• 센서학회지
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• 제19권6호
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• pp.403-420
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• 2010

Nano and micro structure-based biosensors are promising tool for label-free detection of biomolecular interactions with great accuracy. This review gives a brief survey on nano and micro platforms to sense a variety of analytes such as DNA, proteins and viruses. Among incredible nano and micro structure for bio-analytical applications, the scope of this paper will be limited to micro and nano resonators and nanowire field-effect transistors. Nanomechanical motion of the resonators transducers biological information to readable signals. They are commonly combined with an optical, capacitive or piezo-resistive detection systems. Binding of target molecule to the modified surface of nanowire modulates the current of the nanowire through electrical field-effect. Both detection methods have advantages of label-free, real-time and high sensitive detection. These structures can be extended to fabricate array-type sensors for multiplexed detection and high-throughput analysis. The biosensors based on these structures will be applied to lab-on-a-chip platforms and point-of-care diagnostics. Basic concepts including detection mechanisms and trends in their fields will be covered in this review.

• 센서학회지
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• 제25권2호
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• pp.131-137
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• 2016

In this study, a multilevel visible light communication (VLC) system based on resistor ladder circuit is designed to transmit medical data. VLC technology is being considered as an alternative wireless communication due to various advantages such as ubiquity, license free operation, low energy consumption, and no radio frequency (RF) radiation characteristics. With VLC even in places where traditional RF communication (e.g., Wi-Fi) is forbidden, significant bio-medical signal including the electrocardiography (ECG) and photoplethysmography (PPG) data can be transmitted. More lives could be saved anywhere by this potential advantage of VLC with a fast emergency response time. A multilevel transmission scheme is adopted to improve the data capacity with keeping simplicity, where data transmission rate can increase by log2m times (m is the number of voltage levels) than that of conventional VLC transmission based on on/off keying. In order to generate multi-amplitudes, resistor ladder circuit, which is a basic principle of digital to analog convertor, is employed, and information is transferred through LED (Light-Emitting Diode) with different voltage level. In the receiver side, multilevel signal is detected by optical receiver including a photo diode. Then, the collected data are analyzed to serve the necessary medical care to the concerned patient.

• 센서학회지
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• 제29권3호
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• pp.172-179
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• 2020

We studied an integrated-optic biosensor configuration that operates at a wavelength of 0.63 ㎛ based on the evanescent-wave and two horizontal mode power coupling of Si₃N₄ rib-optical waveguides formed on a Si/SiO₂/Si₃N₄/SiO₂ multilayer thin films. The sensor consists of a single-mode input waveguide, followed by a two-mode section which acts as the sensing region, and a Y-branch output for separating the two output waveguides. The coupling between the two propagating modes in the sensing region produces a periodically repeated optical power exchanges along the propagation. A light power was steered from one output channel to the other due to the change in the cladding layer (bio-material) refractive index, which affected the effective refractive index (phase-shift) of two modes through evanescent-wave. Waveguide analyses based on the rib optical waveguide dimensions were performed using various numerical computational software. Sensitivity values of 12~23 and 65~165 au/RIU, respectively for the width and length of 4 ㎛, and 3841.46 and 26250 ㎛ of the two-mode region corresponding to the refractive index range 1.36~1.43 and 1.398~1.41, respectively, were obtained.

• 한국광학회지
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• 제19권3호
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• pp.193-198
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• 2008

본 논문에서는 폴리머 광도파로 상부에 $TiO_2$(Titanium dioxide)박막이 증착된 굴절률 센서를 구현하였다. 제작된 센서를 이용하여 글리세롤의 굴절률 변화에 따른 출력광의 편광 간섭 변화를 측정하였다. 또한 박막 두께에 따른 편광 간섭의 민감도 변화를 확인하고, 수치해석 결과와 비교하였다. 특히 $TiO_2$가 20 nm 증착된 광도파로에서 $2{\pi}$의 위상차를 갖는 굴절률 변화는 $1.8{\times}10^{-3}$이다.

