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A Case Report of Lumbar Spine Failed Back Surgery Syndrome (FBSS) Patient Treated with Korean Medicine: Long-Term Progress Including Postpartum Aggravation (보존적 한방치료를 시행한 척추 수술 실패 증후군 환자 증례보고 : 출산 후 악화를 포함한 장기 경과 관찰)

  • Roh, Ji-ae;Lee, Ji-won;Byun, Da-young;Hong, Jung-soo;Kim, Dong-jin
    • The Journal of Internal Korean Medicine
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    • v.40 no.1
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    • pp.126-135
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    • 2019
  • Background: Because of fear of reoperation and low efficiency, some patients with failed back surgery syndrome (FBSS) opt for Korean medicine treatment. Gold standard treatment is not present for FBSS, therefore both surgical and non-surgical treatment are possible. Studies of Korean conservative medicine for FBSS had a short duration of treatment and mainly pre- and post-treatment comparisons. And case of female patients who have worsened after childbirth is rare. The purpose of this study was to report long-term follow-up and rare cases of FBSS. Case summary: A 33-year-old female patient diagnosed with lumbar disc herniation complained with low back pain and radicular pain in the left leg after surgery in 2011. Acupuncture and decoction (Cheongpa-jeon, GCSB-5) were administered to her twice a day for about 6 years and 6 months. The patient's complaints improved with each hospitalization, and Magnetic Resonance Imaging (MRI) showed a slight decrease in the size of the recurrent disc (L4/5) and a newly developed disc (L5/S1) that had deteriorated after delivery. Conclusion: Korean medicine could be used to manage the pain of lumbar spine FBSS patients for 6-7 years and to alleviate lumbago after delivery.

Effects of Flexi-bar Exercise on Shoulder Pain, Disfunction, Quality of Life and Range of Motion in Women with Breast Cancer Surgery (유방암 수술을 한 여성에게 Flexi-bar 운동이 견관절 통증, 기능장애, 삶의 질, 관절가동범위에 미치는 영향)

  • Lee, Min-ji;Kwon, O-kook;Kim, Youn-jin;Shin, Eui-joo;Yu, Dal-young
    • The Journal of Korean Academy of Orthopedic Manual Physical Therapy
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    • v.27 no.2
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    • pp.45-54
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    • 2021
  • Background: The purpose of this study was to investigate the effects of flexi-bar exercise on shoulder pain, dysfunction, quality of life, and range of motion of women with breast cancer surgery. Methods: A total of 42 female patients who had breast cancer were included in this study. By drawing lots, subjects were divided into a flexi-bar exercise group (FBG, n=21) and a general breast cancer group (GBG, n=18). The effects of flexi-bar exercise on patients were evaluated in terms of the visual analogue scale (VAS), the shoulder pain and disability index (SPADI), the European organization for the research and treatment of cancer quality of life questionnaire (EORTC QLQ-C30), the breast cancer specific EORTC quality of life questionnaire (EORTC QLQ-BR23), and range of motion (ROM), all of which were measured pre- and post- intervention followed by evaluation. Results: A significant increase was pain, functional disability level, quality of life, ROM within the two groups (p<.01). There were pain, functional disability level, quality of life, ROM post test then invention were significant between the two groups(p<.01). Conclusion: The flexi-bar exercise has a positive treatment effect on breast cancer patients.

ω-6 and ω-3 Polyunsaturated Fatty Acids: Inflammation, Obesity and Foods of Animal Resources

  • Hwa Yeong Jeong;Yang Soo Moon;Kwang Keun Cho
    • Food Science of Animal Resources
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    • v.44 no.5
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    • pp.988-1010
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    • 2024
  • Obesity, as defined by the World Health Organization (WHO), is excessive fat accumulation that can pose health risks and is a disorder of the energy homeostasis system. In typical westernized diets, ω-6 polyunsaturated fatty acids (PUFAs) vastly exceed the amount of ω-3 PUFAs, with ω-6/ω-3 ratios ranging from 10:1 to 25:1. ω-6 PUFAs, such as arachidonic acid, have pro-inflammatory effects and increase obesity. On the other hand, ω-3 PUFAs, including eicosapentaenoic acid and docosahexaenoic acid, have anti-inflammatory and anti-obesity effects. Linoleic acid (LA) and alpha-linolenic acid (ALA) are synthesized in almost all higher plants, algae, and some fungi. However, in humans and animals, they are essential fatty acids and must be consumed through diet or supplementation. Therefore, balancing LA/ALA ratios is essential for obesity prevention and human health. Monogastric animals such as pigs and chickens can produce meat and eggs fortified with ω-3 PUFAs by controlling dietary fatty acid (FA). Additionally, ruminant animals such as feeder cattle and lactating dairy cows can opt for feed supplementation with ω-3 PUFAs sources and rumen-protected microencapsulated FAs or pasture finishing. This method can produce ω-3 PUFAs and conjugated linoleic acid (CLA) fortified meat, milk, and cheese. A high ω-6/ω-3 ratio is associated with proinflammation and obesity, whereas a balanced ratio reduces inflammation and obesity. Additionally, probiotics containing lactic acid bacteria are necessary, which reduces inflammation and obesity by converting ω-6 PUFAs into functional metabolites such as 10-hydroxy-cis-12-octadecenoic acid and CLA.

