• Journal of Sensor Science and Technology
• /
• v.17 no.4
• /
• pp.317-324
• /
• 2008

This paper presents an optical doppler tomography(ODT) system using a speaker as a method to achieve depth measurement in a flowing sample. The use of the speaker provides easy implementation with a low cost. The nonlinear characteristics of the speaker has hindered its adaptation because it produces inconsistent fringe frequencies at different depths. This paper reports an adaptive algorithm to compensate the nonlinear characteristics, and could, resultantly, acquire the Doppler frequency shift caused by the sample. The experiment utilizes a flowing scattering particle solution in a capillary tube at a certain flow rate. The Doppler frequency profile over the lumen was calculated by using spectrogram method. and we obtained the velocity image of the sample.

• Optical Science and Technology
• /
• v.10 no.1
• /
• pp.44-50
• /
• 2006

• Proceedings of the Korean Society of Precision Engineering Conference
• /
• 2012.05a
• /
• pp.859-860
• /
• 2012

• Journal of the Optical Society of Korea
• /
• v.10 no.3
• /
• pp.99-104
• /
• 2006

We introduce a novel contrast mechanism for imaging superparamagnetic iron oxide (SPIO) nanoparticles (average diameter ${\sim}100nm$) using magneto-motive optical Doppler tomography (MM-ODT), which combines an externally applied temporally oscillating high-strength magnetic field with ODT to detect the nanoparticles flowing through a glass capillary tube. A solenoid cone-shaped ferrite core extensively increased the magnetic field strength ($B_{max}=1\;T,\;{\Delta}|B|^2=220T^2/m$) at the tip of the core and also focused the magnetic force on targeted samples. Nanoparticle contrast was demonstrated in a capillary tube filled with the SPIO solution by imaging the Doppler frequency shift which was observed independent of the flow rate and direction. Results suggest that MM-ODT may be a promising technique to enhance SPIO nanoparticle contrast for imaging fluid flow.

• Journal of the Korean Society for Nondestructive Testing
• /
• v.33 no.3
• /
• pp.283-288
• /
• 2013

This paper describes development of a high speed Doppler OFDI system for non-invasive vascular imaging. Doppler OFDI (optical frequency domain imaging) is one of the phase-resolved second generation OCT (optical coherence tomography) techniques for high resolution imaging of moving elements in biological tissues. To achieve a phase-resolved imaging, two temporally separated measurements are required. In a conventional Doppler OCT, a pair of massively oversampled successive A-lines is used to minimize de-correlation noise at the expense of significant imaging speed reduction. To minimize a de-correlation noise between targeted two measurements without suffering from significant imaging speed reduction, several methods have been developed such as an optimized scanning pattern and polarization multiplexed dual beam scanning. This research represent novel imaging technique using frequency multiplexed dual beam illumination to measure exactly same position with aimed time interval. Developed system has been verified using a tissue phantom and mouse vessel imaging.

• Journal of the Optical Society of Korea
• /
• v.16 no.2
• /
• pp.174-180
• /
• 2012

In this study, the feasibility of spectral domain optical Doppler tomography for measuring blood flow characteristics in a micro-tube was demonstrated through several experiments. The use of an SD-ODT system in blood flow measurement can provide high resolution images (5 microns resolution). We prepared three capillary tubes to reveal the effect of different concentrations of hematocrit ratio (HR). One tube serves as the control. The two other tubes contained different concentrations of HR (5%, 25%). Three different capillary tube inlet flow velocities were tested in the present study. The Reynolds number (Re) which is based on the capillary tube inner diameter ranges from Re=6 to 48. We calculated a Doppler shift of the power spectrum of the temporal interference fringes with Kasai autocorrelation function to achieve the velocity profile of the flow. As a result, SD-ODT systems could not detect the cell depletion layer in the present study due to the limitation of spatial resolution. Nevertheless, these systems were proven to be capable of observing the RBCs of blood.

• Journal of Institute of Control, Robotics and Systems
• /
• v.10 no.3
• /
• pp.239-248
• /
• 2004

Optical coherence tomography(OCT) is high resolution imaging system which can see the cross section of microscopic organs in the living tissue. In this paper, we analyze the relation between the light source and the resolution of modulated signal in Michelson interferometer. We construct 1-D OCT signal processing hardware such as amplifiers, filters, and demodulate electronic signals from the photo detector. In order to get 2-D OCT image, the synchronization among optical delay line, sample stage and A/D converter is dealt with. In experiments, we verify analog and digital signal processing blocks which apply to the stacks of glasses. Finally we aquire high resolution 2-D OCT image with respect to the onion tissue. We expect that this result can be applied to the medical instrument through performance improvement.

• Transactions of the Korean Society of Mechanical Engineers B
• /
• v.35 no.7
• /
• pp.685-691
• /
• 2011

The aim of this study is to point out the uniqueness of Doppler optical coherence tomography (DOCT) for use in a probe station for (in vivo) visualization of microscale flow and structure and to maximize the effectiveness of DOCT by overcoming its limitations. Conventional DOCT produces images of only one of the velocity components that is parallel to the incident light. In this study, a multi-angle DOCT to quantify a velocity vector field is proposed; this is an extension from a velocity scalar field to a vector field. Quantifying an instantaneous three-dimensional velocity field in a pulsating flow is another challenge because of its limited frame rate. The in-vivo pulsating blood flow is measured by using an electrocardiogram-gated multi-angle DOCT in a hamster cheek pouch model. It is shown that the aliasing problem caused by a relatively low frame rate is resolved by using this method of measurement.

• Journal of the Korean Society for Precision Engineering
• /
• v.24 no.9
• /
• pp.23-31
• /
• 2007

• Journal of Korean Society of Environmental Engineers
• /
• v.31 no.6
• /
• pp.442-448
• /
• 2009

To evaluate the combustion mechanism of each droplet cluster downstream of the premixed spray flame, the simultaneous time-series measurements were conducted by using optical measurement system consisting of laser tomography, multi-color integrated Cassegrain receiving optics (MICRO) and phase Doppler anemometer (PDA). Furthermore, the group combustion number of droplet cluster was estimated experimentally, and the combustion mechanism of droplet cluster was examined applying the theoretical analysis. The group combustion number, $G_c$, was experimentally estimated about all droplet cluster verified by planar images, and it was classified into the internal group combustion mode and the external group combustion mode according to the theoretical analysis. It is found that there are cases in which the group combustion number estimated experimentally for droplet cluster agree or disagree with the classification by theoretical analysis. The reason of disagreement is considered due to that the group combustion number was only estimated by the geometrical arrangement of droplets in cluster, and that the actual phenomenon is three-dimensional but the measurement system is two-dimensional.