• 한방재활의학과학회지
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• 제30권2호
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• pp.19-35
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• 2020

Objectives The aim of this study is to evaluate the fracture healing effect of Jinmu-tang (JM) on femur fractured rats. Methods Rats were randomly divided into 5 groups (normal, control, positive control, JM extract with low concentration and JM extract with high concentration). All group except normal group went through both femur fracture. Normal and control group received no treatment at all. Positive control group were medicated with tramadol (20 mg/kg) once a day for 14 days. Experimental group was orally medicated with JM extract (10 mg/kg for low concentration, 50 mg/kg for high concentration) once a day for 14 days. In order to investigate fracture healing process, plasma and serum were obtained. Also, micro-computed tomography was conducted to see the frature site visually. Immunohistochemistry for transforming growth factor-β1, Ki67, alkaline phosphatase, runt-related transcription factor 2, receptor activator of nuclear factor kappa-β, tartrate resistant acid phosphatase was conducted to observe bone healing progress after 14 days since fracture occured. Aspartate aminotransferase, alanine aminotransferase, blood urea nitrogen and creatinine levels were measured in plasma, for hepatotoxicity and nephrotoxicity of JM extract. Osteocalcin was measured to observe activity of osteoblast. Results Through Micro-CT, more fracture healing was observed on both experimental group than control and positive control group. Through Hematoxylin & Eosin and safranin O staining showed bone cell proliferation and bone formation in the experimental group. RANK was significantly increased in the experimental groups. JM with high concentration showed statistically significant of TGF-β and Osteocalcin. NO, TRAP and ALP were not significantly changed. Liver toxicity was not significantly observed. Creatinine significantly increased in both experimental groups after 28 days. Conclusions As described above, JM extract showed anti-inflammatory effect, promoted fracture healing by stimulating the bone regeneration factor, and showed little hepatotoxicity and nephrotoxicity. In conclusion, JM extract can promote fracture healing and it can be used clinically to patients with fracture.

• 대한가정학회지
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• 제46권6호
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• pp.89-100
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• 2008

The purpose of this study was to provide basic data for the familial voluntary service of the Healthy Family Center and then verify the effectiveness of its application in order to improve family healthy through a familial voluntary service. Study subjects were both volunteers who belonged to family volunteer corps of 12 Healthy Family Centers. Collected data was analyzed SPSS WIN 12.0 program. The results were as followed. First, a 54.1% of subjects is taking part in a familial voluntary service, while a 45.9% of them is not. Their positive intention of future participation is a 77.4%. The period of participation is from 6 months to two years. The frequency of participation is once or twice a month, and the length of activities per participation is for 3 hours. They have taken part in the service with a variety of public relations, and their motive of participation is by and large selfish. Second, as for the influence of participation in a familial voluntary service upon family healthy, the family healthy of participant group is higher in all the four sub-variables of family healthy than that of other groups. The group of which frequency of participation is once a week is better in family communication than the group of which frequency of participation is once or twice per month. The group of which motive of participation is altruistic is higher in sharing a value system among families than the group of which motive of participation is selfish.

• Asian-Australasian Journal of Animal Sciences
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• 제18권3호
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• pp.314-319
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• 2005

To compare two different schemes, continuous scheme (CS) and discontinuous scheme (DCS), of once-weekly ovum pick up (OPU) with ultrasound-guided follicular puncture technique, Holstein heifers were randomly divided into two groups of five. After characterization of their two normal estrous cycles, the heifers were subjected to consecutive 20 weeks of once-weekly OPU under two schemes: the CS (one week interval between continuous OPU, total 100 OPU sessions performed) and the DCS (OPU fixed to the day 3 and day 10 of each estrus). Then, the status of ovaries and artificial insemination results were observed. On oocyte yield, the total number of punctured follicles using DCS was lower than that using CS, but the mean numbers of punctured follicles and recovered oocytes per session were higher in DCS than CS group. So the total number of recovered oocytes was similar in both groups. There were also no differences in the quality of recovered oocytes, nor in the developmental ability of oocytes fertilized in vitro between groups. The heifers in the DCS group showed regular estrous cycles with stable estrous signs through the periods of before, during, and after OPU, while those in CS group showed longer estrous cycles and less estrous signs during and/or after OPU compared with before period. Furthermore, the mean number of inseminations required for obtaining pregnancy after completion of the experiments was lower in DCS than CS group. The research demonstrates that similar quantity and quality oocytes can be achieved, and the side effects on donors are lower in DCS that needs fewer OPUs than CS group, and DCS is superior to CS.