• 한국광학회지
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• 제22권1호
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• pp.46-52
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• 2011

본 연구에서는 레버 증폭 구조를 이용한 플렉서 기반의 나노 스테이지를 설계, 제작하였다. 제작된 나노 스테이지를 샘플 스테이지로 채용한 공초점현미경을 개발하였다. 2차원 이미징의 구현을 위해서, 기존의 공초점현미경은 레이저를 이미징 평면상에 스캐닝하는 방식으로 구현된다. 본 연구에서는 백 나노미터의 구동정밀도를 가지는 나노 스테이지 위에 놓인 샘플을 2차원으로 스캐닝하면서 2차원 이미지를 구현할 수 있는 공초점현미경을 개발하였다. 플렉서 기반의 나노 스테이지는 이중 판스프링, 변위증폭 레버, PZT 엑추에이터 그리고 변위 센서로 구성 되어 있다. 스테이지의 구동 성능 해석을 위해 상용 유한요소 해석 프로그램을 이용하였다. 현미경에 사용되는 광원은 적색광 레이저이며, 레이저는 여러 광학요소를 거쳐 샘플스테이지의 샘플에 입사되고, 반사된 빛은 광센서인 PMT(Photo Multiplying Tube)로 계측되게 된다. 계측된 빛의 크기를 이용하여서 2차원 이미징을 구현하였다. 개발된 공초점 현미경으로 생쥐 귀의 피부조직을 관찰하여 현미경의 이미징 성능을 검증하였다. 설계된 샘플 스테이지는 기존의 공초점 현미경의 기계적인 Beam 스캐너를 대신함으로써 현미경의 광경로 및 전체시스템을 간소화 하였다.

• 공업화학
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• 제29권6호
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• pp.645-651
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• 2018

한국인의 암 사망률 1위를 차지하는 폐암은 발견되기 전까지 별다른 증상이 없어 환자는 병을 쉽게 인지하지 못하고, 기존의 진단법 또한 초기단계에는 적용이 어렵다. 해결책으로서, 분자수준에서의 체액분석을 폐암진단에 도입하는 방안이 제시되고 있다. 이를 위한 분석기기 가운데 대표적으로는 칩 기반 바이오센서가 있으며, 이 센서의 큰 장점으로는 고가의 분석장비나 숙련된 분석인력이 없이도 현장에서의 진단이 가능하다는 점이다. 본 미니총설에서는 폐암 진단에 활용가능한 혈액 내 바이오마커와 바이오칩 센서의 연구현황을 소개하고 이들의 발전가능성에 대해 논의하고자 한다.

• 한국진공학회:학술대회논문집
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• 한국진공학회 2016년도 제50회 동계 정기학술대회 초록집
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• pp.268-268
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• 2016

Chemical sensors have attracted much attention due to their various applications such as agriculture product, cosmetic and pharmaceutical components and clinical control. A conventional chemical and biological sensor is consists of fluorescent dye, optical light sources, and photodetector to quantify the extent of concentration. Such complicated system leads to rising cost and slow response time. Until now, the most contemporary thin film transistors (TFTs) are used in the field of flat panel display technology for switching device. Some papers have reported that an interesting alternative to flat panel display technology is chemical sensor technology. Recent advances in chemical detection study for using TFTs, benefits from overwhelming progress made in organic thin film transistors (OTFTs) electronic, have been studied alternative to current optical detection system. However numerous problems still remain especially the long-term stability and lack of reliability. On the other hand, the utilization of metal oxide transistor technology in chemical sensors is substantially promising owing to many advantages such as outstanding electrical performance, flexible device, and transparency. The top-gate structure transistor indicated long-term atmosphere stability and reliability because insulator layer is deposited on the top of semiconductor layer, as an effective mechanical and chemical protection. We report on the fabrication of InGaZnO TFTs with silver nanowire as the top gate electrode for the aim of chemical materials detection by monitoring change of electrical properties. We demonstrated that the improved sensitivity characteristics are related to the employment of a unique combination of nano materials. The silver nanowire top-gate InGaZnO TFTs used in this study features the following advantages: i) high sensitivity, ii) long-term stability in atmosphere and buffer solution iii) no necessary additional electrode and iv) simple fabrication process by spray.

