• Title/Summary/Keyword: Opening rate

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Studies on Phenotype of Reproduction and Production of Human Growth Hormone(hGH) with Transgenic Rats I. Changes in Endogenous Grwoth Hormone Secretion and Onset of Puberty in hGH Transgenic Rats (Human 성장호르몬을 도입한 Transgenic Rats의 작출과 번식표현형에 관한 연구 I. mWAP/hGH을 도입한 Rat의 Endogenous GH분비 변화와 성성숙에 미치는 영향)

  • 장규태;김성현;성환후;주학진;박미령;윤창현
    • Korean Journal of Animal Reproduction
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    • v.22 no.2
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    • pp.127-136
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    • 1998
  • A chimeric gene comprising murine whey acidic protein(mWAP) and human growth hormone(hGH) was used to produce transgenic rats express hGH and secrete it into the blood. Two lines of transgenic rats carrying the mWAP/hGH construct were established; High line was characterized by relatively high levels of serum hGH, and low line had relatively low levels. The secretory profiles of rat GH(rGH) as well as hGH, the transgene product, were obtained in transgenic males and females of low line; both hGH and rGH serum levels were flattened with no episodic fluctuations, and the overall mean concentration of rGH was significantly lower than in normal littermates. Although the animals of High line showed an acceles, as assessed by vaginal opening and occurrence of first ovulation, advanced by 7∼8 days in both lines of animals. Accordingly, the body weight at puberty of low line transgenic females was much lower than that of normal littermates, indicating that continuous hGH expression could induce precocious puberty without enhancing the growth rate.

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A Real-Time Inspection System for Digital Textile Printing (디지털 프린팅을 위한 실시간 직물 결점 검출 시스템)

  • Kim, Kyung-Joon;Lee, Chae-Jung;Park, Yoon-Cheol;Kim, Joo-Yong
    • Textile Coloration and Finishing
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    • v.20 no.1
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    • pp.48-56
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    • 2008
  • A real-time inspection system has been developed by combining CCD based image processing algorithm and a standard lighting equipment. The system was tested for defective fabrics showing nozzle contact scratch marks, which are one of the frequently occurring defects. Two algorithms used were compared according to both their processing time and detection rate. First algorithm (algorithm A) was based on morphological image processing such as dilation and opening for effective treatment of defective printing areas while second one (algorithm B) mainly employs well-defined edge detection technique based on canny detector and Zermike moment. It was concluded' that although both algorithms were quite successful, algorithm B showed relatively consistent performance than algorithm A in detecting complex patterns.

Estimation of Probability Density Functions of Damage Parameter for Valve Leakage Detection in Reciprocating Pump Used in Nuclear Power Plants

  • Lee, Jong Kyeom;Kim, Tae Yun;Kim, Hyun Su;Chai, Jang-Bom;Lee, Jin Woo
    • Nuclear Engineering and Technology
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    • v.48 no.5
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    • pp.1280-1290
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    • 2016
  • This paper presents an advanced estimation method for obtaining the probability density functions of a damage parameter for valve leakage detection in a reciprocating pump. The estimation method is based on a comparison of model data which are simulated by using a mathematical model, and experimental data which are measured on the inside and outside of the reciprocating pump in operation. The mathematical model, which is simplified and extended on the basis of previous models, describes not only the normal state of the pump, but also its abnormal state caused by valve leakage. The pressure in the cylinder is expressed as a function of the crankshaft angle, and an additional volume flow rate due to the valve leakage is quantified by a damage parameter in the mathematical model. The change in the cylinder pressure profiles due to the suction valve leakage is noticeable in the compression and expansion modes of the pump. The damage parameter value over 300 cycles is calculated in two ways, considering advance or delay in the opening and closing angles of the discharge valves. The probability density functions of the damage parameter are compared for diagnosis and prognosis on the basis of the probabilistic features of valve leakage.