A Novel Draft Genome-Scale Reconstruction Model of Isochrysis sp: Exploring Metabolic Pathways for Sustainable Aquaculture Innovations

  • Abhishek Sengupta;Tushar Gupta;Aman Chakraborty;Sudeepti Kulshrestha;Ritu Redhu;Raya Bhattacharjya;Archana Tiwari;Priyanka Narad
    • Microbiology and Biotechnology Letters
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    • v.52 no.2
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    • pp.141-151
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    • 2024
  • Isochrysis sp. is a sea microalga that has become a species of interest because of the extreme lipid content and rapid growth rate of this organism indicating its potential for efficient biofuel production. Using genome sequencing/genome-scale modeling for the prediction of Isochrysis sp. metabolic utilities there is high scope for the identification of essential pathways for the extraction of byproducts of interest at a higher rate. In our work, we design and present iIsochr964, a genome-scale metabolic model of Isochrysis sp. including 4315 reactions, 934 genes, and 1879 metabolites, which are distributed among fourteen compartments. For model validation, experimental culture, and isolation of Isochrysis sp. were performed and biomass values were used for validation of the genome-scale model. OptFlux was instrumental in uncovering several novel metabolites that influence the organism's metabolism by increasing the flux of interacting metabolites, such as Malonyl-CoA, EPA, Protein and others. iIsochr964 provides a compelling resource of metabolic understanding to revolutionize its industrial applications, thereby fostering sustainable development and allowing estimations and simulations of the organism metabolism under varying physiological, chemical, and genetic conditions. It is also useful in principle to provide a systemic view of Isochrysis sp. metabolism, efficiently guiding research and granting context to omics data.

An Investigation on the Flow Characteristics of Water Spray Nozzle (미세 물분무 노즐의 유동특성에 관한 연구)

  • Jun, You Woo;Han, Young Tak;Kim, Chang Seob;Kim, Chang;Ryou, Hong-Sun
    • Fire Science and Engineering
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    • v.29 no.5
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    • pp.29-33
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    • 2015
  • In this study, the relations of flow rate, discharging distance and droplet size are measured in accordance with the nozzle shape. The dual type nozzles of LPN142 and LPN148, which have identical core diameter (6.0 mm) and the different radial injection angles (${\theta}_2=142^{\circ}$ and $148^{\circ}$), are manufactured. The distribution diameters with discharging distance are quantified by UL2167 test standard. The relations between discharging angle and droplet sizes, which are measured by the method of Helium-Neon laser equipment, are obtained by the empirical correlation as working pressure increase. Moreover, the extinction coefficient, which is major parameter of the radiative transport equation (RTE) is analyzed with variable droplet sizes. Thus, it is possible to opt the nozzle's shape by analyzing the relations of working pressure, spray distance, droplet size and fire characteristics at minimum allowable flow rate.

Stock assessment of elkhorn sculpin (Alcichthys alcicornis) along the Uljin area in the East Sea of Korea

  • Lee, Soo-Jeong;Zhang, Chang-Ik;Choi, Young-Min;Lee, Dong-Woo;Lee, Jae-Bong
    • Journal of the Korean Society of Fisheries and Ocean Technology
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    • v.49 no.4
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    • pp.432-439
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    • 2013
  • This study was performed to assess the current stock condition of elkhorn sculpin along the Uljin area in the East Sea of Korea. To assess the state of the stock, yield-per-recruit (YPR) and spawning biomass-perrecruit (SBPR) analyses were performed. Estimates of $F_{max}$ and $F_{0.1}$ were 2.10/year and 0.48/year, respectively, and those of $F_{35%}$ and $F_{40%}$ were 0.66/year and 0.54/year, respectively. Current fishing mortality was estimated at 0.63/year and the current age at first capture was 2.41years. $F_{40%}$ was set as the target reference point of the stock. SBPR at $F_{40%}$ and current SBPR were estimated to be 41.85g and 37.77g, respectively. Estimated FOTY which is the fishing mortality for the overfished threshold yield was 0.49/year. The ratio of SBPR/$SBPR_{MSY}$ was calculated as 0.90 and that of $F/F_{OTY}$ was 1.05. The ratio of $t_c/t_{c\;opt}$ was calculated as 1.15 and that of $F/F_{OTY}$ was 1.17. Therefore, the current stock condition of elkhorn sculpin along the Uljin area of Korea has not been overfished, however, it indicates that a light overfishing is going on this stock.

