• Title/Summary/Keyword: Operating Organization

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Functional annotation of uncharacterized proteins from Fusobacterium nucleatum: identification of virulence factors

  • Kanchan Rauthan;Saranya Joshi;Lokesh Kumar;Divya Goel;Sudhir Kumar
    • Genomics & Informatics
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    • v.21 no.2
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    • pp.21.1-21.14
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    • 2023
  • Fusobacterium nucleatum is a gram-negative bacteria associated with diverse infections like appendicitis and colorectal cancer. It mainly attacks the epithelial cells in the oral cavity and throat of the infected individual. It has a single circular genome of 2.7 Mb. Many proteins in F. nucleatum genome are listed as "Uncharacterized." Annotation of these proteins is crucial for obtaining new facts about the pathogen and deciphering the gene regulation, functions, and pathways along with discovery of novel target proteins. In the light of new genomic information, an armoury of bioinformatic tools were used for predicting the physicochemical parameters, domain and motif search, pattern search, and localization of the uncharacterized proteins. The programs such as receiver operating characteristics determine the efficacy of the databases that have been employed for prediction of different parameters at 83.6%. Functions were successfully assigned to 46 uncharacterized proteins which included enzymes, transporter proteins, membrane proteins, binding proteins, etc. Apart from the function prediction, the proteins were also subjected to string analysis to reveal the interacting partners. The annotated proteins were also put through homology-based structure prediction and modeling using Swiss PDB and Phyre2 servers. Two probable virulent factors were also identified which could be investigated further for potential drug-related studies. The assigning of functions to uncharacterized proteins has shown that some of these proteins are important for cell survival inside the host and can act as effective drug targets.

Accuracy Evaluation of KASS Augmented Navigation by Utilizing Commercial Receivers

  • Sung-Hyun Park;Yong-Hui Park;Jin-Ho Jeong;Jin-Mo Park
    • Journal of Positioning, Navigation, and Timing
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    • v.12 no.4
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    • pp.349-358
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    • 2023
  • The Satellite-Based Augmentation System (SBAS) plays a significant role in the fields of aviation and navigation: it corrects signal errors of the Global Navigation Satellite System (GNSS) and provides integrity information to facilitate precise positioning. These SBAS systems have been adopted as international standards by the International Civil Aviation Organization (ICAO). In recent SBAS system design, the Minimum Operational Performance Standards (MOPS) defined by the Radio Technical Commission for Aeronautics (RTCA) must be followed. In October 2014, South Korea embarked on the development of a Korean GPS precision position correction system, referred to as Korea Augmentation Satellite System (KASS). The goal is to achieve APV-1 Standard of Service Level (SoL) service level and acquisition of CAT-1 test operating technology. The first satellite of KASS, KASS Prototype 1, was successfully launched from the Guiana Space Centre in South America on June 23, 2020. In December 2022 and June 2023, the first and second service signals of KASS were broadcasted, and full-scale KASS correction signal broadcasting is scheduled to start at the end of 2023. The aim of this study is to analyze the precision of both the GNSS system and KASS system by comparing them. KASS is also compared with Japan's Multi-functional Satellite Augmentation System (MSAS), which is available in Korea. The final objective of this work is to validate the usefulness of KASS correction navigation in the South Korean operational environment.

An Importance Analysis of Coworking Space Organization and Operating Components (코워킹 스페이스의 구성과 운영요소에 대한 중요도 분석)

  • Bae, Chul Hee;Kim, Jung Youp;Lee, Hyun Seok
    • Korea Real Estate Review
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    • v.28 no.4
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    • pp.23-35
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    • 2018
  • The shared-office business started with the lending of office spaces such as meeting rooms. From this came the coworking space, which maximizes the collaboration among the residents and promotes synergy among them. The purpose of this study was to analyze the characteristics of the coworking space. In addition, this study derived the factors that are considered important among the hardware- and software-level operating components, and presented the priorities according to the importance through a questionnaire survey and analysis for the employees currently utilizing a coworking space. For the results of the analysis, the top elements in the survey were found to be "spatial composition," "membership management," coworking management," and "architectural elements." In addition, when the general items were analyzed according to their characteristics, it was found that there was a difference in priority level among the elements of each characteristic. These results are expected to be useful when designing coworking spaces in the future. The results of this study can be used as the basic data for solving the problems of small companies and the environment, among others. Furthermore, the results of this study can be utilized as the basic data for the development of a collective shared community through linking at the local or national level, rather than being limited to a single space.