Development of Hybrid Sol-Gel Coating to Prevent Corrosion of Magnesium Alloys (마그네슘 합금의 방청을 위한 하이브리드 졸-겔 코팅제의 개발)

  • Lee, Dong Uk;Kim, Young Hoon;Moon, Myung Jun
    • Corrosion Science and Technology
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    • v.17 no.1
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    • pp.30-36
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    • 2018
  • The high rate of corrosion of magnesium alloys makes it limited for industrial applications. Therefore, surface treatment is required to enhance their corrosion resistance. In our study, a chemical conversion coating for protecting the corrosion of the magnesium alloy, AZ31B, was prepared by using a phosphate-permanganate solution. The chemical conversion coating had a limited protection ability due to defects arising from cracks and pores in the coating layer. The sol-gel coating was prepared by using trimethoxymethylsilane (MTMS) and 3-glycidoxypropyltrimethoxysilane (GPTMS) as precursors, and aluminum acetyl acetonate as a ring opening agent. The corrosion protection properties of sol-gel and conversion coatings in 0.35wt% NaCl solution were measured by the electrochemical impedance spectroscopy (EIS) and potentiodynamic polarization test. The EIS results indicated that the resistance of the chemical conversion coating with the sol-gel coating was significantly improved through the sol-gel sealed phosphate-permanganate conversion coating. The results of the potentiodynamic polarization test revealed that the sol-gel coating decreased the corrosion current density ($I_{corr}$). The SEM image showed that the sol-gel coating sealed conversion coating and improved corrosion protection.

Drug Release Behavior of Poly($\varepsilon$-caprolactone )-b-Poly( acrylic acid) Shell Crosslinked Micelles below the Critical Micelle Concentration

  • Hong Sung Woo;Kim Keon Hyeong;Huh June;Ahn Cheol-Hee;Jo Won Ho
    • Macromolecular Research
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    • v.13 no.5
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    • pp.397-402
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    • 2005
  • To explore the potential of shell crosslinked micelle (SCM) as a drug carrier, the drug release behavior of poly($\varepsilon$-caprolactone)-b-poly(acrylic acid) (PCL-b-PAA) SCMs was investigated. PCL-b-PAA was synthesized by ring opening polymerization of $\varepsilon$-caprolactone and atom transfer radical polymerization of tert-butyl acrylate, followed by selective hydrolysis of tert-butyl ester groups to acrylic acid groups. The resulting amphiphilic polymer was used to prepare SCMs by crosslinking of PAA corona via amidation chemistry. The drug release behavior of the SCMs was studied, using pyrene as a model drug, and was compared with that of non-crosslinked micelles, especially below the critical micelle concentration (CMC). When the shell layers were crosslinked, the drug release behavior of the SCMs was successfully modulated at a controlled rate compared with that of the non-crosslinked micelles, which showed a burst release of drug within a short time.

A Study of Stress ratio on the Fatigue Crack Growth Characteristics of Pressure Vessel SA516 Street at Low Temperature (저온 압력용기용 SA516강의 응력비에 따른 피로크랙 전파특성에 관한 연구)

  • 박경동;하경준
    • Proceedings of the KWS Conference
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    • 2001.05a
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    • pp.220-223
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    • 2001
  • In this study, CT specimens were prepared hem ASTM SA516 which was used for pressure vessel plates for room and low temperature service. And we got the following characteristics from fatigue crack growth test carried out in the environment of room and low temperature at $25^{\circ}C$, -3$0^{\circ}C$, -6$0^{\circ}C$, -8$0^{\circ}C$, -l$0^{\circ}C$ and -l2$0^{\circ}C$ and in the range of stress ratio of 0.1, 0.3 by means of opening mode displacement. At the constant stress ratio, the threshold stress intensity factor range ΔK$_{th}$ in the early stage of fatigue crack growth ( Region I ) and stress intensity factor range ΔK in the stable of fatigue crack growth ( Region II) was increased in proportion to descend temperature. It assumed that the fatigue resistance characteristics and fracture strength at low temperature is considerable higher than that of room temperature in the early stage and stable of fatigue crack growth region. The straight line slope relation of logarithm da/dN - ΔK in Region II, that is, the fatigue crack growth exponent m increased with descending temperature at the constant stress ratio. It assumed that the fatigue crack growth rate da/dN is rapid in proportion to descend temperature in Region H and the cryogenic-brittleness greatly affect a material with decreasing temperature.e.greatly affect a material with decreasing temperature.

