• Title/Summary/Keyword: Optimal Size

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Effect of optimal sodium stearoyl-2-lactylate supplementation on growth performance and blood and carcass characteristics in Hanwoo steers during the early fattening period

  • Lee, Shin Ja;Lee, Sang Suk;Kim, Eun Tae;Jeong, Jin Suk;Lee, Ji Hoon;Jeong, Joon;Park, Joong Kook;Park, Beom Young;Jeong, Ha Yeon;Ki, Kwang Seok;Kim, Chang Hyun;Lee, Sung Sill
    • Asian-Australasian Journal of Animal Sciences
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    • v.31 no.9
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    • pp.1442-1448
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    • 2018
  • Objective: This study was conducted to evaluate the effect of different levels of total digestible nutrients (TDN) and sodium stearoyl-2-lactylate (SSL) supplementation on growth performance and blood and carcass characteristics in Hanwoo steers during the early fattening period. Methods: Sixty Hanwoo steers (average body weight, $333{\pm}36.4kg$) were randomly allotted to 3 treatments, with twenty steers per treatment, and ten steers per pen with a size of $80m^2$. Dietary treatments were as follows: CON, basal diet; treatment (TRT) 0.5, 0.5% down-spec of TDN with 0.1% SSL; TRT 1.0, 1.0% down-spec of TDN with 0.1% SSL. Results: The results demonstrated that average daily gain and feed efficiency increased with TRT 0.5 (0.85 kg and 11.68) vs CON (0.82 kg and 11.27) or TRT 1.0 (0.78 kg and 10.74), indicating that 0.1% SSL supplementation in the feed of early fattening steers may result in a saving of 0.5% TDN. No significant differences were observed amongst all treatments (p>0.05) for blood metabolite concentration and blood corpuscle values, which were all within the normally accepted range for healthy steers. Conclusion: Our study suggests that a TDN 0.5% down spec with 0.1% SSL supplemented feed may be effective and profitable for the early fattening period of Hanwoo steers without causing adverse effects.

A New Inflammatory Prognostic Index, Based on C-reactive Protein, the Neutrophil to Lymphocyte Ratio and Serum Albumin is Useful for Predicting Prognosis in Non-Small Cell Lung Cancer Cases

  • Dirican, Nigar;Dirican, Ahmet;Anar, Ceyda;Atalay, Sule;Ozturk, Onder;Bircan, Ahmet;Akkaya, Ahmet;Cakir, Munire
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.12
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    • pp.5101-5106
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    • 2016
  • Purpose: We aimed to establish an inflammatory prognostic index (IPI) in early and advanced non-small cell lung cancer (NSCLC) patients based on hematologic and biochemical parameters and to analyze its predictive value for NSCLC survival. Materials and Methods: A retrospective review of 685 patients with early and advanced NSCLC diagnosed between 2009 and 2014 was conducted with collection of clinical, and laboratory data. The IPI was calculated as C-reactive protein ${\times}$ NLR (neutrophil/ lymphocyte ratio)/serum albumin. Univariate and multivariate analyses were performed to assess the prognostic value of relevant factors. Results: The optimal cut-off value of IPI for overall survival (OS) stratification was determined to be 15. Totals of 334 (48.8%) and 351 (51.2%) patients were assigned to high and low IPI groups, respectively. Compared with low IPI, high IPI was associated with older age, greater tumor size, high lymph node involvement, distant metastases, advanced stage and poor performance status. Median OS was worse in the high IPI group (low vs high, 8.0 vs 34.0 months; HR, 3.5; p<0.001). Progression free survival values of the patients who had high vs low IPI were determined 6 months (95% CI:5.3-6.6) and 14 months (95% CI:12.1-15.8), respectively (HR; 2.4, P<0.001). On multivariate analysis, stage, performance status, lactate dehydrogenase and IPI were independent prognostic factors for OS. Subgroup analysis showed IPI was generally a significant prognostic factor in all clinical variables. Conclusion: The described IPI may be an inexpensive, easily accessible and independent prognostic index for NSCLC patients, useful for clinical practice.

