• Proceedings of the KSME Conference
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• 2003.04a
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• pp.1609-1614
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• 2003

In this study, a practical holographic interferometric tomography system, which is instantaneous and non-contact for measuring three dimensional flow field, was developed. The system consists of holographic recording/reconstruction system, fringe analysis code and computational tomography code and it is developed with Gill environment for general users. The developed system was applied to three-dimensional natural convection from a discrete flush-mounted circular heat source on the bottom of a cubic enclosure. The heat source was located at the off-center of the bottom plate so that three-dimensional temperature field can be achieved. A set of multi-directional holographic interferograms was recorded by employing a double-reference beam, double-exposure holographic technique. Optical pathlength data were extracted from the recorded interferometric data and finally three dimensional temperature field inside the cube was reconstructed.

• ETRI Journal
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• v.41 no.1
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• pp.61-72
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• 2019

In this paper, we demonstrate the current concepts in holographic tomography (HT) realized within limited angular range with illumination scanning. The presented solutions are based on the work performed at Warsaw University of Technology in Poland and put in context with the state of the art in HT. Along with the theoretical framework for HT, the optimum reconstruction process and data visualization are described in detail. The paper is concluded with the description of hardware configuration and the visualization of tomographic reconstruction, which is calculated using a provided processing path.

• Korean Journal of Optics and Photonics
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• v.30 no.6
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• pp.243-248
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• 2019

The respiratory tract is an essential part of the respiratory system involved in the process of respiration. However, if stenosis occurs, it interferes with breathing and can even lead to death. Asthma is a typical example of a reversible cause of airway narrowing, and the number of patients suffering from acute exacerbation is steadily increasing. Therefore, it is important to detect airway narrowing early and prevent the patient's condition from worsening. Optical coherence tomography (OCT), which has high resolution, is suitable for observing the microstructure of tissues. In this study we developed an endoscopic OCT system. We combined a 1300-nm OCT system with a servo motor, which can rotate at a high speed. A catheter was pulled back using a linear stage while imaging with 360° rotation by the motor. The motor was selected considering various requirements, such as torque, rotational speed, and gear ratio of pulleys. An ex vivo rabbit tracheal model was used as a sample, and the sample and catheter were immobilized by acrylic structures. The OCT images provided information about the structures of the mucosa and submucosa. The difference between normal and stenosed parts in the trachea was confirmed by OCT. Furthermore, through a three-dimensional (3-D) reconstruction process, it was possible to identify and diagnose the stenosis in the 3-D image of the airway, as well as the cross-sectional image. This study would be useful not only for diagnosing airway stenosis, but also for realizing 3-D imaging.

• Journal of the Optical Society of Korea
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• v.20 no.5
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• pp.607-613
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• 2016

The pleura is known as an end target organ of exposure to toxic environmental materials such as fine particulate matter and asbestos. Moreover, long-term exposure to hazardous materials can eventually lead to fatal lung disease such as diffuse pleural fibrosis or mesothelioma. Chest computed tomography (CT) and ultrasound are gold standard imaging modalities for detection of advanced pleural disease. However, a diagnostic tool for early detection of pleural reaction has not been developed yet due to difficulties in imaging ultra-fine structure of the pleura. Optical coherence tomography (OCT), which provides cross-sectional images of micro tissue structures at a resolution of 2-10 μm, can image the mesothelium with a thickness of ~100 μm and therefore enables investigation of the early pleural reaction. In this study, we induced the early pleural reaction according to a time sequence after pleurodesis using talc, which has been widely used in the clinical field. The pleural reaction in talc grouped according to the time sequence (1st, 2nd, 4th weeks) showed a significant thickening (average thickness: 45 ± 7.5 μm, 80 ± 10.7 μm, 90 ± 12.5 μm), while the pleural reaction in sham and normal groups showed pleural change from normal to minimal thickening (average thickness: 16 ± 5.5 μm, 17 ± 4.5 μm, 15 ± 6.5 μm, and 12 ± 7.5 μm, 13 ± 2.5 μm, 12 ± 3.5 μm). The measurement of pleural reaction by pathologic examinations was well-matched with the measurement by OCT images. This is the first study for measuring the thickness of pleural reactions using a biophotonic modality such as OCT. Our results showed that OCT can be useful for evaluating the early pleural reaction.

• Proceedings of the Optical Society of Korea Conference
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• 2009.02a
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• pp.355-356
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• 2009

• Proceedings of the Optical Society of Korea Conference
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• 2009.02a
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• pp.169-170
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• 2009

We present a quantification protocol to get the alignment factors of a custom-made spectrometer and the nonlinear fitting function between the measured CCD pixel domain and the wavelength domain to apply the spectral-domain optical coherence tomography using fiber Bragg gratings. We have used 4 different center wavelength gratings with a narrow spectral bandwidth (<0.05 nm) and the same reflectivity (>92 %) to calibrate and align the custom-made spectrometer.

• Proceedings of the Optical Society of Korea Conference
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• 2009.02a
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• pp.353-354
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• 2009

• Proceedings of the Optical Society of Korea Conference
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• 2002.07a
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• pp.86-87
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• 2002

생체의용 Optical Coherence Tomography (OCT)는 살아있는 표피의 내부 미세구조의 고해상도 단면 영상을 얻는 기술이다. OCT는 1-2mm의 깊이의 작은 혈관이나 표피의 내부 구조 영상을 얻을 수 있다. OCT의 광원으로는 800nm대와 1300nm대의 파장을 갖는 Edge-emitting Light-Emitting Diode(ELED)와 Super-Luminescent diode(SLD)를 많이 사용하고 있다. 그러나 기존 광원의 가간섭성 길이가 정밀의료계측 분야의 응용에서 요구하는 해상도에 충분하지 못하다. (중략)

• Proceedings of the Optical Society of Korea Conference
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• 2002.07a
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• pp.246-247
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• 2002

OCT(Optical Coherence Tomography)는 실시간에 생체의 단면을 절개하지 않고도 고해상도의 단층 이미지를 얻을 수 있다는 장점을 지니고 있다. 이러한 면에서 OCT는 현재 사용되고 있는 여러 image modality들의 낮은 분해능을 해결할 수 있는 진보된 대안으로 각광을 받고 있다. 최근 OCT에서 가능한 이미지의 분해능은 수 $\mu$m 정도까지 보고되고 있다. (1) 이러한 OCT의 분해능은 사용하는 광원에 의해서 결정된다. (중략)

• Proceedings of the Optical Society of Korea Conference
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• 2004.07a
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• pp.142-143
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• 2004