• 성인간호학회지
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• 제25권1호
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• pp.62-73
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• 2013

Purpose: This study was conducted to examine the effects of tailored supportive education on physical, psychological status and quality of life in the patients with congestive heart failure (CHF) who had not participated previously in cardiac rehabilitation program. Methods: This study was used a non-equivalent control pre-post design, conducted on 64 CHF patients under medical treatment in a hospital. The experimental group (n=31) received the tailored supportive educational program (once 1~2 days before discharge and 6 times after discharge through outpatient visits or telephone contact: once every week for the first 4 weeks after discharge and once every 2 weeks for the remaining 4 weeks). The control group (n=33) received a traditional discharge education. Data were analyzed using descriptive statistics, ${\chi}^2$-test, Fisher's exact test, t-test and repeated measure ANOVA using the SPSS/ WIN 18.0 program. Results: Participants in the experimental group showed the significantly increased scores of the quality of life (F=16.01, p<.001), and the significantly decreased scores of physical function (F=7.27, p=.009), depression (F=8.25, p=.006) and anxiety (F=4.11, p=.047), when compared to those of the control group. Conclusion: The findings indicated tailored supportive education was an effective intervention care in physical, emotional status and quality of life for CHF patients.

• 한국식품과학회지
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• 제22권7호
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• pp.780-785
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• 1990

유채박 단백질의 효과적인 추출 및 정제공정을 확립하기 위하여 추출용매를 비교했으며, 1% SHMP 용매로 추출한 후 등전침전, 산세척, UF농축 처리에 의하여 정제한 단백질의 수율 및 glucosinolate와 phytate 잔존량을 조사하였다. 추출조건은 1% SHMP(pH 8.0) 용매가 가장 적당하였으며, glucosinolate 및 phytate 제거를 위한 정제효과 면에서는 2회 산세척시와 1회 산세척 및 UF(100K) 농축 처리한 공정이 가장 효과적 이었다. 수율과 단백질 함량은 2회 산세척의 경우는 37.1% 및 75.3%이었으며, 1회 산세척과 UF(100K) 농축의 경우는 42.1% 및 72.4%였다. 따라서 glucosinolate와 phytate 제거효과와 단백질의 수율면을 고려한 결과 가장 효과적인 정제공정은 등전침전${\rightarrow}$1회 산세척(pH 3.5)${\rightarrow}$중화(pH 7.5)${\rightarrow}$ UF(100K) 농축 처리하는 방법이다.

• 복식문화연구
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• 제22권2호
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• pp.300-312
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• 2014

This study seeks to offer practical suggestions for manufacturing jacket lining patterns through research on menswear brands. A researcher conducted interviews with a survey instrument targeting 12 menswear brands. To analyze the data, descriptive statistics were obtained using SPSS 18.0. The main findings were as follows. First, regarding lining production, most menswear brands were found to provide jacket lining patterns to their subcontractors, and pattern makers were found to design lining patterns based on their own know-how. The most important factor in the production of jacket lining patterns is whether linings are cut more than once during the sewing process. For suit jackets, linings are cut more than once, and for casual jackets, linings are cut once. Second, with regard to jacket production for different jacket styles, most menswear brands were found to use patterns that include seam allowance. Partial linings showed differences in terms of the methods used to sew edges and attach linings to the outer shell. Third, extra space in jacket lining patterns varied according to style. Jacket lining patterns for suit jackets and casual jackets showed differences in extra space in the following areas: the parts that cover the chest(suit jacket linings: 5.6cm, casual jacket linings: 2.4cm), the parts that cover the waist(suit jacket linings: 3.8cm, casual jacket linings: 1.3cm), hem(suit jacket linings: 2.7cm, casual jacket linings: 1.3cm), and bicep(suit jacket linings: 2.7cm, casual jacket linings: 1.1cm). However, extra space in the sleeve hems was identical for the two styles(suit jacket linings: 0.1cm, casual jacket linings: 0.1cm). Therefore, this research suggests that clothing manufacturers design linings in accordance with the jacket lining production style.