A Sustainable Operation Plan for School Gardens - Based on a Survey of Elementary School Gardens in Seoul (학교 텃밭의 지속적인 운영방안에 관한 연구 - 서울특별시 초등학교의 학교 텃밭 실태조사를 바탕으로 -)

  • Choi, I-Jin;Lee, Jae Jung;Cho, Sang Tae;Jang, Yoon Ah;Heo, Joo Nyung
    • Journal of the Korean Institute of Landscape Architecture
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    • v.46 no.4
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    • pp.36-48
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    • 2018
  • This study surveyed 599 elementary schools in Seoul to provide measures for the quantitative expansion and sustainable operation of environmentally-friendly school garden. Of all schools, 161 schools had formed and were operating school gardens. The total area of school gardens was $166,901m^2$ and the mean area was $131.2m^2$ in elementary, junior high and high schools in Seoul. Meanwhile, the total area of school gardens was $65,493m^2$ and the mean area was $363m^2$ in 161 schools that participated in the survey, indicating $1.15m^2$ per student. Of these schools, 11.8% were operating gardens themselves, while 50.3% were operating gardens that had been newly renovated or environmentally improved by institutional support projects after initially managing gardens themselves. According to the locations of school gardens, mixed-type gardening (a combination of school gardening and container vegetable gardening) accounted for 34.8%, followed by school gardening at 32.9%, container vegetable gardening at 29.2%, and suburb community gardening at 3.1%. Those in charge of garden operations were teachers at 51.6%, comprising the largest percentage. Facilities built when forming the garden included storage facilities for small-scale greenhouses and farming equipment at 26.1%, accounting for the largest percentage. No additional facilities constructed accounted for 21.7%. The greatest difficulty in operating gardens was garden management at 34.2%. The most needed elements for the sustainable operation of gardens were improvement in physical environment and the need for hiring a paid garden, each accounting for 32%. The most important purpose for school gardening was creating educational environments (81.6%). The major source for gaining information on garden management was consultation from acquaintances (67.8%). Schools that utilize plant waste from gardens as natural fertilizers accounted for 45.8% of all schools. Responses to the impact of operating school gardens for educational purpose were positive in all schools as 'very effective' in 63.2% and 'effective' in 36.8%. This study was meaningful in that it intended to identify the current status of the operation of school gardens in elementary schools in Seoul, support the formation of school gardens appropriate for each school with sustainable operation measures, implement a high-quality education program, develop teaching materials, expand job training opportunities for teachers in charge, devise measures to support specialized instructors, and propose the need for a garden management organization.

A Study on Management of Records for Accountability of University student body's autonomy activity - Focused on Myongji University's student body - (대학 총학생회 자치활동의 설명책임성을 위한 기록관리 방안 연구 - 명지대학교 총학생회를 중심으로 -)

