• Journal of Physiology & Pathology in Korean Medicine
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• v.18 no.2
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• pp.451-456
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• 2004

Based on the data from our previous studies, four new diabetic remedies were composed with the addition of Coicis Semen into Okchun-san (OCH), Commelinae Herba into Gangsim-tang (GST) , Scrophulariae Radix into Sunki-san (SKS), and Erythrinae Cortex into Yukmijihuang-hwan (YMG). The water extracts of these new remedies were treated in 3T3-L1 fibroblasts and adipocytes in order to investigate insulin-like substances and insulin sensitizers, respectively. With and without differentiation inducers, unmodified SKS (SKS-O) treatment induced 3T3-L1 fibroblasts into adipocytes more than the control. However, without inducers, YMG treatment, but not SKS, induced the differentiation more than the control among modified remedies. Without inducers, SKS, OCH as well as YMG increased the induction of differentiation from 3T3-L1 fibroblasts into adipocytes, compared to the control. The treatment of OCH and YMG with 1 ng/mL insulin increased glucose uptake much more than only insulin 1 ng/mL treatment. Thus, OCH and YMG contained increased insulin actions. In conclusions, the modified remedies, OCH and YMG, contained insulin-like substances and insulin sensitizers, and they can be improved the hypoglycemic effects.

• Journal of Mushroom
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• v.13 no.3
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• pp.181-184
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• 2015

Mushroom have long been valued as highly nutritious and tasty foods in many societies throughout the world. It is known for biological activities including anti-inflammatory and anti-oxidative potential. However little is known about anti-cancer property. In this study, we investigated the anti-prostate cancer activity of mushrooms. For that, eight kinds of mushrooms such as, T. matsutake, S. crispa, G. lucidum-US, G. lucidum-AS, C. cardinalis-BR, G. frondosa, P. linteus, U. esculenta were extracted with hot water. Among them, three kinds of mushrooms including T. matsutake, G. lucidum-US and C. militaris-BR extracts inhibited prostate specific antigen (PSA) expression in prostate cancer cell, LNCaP. These results demonstrate that some of mushrooms inhibited PSA expression suggesting that the mushrooms might be a candidate for the treatment of prostate cancer.

• Journal of the Korean Society for Library and Information Science
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• v.49 no.1
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• pp.423-441
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• 2015

The results of this study are as follows. Firstly, out of existing manuscripts of Baeggokjib, the one possessed by Sang-hyun Kim and the one possessed by Jonkyunggak, Sungkyunkwan University shows reading reaords. Secondly, as a result of the analyses of the differences between Doksoogi and Gomoonsamshibyookdoksoogi, in terms of 1) order of records 2) the difference in the number of old texts included in the mentioned reading records 3) the difference in the title of old text, 4) the difference in records of reading times, they were revised and rearranged to Doksoogi after the record of Gomoonsamshibyookdoksoogi. Thirdly, as a result of investigations and analyses of 36 types of old texts recorded in Dogsoogi, it was found out that 1) in terms of contents, he mainly read literary books 2) in terms of style of literary books, he read mainly prose, preface, epistle, idle stories, funeral orations, etc. 3) in terms of authors, he read the old texts of Han Yoo who was the literary person during Tang Dynasty 4) Deuk-shin Kim read tend to read mainly old texts instead of single books.

• Herbal Formula Science
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• v.25 no.1
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• pp.103-113
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• 2017

Objectives : Korea and China are applying different conversion standards for weight in traditional medicine books. This study aims to research and suggest how to convert the units of weight in old traditional medicine classics into the contemporary unit of grams. Methods : Historical documents of Korea and China were used to review the process in which weights and measures changed in each country and the manners in which the Chinese units of weight were introduced to Korea. Results : Weights and measures changed with time. They became almost standardized by the period of Song in China, when coins played the most crucial role, and it was introduced to Korea. Donggaryang, the standard container for weights and measures in ancient China, Gaewontongbo, a coin in Tang, Sangpyeongtongbo, a coin in Joseon, and a scale in Joseon were used as strong foundations for conclusion from literature review. Weight of a 1-don(coin) in the time a traditional medicine books were written was used as a unit of weight in those books. Sangpyeongtongbo, a 1-don coin in Joseon, weighs 4 grams on average. Conclusions : Since the current conversion of 1-don coin into 3.75 grams is not supported by literature review, it is suggested that 1-don(coin) as a unit of weight in traditional medicine books of Joseon, may be better converted into 4 grams, while that of China is converted to 3.73 grams.

