• The Journal of Internal Korean Medicine
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• v.35 no.4
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• pp.428-438
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• 2014

Objectives: Obesity is an important cause of insulin resistance that leads to obese type 2 diabetes. Recently it has been found that obesity is associated with adipose tissue accumulation which causes systemic inflammation. In this study, we investigated effects of Inula helenium on the inflammation in high fat diet-induced insulin resistance mouse. Methods: Insulin resistance was induced in C57BL/6 male mice (19~21 g) on a 60% fat diet. Mice were divided into 3 groups (n=6) of normal, control and Inula helenium. After 12 weeks, body weight, FBS, oral glucose tolerance test (OGTT), serum level of insulin, epididymal fat pad, liver weight and the gene expression of tumor necrosis factor (TNF)-${\alpha}$, interleukin (IL)-6, interleukin (IL)-10 and cluster of differentiation (CD) 68 were measured. Also, adipose tissue macrophage was analyzed by fluorescence activated cell sorting. Results: Inula helenium significantly reduces oral glucose tolerance levels, insulin serum level and adipose tissue macrophage. Also Inula helenium increased IL-10 gene expression and decreased CD68 gene expression. Conclusions: These results show that Inula helenium has anti-insulin resistance and anti-inflammatory effects on a high fat diet-induced insulin resistance mouse model.

• Journal of Information Technology Services
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• v.15 no.3
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• pp.15-31
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• 2016

Sales Force Automation (SFA) is a strategic information system and one of the components of operational CRM system. SFA supports salespeople's activities such as selection of potential customers, creative value proposition, after-sales services, etc. SFA is increasingly used in many companies because it has the advantages to raise the salespeople's productivity by developing forecasting ability, value proposition ability, after sales service ability etc. Many researches have shown that implementation of SFA leads to the increase of salepeople performance, organizational performance, and quality of customer relationship. However, Some prior studies have discussed on the SFA implementation failure and pointed out that one of important causes of this failure is salespeople's resistance to SFA. Although many researches explain SFA acceptance phenomenon using Technology Acceptance Model (TAM) and Theory of Planned Behavior (TPB), these researches didn't deeply investigate the salespeople's resistance to SFA. Therefore, this study focuses on the factors influencing salespeople's resistance to SFA and the relationships among these factors. This study identified three factors (salespeople's perceived loss of power, perceived loss of autonomy, and perceived time and effort waste) influencing salespeople's resistance to SFA. The hypotheses testing results showed that salespeople's perceived loss of power and perceived time and effort waste significantly increased salespeople's resistance to SFA. And salespeople's perceived loss of power plays a mediating role between perceived loss of autonomy/perceived time and effort waste and salespeople's resistance to SFA. At the end of the paper, theoretical and managerial implications of this study and the limitations and future research directions are discussed.

• Journal of the Society of Naval Architects of Korea
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• v.51 no.6
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• pp.459-479
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• 2014

This paper considers experimental and numerical studies on added resistance in waves. As the numerical methods, three different methods, strip method, Rankine panel method and Cartesian-grid method, are applied. The computational results of vertical motion response and added resistance are compared with the experimental data of Series 60($C_B=0.8$) hull, S175 containership and KVLCC2 hull. To investigate the influence of above-still water hull form, a Rankine panel method is extended to two nonlinear methods: weakly-nonlinear and weak-scatterer approaches. As nonlinear computational models, three ships are considered: original KVLCC2 hull, 'Ax-bow' and 'Leadge-bow' hulls. Two of the three models are modified hull forms of original KVLCC2 hull, aiming the reduction of added resistance. The nonlinear computational results are compared with linear results, and the improvement of computational result is discussed. As experimental approach, a series of towing-tank experiment for ship motions and added resistance on the three models (original KVLCC2 hull, 'Ax-bow' and 'Leadge-bow') are carried out. For the original KVLCC2 hull, uncertainty analysis in the measurement of vertical motion response and added resistance is performed in three waves conditions: ${\lambda}/L=0.5$, 1.1, 2.0. From the experimental results, the effects of hull form on added resistance are discussed.

• Journal of the Korean Society of Environmental Restoration Technology
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• v.9 no.6
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• pp.13-22
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• 2006

The purpose of this study is to propose rational methods in order to maintain vegetation condition and soil environment based on the analysis of tree growth in relation to the soil environment, which is one of the most significant environmental factors on vegetation condition in urban parks and open spaces. The result of the study can be described as below;The soil on every study site had strong acidity. In particular, study sites around industrial district and central business district showed extreme soil acidity. Therefore, soil management system is needed in urban parks and green spaces around those areas. Among Cambium Electric Resistance classified by locations of urban parks and open spaces, one in the costal area was the lowest. The Cambium Electric Resistance in the industrial area was the highest. Therefore, soil condition and locational environment in the industrial area are highly related to the Cambium Electric Resistance. Among the factors, which affect Cambium Electric Resistance in different locations, inorganic content was found to be the main factor in all of the study sites. Inorganic content was an important factor to the Cambium Electric Resistance in study sites located in industrial and central business districts. In the study sites located in costal area, Soil acidity was found to be other important factors that affect Cambium Electric Resistance. To improve the soil acidity, soil buffering ability should be improved from activating microorganisms in the soil by using lime and organic material, Since it takes a long time to make a change in the soil structure, well planed maintenance system is required by mid-term or long-term plans.

