• CELLMED
• /
• v.6 no.2
• /
• pp.8.1-8.2
• /
• 2016

The purpose of this article is to argue that Arirang, Korean traditional music, could be used for healing purposes for Koreans. Music may be a medicine for curing both the body and mind. That is the soul of folksong. Arirang is a representative folksong in Korea. Koreans thought that listening to Korean traditional songs and singing them have healing powers because it makes people happier. When Koreans listen to Arirang, slowly as if they are mass hypnotized, Koreans calmed down because they think of mother's bosom while listening to Arirang. Also, Koreans find comfort in listening and singing to Arirang. The song's tune is catchy and its lyrics are moving. The song of Arirang was sung from long ago by Koreans. Therefore, it will continue forever as long as Koreans exist.

• CELLMED
• /
• v.6 no.2
• /
• pp.10.1-10.3
• /
• 2016

Arirang has quite a long history in Korean music. Arirang means the heart is tingling. Jeongseon Arirang is well-known Arirang from the Gangwon province, so it shares certain features of Dongbu minyo (folksong), including the Menaritori. Jeongseon Arirang of Ok-sim Kim is pure and innocent. She has an ingenuous country voice. It is a kind of hope that provides our mental strength. Mental power is as important to our health as a eating right. Jeongseon Arirang sung by Ok-sim Kim is Seoul style of rhythmic pattern and melody. Jeongseon Arirang is designated as the Intangible Cultural Property No. 1 by the Gangwon province in 1971. This article outlines the emotional biography of Jeongseon Arirang of Ok-sim Kim relationship.

• Proceedings of the Korea Contents Association Conference
• /
• 2019.05a
• /
• pp.211-212
• /
• 2019

The objectives of this research are to test the utility of semiparametric geographically weighted regression (SGWR, a spatial analysis method) in the small-scale urban sample, and to understand the geographic patterns of provision and pricing of sharing economy based accommodations in the tourist city. This paper focused on how network distance to heritage site, to casino, residential unit prices and other five attribute categories determine Airbnb price in Macau SAR, China. Findings show that SGWR models outperformed OLS models. Moreover, comparing with heritage sites, casinos are the stronger factors to drive up Airbnb (including hostels) rooms' provision and their prices; and residential unit prices are not related with the Airbnb price in the attraction clusters in Macau. This research showed a little example for the applications of SGWR in the small city, and for the analysis of online marketplace data as new urban study material. Practically, this study provides some scientific evidence for hosts, guests, urban planners, and policymakers' decision making in Macau.

• CELLMED
• /
• v.8 no.4
• /
• pp.25.1-25.2
• /
• 2018

The aim of this article is to suggest that Samulnori will be able to produce better and more lovable language. Samulnori is a good example of the Korean music. Samulnori is originally meaning four-percussion play. Janggu and buk made of leather which were mainly cowskin and dogskin. But jing and kkaengwari made out of brass. Four percussions are an instrument composed of a pattern based on the theory of yin and yang. The principle of Samulnori rhythms are well made up of the relaxation, tension, improvisation, escalating rhythms, and dynamic sound. Samulnori looks like two lovers exchanging sweet words in the natural forest. The push and pull between four instruments like a love quarrel. The author feels that the rhythms of the four instruments are like the whispers and cries of lovers. In conclusion, the silent or passionate rhythm of Samulnori feels like two lovers' tightrope love. The author thinks it creates a rich language of love.

• The Journal of Internal Korean Medicine
• /
• v.41 no.2
• /
• pp.256-266
• /
• 2020

Objectives: This report presents the case of a 21-year-old woman with lower extremity paresthesia in both feet due to polyneuropathy. Methods: The patient was treated using a Korean traditional complex treatment approach that included herbal medication, acupuncture, electroacupuncture, and moxibustion. We evaluated the improvements in the pain symptoms in both feet using the numeric rating scale (NRS); we also assessed for gait disturbance and used Digital Infrared Thermographic Imaging (D.I.T.I.) to evaluate minute changes in body temperature in diseased areas. Results: After administering the Korean traditional complex treatment, we observed a decrease in pain levels in both feet based on the NRS scores. We also observed improvements in gait disturbance and D.I.T.I. Conclusions: This case showed that the use of a Korean traditional complex treatment approach, consisting of herbal medication, acupuncture, electroacupuncture, moxibustion, had a positive effect on decreasing polyneuropathy symptoms.