  • Lee, Yu Bin;Lee, Seung Hwi
    • The Korean Journal of Archival Studies
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    • no.29
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    • pp.175-223
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    • 2011
  • A university is an organization charged with publicity and has accountability to the community for the operating process. Students account for a majority of members in a university. In universities, numerous creatures are pouring out every year and university students are major producers of these records. However, roles and functions of university students producing enormous amount of records as main agents of universities and focused concentration on produced records have not been made yet. It is reality that from the archival point of view, the importance of produced records of which main agents are university students has been relatively underestimated. In this background, this study attempted approach in archival point of view on records produced by university students, main agents. There are various types of records that university students produce such as records produced in the process of research and teaching as well as records produced in the process of various autonomy activities like clubs, students' associations. This study especially focused on university student autonomy activity process and placed emphasis on accountability securing measures on autonomy activity process of university students. To secure accountability of activities, records management should be based. Therefore, as a way to ensure accountability of unversity students autonomy activity, we tried to present records management systematization and records utilization measures. For this, a student body, a university student autonomy organization was analyzed and a student body of Myongji University Humanities Campus was selected as a specific target. First, to identify records management status, activities and organization and functions of the student body, we conducted an interview with the president of the student body. Through this, we analyzed the activities of the university student body and examined the necessity of accountability accordingly. Also, we derived the types and characteristics of records to be produced at each stage by analyzing the organization and functions of the student body of Myongji University. Like this, after deriving the types of production records according to the necessity, organization and functions of accountability and activities of the student body, we analyzed records management status of the present student body. First, to identify the general process status of activities of the student body, we analyzed activity process by stage of the student body of Myongji University. And we analyzed records management method of the student body and responsibility principal and conducted real condition analysis. Through this analysis, we presented the measures to ensure accountability of a university student body in three categories such as systematization of records management process, establishment of records management infrastructure, accountability guarantee measures. This study discussed accountability on society by analyzing activities and functions of a student body, targeting a student body, an autonomy organization of university students. And as a measure to secure accountability of a student body, we proposed a model for records management environment settlement. But in terms that a student body is an organization operated in one year basis, there is a limit that records management environment is hard to settle. This study pointed out this limit and was to provide clues when more active researches were carried out in the field of student records management in the future through presentation of student body records management model. Also, it is expected that the analysis results derived from this research will have significance in terms of school history arrangement and conservation.

Factors affecting the turnover intention of Industrial Accident Hospital Employees by Job Category (산재병원 구성원들의 직종별 이직의사에 관련된 영향요인)

  • Bang, Yong-Joo
    • Korea Journal of Hospital Management
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    • v.8 no.3
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    • pp.92-117
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    • 2003
  • The purpose of this study was to analyze the characteristics of socio-demographic, organizational conflict and job satisfaction, and to examine the interrelation of influential factors in the intention of turnover. The data for this study were collected through a self-administrated survey with a structured questionnaire to 1,027 subjects from several medical doctor staff members, nursing staff members, administration staff members, pharmacist, and technical expert of eleven hospitals. The data were collected by self-reporting questionnaire from July 29 to September 7, 2002. In this analysis frequency test, t-test, ANOVA, multiple regression were used. The main results of this research is as following; 1. According to socio-demographic characteristics of the respondent's level of the intention of turnover was higher in a doctor staff members than others, for females than males, and had worked for 5-10 years in hospitals. Also, the intent to turnover was generally higher younger workers than long terms workers. 2. According to the organizational conflict characteristics as the respondents who got less conflict experience in the organization, their level of the intention of turnover was higher. And, technical conflict experiences were expressed greater than hierarchical conflict experiences. 3. According to the job satisfaction characteristics as his or her satisfaction that is about the promotion, working itself, salary, and fellowship in the organizational was higher, the level of the intention of turnover was lower. 4. According to the result of Multiple Regression for the doctor staff members in general hospitals rather than special hospitals was negatively correlated with the satisfaction of working itself while hierarchical conflict factors in the organizational conflict characteristics was positively correlated with the intention of turnover. For the nursing staff members the job satisfaction for the working itself, salary were negatively correlated with the intention of turnover. For the administration staff members as the job satisfaction for the working itself was negatively correlated with the intention of turnover. For medical and pharmacy staff members as more working experience, correlation with the intention of turnover was negative. Besides, as the job satisfaction for the working itself and the fellowship was negatively correlated with the intention of turnover. For the skill and technicians, the job satisfaction for the working itself, promotion were negatively correlated with the intention of turnover. The above indicate that job satisfaction and promote their ability and form a good relationship with organization members were very important to decrease the intention of turnover. This study identified the major effective factors of the intention of turnover and analyzed the differences among the job category. In that respect, it is significant for the study to be able to provide a reference for managing hospital of industrial accident and organizational development. However, this study has a problem, which is not to identify a valuable model for examining the relationship between organizational factors such as organizational conflict, job satisfaction, and intention of turnover. Therefore, further study is needed and strengthened in the field of intention of turnover for hospital for industrial accident.