Determination of Tumor Volume in PET for the Radiation Treatment Planning: Computer Simulation (방사선치료계획을 위한 PET 종양용적 결정 연구: 컴퓨터 모의실험)

  • Yoon Seok Nam;Joh Chul-Woo;Lee Jae Sung
    • Progress in Medical Physics
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    • v.16 no.4
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    • pp.183-191
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    • 2005
  • The utilization of PET has been increased so fast since the usefulness of the PET has been proved in various clinical and research fields. Among the many applications, the PET Is especially useful in oncology and most of the clinical PET scans are peformed for the oncologic examination Including the different diagnosis of malignant and benign tumors and assessment of the treatment effects and recurrent tumors. As the PET-CT scanners are widely available, there is Increasing interest in the application of the PET Images to the radiation treatment planning. Although the CT images are conventionally used for the target volume determination in the radiation treatment planning, there are fundamental limitation In use of only the anatomical information. Therefore, the volume determination of the functionally active tumor region using the PET would be important for the treatment planning. However, the accurate determination of the tumor boundary is not simple in PET due to the relatively low spatial resolution of the currently available PET scanners. In this study, computer simulations were peformed to study the relationship between the lesion size, PET resolution, lesion to background ratio and the threshold of Image Intensity to determine the true tumor volume.

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A Study on the Cash Policies of Retail Firms (유통 상장기업의 현금정책에 관한 연구)

  • Son, Sam-Ho
    • Journal of Distribution Science
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    • v.13 no.3
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    • pp.69-77
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    • 2015
  • Purpose - The purpose of this study is to examine whether the cash policies of retail firms listed on Korean stock markets are consistent with the evidence provided in the study of Almeida et al. (2004). Liquidity management is an important issue for financially constrained firms relative to financially unconstrained firms. Because there are few sources of external funding, the optimal liquidity policies of financially constrained firms should reflect their own earnings or cash inflows to create opportunities for current and future real investments. According to this simple idea, we estimate the sensitivity of cash to cash flows and simply check whether the estimated sensitivity to cash flows of the cash retained by constrained retail firms is greater than that of the cash retained by unconstrained retail firms. Through this work, we aim to explain why the cash policies of the retail firms listed on the Korean stock markets differ from those of listed manufacturing enterprises. Research design, data, and methodology - To explain a firm's cash holdings, we use only three explanatory variables: earnings before interest and taxes (EBIT), Tobin's q, and size. All the variables are defined as the value of the numerator divided by aggregate assets. Thanks to this definition, it is possible to treat all the sample firms as a single large firm. The sample financial data for this study are collected from the retail enterprises listed on the KOSPI and KOSDAQ markets from 1991 to 2013. We can obtain these data from WISEfn, the financial information company. This study's methodology has its origin in Keynes's simple idea of precautionary liquidity demand: When a firm faces financial constraints, cash savings from earnings or cash inflows become important from the corporate finance perspective. Following this simple idea, Almeida et al. (2004) developed their theoretical model and found empirical evidence that the sensitivity of cash to cash flows varies systematically according to different types of financing frictions. To find more empirical evidence for this idea, we examined the cash flow sensitivity of the cash held by Korean retail firms. Results - Through several robustness tests, we empirically showed that financially constrained Korean retail firms display significant positive propensity to save cash from earnings before interest and taxes, while the estimated cash flow sensitivity of the cash held by unconstrained retail firms is not significant. Despite the relatively low earnings of retail firms, their sensitivity is three times greater than that of manufacturing enterprises. This implies that Korean retail firms have greater intentions of facilitating future investments rather than current investments. Conclusions - The characteristics of the cash policies of Korean retail firms differ from those of manufacturing firms. This contrast may be attributable to industry-oriented policy planning, regulations, and institutional differences. However, the industrial policymakers should observe signals of the long-term growth options of retail firms based on their high propensity to save from their cash inflows.

