• Title/Summary/Keyword: Opthalmic

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The Study on the Improvement of Function and Sensation Symptoms of Binocular Vision for Vision Training Methods (시기능 훈련방법에 의한 양안시 기능적.감각적 증상 개선 효과 연구)

  • Lee, Chang-Seon;Kim, Ki-Hong
    • Journal of Korean Ophthalmic Optics Society
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    • v.15 no.2
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    • pp.185-193
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    • 2010
  • Purpose: The purpose of this study was to investigated the effect of vision training methods on the visual function and sensation symptoms of patients with convergence insufficiency. Mehtods: The vision training observation group included 35 clients who had binocular vision disorders without opthalmic diseases or vertical phoria. They took the each vision training once a week for eight weeks and were investigated for the function and sensation symptoms changes of binocular vision. Results: According to the results, all vision training methods showed improvement of binocular vision function and sensation symptoms. For Worth 4 Dot test, Titmus test and red lenses observed the changes in fusion rate, all the training methods showed similar improvements. Conclusions: The study proved that vision training methods for patients with binocular vision was effective for the improvement of the phoria, function and sensation symptoms of these patients.

Preparation of Magnetic Chitosan Microsphere Particles (나노 크기의 마그네타이트 입자를 이용한 자성 키토산 미소구체의 제조)

  • Ko, Sang-Gil;Cho, Jun-Hee;Ahn, Yang-Kyu;Song, Ki-Chang;Choi, Eun-Jung
    • Journal of the Korean Magnetics Society
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    • v.16 no.1
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    • pp.66-70
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    • 2006
  • Magnetite nanoparticles, which have been extensively used in many fields, were encapsulated with a natural polymer, chitosan, to improve their biocompatibility. We have synthesized magnetite $(Fe_3C_4)$ nanoparticles using chemical coprecipitation technique with sodium oleate as surfactant. Nanoparticle size can be varied from 1.2 to 7.4nm by controlling the sodium oleate concentration. Magnetite phase nanoparticles could be observed from X-ray diffraction. Magnetic colloid suspensions containing particles with sodium oleate and chitosan have been prepared. High magnetic property chitosan-microsphere particles were prepared from oleate-coated magnetite suspension using spray method. The surftce, and tile morphology of the magnetic chitosan microsphere particles were characterized using optical microscope and scanning electron microscope. Magnetic hysteresis measurement were performed using a superconducting quantum interference device (SQUID) magnetometer at room temperature to investigate the magnetic properties of the chitosan microspheres including magnetite nanoparticles. The SQUID measurements revealed superparamagnetism of nanoparticles.

Preparation of Magnetite Nanoparticles Encapsulated with Biodegradable Polymer (PLGA) (생분해성 고분자(PLGA)로 캡슐화한 Magnetite 나노입자의 제조)

  • Lee, Ho-Seok;Choung, Il-Yeop;Song, Ki-Chang;Ahn, Yang-Kyu;Choi, Eun-Chung
    • Journal of the Korean Magnetics Society
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    • v.16 no.1
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    • pp.107-110
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    • 2006
  • Magnetite nanoparticles encapsulated with biodegradable polymer [poly(D,L-lactide-co-glycoiide), PLGA] were prepared by an emulsification-diffusion method. To investigate the effect of type of organic solvents on the mean particle sizes of obtained composite particles, different organic solvents [ethyl acetate (EA), propylene carbonate (PC) and acetone (ACE)] were used with a stabilizer [didodecyl dimethyl ammonium bromide (DMAB)]. The particle size of nanoparticles was observed by the dynamic light scattering method. When EA and PC as partially water-soluble solvents were used, small composite nanoparticles below 80nm were obtained, while large composite nanoparticles above 330nm were prepared for ACE as a fully water-soluble solvent.

Synthesis of Monodisperse Magnetite Nanocrystallites Using Sonochemical Method (음향화학법을 이용한 균일한 나노 자성체의 합성)

  • Cho, Jun-Hee;Ko, Sang-Gil;Ahn, Yang-Kyu;Song, Ki-Chang;Choi, Eun-Jung
    • Journal of the Korean Magnetics Society
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    • v.16 no.3
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    • pp.163-167
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    • 2006
  • Ultrasonic irradiation in a solution during the chemical reaction may accelerate the rate of the reaction and the crystallization at low temperature. We have synthesized nanometer sized magnetite particles using coprecipitation method, sonochemical method without surfactant, and sonochemical method with surfactant, in order to investigate the effect of ultrasonic irradiation and surfactant on the coprecipitates of metal ions. The size of the magnetite nanoparticles prepared by coprecipitation method, and sonochemical method without surfactant showed broad distributions. But we got uniform nanoparticles using a sonochemical method with oleic acid. The average size of the particles can be controlled by the ratio $R=[H_2O]/[surfactant]$. The size of the magnetite nanoparticles prepared by this method showed narrow distributions. We have characterized the nanoparticles using an X-ray diffraction (XRD), a superconducting quantum interference device (SQUID), and atomic force microscope (AFM). The size and distribution of the magnetite nanoparticles were measured by dynamic light scattering (DLS) method.