• CELLMED
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• v.7 no.3
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• pp.13.1-13.10
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• 2017

Nutrition is one of the factors influencing cognitive functions. But, the role of nutrition on cognitive functions within the elderly is recognized to a lesser degree. The aim of this academic endeavor was to analyze the affiliation between nutritional status and cognitive functions of the elderly in Korea. 316 subjects, of 114 male and 201 female aged above 65 years, were gathered from university hospital clinics, Elderly Welfare Centers, and Health Welfare Centers located in the district of Seoul, Gyeonggi province, and Incheon in Korea. The cognitive function was tested by the Korean-Mini Mental State Examination (K-MMSE) questionnaire. Nutrition intake was assessed by a 24-hour recall, a food frequency questionnaire (FFQ). Nutrition adequacy and quality were assessed by the Nutrition Screening Initiative (NSI) checklist, the nutritional adequacy ratio (NAR), and the mean adequacy ratio (MAR). The elderly with normal cognitive function status displayed significantly higher levels of calcium, riboflavin, thiamin, folate, vitamin C, vitamin E, vitamin B6, phosphorous, potassium, iron, niacin, zinc, animal fat, animal protein, polyunsaturated fatty acids, total protein, vegetable oil, vegetable protein, fiber than levels of the elderly with moderate cognitive impairment. The K-MMSE score positively correlated with of high consumption of pork, white radish, sea mustard, tomato, tangerine, grape, apple, and ice cream, and K-MMSE was negatively associated with high intake of potato, anchovy, fish cake, and mushroom. The findings suggest that nutritional status is affiliated with cognitive function within the elderly of Korea. The consumption of variety of foods and nutrients ensures adequate cognitive function in the Korean elderly.

• The Journal of Internal Korean Medicine
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• v.38 no.5
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• pp.658-667
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• 2017

Objectives: This is a case report regarding the effect of Korean traditional medicine on vision disorder and quadriplegia in a patient with neuromyelitis optica. Methods: We treated a patient who was diagnosed with neuromyelitis optica with Korean traditional medicine, including acupuncture, moxibustion, and herbal medicine (Gigugyanghyeol-tang gamibang) for 106 days. We evaluated the patient with the International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI), Modified Barthel Index (MBI), Modified Ashworth Scale (MAS) Grade, and Numeric Rating Scale-11 (NRS-11). Results: After treatment, the patient's symptoms were improved. The ISNCSCI scores increased from 42 to 66 in motor score, from 152 to 196 in sensory score, and from A to D in the ASIA impairment scale; the MBI score increased from 9 to 33, while the score of the MAS Grade decreased from I+ to I, and the NRS-11 scores of vision disorder, spasticity, and tingling decreased from 10 to 7, 3, and 2-3, respectively. Conclusions: Korean traditional medicine may be effective for treatment of vision disorder and quadriplegia in patients with neuromyelitis optica.

• The Journal of Internal Korean Medicine
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• v.39 no.5
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• pp.853-862
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• 2018

Objectives: The aim of this study was to report on the Korean medicine treatment of a case of a cerebellar infarction patient suffering from vertigo, nausea, and vomiting. Methods: We applied herbal medicine (Yangjin-tang), acupuncture, and moxibustion to the patient, who was admitted to hospital for 51 days. Clinical symptoms were assessed with a numeral rating scale (NRS) and neurologic examination. Results: After treatment, the vertigo, nausea, and vomiting symptoms were improved, and the NRS showed improvement. Conclusions: This case shows that Korean medicine treatments are effective in relieving the symptoms of cerebellar infarction patients experiencing vertigo, nausea, and vomiting.

