• Title/Summary/Keyword: Optical Coherence Tomography

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K-domain Linearization Using Fiber Bragg Grating Array Based on Fourier Domain Optical Coherence Tomography (광섬유 브라그 격자를 이용한 퓨리어 영역 광 결맞음 단층 촬영에서의 파수영역 선형화)

  • Lee, Byoung-Chang;Eom, Tae-Joong;Jeon, Min-Yong
    • Korean Journal of Optics and Photonics
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    • v.22 no.2
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    • pp.72-76
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    • 2011
  • We demonstrate a k-domain linearization using a fiber Bragg grating (FBG) array for Fourier domain optical coherence tomography based on a wavelength swept laser. The k-domain linearization is carried out with an interpolation method using a FBG array with five FBGs. The measured signal-to-noise ratio from the point spread function after k-domain linearization is 12 dB improved over that of without k-domain linearization at the 1 mm depth of the sample. Clear OCT imaging of the slide glass with k-domain linearization could be obtained.

High-resolution imaging of microneedles in biological tissue with optical coherence tomography (광간섭 단층 영상기술을 이용한 생체 내 microneedle 삽입 구조 영상)

  • Kim, Hun;Heo, Jung;Lee, Kang Ju;Ryu, Su Ho;Ryu, Won Hyoung;Joo, Chulmin
    • Transactions of the Society of Information Storage Systems
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    • v.9 no.1
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    • pp.17-21
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    • 2013
  • Optical coherence tomography (OCT) allows non-invasive, cross-sectional optical imaging of biological tissue with high spatial resolution and acquisition speed. In principle, it is analogous to ultrasound imaging, but uses near-infrared light instead of ultrasound, measuring the time-delay of back-scattered light from within biological tissue. Compared to ultrasound imaging, it exhibits superior spatial resolution (1~10 um) and high sensitivity. Therefore, OCT has been applied to a wide range of applications such as cellular imaging, ophthalmology and cardiology. Here, we describe a novel application of OCT technology in visualizing microneedles embedded in tissue that is developed to deliver drugs into the dermis without the injection mark in the human skin. Detailed three-dimensional structural images of microneedles and biological tissues were obtained. Examining structural modification of microneedles and tissues during insertion process would enable to evaluate performance of various types of microneedles in situ.

Heterogeneous Computation on Mobile Processor for Real-time Signal Processing and Visualization of Optical Coherence Tomography Images

  • Aum, Jaehong;Kim, Ji-hyun;Dong, Sunghee;Jeong, Jichai
    • Current Optics and Photonics
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    • v.2 no.5
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    • pp.453-459
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    • 2018
  • We have developed a high-performance signal-processing and image-rendering heterogeneous computation system for optical coherence tomography (OCT) on mobile processor. In this paper, we reveal it by demonstrating real-time OCT image processing using a Snapdragon 800 mobile processor, with the introduction of a heterogeneous image visualization architecture (HIVA) to accelerate the signal-processing and image-visualization procedures. HIVA has been designed to maximize the computational performances of a mobile processor by using a native language compiler, which targets mobile processor, to directly access mobile-processor computing resources and the open computing language (OpenCL) for heterogeneous computation. The developed mobile image processing platform requires only 25 ms to produce an OCT image from $512{\times}1024$ OCT data. This is 617 times faster than the naïve approach without HIVA, which requires more than 15 s. The developed platform can produce 40 OCT images per second, to facilitate real-time mobile OCT image visualization. We believe this study would facilitate the development of portable diagnostic image visualization with medical imaging modality, which requires computationally expensive procedures, using a mobile processor.

A case of Candida albicans-induced fungal keratitis in a Chihuahua dog - with a focus on optical coherence tomographic features

  • Heejong Cho;Manbok Jeong;Sukjong Yoo
    • Journal of Veterinary Science
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    • v.24 no.2
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    • pp.30.1-30.6
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    • 2023
  • A 4-year-old Chihuahua dog was referred for bilateral corneal ulcers. Slightly raised white fluorescein-positive plaque-like corneal lesions in both eyes appeared as intense hyperreflective areas with posterior shadowing on optical coherence tomography (OCT). Based on corneal cytology and culture, Candida albicans-induced fungal keratitis was diagnosed. Despite treatment, on OCT, endothelial plaques, increased stromal infiltration thickness, vertical shapes of the ulcer edge, and necrotic stromal space were judged to be aggravation of the disease, and surgery was performed. Conjunctival grafting surgery with topical 1% voriconazole effectively resolved fungal keratitis. OCT can provide detailed and objective information related to the disease prognosis.

Broadband Wavelength-swept Raman Laser for Fourier-domain Mode Locked Swept-source OCT

  • Lee, Hyung-Seok;Jung, Eun-Joo;Jeong, Myung-Yung;Kim, Chang-Seok
    • Journal of the Optical Society of Korea
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    • v.13 no.3
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    • pp.316-320
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    • 2009
  • A novel broadband wavelength-swept Raman laser was used to implement Fourier-domain mode locked (FDML) swept-source optical coherence tomography (SS-OCT). Instead of a conventional semiconductor optical amplifier, this study used broadband optical fiber Raman amplification, over 50 nm centered around 1545 nm, using a multi-wavelength optical pumping scheme, which was implemented with the four laser diodes at the center wavelengths of 1425, 1435, 1455 and 1465 nm, respectively, and the maximum operating power of 150 mW each. The operating swept frequency of the laser was determined to 16.7 kHz from the FDML condition of 12 km optical fiber in the ring cavity. The OCT images were obtained using the novel broadband wavelengthswept Raman laser source.

Study on application to the field of dentistry using optical coherence tomography (OCT) (치의학 분야에 대한 광간섭 단층영상기기(optical coherence tomography)의 적용 가능성 고찰)

  • Pyo, Se-Wook;Lim, Young-Joon;Lee, Won-Jin;Lee, Jun-Jae
    • The Journal of Korean Academy of Prosthodontics
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    • v.55 no.1
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    • pp.100-110
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    • 2017
  • Purpose: This paper describes the basic principles and the feasibility of the field of dental diagnosis of optical coherence tomography (OCT) used in diverse field of medical diagnosis. Materials and methods: In this review, the research data of OCT were searched from PubMed, medical journal and related papers. Results: Generally, OCT is noninvasive and is possible to secure an excellent spatial resolution and real-time images of biological microstructure. Conclusion: This review discusses not only the basic principles of operation, types, advantages, disadvantages of OCT but also the future applications of OCT technology and their potential in the field of dental diagnosis.