• Korean Journal of Environmental Agriculture
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• v.16 no.3
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• pp.212-215
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• 1997

Parent isolates and $first-generation(F_1)$ progenies from single-sporangium of Phytophthora infestans were investigated for the acqusition of metalaxyl and streptomycin sulfate(SM) resistance. The parent isolates, KM10, U6, CDB6 showed resistance to metalaxyl, and F817, DNC303, DN107 to SM. Especially, the average mycelial growth of $F_1$ progenies of F817, CDB6, JD1 was more than 51% than parent isolates on 25ppm metalaxyl added V-8 juice agar, whereas those of KM10, U6, JD1 were extended more than 51% similar on 200ppm SM treatment. They acquired resistance on the basis of the standard in this experiment. There were positive correlations between parent isolates and $F_1$colonies in resistance. The $F_1$ colonies obtained from parent isolates showing above interinediate resistance on metalaxyl amended agar acquired much resistance.

• Fire Science and Engineering
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• v.24 no.2
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• pp.44-51
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• 2010

This study, to develop the technology of the fire resistance design of CFT structure based on fire resistance performance design, was suppose to use as basic data for performance design through a measure of temperature and deformation of the CFT specimen as parameter is the concrete compressive strength and load ratio. In accordance with KS F 2257-1 and 7, 24 MPa and 40 MPa and the load ratio of 0.9, 0.6 and 0.2 were imposed on a square column and as a result of evaluating in accordance with the fire resistance criteria, in case of 24 MPa, the fire resistance performance was improved by 73 minutes when the load ratio was reduced by 0.3. And when it comes to 40 MPa, the fire resistance was 31 minutes and 180 minutes when a load ratio was 0.6 and 0.2, respectively. As a result of evaluating fire resistant performance depending on variation of internal concrete strength, it proved that the higher the strength the lower the fire resistance.

• Journal of The Korean Society of Integrative Medicine
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• v.9 no.3
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• pp.125-134
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• 2021

Purpose : This study applies inspiratory muscle resistance exercise with aerobic exercise to smokers and nonsmokers and then determines whether subjects' breathing functions (FVC, FEV1) are increased and how much effect smoking has on the difference in the increase of breathing functions between the two groups. Methods : For this experiment, 26 male adults were selected and randomly allocated to the smoker group (n=13) and nonsmoker group (n=13). The smokers and nonsmokers performed the inspiratory muscle resistance exercise with aerobic exercise three times a week for four weeks. Regarding the breathing functions, the forced vital capacity (FVC) and forced expiratory volume in one second (FEV1) were measured three times: week 0, week 2, and week 4. The aerobic exercise was performed using a stationary bicycle with 8 difficulty levels. The inspiratory muscle resistance exercise was performed using Power Breathe with 10 resistance levels. Results : The study found that the FVC and FEV1 values of the smoker group decreased slightly after four weeks of inspiratory muscle resistance exercise with aerobic exercise. In other words, the difference was not statistically significant. In contrast, the FVC and FEV1 values of the nonsmoker group increased by a statistically significant amount. In addition, the intergroup comparison of the average increases in FVC and FEV1 values showed statistically significant differences. Conclusion : The results of this study show that when inspiratory muscle resistance exercise with aerobic exercise was performed, the increase in the breathing functions of nonsmokers was higher than that of smokers. This confirms that, within the parameters of the study, smoking had a negative effect on the increase of breathing functions. This suggests that quitting smoking must be considered as an essential factor when applying a breathing physiotherapy or a breathing function improvement program in clinical settings

• International Journal of Vascular Biomedical Engineering
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• v.1 no.2
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• pp.20-29
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• 2003

A new treatment for coronary artery occlusive disease is being developed in which a shunt or conduit is placed directly connecting the left ventricle with the diseased artery at a point distal to the obstruction. To aid in assessing and optimizing its benefit, a computational model of the cardiovascular system was developed and used to explore various design conditions. Simulation results indicate that in complete LAD occlusion, flow can be returned to approximately 65% of normal if the conduit resistance is equal for forward and reverse flow, increasing to 80% in the limit in which backflow resistance is infinite. Increases in flow rate produced by asymmetric flow resistance are considerably enhanced in the case of a partial LAD obstruction since the primary effect of resistance asymmetry is to prevent leakage back into the ventricle("steal") during diastole. Increased arterial compliance has little effect on net flow with a symmetric shunt, but leads to considerable augmentation when the resistance is asymmetric. These results suggest that an LV-LAD conduit will be beneficial when stenosis resistance(Rst) > 27 PRU if resistance is symmetric.

• Journal of the Korea Concrete Institute
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• v.12 no.2
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• pp.43-51
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• 2000

This study is to investigate for the frost resistance of high-flowing concrete using finely ground granulated blast-furnace slag with experimental parameters, such as type of binder, type of superplasticizer and method of curing. The resistance to freezing and thawing of high-flowing concrete by type of binder and superplasticizer is presented differently. Though the frost resistance of high-flowing concrete is satisfactory under standard condition, it is required that high-flowing concrete has entrained air like plain concrete. Because the critical spacing factor, being capacity of frost resistance, of high-flowing concrete is longer that of plain concrete, the frost resistance of high-flowing concrete, using finely ground granulated furnace blast slag, is superior to that of plain concrete.

• Journal of Magnetics
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• v.17 no.4
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• pp.280-284
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• 2012

This paper presents a method for evaluating interior permanent magnet synchronous motor (IPMSM) performance over the entire operation region. Using a d-q axis equivalent circuit model consisting of motor parameters such as the permanent magnetic flux, copper resistance, core loss resistance, and d-q axis inductance, a conventional mathematical model of an IPMSM has been developed. It is well understood that in IPMSMs, magnetic operating conditions cause cross saturation and that the iron loss resistance - upon which core losses depend - changes according to the motor speed; for the sake of convenience, however, d-q axis machine models usually neglect the influence of magnetic cross saturation and assume that the iron loss resistance is constant. This paper proposes an analysis method based on considering a magnetic cross saturation and estimating a core loss resistance that changes with the operating conditions and speed. The proposed method is then verified by means of a comparison between the computed and the experimental results.