• Journal of Korean Medical classics
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• v.13 no.1
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• pp.17-43
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• 2000

This study on the conception of Pyo Bon expressed in Hwang Jae Nai Kyung was summarized as follows: 1. The conception of Pyo Bon in the Yi Jung Byun Gi Lon(移精變氣論) and Tang Eak Yo Le Lon(湯液료醴論) of So Moon(素問) is that Pyo means the doctor and Bon means the disease. The Pyo Bon of this chapter has a meaning of time, namely first and last. 2. The conception of Pyo Bon in the Soo Yul Hyul Lon(水熱穴論) of So Moon is that Pyo means the lung and Bon means the kidney. The Pyo Bon of this chapter has a meaning of space, namely the upper and lower sides. 3. The conception of Pyo Bon in the Pyo Bon Byung Jun Lon(標本病傳論) of So Moon is that Pyo means a earlier disease and Bon means a later disease. The Pyo Bon of this chapter has a meaning of time, namely first and last. 4. The conception of Pyo Bon in the Chun Won Gi Dae Lon(天元紀大論), Yug Mi Ji Dae Lon(六微旨大論) and Ji Jin Yo Dae Lon(至眞要大論) of So Moon is that Pyo means a Yug Gi(六氣), namely wind, cold, heat, dampness, dryness, fire and Bon means a Sam Eum Sam Yang(三陰三陽), The Pyo Bon of this chapter includes a meaning of time and space. 5. The conception of Pyo Bon in the Sa Jun(師傳) of Yung Chu(靈樞) is that Pyo means a inside of the body and Bon means a outside of the body. The Pyo Bon of this chapter a meaning of space, namely the inside and outside. 6. The conception of Pyo Bon in the Wi Gi(衛氣) of Yung Chu is that Pyo means the end of limbs and Bon means the part of head, face, chest, abdomen, back. The Pyo Bon of this chapter has a meaning of space, namely center and circumference.

• Journal of Oriental Neuropsychiatry
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• v.32 no.3
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• pp.141-154
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• 2021

Objectives: Pharmacopuncture is a Korean medicine treatment that combines acupuncture and herbal medicines. The aim of this study was to investigate the current usage status of pharmacopuncture for insomnia among Korean medicine doctors (KMDs). Methods: We conducted a self-reporting online survey targeting KMDs from February 23 to March 15, 2021 with cooperation of the Association of Korean Medicine. Responses of 957 KMDs were analyzed. Results: Types of pharmacopuncture mainly used in treatment for insomnia were placenta pharmacopuncture and Hwangryunhaedok-tang pharmacopuncture. Cephalic and facial region were preferred as the treatment site. For one treatment, total usage of pharmacopuncture was more than 0.5 cc but less than 1 cc. Among respondents, the largest number of respondents thought that clinical experience and patient symptoms were important as selection criteria of acupoints using Pharmacopuncture for insomnia. Average treatment duration of using Pharmacopuncture for insmonia was more than 4 weeks. Most KMDs preferred treatment for one to four times a week regarding the treatment cycle. The use of Pharmacopuncture for insomnia was recognized as having a good effect, although other KMDs were concerned about the insufficient evidence and the high cost due to non-reimbursement of pharmacopuncture therapy. Conclusions: In order to activate pharmacopuncture treatment for insomnia, it is necessary to secure effectiveness and safety through basic research, create evidence through clinical research, and reduce costs for patients.

• Asian-Australasian Journal of Animal Sciences
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• v.31 no.12
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• pp.1974-1979
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• 2018

Objective: This study compared fatty acid compositions and antioxidant activities of high-preference cuts (loin, tenderloin, and rib) and low-preference cuts (brisket, topside, and shank) of Hanwoo (Bos taurus coreanae) cows to obtain potentially useful information for promoting the consumption of various low-preference cuts. Methods: Individual 500 g samples of fresh beef were collected from each of the six cuts from 10 Hanwoo cows (quality grade 1) and immediately freeze-dried. The dried samples were evaluated for fatty acid composition, free radical scavenging activities (hydroxyl, alkyl, and 2, 2'-diphenyl-1-picrylhydrazyl [DPPH] radical), and antioxidative enzyme activities (glutathione peroxidase [GPx], glutathione-S-transferase [GST], and superoxide dismutase [SOD]). Results: The percentages of total polyunsaturated fatty acids were significantly higher in low-preference cuts than in high-preference cuts (p<0.05). Hydroxyl, alkyl, and DPPH radical scavenging activities were significantly higher in low-preference cuts than in high-preference cuts (p<0.05). In addition, the activities of antioxidant enzymes, such as GPx, GST, and SOD, were significantly higher in low-preference cuts compared with high-preference cuts (p<0.05). Conclusion: These results may influence consumers to include more low-preference cuts in their selections based on the nutritional facts, which could help to balance the beef market in South Korea.