• Geomechanics and Engineering
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• 제12권6호
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• pp.1003-1020
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• 2017

Estimation of groundwater inflow into underground opening is of critical importance for the design and construction of underground structures. Groundwater inflow into a pilot underground storage facility in China was estimated using analytical equations, numerical modeling and field measurement. The applicability of analytical and numerical methods was examined by comparing the estimated and measured results. Field geological investigation indicated that in local scale the high groundwater inflows are associated with the appearance of open joints, fractured zone or dykes induced by shear and/or tensile tectonic stresses. It was found that 8 groundwater inflow spots with high inflow rates account for about 82% of the total rate for the 9 caverns. On the prediction of the magnitude of groundwater inflow rate, it was found that could both (Finite Element Method) FEM and (Discrete Element Method) DEM perform better than analytical equations, due to the fact that in analytical equations simplified assumptions were adopted. However, on the prediction of the spatial distribution estimation of groundwater inflow, both analytical and numerical methods failed to predict at the present state. Nevertheless, numerical simulations would prevail over analytical methods to predict the distribution if more details in the simulations were taken into consideration.

• The Korean Journal of Physiology and Pharmacology
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• 제20권1호
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• pp.75-82
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• 2016

Paroxetine, a selective serotonin reuptake inhibitor (SSRI), has been reported to have an effect on several ion channels including human ether-a-go-go-related gene in a SSRI-independent manner. These results suggest that paroxetine may cause side effects on cardiac system. In this study, we investigated the effect of paroxetine on Kv1.5, which is one of cardiac ion channels. The action of paroxetine on the cloned neuronal rat Kv1.5 channels stably expressed in Chinese hamster ovary cells was investigated using the whole-cell patch-clamp technique. Paroxetine reduced Kv1.5 whole-cell currents in a reversible concentration-dependent manner, with an $IC_{50}$ value and a Hill coefficient of $4.11{\mu}M$ and 0.98, respectively. Paroxetine accelerated the decay rate of inactivation of Kv1.5 currents without modifying the kinetics of current activation. The inhibition increased steeply between -30 and 0 mV, which corresponded with the voltage range for channel opening. In the voltage range positive to 0 mV, inhibition displayed a weak voltage dependence, consistent with an electrical distance ${\delta}$ of 0.32. The binding ($k_{+1}$) and unbinding ($k_{-1}$) rate constants for paroxetine-induced block of Kv1.5 were $4.9{\mu}M^{-1}s^{-1}$ and $16.1s^{-1}$, respectively. The theoretical $K_D$ value derived by $k_{-1}/k_{+1}$ yielded $3.3{\mu}M$. Paroxetine slowed the deactivation time course, resulting in a tail crossover phenomenon when the tail currents, recorded in the presence and absence of paroxetine, were superimposed. Inhibition of Kv1.5 by paroxetine was use-dependent. The present results suggest that paroxetine acts on Kv1.5 currents as an open-channel blocker.

• Archives of Plastic Surgery
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• 제32권1호
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• pp.117-123
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• 2005

The reconstructive modalities for vaginal reconstruction include simple dilatation, skin graft, use of intestinal segments and various methods using flaps. However, skin grafting procedure is the most commonly used technique and the McIndoe procedure is a representative technique among skin grafting procedures. McIndoe procedure is easier, faster and has a lower morbidity compared to other techniques. However the conventional McIndoe procedure has several problems such as incomplete vestibule formation, excessive bleeding during dissection, possibility of recto-vaginal or urethro-vaginal fistula formation, late vaginal contracture and discomfort in wearing hard plastic mold for a long time after operation. To solve these problems, the authors modified the conventional McIndoe procedure in several perspectives. The undeveloped vestibule was incised with X-shaped mucosal incision between the urethral opening and posterior margin of the vestibule and deepened by blunt finger dissection to provide a sufficient diameter & length of the neovagina and to minimize bleeding. A sizable medium thickness split skin graft was harvested and wrapped over a roll gauze-filled condom mold. Applying multiple stab incision on the skin grafted condom mold, it was inserted into the prepared neovaginal canal. Distal margin of the skin graft was secured with tips of the mucosal flaps created by X-shaped vestibular incision to prevent accidental extrusion of the skin grafted mold. During last 15 years, we applied this modification to 20 vaginal agenesis patients and investigated results of the 12 patients who could be followed up serially including hematoma formation and skin graft survival rate, size, depth, presence of late contracture, appearance, comfortness, and hygiene of the neovagina. And they were compared with 8 patients of 20 patients who underwent conventional McIndoe procedures. The modified McIndoe procedure revealed lower complication rate, higher patient satisfaction and better functional results.