• 한국진공학회:학술대회논문집
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• 한국진공학회 2016년도 제50회 동계 정기학술대회 초록집
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• pp.422.1-422.1
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• 2016

Graphene quantum dots (GQDs), a new kind of carbon-based photo luminescent nanomaterial from chemically modified graphene oxide (CMGO) or chemically modified graphene (CMG), has attracted extensive research attention in the last few years due to its outstanding chemical, optical and electrical properties. To further extended its potential applications as optoelectronic devices, solar cells, bio and bio-sensors and so on, intensive research efforts have been devoted to the CMG. However, the CMG, a suspension of aqueous, have problematic since they are prone to agglomeration after drying a solvent. In this study, we synthesized the GQDs from graphite and deposited on silicon substrate by kinetic spray. The photo luminescent properties of deposited GQD films were analyzed and compared with initial GQDs suspension. In addition, its carbon properties were investigated with GQDs solution properties. The properties of deposited GQD films by kinetic spray were similar to that of the GQDs suspension in water. We could provide a pathway for silicon-based silicon based device applications. Finally, the well-adjusted GQD films with photo luminescence effects will show Energy-Down-Shift layer effects on silicon solar cells. The GQD layers deposited at nozzle scan speeds of 40, 30, 20, and 10 mm/s were evaluated after they were used to fabricate crystalline-silicon solar cells; the results indicate that GQDs play an important role in increasing the optical absorptivity of the cells. The short-circuit current density (Jsc) was enhanced by about 2.94 % (0.9 mA/cm2) at 30 mm/s. Compared to a reference device without a GQD energy-down-shift layer, the PCE of p-type silicon solar cells was improved by 2.7% (0.4 percentage points).

• 한국신재생에너지학회:학술대회논문집
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• 한국신재생에너지학회 2009년도 추계학술대회 논문집
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• pp.394-394
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• 2009

Water solubility of conjugated polymers may offer many applications. Potential applications of water-soluble conjugated polymers include the polymer light-emitting diode and new materials for nano and micro hollow-capsules, and bio- or chemo-sensors. We synthesized neutral polyfluorenes containing bromo-alkyl groups by the palladium catalyzed Suzuki coupling reaction. Bromo-alkyl side groups in neutral polyfluorenes were quaternized by tri-methyl amine solution. The electrochemical and optical properties of water-soluble conjugated polymers are discussed. This novel synthesized water-soluble conjugated polymers were used as a interfacial dipole layer between active layer and metal cathode in polymer solar cell for enhancement of open-circuit voltage (Voc), which is one of the most critical factors in determining device characteristics. We also investigated the device performance of polymer solar cell with different metal cathode such as Al, Ag, Au and Cu. In polymer solar cell, novel cationic water-soluble conjugated polymers were inserted between active layer and high-work function cathode (Al, Ag, Au and Cu).

• 한국광학회지
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• 제19권1호
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• pp.73-79
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• 2008

금속선 도파로 면과 금속 평면이 수직으로 적층된 장거리 표면-플라즈몬 도파로 구조를 제안하였으며, 표면-플라즈몬 모드의 특성을 유전체의 굴절율과 두께 변화에 대하여 이론적으로 분석하고 실험적으로 검증하였다. 위층의 금속선 도파로를 S-곡선과 Y-분기 형태로 변형시킨 이중-금속 도파로를 제작하여, 제안된 이중-금속 도파로 구조의 광 소자 응용 가능성을 살펴보았다. 제안된 이중금속 구조에서는 도파로 코어에 해당하는 두 금속 박막 사이의 유전체 굴절률을 임의로 선택하여도 장거리 표면 플라즈몬 모드가 존재할 수 있으며, 표면-플라즈몬 모드의 전파거리는 두 금속 박막 사이의 유전체 두께를 조절함으로써 증가시킬 수 있다. 또한, 이중-금속 도파로는 표면-플라즈몬을 전달할 뿐만 아니라, 삽입된 코어 유전체에 전압 및 전류를 인가하기에도 매우 적합한 구조로서, 표면-플라즈몬 능동소자 및 비선형 소자 구현에 많은 가능성을 열어줄 것으로 기대된다.