• Tuberculosis and Respiratory Diseases
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• 제41권4호
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• pp.429-434
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• 1994

저자들은 폐결핵 치료중 흉통, 발열, 기침 등 폐렴소견과 단순흉부 X 선상 결핵의 악화소견으로 본 병원에 입원한 67세 남자에서 순차적인 단순흉부X선과 기관지 내시경 및 조직생검을 통하여 좌측 주기관지에서 발생한 고등급의 점액표피양 암종을 확인하였으며, 진단후 17개월만에 사망한 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다.

• Tuberculosis and Respiratory Diseases
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• 제52권3호
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• pp.288-293
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• 2002

저자들은 객혈을 주소로 내원하여 선천성 폐동맥 부발육증으로 오인한 32세 여자환자를 폐색전증으로 진단하였고, 항응고제 투여를 통해 호전된 예를 문헌고찰과 함께 보고하는 바이다.

• 대한미생물학회지
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• 제18권1호
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• pp.99-110
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• 1983

저자 등은 결핵으로 인해 생긴 공동을 가진 4명의 남자 환자에 있어서 성공적인 결핵화학요법으로 결핵은 치유되어 객담검사에서 결핵균은 더이상 검출되지 않았으나, 계속되는 각혈로 진균검사를 실시한 결과 Pseudallerscheria boydii(불완전세대 Scedosporium apiospermum)에 의한 진균종(眞菌腫)임이 밝혀졌다. 여러 차례의 객담검사로부터 6개월 또는 2년 이상 계속 동일한 균종이 불리 배양되었고 그리고 그들의 혈청은 P. boydii 배양여액 항원과 immunodiffusion test를 실시한 결과 precipitin bands를 형성하였다. 4환자의 흉부 X-선 사진상에는 뚜렷한 진균종음영을 볼 수 없었다. 2명의 환자 객담에서는 P. boydii와 더불어 Candida albicans와 Aspergillus fumigatus가 계속해서 분리 배양되었고 그리고 그들의 혈청에서 그러한 진균들의 항원에 대한 침강항체를 검충할 수 있었다. 3명의 환자는 폐기능이 진균종 제거수술을 허용하지 않았고 1명의 환자는 수술을 거부하였다.

• Tuberculosis and Respiratory Diseases
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• 제67권5호
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• pp.467-470
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• 2009

A traumatic pulmonary pseudocyst is a rare complication of blunt thoracic trauma. The clinical symptoms and signs are similar to other respiratory diseases, such as pulmonary tuberculosis. Therefore, a trauma history with the resulting radiologic and clinical findings is important for making a diagnosis. A 26-year-old male was admitted to our hospital due to cough for 3 days. The chest x-ray revealed diffuse infiltrations and a cavitary lesion at the left lung. His left chest had hit a tree as a result of motorcycle accident one day before admission. Initially, it was assumed that his symptoms and chest X-ray might be due to a tuberculosis infection. However, bronchoscopy revealed old blood clots at both lungs, particularly in the left lower lobe bronchus. A transbronchial lung biopsy showed alveolar hemorrhage. A traumatic pulmonary pseudocyst was diagnosed from his trauma history and these findings. Computed tomography of the chest performed 4 months later showed regression of the cavitary lesion.

• Journal of Chest Surgery
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• 제50권1호
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• pp.50-53
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• 2017

A mixed infection of Mycobacterium abscessus subsp. abscessus (Mab) and Mycobacterium tuberculosis (MTB) in the lung is an unusual clinical manifestation and has not yet been reported. A 61-year-old woman had been treated for Mab lung disease and concomitant pneumonia, and was diagnosed with pulmonary tuberculosis (PTB). Despite both anti-PTB and anti-Mab therapy, her entire left lung was destroyed and collapsed. She underwent left pneumonectomy and received medical therapy. We were able to successfully treat her mixed infection by pneumonectomy followed by inhaled amikacin therapy. To the best of our knowledge, thus far, this is the first description of a mixed Mab and MTB lung infection.

• Tuberculosis and Respiratory Diseases
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• 제45권4호
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• pp.896-901
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• 1998

Pulmonary arteriovenous malformation(PAVM) is an uncommon congenital anomaly. As pulmonary arteriovenous malformation is a direct communication between the branches of pulmonary artery and vein which originated from the malformation of capillary development, major disturbances in gas exchange can result. This malformation results in the several symptoms such as dyspnea, hemopyssis, cyanosis, and severe neurologic complaints. However, the most of patients are usually asymptomatic. Selective pulmonary angiography is well known the helpful diagnostic method. Recently, therapeutic embolization has been advocated as the treatment of choice for pulmonary arteriovenous malformations. We report a case of multiple pulmonary arteriovenous malformation, which was detected on the simple chest X-ray and successfully treated with coil embolization in a 19-year-old asymptomatic woman.