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The Comparative Study on Performance Evaluations of Social Service Delivery Types (사회서비스 공급유형별 성과평가 비교 : 노인관련 사회서비스를 중심으로)

  • Seo, Jeong-Min;Kim, Nang-Hee
    • Journal of Digital Convergence
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    • v.14 no.5
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    • pp.39-46
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    • 2016
  • The history of Social service is above 10 years. Owing to corresponding to the user's needs social services sector is expanding. And, to deal with them, the social delivery systems has been changed. Traditional social welfare delivery system is provided by public facilities and private facilities. On the other hand, Social Services is made up of the traditional social welfare delivery system and new delivery system which is composed of profit organizations and non-profit organizations. Considering this, Study attempted to compare the performance evaluation of supply type-profit and non-profit social service organizations. Performance evaluation method was applied to net income, except for expenditure in total revenue. Net income difference between profit organization non-profit organization was assessed by T-test. We conclude that the two population means are different at the 0.05 significance level. Looking in detail, the non-profit organizations were found to be higher than the non-profit organizations, labor costs, operating costs, facility cost and consumable costs, but part of the business expense costs, the non-profit organizations was higher than the profit organizations.

Development of Multiwire Proportional Counter for Measurement of Environmental-level Alpha Particles (환경준위 알파입자측정을 위한 다중선 비례계수기 개발(I))

  • Oh, Pil Jae;Park, Tae Soon;Lee, Min Kie;Kim, Kyung Hwa
    • Analytical Science and Technology
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    • v.9 no.3
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    • pp.262-269
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    • 1996
  • The muiltiwire proportional counter for the measurement of low-level and environmental $\alpha$ particles emitting nuclides was developed. External dimension of the devloped multiwire proportional counter is $350{\times}290{\times}30mm$ and the sensitivity area is $250{\times}200mm$. The wall material of the detector was selected the stainless steel to prevent the deformation by external impact and to obtain minimum background. The anode and cathode wires were used the stainless steel material of diameter $50{\mu}m$. The spacing of each wires are 10.0mm, 5.0mm and the numbers of total wire are 21, 42 lines, respectively. The multiwire proportional counter was designed that the measurement source is placed within the detector to prevent the wall absorption effect and the efficiency variation by various source heights. The characteristics of the developed detector have been investigated to obtain the plateau, operating voltage, background, counting efficiency, position sensitivity and energy resolution etc. For the $^{241}Am$ nuclide, the calculated LLD(Lower Limit of Detection) is 5.0mBq/L which is lower than 40mBq/L of recommended LLD value by ISO(International Organization for Standardization).

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International Tendencies for Estavlishing a Microbiogical Standard for Food (식품의 미생물 규격기준의 국제적동향)

  • 신광순
    • Journal of Food Hygiene and Safety
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    • v.1 no.1
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    • pp.77-95
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    • 1986
  • In 1962 the governing bodies of FAO and WHO approved the establishment of a joint FAO/WHO Food Standards Programme, the creation of a jointly sponsored body to be known as the Codex Alimentarius commission to implement the Programme. It can reasonably be claimed that the Commission has assumad the leading role in establishing internation food standards throughout the world. The Codex Committee of Food Hygiene has received much advice and assistance from other international organization which have been working in this field for a number of years. In particular, it has received valuable background documentation from the International Commission on Microbiological Specifications for Foods(ICMSF) which was set up by the International Association of Microbiological Societies(IAMS), and also from the International Organization for Standardization (ISO). Nevertheless, in spite of the information supplied by governments and research bodies in this field, microbiological standards have proved to be a highly controversial subject from the point of view of Codex standards. When it is decided to establish a microbiological standard for a food or class of foods, the following technical and administrative aspects must be considered: 1) The standard should be based on factual studies and serve one or more of the following objectives: (1) to determine the conditions of hygiene under which the food should be manufactured; (2) to minimize the hazards to public health; (3) to measure the keeping quality and storage potential of the food 2) The standard should be attainable under practicable operating and commercial conditions and should not entail the use of excessive heat treatment or the additions of extra preservatives. 3) The standard should be determined after investigation of the processing operation. 4) The standard should be as simple and inexpensive to administer as possible, the number of tests being kept to a minimum. 5) Details of methods to be used for sampling, examining and reporting should accompany all published microbiological standards. 6) In establishing tolerance levels for the permissible number of defective samples, allowance should be made for sampling and other variations due to differences in the laboratory methods. The following additional points should be kept in mind: 1) It is not satisfactory to establish one set of microbiological standards for a miscellaneous group of foods, such as“frozen foods”or“precooked foods”. 2) Microbiological standards should be applied first to the more hazardous types of food on the basis of experience of expected microbiological levels, taking into account variations in composition, processing procedures, and storage. 3) When a standard is established, there should be a definite relationship between the standard and the hazard against which it is meant to protect the public. 4) The sensitivity, reliability, and reproducibility of the sampling and analytical methods should be compared in different laboratories and the methods to be used should be specified in detail as part of the standard. 5) Tolerances should be included in the standard to account for inaccuracies of sampling and analysis. 6) Standards should be applied on a voluntary basis before compliance is made mandatory.