Design of Ka-band Feed Horn and Cassegrain Antenna (Ka-band 대역의 급전 혼과 카셋그레인 안테나 개발)

  • Ahn, Seung-Beom;Choo, Ho-Sung;Kang, Jin-Seob
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.18 no.8
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    • pp.943-953
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    • 2007
  • In this paper, we propose a Cassegrain antenna with a scalar feed horn opt rating in Ka-band. For an effective EM simulation of the Cassegrain antenna, the near-field of the feed hone is used ai the equivalent source of the Cassegrain antenna using the surface equivalent theorem. A corrugated circular horn operating with $HE_{11}$ mode is used as the feed horn. The angle and feed center of the main and sub reflectors are optimized to achieve maximum antenna efficiency. The designed feed horn shows the gain of 19dBi, the side-lobe level of less than -25dB and the half power beam width of $20^{\circ}$ at 33 GHz. The Cassegrain antenna shows the gain of 41dBi, the efficiency of 60%, the side-lobe level of less than -20dB and the half power beam width of $1.2^{\circ}$.

M2M Transformation Rules for Automatic Test Case Generation from Sequence Diagram (시퀀스 다이어그램으로부터 테스트 케이스 자동 생성을 위한 M2M(Model-to-Model) 변환 규칙)

  • Kim, Jin-a;Kim, Su Ji;Seo, Yongjin;Cheon, Eunyoung;Kim, Hyeon Soo
    • KIISE Transactions on Computing Practices
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    • v.22 no.1
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    • pp.32-37
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    • 2016
  • In model-based testing using sequence diagrams, test cases are automatically derived from the sequence diagrams. For the generation of test cases, scenarios need to be found for representing as a sequence diagram, and to extract test paths satisfying the test coverage. However, it is hard to automatically extract test paths from the sequence diagram because a sequence diagram represents loop, opt, and alt information using CombinedFragments. To resolve this problem, we propose a transformation process that transforms a sequence diagram into an activity diagram which represents scenarios as a type of control flows. In addition, we generate test cases from the activity diagram by applying a test coverage concept. Finally, we present a case study for test cases generation from a sequence diagram.

Thoracodorsal artery flaps for breast reconstruction-the variants and its approach

  • Thomsen, Jorn Bo;Rindom, Mikkel Borsen;Rancati, Alberto;Angrigiani, Claudio
    • Archives of Plastic Surgery
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    • v.48 no.1
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    • pp.15-25
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    • 2021
  • Thoracodorsal artery (TDA) flaps, ranging from the vascular-pedicled thoracodorsal artery perforator (TDAP) flap, the propeller TDAP flap, and the muscle-sparing latissimus dorsi (MSLD) flap to the conventional latissimus dorsi (LD) flap and the extended LD flap, can all be used for breast reconstruction. The aim of this paper and review is to share our experiences and recommendations for procedure selection when applying TDA-based flaps for breast reconstruction. We describe the different surgical techniques and our thoughts and experience regarding indications and selection between these procedures for individual patients who opt for breast reconstruction. We have performed 574 TDA flaps in 491 patients: 60 extended LD flaps, 122 conventional LD flaps, two MSLD flaps, 233 propeller TDAP flaps, 122 TDAP flaps, and 35 free contralateral TDAP flaps for stacked TDAP breast reconstruction. All the TDA flaps are important flaps for reconstruction of the breast. The LD flap is still an option, although we prefer flaps without muscle when possible. The vascular-pedicled TDAP flap is an option for experienced surgeons, and the propeller TDAP flap can be used in most reconstructive cases of the breast, although a secondary procedure is often necessary for correction of the pedicle bulk. The extended LD flap is an option for women with a substantial body mass index, although it is associated with the highest morbidity of all the TDA flaps. The MSLD flap can be used if the perforators are small or if dissection of the perforators is assessed to be hazardous.

Optimizing the Life Cycle Cost of a Solar Water Heating System in an Office Building Through Simulation (사무소건물 태양열급탕시스템의 LCC 최적화 시뮬레이션)

  • Ko, Myeong-Jin;Choi, Doo-Sung;Chang, Jae-D.;Kim, Yong-Shik
    • Korean Journal of Air-Conditioning and Refrigeration Engineering
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    • v.22 no.12
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    • pp.859-866
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    • 2010
  • This study examined the economics of a solar water heating system for an office building using life cycle cost (LCC) optimization simulations. The numerical simulations were conducted with TRNSYS and GenOpt employing the Hooke-Jeeves algorithm. The solar collector area, slope, mass flow rate per collector area and storage tank volume were selected as the main design parameters of the solar water heating system. The LCC optimization simulations of the system were carried out for cases where water temperature was $60^{\circ}C$ and $50^{\circ}C$. The results showed that for water temperature at $60^{\circ}C$ and $50^{\circ}C$ the collector area could be decreased by 17% and 28%, storage tank volume could be decreased by 49% and 54%, and mass flow rate per collector area increased by 5% and 9% respectively compared to a non-optimized system. The LCC of the system was reduced by 4% for $60^{\circ}C$ and 7% for $50^{\circ}C$. The initial installation cost of the system was reduced by 24% for $60^{\circ}C$ and 34% for $50^{\circ}C$. However, the operating cost of the system increased by 16% for $60^{\circ}C$ and 36% for $50^{\circ}C$ compared to a traditional solar water heating system.