• 한국진공학회지
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• 제12권2호
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• pp.118-122
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• 2003

저압 MOCVD 장치를 이용하여 선택적 에피 성장 (selective area epitaxy) 기술을 개발하고, 이 기술을 이용하여 InGaAs/GaAs 양자세선(quantum wire) 구조를 성장하였다. $SiO_2$로 선택적으로 마스킹 된 GaAs 기판위에 AIGaAs/GaAs 다충 구조 및 InGaAs/GaAs 양자세선 구조를 저압 MOCVD 방법으로 성장하였다. 매끄러운 사면을 갖고 끝 부분이 뽀쪽한 삼각형 구조의 양자세선 구조가 선택적 에피 성장법에 의해 자발적으로 형성되었다. 선택적 에피층 성장을 위한 최적 조건을 알기 위해 먼저 GaAs/AlGaAs 다층구조에 대하여 여러 가지 성장변수들에 대하여 조사하였다. 성장 변수들은 성장률(growth rate), V/III 비 및 성장온도, 패턴의 정렬 방향 등이다. 양자세선에서 나오는 발광은 975 nm로 분석되었다. 측정 온도가 증가됨에 따라 삼각형 구조의 사면의 양자우물에서 나오는 발광은 급격하게 감소하였다. 그러나 양자세선에서 나오는 발광은 양자우물에서 나오는 발광에 비해 서서히 감소하였고, 50 K 이상의 온도에서는 양자세선에서 나오는 발광의 세기가 더 커졌다.

• Korean Chemical Engineering Research
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• 제46권6호
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• pp.1057-1062
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• 2008

기존 2탑 유동층 공정의 단점을 극복하기 위해 두 개의 기포유동층, 고체분사노즐, 상승관 및 고체재순환관으로 구성된 신개념 2탑 유동층 공정을 적용한 3 kW 매체순환식 가스연소기를 개발하였다. 본 연구에서는 3 kW급 매체순환식 가스연소기에서 고체순환속도에 미치는 고체분사노즐 유속, 유동화속도, 고체층 높이, 고체유입구의 단면적, 층 온도 등의 영향을 고찰하였다. 고체순환속도는 고체층 높이가 증가하고 고체유입구의 단면적이 증가할수록 증가하는 경향을 나타내었으며 유동화속도와 온도의 영향은 크지 않았다. 장기연속운전 가능성을 검토하기 위해 50시간까지 고체순환 장기연속운전을 실증하였다. 두 유동층과 고체재순환관의 압력강하 값이 안정적으로 유지되어 고체순환이 원활하고 안정적으로 유지되는 것을 확인하였다.

• Nuclear Engineering and Technology
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• 제27권3호
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• pp.317-326
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• 1995

증기발생기의 수위제어시스템에 대해 특히 저출력시 수위제어의 문제점을 분석고찰하고 퍼지제어기 법을 기반으로 한 안정되고도 신속한 수위제어에 관한 연구가 주로 수행되었다. 문제해결의 한 방안으로서, 중요 제어변수임에도 불구하고 저출력운전시 저유량구간의 추정불량으로 인해 사용할 수 없는 유량신호를 대신하여 밸브개도를 이용한 대체정보를 채용하였으며 또한 소속함수크기의 유동적인 조정방법을 이용하여 수위오차가 크게 발생한 과도상태시에는 신속한 수위회복이 이루어지도록 하였다. 실제운전환경에서 제시된 제어기를 튜닝 하기 위한 방법으로서 제어성능지수 및 decent method를 이용한 소속함수의 self-tuning 기법을 제시하였다. 원자력 연구소의 연수원에 설치된 교육훈련용 시뮬레이터에서 수행된 실험결과는 제시된 제어기 및 튜닝방법의 안정되고 우수한 성능구현 및 실질적 인 유용성을 보여주고 있다.

• 천문학회보
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• 제41권1호
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• pp.41.3-42
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• 2016

New CCD photometric observations of GX Aur have been made between 2004 and 2015. Our light curves are the first ever compiled and display the variable O'Connell effect. The light variations are satisfactorily modeled by including time-varying cool-spots on the component stars. Our light curve synthesis indicates that the eclipsing pair is an A-type contact binary with parameters of i = 81.1 deg, ${\Delta}T=36K$, q = 0.950 and f = 46%. Including our 25 timing measurements, a total of 83 times of minimum light spanning about 66 yr were used for a period study. It was found that the orbital period of GX Aur has varied due to two periodic oscillations superposed on an upward-opening parabolic variation. The long-term period increase rate is deduced as $+9.636{\times}10^{-10}d\;yr^{-1}$, which can be produced as a mass transfer from the secondary star to the primary at a rate of $3.136{\times}10^{-6}M_{\odot}\;yr^{-1}$, among the largest rates for contact systems. The periods and semi-amplitudes of the two periodic variations are about $P_3=8.7yr$ and $P_4=21.2yr$, and $K_3=0.011d$ and $K_4=0.017d$, respectively. The most reasonable explanation for both cycles is a pair of light-travel-time effects driven by the possible existence of an unseen third and fourth components with projected masses of $M_3=0.91M_{\odot}$ and $M_4=1.09M_{\odot}$ in eccentric orbits of $e_3=0.13$ and $e_4=0.73$. Because no third light was detected in the light curve synthesis, each circumbinary object could be a compact star or a binary itself.