• CELLMED
• /
• v.8 no.3
• /
• pp.13.1-13.8
• /
• 2018

In the field of osteoporosis, there has been growing interest in anabolic agents that enhance bone formation. The purpose of this study was to examine the effects of NNMBS 246 osteoblastic differentiation with associated signaling pathways. NNMBS 246 markedly increased alkaline phosphatase (ALP) activity and calcium nodule formation. Stimulation with NNMBS 246 not only increased the differentiation markers (ALP, OPN, OCN) level and transcription markers (RUNX2, Osterix) mRNA expression but also upregulated the ECM molecules and OPG mRNA expression. Treatments of NNMBS 246 downregulated MMPs (MMP-1, MMP-2, MMP-9), but RANKL mRNA expression. Furthermore, NNMBS 246 activated osteoblastic differentiation markers and formed calcium nodules in human periodontal ligament cells (hPDLCs) and cementoblast cells. NNMBS 246 induced phosphorylation of MAPKs, Akt, nuclear p65 and IkB-${\alpha}$. BMP-2/Smad and ${\beta}$-catenin signaling pathways were activated by NNMBS 246. Sirtinol (SIRT1 inhibitor) inhibited NNMBS 246-induced osteoblastic differentiation markers mRNA expression. These results suggested that NNMBS 246 has the potential to enhance osteoblastogenesis probably through the activation of BMP/Smad and ${\beta}$-catenin signal pathways, and SIRT1 plays as critical mediator in bone anabolic effect of NNMBS 246.

• The Journal of Internal Korean Medicine
• /
• v.12 no.2
• /
• pp.129-137
• /
• 1991

This study has been carried out to investigate the cause symptom and treatment of wind-coughing ( 風嗽 ) by referring to 38 literatures. The results were obtained as follows; 1. The factors causing wind-coughing ( 風嗽 ) is wind-air. The 1st factors are mistaking of transport lung-air ( 肺氣不宣 ) and cleaning lung (肺失淸肅). 2. The symptom of wind-coughing ( 風嗽 ) is as follows. Bi Saek Sung Jung ( 鼻塞聲重 ), Gu Gun Hu Yang ( 口乾喉痒 ), A Mi Kung I Hae ( 語未竟而咳 ), Maek Bu ( 脈浮 ), Jeang Han Jang Yul ( 憎寒壯熱 ), Ja Han OU Pung ( 自汗惡風 ), Bun Jo ( 煩躁 ), Bi Ryu Chung Chae ( 鼻流淸?), Ya Jung 11 Jyung ( 夜重日輕 ). 3. The treatment-method of wind-coughing ( 風嗽 ) is as follow. Bal San Bul Ga Ha ( 發散 不可下 ), So Pung San Han ( 疏風散寒 ), Chung Yul ( 淸熱 ), Sun Pae Ji Hae ( 宣肺止咳 ). 4. The treatment-herbs of wind-coughing ( 風嗽 ) is as follow. Kwan Dong Hwa San ( 款冬花散 ), Gun Bi Cho San ( 金沸草散 ), Sam Yo Tang ( 三拗湯 ), Ji Hae San ( 止嗽散 ), Hang So San ( 杏蘇散), Sang Kuk Yeam ( 桑菊飮).

