading of various types of bridges as well as long span PC bridges.

• Journal of Korean Neurosurgical Society
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• 제66권1호
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• pp.6-11
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• 2023

Spinal cord injury (SCI) has a significant negative effect on the quality of life due to permanent neurologic damage and economic burden by continuous treatment and rehabilitation. However, determining the correct approach to ensure optimal clinical outcomes can be challenging and remains highly controversial. In particular, with the introduction of the concept of early decompression in brain pathology, the discussion of the timing of decompression in SCI has emerged. In addition to that, the concept of "time is spine" has been added recently, and the mortality and complications caused by SCI have been reduced by providing timely and professional treatment to patients. However, there are many difficulties in establishing international clinical guidelines for the timing of early decompression in SCI because policies for each country and medical institution differ according to the circumstances of medical infrastructure and economic conditions in the surgical treatment of SCI. Therefore, we aim to provide a current review of timing of early decompression in patient with SCI.

• 한국지열·수열에너지학회논문집
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• 제8권3호
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• pp.12-18
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• 2012

The purpose of this study is to make an economic analysis(Life cycle cost) of selecting optimal air conditioning system for a research building which is 8 stories with a total floor area of $32,010m^2$. Energy consumptions of three proposed air-conditioning systems(Alt-1,2,3) that reflect the government green-growth policy are calculated and compared. The results show that life cycle cost of Alt-3(Ventilation DX AHU+EHP) is less than Alt-1(EHP+ventilation DX AHU) by 5.1%, and Alt-2(Absorption chiller/heater+EHP) by 34.3%. Annual energy consumption of Alt-3 is less than Alt-1 by 9.9%, and Alt-2 by 37.4%. Annual $CO_2$ emission of Alt-3 is less than Alt-1 by 9.9%, and Alt-2 by 0.2%.