• Journal of Ginseng Research
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• 제48권2호
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• pp.181-189
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• 2024

Background: Cigarette smoke is generally accepted as a major contributor to chronic obstructive pulmonary disease (COPD), which is characterized by emphysematous lesions. In this study, we investigated the protective effects of Korean Red Ginseng (KRG) against cigarette smoke condensate (CSC)-induced emphysema. Methods: Mice were instilled with 50 mg/kg of CSC intranasally once a week for 4 weeks, KRG was administered to the mice once daily for 4 weeks at doses of 100 or 300 mg/kg, and dexamethasone (DEX, positive control) was administered to the mice once daily for 2 weeks at 3 mg/kg. Results: KRG markedly decreased the macrophage population in bronchoalveolar lavage fluid and reduced emphysematous lesions in the lung tissues. KRG suppressed CSC-induced apoptosis as revealed by terminal deoxynucleotidyl transferase deoxyuridine triphosphate nick-end labeling staining and Caspase 3 immunohistochemistry. Additionally, KRG effectively inhibited CSC-mediated activation of Bcl-2-associated X protein/Caspase 3 signaling, followed by the induction of cell survival signaling, including vascular endothelial growth factor/phosphoinositide 3-kinase/protein kinase B in vivo and in vitro. The DEX group also showed similar improved results in vivo and in vitro. Conclusion: Taken together, KRG effectively inhibits macrophage-mediated emphysema induced by CSC exposure, possibly via the suppression of pro-apoptotic signaling, which results in cell survival pathway activation. These findings suggest that KRG has therapeutic potential for the prevention of emphysema in COPD patients.

• 한국농촌간호학회지
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• 제15권1호
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• pp.9-15
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• 2020

Purpose: The purpose of this study was to examine the effectiveness of smartphone use to enhance self-efficacy and decrease loneliness in elders through communication using the SNS Program Methods: Participants in this study were assigned to the experimental group (25) or control group (25). Data were collected from June 3 to July 12, 2019. For this study, the communication Program through SNS was run once for a total of 12 sessions. All data were analyzed using SPSS version 18.0 program, 𝑥² test, t-test, Repeated Measure ANOVA and Fisher's exact test. Results: It was found that H1 was supported (z=-4.12, p=.005) as "the experimental group participating in the communication Program through SNS had greater self-efficacy than the control group". H2 was supported as "the experimental group participating in the communication Program through SNS had less loneliness than the control group", (z=3.20, p<.001). Conclusion: This basic information may be used as an intervention on communication Program through SNS. Findings suggest the necessity of improving self-efficacy and reduction of loneliness through an intervention communication Program through SNS.

• 기술사
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• 제35권4호
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• pp.68-73
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• 2002

Almost every industrial plant or building has their own boiler systems, so boilers are often called "kinds of social infrastructures"In Korea, We have many indistinct problems on efficient operations of industrial boiler systems. In this paper, to elevate thermal operation efficiency and to diminish air pollutions of the boilers, especially in urban area, at present, "The muliple installation systems of small type once through boiler(gas fired)" are suggested.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2004년도 학술대회 논문집 전문대학교육위원
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• pp.92-95
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• 2004

Power transformer is an important apparatus in transforming and delivering the power in a power system. It shows less accident ratio than other system apparatus, but once the accident occurs, it causes long-term operation stoppage and economic loss. It brings high bad spillover effects. Therefore, the role of protective relaying, which is to prevent internal fault a power transformer is highly important. This study proposed advanced algorithm that can clearly determine internal fault of the power transformer and magnetizing inrush, through numerical analysis by using the terminal voltage and input output current.