A Study of Ultrastructure on attachment of Soft Contact Lens Surface of Incubated Pseudomonas aeruginosa (배양된 Pseudomonas aeruginosa의 소프트 콘택트 렌즈 표면부착에 대한 미세구조적 연구)

  • Kim, Douk Hoon;Park, Yong Tae;You, Hae Byung
    • Journal of Korean Ophthalmic Optics Society
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    • v.5 no.2
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    • pp.11-14
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    • 2000
  • The soft contact lens was very simple technique in handling, good sensation in fitting, good effect of a beauty, and good attachment state on the cornea in physical movement. So that, the subjects have used the correct of visual acuity. If the contact lens handling have not skill, they have acquired the side effect on eye. To analysis of a study of ultrastructure on soft contact lens surface of incubated P. aeruginosa. We have observed the soft contact lens surface by SEM. We have founded the good technical method. On the method of sample process of manufacture, the best observation of samlpe tissue was $OsO_4$ postfixation and tannic acid treatment. In this case, P. aeruginosa was a rod shape and one cilia in ultrastructure and the identification was very good. But, On the process of manufacture have not used the $OsO_4$ and tannic acid treatment, this tissue sample appeared the foreign body materials and artifacts, and the identification of the P. aeruginosa was very difficult.

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Ocular transport of hydrophilic drugs: Enhancement of the paracellular penetration across cornea and conjunctiva in the rabbit (수용성약물의 안점막 투과기전에 관한 연구: 토끼의 각막 및 결막 세포간극경로의 투과촉진)

  • Chung, Youn-Bok;Lyoo, Seen-Suk;Han, Kun
    • Journal of Pharmaceutical Investigation
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    • v.26 no.1
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    • pp.43-53
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    • 1996
  • The objective of this study was to determine whether 4-phenylazobezyloxycarbonyl-Pro-Leu-Gly-Pro-D-Arg (Pz-peptide), an enhancer of hydrophilic solute permeability in the intestine, could elevate the paracellular permeability of hydrophilic drugs across cornea and conjunctiva in the rabbit. The in-vitro penetration of hydrophilic drugs (mannitol, atenolol) and lipophilic drug (propranolol) across the rabbit cornea and conjunctiva was studied either in the presence or absence of 3 mM Pz-peptide. Drug penetration was evaluated using the modified Ussing chamber. The conjunctiva was more permeable than the cornea to all drugs. Pz-peptide showed enhanced effects on the drug transport across cornea and conjunctiva in a concentration dependent manner. Effects or ion transport inhibitor on the mannitol penetration were then investigated. Mannitol penetration was not changed by serosal addition of $100\;{\mu}M$ ouabain, suggesting that $Na^+/K^+$ ion tranporter was not involved in the Pz-peptide induced elevation of paracellular drug permeability. Furthermore, effects of Pz-peptide and EDTA on the transport of atenolol and propranolol into the ocular tissues or blood circulation after its administration into both eyes were investigated. EDTA showed enhanced effect on propranolol transport into the ocular tissues, but Pz-peptide did not show significant difference. Systemic absorption of propranolol by the addition of EDTA or Pz-peptide was not changed. On the other hand, EDTA and Pz-peptide elavated the atenolol transport into the ocular tissues. The transport of atenolol into the blood circulation was also enhanced by the addition of EDTA, but no effect was observed by the addition of Pz-peptide. The above findings suggest that Pz-peptide would be used as an paracellular pathway enahncer of hydrophilic drugs into the eye, without affecting the systemic absortion of topically applied opthalmic drugs.