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An Analysis of the Effects of Large-scale Retailer Operation Regulations on Agriculture and Fisheries (대형 유통업체 영업 규제가 농수산업에 미치는 영향 분석)

  • Kim, Dong-Hwan;Ryu, Sang-Mo
    • Journal of Distribution Science
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    • v.12 no.2
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    • pp.73-79
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    • 2014
  • Purpose - The Korean government has revised the distribution industry development law to regulate large-scale retailer operations to protecting medium- and small-scale retailers and traditional markets. According to the revised law, large-scale retailers must follow regulations on operating hours and compulsory store closures two days per month. Based on the revised distribution industry development law, most local governments regulate operation hours and they have adopted compulsory closure programs for large-scale retail stores. However, it is argued that fresh food producers suffer from a decrease in sales based on the compulsory closure of stores operated by large-scale retailers. Large-scale retailers reduce their fresh food orders from agricultural and fishery producers because of the compulsory store closures. Fresh food producers also suffer from a decrease in prices because reduced orders lead to a decrease in auction prices based on the availability of excess goods in wholesale markets. This paper investigates the effects of operation regulations for large-scale retailers on agricultural producers by surveying agricultural and fishery producer organizations. Research design, data, methodology - A survey was conducted on 117 producer organizations of fruits and vegetables, cereals, fisheries, and livestock products from September 10 to October 4, 2012. Survey items are annual sales, shares of sales accounted for by large-scale retailers, reduction of orders and prices from large-scale retailers, methods to deal with the sales reduction, unfair trade practices of large-scale retailers, opinion of the large-scale retailer regulations, and so on. The average sales of the sampled producer organizations are 13.7 billion won and the average share of sales accounted for by large-scale retailers is 35.4%. Results - Survey results show that the sample producer organizations' sales decreased 10.1% because of the compulsory closures of stores operated by large-scale retailers. It is estimated that the total sales of producer organizations decreased 371.2 billion won because of the regulations on the operation of large-scale retailers. In addition to the direct effect of a sales decrease due to order reduction, agricultural and fishery producer organizations suffered from the secondary effect of price reduction in wholesale markets. When orders from large-scale retailers decreased, most agricultural and fishery producer organizations shipped redundant products to wholesale markets, decreasing auction prices. It was estimated that the price received decreased 21.9% when sold in other marketing channels. As producer organization sales decreased, it was reported that the labor force employed by producer organizations also decreased by 15.1%. Therefore, we can conclude that the regulations for large-scale retailer operations resulted in negative impacts on agricultural producers. Conclusions - Although the sales reduction due to the regulations for large-scale retailer operations are not great, the cumulative effects due to the continued compulsory closure of stores operated by large-scale retailers could be great. This paper suggests governmental programs that could help agricultural producer organizations to find new and effective marketing channels such as direct marketing, farmers' markets, exports, Internet shopping, and so on.