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A study of mixed-mode interlaminar fracture toughness of graphite/epoxy composite (炭素纖維强化 複合材料의 혼합모우드 層間破壞靭性値에 대한 硏究)

  • 윤성호;홍창선
    • Transactions of the Korean Society of Mechanical Engineers
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    • v.10 no.2
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    • pp.198-207
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    • 1986
  • This study investigates interlaminar fracture characteristics of Graphite/Epoxy composite (HFG Graphite/Epoxy) under mode I (opening mode), mode II (sliding mode) and mixed mode loading conditions. The effects on interlaminar fracture toughness due to different fiber orientations on the crack surface are also investigated. The antisymmetric test fixture proposed by M. Arcan is used for this test. Both critical stress intensity foctors and critical energy release rates were determined and several mixed mode fracture criteria were compared to the experimental data. Also fracture surfaces were investigaed to obtain informations on the fracture behaviors of Graphite/Epoxy composite by means of a scanning electron microscope(SEM).

Optimal Design of Thrust Surface Oil Groove of a High Side Scroll Compressor (고압식 스크롤 압축기 스러스트 오일 그루브 최적 설계)

  • Kim, Hyun-Jin;No, Young-Jae
    • Korean Journal of Air-Conditioning and Refrigeration Engineering
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    • v.29 no.3
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    • pp.127-133
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    • 2017
  • Performance analysis has been carried out on a high side scroll compressor that had a fixed scroll equipped with a circular oil groove on its thrust surface. Oil was supplied to the oil groove through an intermittent opening from a high pressure oil reservoir formed inside the orbiting scroll hub. Oil in the groove was then delivered to both suction and back pressure chambers by pressure differentials and viscous pumping action of the orbiting scroll base plate. Mathematical modeling of this oil groove system was incorporated into a main compressor performance simulation program for an optimum oil groove design. The study findings were as follows. Pressure in the oil groove can be controlled by changing its configuration and the oil passage area. With an enlarged oil passage, the pressure in the oil groove heightens due to an increased flow rate, but the pressure elevation in the back pressure chamber is small, resulting in reduced friction loss at the thrust surface between the two scrolls. On the other hand, by increasing the oil passage area, the oil content in the refrigerant flow increases. Considering all these factors, the energy efficiency ratio could be improved by about 3.6% under the ARI condition by an optimal oil groove design.

Impact of Foreign Direct Investment on Power Sector: An Empirical Study with Refrence to India

  • Maran, K.;Anitha, R.
    • East Asian Journal of Business Economics (EAJBE)
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    • v.3 no.1
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    • pp.8-16
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    • 2015
  • In the later quarter of the twentieth century, the need for foreign capital is realized among the various countries of the world. Developing countries especially developed multi-pronged strategies to attract foreign capital into the country. One such strategy is the adoption of liberalization policy. Almost all the developing countries started opening their economy, out of the compulsion, to achieve faster rate of economic growth and development. Even a communist country like China adopted liberalization policy as a strategy for accelerated economic growth during 1979. India also joined the race by 1991, when the government announced the policy of liberalization. The importance of FDI extends beyond the financial capital that flows into the country. The huge size of the market in this sector and high returns on investment are two important factors in boosting FDI inflows to power sector. 100 percent FDI is allowed under automatic route in almost all the sub sectors of power sector except the atomic energy. Major foreign investment is made in this sector during 2000 to 2009 is Mauritius with an investment of US$ 4490.96 i.e., 4.24 percent of the total FDI inflows into the country during the period. The estimation of future FDI flow shows a marginal decline in the year 2010. Then from 2011 to 2015 onwards upward trend of FDI was observed.

A Low-Voltage High-Speed CMOS Inverter-Based Digital Differential Transmitter with Impedance Matching Control and Mismatch Calibration

  • Bae, Jun-Hyun;Park, Sang-Hune;Sim, Jae-Yoon;Park, Hong-June
    • JSTS:Journal of Semiconductor Technology and Science
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    • v.9 no.1
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    • pp.14-21
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    • 2009
  • A digital differential transmitter based on CMOS inverter worked up to 2.8 Gbps at the supply voltage of 1 V with a $0.18{\mu}m$ CMOS process. By calibrating the output impedance of the transmitter, the impedance matching between the transmitter output and the transmission line is achieved. The PVT variations of pre-driver are compensated by the calibration of the rising-edge delay and falling-edge delay of the pre-driver outputs. The chip fabricated with a $0.18{\mu}m$ CMOS process, which uses the standard supply voltage of 1.8 V, gives the highest data rate of 4Gbps at the supply voltage of 1.2 V. The proposed calibration schemes improve the eye opening with the voltage margin by 200% and the timing margin by 30%, at 2.8 Gbps and 1 V.