• Archives of Pharmacal Research
• /
• v.29 no.12
• /
• pp.1096-1101
• /
• 2006

Armeniacae Semen not only contains amygdalin, but emulsin also, which is an enzyme that hydrolyzes amygdalin. The extraction yield of amygdalin from Armeniacae Semen was low, due to the presence of emulsin, when extracted with water. When Schizandrae Fructus solution was used as the extractant; however, amygdalin was almost completely extracted, regardless of the cutting size, due to the absence of the influence of emulsin. In addition, when the crude powder or small piece forms were used with Schizandrae Fructus solution, on epimerization of the D-amygdalin into neoamygdalin occurred. D-amygdalin and its conversion product, neoamygdalin, were quantitatively analyzed by reverse-phase, high-performance liquid chromatography (HPLC), with an optimized eluent of 10 mM sodium phosphate buffer (pH 2.3), containing 11.5% acetonitrile. The concentration and detector response were linearly correlated over the range 0.05 to 2 mM. The detection limits for both D-amygdalin and neoamygdalin were approximately $5\;{\mu}M$ for the amount injected.

• Journal of Sasang Constitutional Medicine
• /
• v.33 no.4
• /
• pp.43-56
• /
• 2021

Objectives This study was aimed to report a significant improvement of chronic diarrhea patient, diagnosed as 'Taeeum type liver heat-lung dryness pattern' based on Sasang medicine. Methods The patient had treatment with Sasang constitutional medicine. The treatment was executed three times everyday from August 27th to September 3rd and two times everyday from September 3rd to September 16th of 2021. Clinical improvement was evaluated with Bristol stool form scale, the degree of abdominal discomfort and nausea compared to the day of hospitalization and the number of defecations and nocturia per day. Results The symptoms of diarrhea, abdominal discomfort and nausea were improved. The number of night urination was decreased from 3-4 times to once a night. Conclusion After the treatment with Sasang constitutional medicine, diarrhea, abdominal discomfort, nausea and the general condition of the patient also improved.

• Journal of Physiology & Pathology in Korean Medicine
• /
• v.16 no.5
• /
• pp.1025-1034
• /
• 2002

The herbal extract (YMT_02) is a modified herbal extracts from Yukmijihwang-tang (YMJ) to promote memory-enhancing. The YMJ extracts has been widely used as an anti-aging herbal medicine for hundred years in Asian countries. The purpose of this study is to; 1) quantitatively evaluate the memory-enhancing effect of YMT_02 by behavior task, 2) identify candidate genes responsible for enhancing memory by cDNA microarray and 3) assess the anti-oxidant effect of YMT_02 on PC12 cell. Memory retention abilities are addressed by passive avoidance task with Sprague-Dawley (SD) male rat. Before the training session, the rats are subdivided into four groups and administrated with YMT_02, Ginkgo biloba, Soya lecithin and normal saline for 10 days. The retention test was performed. 24 hours after the training session. The retention time of the YMT_02 group was significantly (p<0.05) delayed (～100%), whereas Ginkgo biloba and Soya lecithin treatment delayed 20% and 10% respectively. The hippocampi of YMT_02 and control group were dissected and mANA was further purified. After synthesizing cDNA using oligo-dT primer, the cDNA were applied to Incyte rat GEMTM 2 cDNA microarray. The microarray results show that prealbumin(transthyretin), phosphotidylethanolamine N-methyltransferase, and PEP-19 are expressed abundantly in the YMT_02 treated group. Especially, PEP-19 is a neuron-specific protein, which inhibits apoptotic processes in neuronal cell. On the other hand, transcripts of RAB15, glutamate receptor subunit 2 and CDK108 are abundant in control group. Besides, neuronal genes involved in neuronal death or neurodegeneration such as neuronal-pentraxin and spectrin are abundantly expressed in control group. Additionally, the YMT_02 shows an anti oxidative effect in the PC12 cell. The list of differentially expressed genes may implicate further insight on the action and mechanism behind the memory-enhancing effect of herbal extracts YMT_02, for example, anti-apoptotic, anti-oxidative, and neuroprotective effects.