Peripheral Dose Distributions of Clinical Photon Beams (광자선에 의한 민조사면 경계영역의 선량분포)

  • 김진기;김정수;권형철
    • Progress in Medical Physics
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    • v.12 no.1
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    • pp.71-77
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    • 2001
  • The region, near the edge of a radiation beam, where the dose changes rapidly according to the distance from the beam axis is known as the penumbra. There is a sharp dose gradient zone even in megavoltage photon beams due to source size, collimator, lead alloy block, other accessories, and internal scatter ray. We investigate dosimetric characteristics on penumbra regions of a standard collimator and compare to those of theoritical model for the optimal use of the system in radiotherapy. Peripheral dose distribution of 6 W Photon beams represents penumbral forming function as the depth. Also we have discussed that the peripheral dose distribution of clinical photon beams, differences between calculation dose use of emperical penumbral forming function and measurements in penumbral region. Predictions by emperical penumbral forming functions are compared with measurements in 3-dimensional water phantom and it is shown that the method is capable of reproduceing the measured peripheral dose values usually to within the statistical uncertainties of the data. The semiconductor detector and ion chamber were positioned at a dmax depth, 5cm depth, 10cm depth, and its specific ratio was determined using a scanning data. The effective penumbra, the distance from 80% to 20% isodose lines were analyzed as a function of the distance. The extent of penumbra will also expand with depth increase. Difference of measurement value and model functions value according to character of the detector show small error in dose distribution of the peripheral dose.

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Process Development for Production of Antioxidants from Lipid Extracted Microalgae Using Ultrasonic-assisted Extraction (탈지미세조류로부터 초음파추출을 이용한 항산화 물질 생산 공정 최적화)

  • Jo, Jaemin;Shin, Suelgl;Jung, Hyunjin;Min, Bora;Kim, Seungki;Kim, Jinwoo
    • Korean Chemical Engineering Research
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    • v.55 no.4
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    • pp.542-547
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    • 2017
  • Ultrasound-assisted extraction (UAE) has attracted growing interest, as it is an effective method for the rapid extraction of bioactive compounds from plants with a high extraction efficiency comparable to the conventional extraction. In this study, UAE was used for the extraction of polyphenols from lipid extracted microalgae (Tetraselmis KCTC 12236BP) and the effects of five extraction variables on the total phenolic compounds (TPC) were studied. For the optimization of extraction parameters, particle size, solid-to-liquid (L/S) ratio, ethanol concentration, extraction temperature and extraction time have been examined as independent variables. All variables exhibited the significant effects on the extraction of TPC and extraction temperature showed the most significant effect among five variables. The optimal extraction conditions were the extraction using mixed particle, S/L ratio of 10%, ethanol concentration of 60%, extraction temperature of $100^{\circ}C$ and extraction time of 30 min, which gave the 8.7 mg GAE/g DW for TPC. Compared with conventional hot-water extraction, TPC extraction under UAE was increased by up to 1.8 fold with same extraction condition. This study showed that UAE under low temperature and short extraction time was proven to be an effective extraction process for TPC production from LEA compared to conventional hot-water extraction process.

A Classified Space VQ Design for Text-Independent Speaker Recognition (문맥 독립 화자인식을 위한 공간 분할 벡터 양자기 설계)

  • Lim, Dong-Chul;Lee, Hanig-Sei
    • The KIPS Transactions:PartB
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    • v.10B no.6
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    • pp.673-680
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    • 2003
  • In this paper, we study the enhancement of VQ (Vector Quantization) design for text independent speaker recognition. In a concrete way, we present a non-iterative method which makes a vector quantization codebook and this method performs non-iterative learning so that the computational complexity is epochally reduced The proposed Classified Space VQ (CSVQ) design method for text Independent speaker recognition is generalized from Semi-noniterative VQ design method for text dependent speaker recognition. CSVQ contrasts with the existing desiEn method which uses the iterative learninE algorithm for every traininE speaker. The characteristics of a CSVQ design is as follows. First, the proposed method performs the non-iterative learning by using a Classified Space Codebook. Second, a quantization region of each speaker is equivalent for the quantization region of a Classified Space Codebook. And the quantization point of each speaker is the optimal point for the statistical distribution of each speaker in a quantization region of a Classified Space Codebook. Third, Classified Space Codebook (CSC) is constructed through Sample Vector Formation Method (CSVQ1, 2) and Hyper-Lattice Formation Method (CSVQ 3). In the numerical experiment, we use the 12th met-cepstrum feature vectors of 10 speakers and compare it with the existing method, changing the codebook size from 16 to 128 for each Classified Space Codebook. The recognition rate of the proposed method is 100% for CSVQ1, 2. It is equal to the recognition rate of the existing method. Therefore the proposed CSVQ design method is, reducing computational complexity and maintaining the recognition rate, new alternative proposal and CSVQ with CSC can be applied to a general purpose recognition.

