Single-cell RNA-sequencing (scRNA-seq) data consists of each cell's RNA expression extracted from large populations of cells. One main purpose of using scRNA-seq data is to identify inter-cellular heterogeneity. However, scRNA-seq data pose statistical challenges when applying traditional clustering methods because they have many missing values and high level of noise due to technical and sampling issues. In this paper, motivated by analyzing scRNA-seq data, we propose a novel spectral-based clustering method by imposing different weights on genes when computing a similarity between cells. Assigning weights on genes and clustering cells are performed simultaneously in the proposed clustering framework. We solve the proposed non-convex optimization using an iterative algorithm. Both real data application and simulation study suggest that the proposed clustering method better identifies underlying clusters compared with existing clustering methods.
The purpose of this study was three-folded to suggest the Simplifying Conditions Method (SCM) as a means of task analysis and sequencing of instructional content, to develop teaching-learning materials by analyzing part of the geological time scale of the earth science and finally to analyze the effectiveness of this method. SCM began by simplifying a complex task into the basic components by eliminating various complexities, which produced a simple representative of the entire task. The next step was to relax conditions on the basic version one by one, thereby gradually introducing progressively more complex tasks to the students. This sequential strategy enabled students to understand the task holistically and to acquire authentic skills from very onset of the course. Moreover, Early mastery of skills enhances the effectiveness and efficiency of instruction. The result of this study revealed that instruction through SCM was more effective in developing students' self-directed learning characteristics and academic achievement than instruction through sequential task analysis methodology.
Journal of the Korea Institute of Military Science and Technology
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v.13
no.2
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pp.243-251
/
2010
The military has been putting great efforts into applying data communication on existing voice communication systems being used in NCW(Network Centric Warfare). Data communication will be an effective choice in one of many effort to yield a minimum kill chain, comparing to legacy voice communications, when tactical units conduct their missions. However, the required budget will be enormous, in case of the replacement of a lot of legacy communication systems with new one. As a cost-effective alternative, the tactical data communication systems using the conventional radio systems instead of the development of new radio systems has been proposed. It is mandatory, though, to ensure QoS while maintaining data communication by making use of legacy radio systems already in use. This paper focuses on the performance issues experimented and analyzed for tactical data communication through the legacy radio systems as the first step towards guaranteed QoS. We have conducted various experiments such as the transmission error rate on certain tactical messages, performance evaluation of redundant transfers, the relationship between the transmission frame size and rate of error, the identification of error points in the transmission frame, and techniques to reduce the errors in both hopping and non-hopping modes. As a result of the performance experiments, The adaptive communication module which decides the redundant transmission or the Forward Error Correction(FEC) technique by analyzing channel status and current transmission status(hopping/non-hopping) of the legacy radio should be designed. the FEC technique in non-hopping, and the redundant transmission technique in hopping mode was recommended from the result of experiment with the frame size is 20bytes in non-hopping and 10Bytes frame size in hopping mode.
In case of the optical camera system with an infinite object distance, optical designs different from previous systems are required to speed up the auto-focus. As the number of lens groups is increased due to this, the conventional analytic method found it difficult to calculate the locus, and even the one-step advanced calculation method also had the trouble of taking a lot of time. In this paper, we suggested an analytic method for calculating the zoom loci by analyzing movement of one or two groups for situations corresponding to the given back focal length and effective focal length after taking a spline interpolation for each lens group. With this method, we would not only calculate the analytic zoom loci without iterations in every optical system without placing a limit on the group number at the zoom lens systems with the infinite object distance, but we would also show the utilities of this method through many examples.
Proceedings of the Korean Institute Of Construction Engineering and Management
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2008.11a
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pp.487-490
/
2008
The mixed-use development project like urban regeneration project has been enforced with long period and participation of various stakeholders. For this character, lots of risk could be occurred during the process of project and the project's success or failure depends on the risk management. So the process of identifying and responding to risks in urban regeneration projects should be followed systemically The risk identification phase is the first step to identify risk factors and define risk's character. One of the risk identification methods, the checklist, is the most practical and well-known one. This study suggests the check list that devide risks classified by stakeholders through analyzing tasks of stakeholders and drawing risks. This kind of checklist which handles risk factors classified by stakeholders is an easy tool to identify risks and expected to be effective to find risks for various stakeholders and themselves in the urban regeneration projects.
Although the number of computed tomography(CT) is increasing every year, it is insufficient to establish appropriate workload calculation standards of radiologic technologist to provide optimal medical services to patients, such as patient safety management and infection management. The purpose of this study is to present guidelines for calculating the appropriate workload of radiologic technologist by analyzing the work flow of CT procedures and the time required for CT examination in major hospitals. As for the study subjects and methods, the appropriate process for each step of CT examination was investigated to systematically present the process and time required for the actual examination, and the CT procedure time of 104,105 adult patients and 465 pediatric patients under the age of 6 were analyzed. For the time required, data according to the use of contrast medium, procedure type, and adult/child were collected and compared. The test time of CT examination using contrast medium took about 13 minutes when one radiologic technologist worked and about 9 minutes when two radiologic technologists worked. The time required for the procedures were statistically significant depending on the presence or absence of contrast medium, multi-phase procedure, and patient age (considering pediatric patients). As a result, in order to thoroughly perform patient safety and infection management, the appropriate workload increased by about 40% when there were two radiologic technologists. The limit workload was an average of 32 people per day with one radiologic technologist per 15 minutes, and 48 people per day with two radiologic technologist per 10 minutes. This is a marginal workload, and in the case of procedures that require more time to acquire radiographic images, the interval between reservations should be widened.