• 대한설비공학회:학술대회논문집
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• 대한설비공학회 2008년도 동계학술발표대회 논문집
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• pp.357-362
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• 2008

This study have goal with reverse engineering for petrochemistry of high pressure ball valve for localization. Ball valve for development accomplished with flow analysis based on provision of ANSI B16.34, ANSI B16.10, ANSI B16.25 In order to localize the petrochemistry high pressure control valve. Numerical simulation using CFD(Computational Fluid Dynamic) in order to predict a mass flow rate and a flow coefficient form flow dynamic point of view. The working fluid assumed the water($H_2O$). The valve inlet and outlet setup a pressure boundary condition. The outlet pressure was fixed by atmospheric pressure and calculated inlet velocity 5m/s. CFD solver used STAR-CCM+ which is commercial code. The result shows change of mass flow rate according to opening and closing angle of valve. Flow decrease observed open valve that equal percentage flow paten which is general inclination of ball valve. The structural analysis used ANSYS which is a commercial code. Stress analysis result of internal pressure in valve showed lower than yield strength. This is expect to need more detail design and verification for stem and seat structure.

• Journal of Plant Biology
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• 제29권1호
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• pp.41-51
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• 1986

The plants of Nicotiana tabacum L. cv. NC2326 were germinated in 10 cm D$\times$20 cm H polyethylene pot, and sand-cultured with Hoagland solution near by the window of laboratory room(26$\pm$5$^{\circ}C$). The growing plants were sprayed with various concentrations of ABA around 9 : 00 a.m. once in every two days for 12 weeks in summer. As the results, frequency of stomatal number, stomatal opening, chlorophyll content, respiration rate, and protein content in the leaves were decreased with the increasing of concentrations of ABA, respectively. The plant growth was inhibited by exogenous ABA, but leaf abscission was not found during the experimental period. The ratio of three to one in chlorophyll a to b was not altered by exogenous ABA. All the stomata were closed within three minutes by 100 $\mu\textrm{g}$ ml-1 ABA and within seven minutes by 1-10 $\mu\textrm{g}$ ml-1 ABA after the spraying of ABA, and then reopended after a few hours in 1-10 $\mu\textrm{g}$ ml-1 ABA and after 24 hours in 100 $\mu\textrm{g}$ ml-1 ABA. The polar movement of chloroplast within the guard cells was found in the higher concentrations of 10 and 100 $\mu\textrm{g}$ ml-1 ABA, but not found in the lower concentrations than 1 $\mu\textrm{g}$ ml-1 ABA. During the night and weak light, it was fond that the inhibition of respiration rate by the higher concentration of ABA was owing to firstly the stomatal closure by the spraying of ABA and secondly the decrease of stomatal frequency by the inhibition of stomatal development with exogenous ABA for the long period of 12 weeks. In the band number of leaf protein by the electrophoresis, most of the protein bands were disappeared by the higher concentration of 100 $\mu\textrm{g}$ ml-1 ABA, but were not altered by the lower concentration of ABA in comparison with control.

• 한국식품과학회지
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• 제16권2호
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• pp.182-184
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• 1984

감마선(線) 조사(照射)와 자연저온(自然低溫)에 의한 송이 저장법(貯藏法) 개발(開發)을 목적(目的)으로 $1{\sim}2.5kGy$ 범위(範圍)의 감마선(線)을 조사(照射)하고 자연저온(自然低溫) 저장고(貯藏庫)에 저장(貯藏)하면서 이화학적(理化學的) 변화(變化)를 조사(調査)하였다. 비조사구(非照射區)에서는 저장(貯藏) 7 일(日)에 97%의 갓이 피었고, 28%의 높은 부패율(腐敗率)을 나타내었으나 적정선량(適正線量)이라고 생각되는 $2{\sim}2.5kGy$ 조사구(照射區)에서는 5%의 갓핌과 $5{\sim}8%$의 낮은 부폐율(腐敗率)을 보였으며, 중량감소(重量減少), texture 및 내부(內部)의 변색(變色)에 있어서도 조사구(照射區)는 비조사구(非照射區) 보다 우수하여 10일(日) 이상(以上)의 저장기간(貯藏期間)을 연장(延長)할 수 있었다. 화학성분(化學成分) 변화(變化)에 있어서는 선량(線量)의 증가(增加)와 더불어 환원당(還元糖)이 약간증가(增加)하였고 ascorbic acid는 감소(減少)하였으며 다른 성분(成分)에 있어서는 별차이(別 差異)가 없었다.