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The Study on the Effect of Vision Training System (시기능 훈련 시스템을 이용한 훈련 효과에 관한 연구)

  • Lee, Chang-Seon;Son, Jeong-Sik;Kim, In-Su;Kang, Sung Soo;Lee, Dong-Hee;Kim, Ki-Hong
    • Journal of Korean Ophthalmic Optics Society
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    • v.14 no.1
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    • pp.81-86
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    • 2009
  • Purpose: We developed the MYSTERY CIRCLE vision training program which was suitable for Korean people. We compared it with the established programs, Block string and Anaglyphs in aspect of functional, sensory, and symptomatical changes of binocular vision. Mehtods: The vision training observation group included 75 clients (male=40, female=35) who had binocular vision disorders without opthalmic diseases or vertical phoria. Results: According to the results, all training methods showed improvement of binocular vision function, sensation and symptoms. But the Block String had low participation, reference rate of subjects and success rate and showed the different degree of improvement depending on individuals. Anaglyphs method showed high participation and improvement. But it had a low degree of success rate and preference rate. Conclusions: MYSTERY CIRCLE method showed the highest participation, reference rate of subjects, success rate, and high degree of improvement. Therefore we suggest that MYSTERY CIRCLE is an effective and alternative method for binocular vision disorder therapy.

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The study to develope of optical glass(LaF, KzFS1, LBO) (광학유리(LaF, KzFS1, LBO) 개발에 관한 연구)

  • Cha, Jung Won;Park, Moon Chan
    • Journal of Korean Ophthalmic Optics Society
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    • v.5 no.1
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    • pp.19-30
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    • 2000
  • LaF, KzFS1, LBO glass were manufactured successfully by using platinum crucible in LaF and using clay crucible in the KzFS1 and LBO. There was optically transparent and the refractive indexes were measured by minum deviation method of prism. LaF, KzFS1, LBO show that the refrective indexes are $n_d$ = 1.770 in LaF, $n_d$ = 1.603 in KzFS1, $n_d$ = 1.560 in LBO. The transmittance were obtained that LaF has 85%, and KzFS1 has 83% and LBO has 89% in visible range. These glasses have no any absorption spectrum under visible range. Therefore it has no any color.

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Optician Training System at a Professional School Education and Improvement Plan of Curriculum in the Department of Optical Science (전문대학 안경사 양성제도 및 안경광학과 교육과정 개선방안)

  • Song, Yang Joo
    • Journal of Korean Ophthalmic Optics Society
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    • v.2 no.1
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    • pp.111-126
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    • 1997
  • I concluded as follows after analyzing the problem of the curriculum in the Department of Optical Science at a college of professional education for the purpose of training desireable opticians. The years required for competing a course of study at the Department of Optical Science at a college of professonal education have to be extended from the present two school years to three years for the short run and have to be extended to four years for the long run. The distribution ratio of subjects in the slate examination should be readjusted and the field of contect lens. Also the system of the slate examination should strengthen by adding practical processing test with the present selective written examination. The Curriculum of department of Optical Science curriculum at a college of professional education should be reorganized reinforce experiment and practice, namely, the subject for experiment and practice, such as Making of specific glasses and Test method of phorpter etc, should be reinforced. The knowledge for goods should be included in clinical training and it is reasonable to constitute the theory vs the practice in the ratio of five to five. The number of the Department of Optical Science should be increased two or more for per forty students and it is desirabled that only the professors who major optical Science or opthalmic medical science, or have Optician Licence should give lecture. The experiment a practice should be enlarged and it is necessary to secure or to adopt practice hours, practice site, machinery and parts, practice assistant and etc. It is reasonable that clinical training include the knowledge of goods, business practice and etc. and that a practice examiner has the qualification as an optician who has education background higher that the college of professional education.

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Crystallographical Characteristics of Solar Salts Produced from Jeonnam Area by X-Ray Diffraction Technique (X선 회절법에 의한 전남지역 천일염의 결정학적 특성)

  • Jeong, Byung-Jo;Kim, Yong;Kim, Chang-Dae;Hyun, Seung-Cheol;Ham, Gyung-Sik
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.38 no.9
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    • pp.1284-1288
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    • 2009
  • Identification of various inorganic compound crystals contained in solar salts, which are produced from 12 areas of Jeonnam, was firstly made by the X-ray diffraction (XRD) technique. The analysis of the XRD spectra was carried out on the basis of Joint Committee on Powder Diffraction Standards (JCPDS) data and the results of Energy Dispersive X-ray Spectrometer (EDX) measurements. In particular, the analysis of the XRD spectra supported that each solar salt contains $Na_2S$ (Shinan Jeungdo and Sinui), $KMgCl_3$ (Shinan Bigeum), $Ca(ClO_3)_2$ (Shinan Docho), $CaAl_4O_7$ (Haenam Songji), $CaSiO_3$ and $CaCl_2$ (Goheung) as inorganic compound crystals, which have not been reported for the solar salts. Also, the XRD results indicated that the solar salts maintain a cubic NaCl crystal structure without any change of lattice parameters etc. However, it was shown in the Field Emission Scanning Electron Microscope (FE-SEM) images that an external form of the solar salts has a lamination layer shape of a cubic structure, which is different from a simple cubic form for the purified salts and the reagent NaCl.