Journal of The Korean Association For Science Education
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v.33
no.1
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pp.208-227
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2013
The purpose of this study is to analyze secondary science teachers' planning process for an integrated science lesson. For this study, relevant references were collected from various sources, including literatures, previous studies regarding integrated science education, and individual studies. Two teachers (one from middle school and the other from high school) participated and 'the five-step instructional design' was adopted from former studies in this subject. The teachers were asked to develop an instructional plan based on 'the design' provided. While the consultation provided a framework for an instructional plan, the teachers were asked to take a leading role in terms of selecting the chapter to be taught; analyzing the course structure; and making detailed teaching plans. In the course of consultations, discussions, records, and analysis were organized into a journal. Based on the journal, the aspects of the planning process, including difficulties and problems faced by teachers, were analyzed in-depth. From the study, it could be observed that both high school and middle school teachers face various difficulties in preparing for the integrated science lesson. Among other things, the teachers emphasized the difficulties in the stages of selecting the topic, collecting the relevant information, and restructuring and organizing the lecture contents.
Journal of Korean Home Economics Education Association
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v.30
no.4
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pp.187-207
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2018
The purpose of this study was to develop a teaching-learning plan applicable to high school technology·home economics and home science classes in order to prevent adolescents' dating violence which is one of the serious social problems we are facing lately. This research has following three steps: 1. Analyzing contents and selecting content elements, 2. Developing teaching-learning materials, and 3. Performing a pilot test and making corrections. In the first step, this author analyzes how the contents associated with dating violence are presented in the 2015 curriculum of technology·home economics and the textbooks and reviews related literatures to select content elements necessary to prevent dating violence for those going through adolescence. Based on that, in the second step, this researcher develops a teaching-learning plan for six lessons and then makes it verified by two experienced teachers of home economics. In the last step, the teaching-learning plan for six sessions developed is implemented to two high school classes, and then, based on the results of examining the opinions of the teachers implementing the plan and students about the class, this researcher modifies and complements the parts of the plan showing low applicability to the field and develops the final dating violence prevention teaching-learning plan. In order to prevent adolescents' dating violence, it is necessary to create a social environment safe from violence and provide violence prevention education before they begin to have relationship. This researcher expects that this teaching-learning plan is applied in home economics class and it can contribute to enhancing students' sensitivity about violence and improving their competencies to make wise judgments in problematic situations and cope with them properly.
The purpose of this study was to examine what factors affected patients who suffered from essential hypertension compliance with health behaviors, to help build a successful strategy to step up their compliance with health behaviors, and to seek effective ways to implement health education programs for patients with chronic disease. The subjects in this study were 60 people selected from among the patients who were diagnosed by physicians as having essential hypertension in S General Hospital in the city of P from April 10 through July 30, 2000, after health education was provided four times a month. The quasi- experimental design based on a control group pretest-posttest design was employed. The subjects were divided into three groups of 20 patients each: one was an experimental group to receive education in one-to-one interview, another was an experimental group to receive education as a group, and the third was a control group. The two experimental groups learned the same material through different methods, and the control group was given the same teaching materials and asked to comply with health behaviors on their own without instruction. After the three-week education was implemented in different ways, their compliance with health behaviors was measured. Collected data was analyzed by t-test, paired test, one-way analysis of variance, correlation analysis and regression analysis procedures. The findings of this study were as follows: 1. Concerning the effective type of health education, the group education produced the best results, followed by the one-to-one interviews and the sole use of print media. 2. Regarding the effect of compliance with health behaviors, the group- educated group got the highest score in compliance with health behaviors, but blood pressure lowered more significantly in the individual interview group. And the compliance with health behaviors had a significant negative correlational relationship with both systolic and diastolic blood pressure. 3. Parameter that had most significant correlational relationship with compliance with health behaviors was health locus of control, followed by self-efficacy and health perception. But there was no significant correlational relationship between compliance with health behaviors and knowledge of hypertension. 4. As a result of analyzing the impact of knowledge of hypertension, health locus of control, self-efficacy and health perception on compliance with health behaviors, self-efficacy was found to exercise most influence. Above-mentioned findings suggested that group education or one- to-one discussion would be more effective for health care for hypertension in koreans, as they could serve to have patients realize their own responsibility for health and to motivate their compliance with health behaviors, and there was a need to more positively utilize educational intervention for patients with chronic diseases, which could elevate not only compliance with health behaviors but self-efficacy.
In order to investigate the tendency of general displacements and behaviors with respect to each construction process as well as the applicability of numerical analysis schemes, this research has focused on not only analyzing a variety of field observations made in a NATM tunnel, such as displacement of top and side, stress of shotcrete and axial strength of rock bolt, but also carrying out a series of numerical analyses. It was established from the investigation that the 2-dimensional continuum numerical analysis was the one which could more accurately predict displacement of crown and side in the area of one step excavation (patten, P1-P3), while the 2-dimensional discontinuum analysis was the most suitable scheme to study that of two step excavation (patten, P4-P6). In addition, the 2-dimensional continuum analysis enabled to appropriately predict the axial strength of rock bolt and stress of shotcrete in all the area of the tunnel. Finally, it has been possible to conclude from the study that the 3-dimensional continuum analysis should be applied to inspect the behavior and tendency with respect to each stage of the construction as well as in the case of joints, such as large turnouts where relaxation loads in both of horizontal and vertical direction are piled up.
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