Segment-based Cache Replacement Policy in Transcoding Proxy (트랜스코딩 프록시에서 세그먼트 기반 캐쉬 교체 정책)

  • Park, Yoo-Hyun;Kim, Hag-Young;Kim, Kyong-Sok
    • The KIPS Transactions:PartA
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    • v.15A no.1
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    • pp.53-60
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    • 2008
  • Streaming media has contributed to a significant amount of today's Internet Traffic. Like traditional web objects, rich media objects can benefit from proxy caching, but caching streaming media is more of challenging than caching simple web objects, because the streaming media have features such as huge size and high bandwidth. And to support various bandwidth requirements for the heterogeneous ubiquitous devices, a transcoding proxy is usually necessary to provide not only adapting multimedia streams to the client by transcoding, but also caching them for later use. The traditional proxy considers only a single version of the objects, whether they are to be cached or not. However the transcoding proxy has to evaluate the aggregate effect from caching multiple versions of the same object to determine an optimal set of cache objects. And recent researches about multimedia caching frequently store initial parts of videos on the proxy to reduce playback latency and archive better performance. Also lots of researches manage the contents with segments for efficient storage management. In this paper, we define the 9-events of transcoding proxy using 4-atomic events. According to these events, the transcoding proxy can define the next actions. Then, we also propose the segment-based caching policy for the transcoding proxy system. The performance results show that the proposing policy have a low delayed start time, high byte-hit ratio and less transcoding data.

Rainfall Distribution Characteristics of Artificial Rainfall System for Steep-Slope Collapse Model Experiment (급경사지 붕괴 모의실험을 위한 인공강우장치의 강우분포특성)

  • Jeong, Hyang-Seon;Kang, Hyo-Sub;Suk, Jae-Wook;Kim, Ho-Jong
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.20 no.12
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    • pp.828-835
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    • 2019
  • An artificial rainfall system is used widely as a research tool for generating model experiment data. Artificial rainfall devices have been used in many studies, but studies of the rainfall distribution are not considered as important issues. To simulate various rainfall characteristics, it should be possible to simulate from low to high intensity, and the homogeneity of the rainfall distribution should be ensured. In this study, the maximum rainfall intensity was set to 130mm/hr and controlled by 10mm/hr. In addition, the aim was to secure a uniform coefficient value of 80% or more. To this end, rainfall tests were performed according to the nozzle type, diameter, position, and pump pressure. The rainfall test showed that the circular nozzle was suitable, and the nozzle size was 1.9mm and 1.4mm. The optimal pump pressure was found to be 3~6kg/㎠. The rainfall intensity tended to increase linearly with increasing pump pressure. Based on the rainfall test results, a rainfall control manual was produced with variables, such as pump pressure, nozzle type, and number of nozzles. As a result of rainfall verification, rainfall intensity showed a 3.1% error with a uniformity coefficient of 86%.

A Study on the Reduction of Waiting Time and Moving Distance through Optimal Allocation of Service Space in a Health Examination Center (건강검진센터의 공간서비스 적정할당을 통한 대기시간 및 이동거리 단축에 관한 연구)

  • Kim, Suk-Tae;Oh, Sung-Jin
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.20 no.12
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    • pp.167-175
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    • 2019
  • Recently, health examination centers have been changing from auxiliary medical facilities to key and independent medical facilities. However, it is not easy to improve medical facilities, including health examination centers, due to the variable characteristics of the relationship between humans and space. Therefore, this study was done to develop a pedestrian-based discrete event simulation analysis program to examine the problems and develop methods for improvement. The program was developed to analyze five evaluation indices and the density of examinees. The problems were derived by analyzing the required time, capacity, and queue size for each examination through simulations. We reduced the examination time and moving distance, increased the capacity, and distributed the queues by adjusting the medical services and relocating the examination rooms. The results were then quantitatively verified by simulations.