• Tuberculosis and Respiratory Diseases
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• 제78권4호
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• pp.375-379
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• 2015

A 45-year-old man presented with dyspnea and hemoptysis during exercise. A chest computed tomography (CT) revealed multifocal diffuse patchy ground glass opacity and interlobular septal thickening in both the lungs. Permeability pulmonary edema or pulmonary hemorrhage was suspected. Serologic studies for autoimmune disorders and vasculitis were negative. There was no laboratory evidence of coagulopathy, other hematopoietic disease or infectious disease. Considering correlation with exercise, we diagnosed exercise-induced pulmonary hemorrhage (EIPH) or exercise-induced pulmonary edema (EIPE). The patient was managed with antifibrinolytics, antibiotics, and antitussive agent. After a week, follow-up chest CT revealed completely resolved pulmonary hemorrhage. About 2 months after the first event, he visited again with dyspnea and hemoptysis during running. In the present study, we report a case of recurrent pulmonary hemorrhage after exercise.

• Pediatric Infection and Vaccine
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• 제20권3호
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• pp.190-196
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• 2013

결핵은 다양한 임상양상을 보이는 감염병으로 과거에 비해 많이 감소하였고 소아 결핵도 점차 줄어들고 있으나 여전히 중요한 감염병이다. 소아의 결핵은 성인과는 다른 임상적 특징을 가지며 폐외 결핵의 빈도가 성인보다 높고, 청소년의 결핵은 결핵균 감염에서 실제 질병으로 발전될 위험이 크다. 폐외 결핵 중 장결핵은 증상이 비특이적이고 다양하여 진단이 늦어질 경우 사망률 및 이환율이 높아질 수 있다. 크론병 또는 만성적인 소화기 질환과의 감별이 중요하며, 최근 대장 내시경의 발달로 감별 진단이 용이해지고 있다. 저자들은 6개월간 지속된 설사와 복통, 체중 감소와 간헐적이고 반복적인 $37.5-38^{\circ}C$의 발열로 내원한 12세 여아에게서 대장 내시경 검사를 하여 시행한 생검 조직의 PCR 검사와 조직학적 소견으로 장결핵을 진단하였고, 연이어 촬영한 흉부 방사선 상 활동성 폐결핵으로 진단되어 11개월간의 항결핵제 치료로 완치된 증례를 경험하였다.

• Tuberculosis and Respiratory Diseases
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• 제69권3호
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• pp.163-170
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• 2010

Background: Pulmonary tuberculosis remains a health concern in Korea despite major progress in the development of new strategies for diagnosing and treating tuberculosis. In particular, the diagnosis of newly developed pulmonary tuberculosis is on the rise in elderly persons. The aim of this study was to investigate the clinical, radiographic characteristics, and treatment outcomes of pulmonary tuberculosis in the elderly. Methods: The medical records of 113 young (<65 years old) and 112 elderly (${\geq}65$ years old) pulmonary tuberculosis patients diagnosed at Chungnam National University hospital between January 2007 and December 2008 were reviewed. Results: There was no difference in the prevalence of typical symptoms between the younger and the elderly group. Dypsnea was the only symptom that occurred more frequently in the elderly group (16.8% vs 5.5%, p=0.008). On radiological study, pneumonic infiltration type was more common in the elderly group (28.6% vs 16.8%, p=0.035). Sputum Acid fast bacilli smear positivity rate was similar between the 2 groups. Elderly patients with anti-tuberculosis medication had more frequent adverse drug reactions; however, there was no significant difference between the 2 groups in the number of patients required to stop medication due to an adverse drug reaction. There were more patients lost to follow-up in the elderly group (22/112, 19.6% vs 11/113, 9.7%, p=0.036). Conclusion: The majority of elderly patients did not complete the treatment, resulting in a poorer outcome. Therefore, we need to make an effort to support the continued screening of elderly patients by making this economically feasible.

• Pediatric Infection and Vaccine
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• 제8권2호
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• pp.229-233
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• 2001

저자들은 지속적인 고열과 심한 기침 및 가래, 호흡곤란을 주소로 내원한 15세 남아에서 결핵 치료를 받고 있던 중 홍역에 이환 되어 악화되었고, 투약 중이던 모든 약제에 내성이 나타난 폐결핵을 문헌 고찰과 아울러 보고한다.