• Biomedical Science Letters
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• v.12 no.3
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• pp.241-247
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• 2006

To evaluate an effect of pathological liver damage on the cyclohexane (CH) metabolism, rats were pretreated with 50% carbon tetrachloride $(CCl_4)$ dissolved in olive oil (0.1ml/100g body weight) 10 or 17 times intraperitoneally at intervals of every other day. To these liver damaged animals, CH (a single dose of 1.56g/kg body weight, i.p.) was administered at 48hr after the last injection of $CCl_4$. The CH metabolites; cyclohexanol (CH-ol), cyclohexane-l,2-diol (CH-l,2-diol) and cyclohexane-l,4-diol (CH-l,4-diol) and cyclohexanone (CH-one) were detected in the urine of CH treated rats. After CH treatment, the serum levels of CH-ol and CH-one were remarkably increased at 4 hr and then decreased at 8hr in normal group. Whereas in liver damaged rats, these CH metabolites were higher at 8hr than at 4hr. The excretion rate of CH metabolites trom serum into urine was more decreased in liver damaged animals than normal group, with the levels of excretion rate being lower in $CCl_4$ 17 times injected animals than 10 times injected ones. It was interesting that the urinary concentration of CH metabolites was generally more increased in liver damaged animals than normal ones, and the increasing rate was higher in $CCl_4$ 17 times injected rats than 10 times injected ones. Taken all together, it is assumed that reduced urinary excretion rate of CH metabolites in liver damaged rats might be resulted from deteriorated hepatic and renal blood flow, and an increased urinary excretion amount of CH metabolites in liver damaged rats might be caused by reduced expiration amount of the metabolites due to lung damage.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.14 no.6
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• pp.2588-2595
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• 2013

In a traditional hydraulic elevator, elevator car is descended by down control valve, and the oil hydraulic energy must be lost during the descending stroke. In this paper, the performance characteristics of the hybrid type energy saving unit, is used to save the hydraulic energy which is lost during the descending stroke, for a hydraulic elevator are studied. The energy can be reused as the auxiliary power. The results show that the performance characteristics, such as the pressure, flow rate, output current and voltage, efficiency, and the energy recovery rate of the unit are stable and good as the energy recovery rate is 54%, and the energy saving unit is useful to reuse the saved energy during the descending stroke of elevator car. Also, it was confirmed that the energy saving unit can be deployed on a commercial scale.

• Transactions of the Korean Society of Automotive Engineers
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• v.16 no.5
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• pp.37-43
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• 2008

The durability test of turbo-blower for PEM fuel cell is very important process of BOP development. It is a major barrier to the commercialization of these systems for stationary and transportation power applications. Commercial viability depends on improving the durability of the air supply system to increase the reliability and to reduce the lifetime cost. In this study, turbo-blower supported by oil-free bearing is introduced as the air supply system used by 80kW proton exchange membrane fuel systems. The turbo-blower is a turbo machine which operates at high speed, so air foil bearings suit their purpose as bearing elements. The impeller of blower was adopted mixed type of centrifugal and axial. So, it has several advantages for variable operating condition. The turbo-blower test results show maximum parasitic power levels below 1.67kW with the 30,000 rpm rotating speed, the flow rate of air has maximum 163SCFM(@PR1.1). For proper application of FCV, these have to durability test. This paper describes the experiment for confirming endurance and stability of the turbo-blower for 500 hours.

• Journal of Biosystems Engineering
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• v.26 no.5
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• pp.441-448
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• 2001

Hot air heater with light oil combustion is used as the most common heater for greenhouse heating in the winter season. However, exhaust gas heat discharged to atmosphere through chimney reaches up to 10~20% of total heat capacity of the oil burred. In order to recover the heat of this exhaust gas and to use for greenhouse heating, the heat pipe type exhaust heat recovery system was manufactured and tested in this experiment. The system consisted of a heat exchanger made of heat pipes, ø15.88${\times}$600mm located in the rectangular box of 675(L)${\times}$425(W)${\times}$370(H)mm, an air suction fan and air ducts. The number of heat pipe was 60, calculated considering the heat exchange amount between exhaust gas and air and heat transfer capacity of a heat pipe. The working fluid of heat pipe was acetone because acetone is known for its excellent heat transfer capacity. The system was attached to the exhaust gas path. According to the performance test it could recover 53,809 to 74,613kJ/h depending on the inlet air temperature of 12 to -12˚at air flow rate of 1.100㎥/h. The temperature of the exhaust gas left the heat exchanger dropped to 100$^{\circ}C$ from 270$^{\circ}C$ after the heat exchange between the suction air and the exhaust gas.

• Animal Bioscience
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• v.36 no.7
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• pp.1120-1129
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• 2023

Objective: This study aimed to determine the protective efficacy of Buddha's Temple (BT) extract against tert-butyl hydroperoxide (t-BHP)-induced oxidative stress in Gallus gallus chicken embryo fibroblast cell line (DF-1) and its effects on the cell lipid metabolism. Methods: In this experimental study, Gallus gallus DF-1 fibroblast cells were pretreated with BT 10^-7 for 24 hours, followed by their six-hour exposure to t-BHP (100 μM). Water-soluble tetrazolium salt-8 (WST-8) assays were performed, and the growth curve was computed. The intracellular gene expression changes caused by BT extract were confirmed through quantitative polymerase chain reaction (qPCR). Flow cytometry, oil red O staining experiment, and thin-layer chromatography were performed for the detection of intracellular metabolic mechanism changes. Results: The WST-8 assay results showed that the BT pretreatment of Gallus gallus DF-1 fibroblast cell increased their cell survival rate by 1.08%±0.04%, decreased the reactive oxygen species (ROS) level by 0.93%±0.12% even after exposure to oxidants, and stabilized mitochondrial activity by 1.37%±0.36%. In addition, qPCR results confirmed that the gene expression levels of tumor necrosis factor α (TNFα), TIR domain-containing adapter inducing IFN-beta (TICAM1), and glucose-regulated protein 78 (GRP78) were regulated, which contributed to cell stabilization. Thin-layer chromatography and oil red O analyses showed a clear decrease in the contents of lipid metabolites such as triacylglycerol and free fatty acids. Conclusion: In this study, we confirmed that the examined BT extract exerted selective protective effects on Gallus gallus DF-1 fibroblast cells against cell damage caused by t-BHP, which is a strong oxidative inducer. Furthermore, we established that this extract significantly reduced the intracellular ROS accumulation due to oxidative stress, which contributes to an increase in poultry production and higher incomes.

• Tribology and Lubricants
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• v.40 no.1
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• pp.28-37
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• 2024

This paper presents the development of a squeeze film damper (SFD) test rig and experimental identification of the effects of clearance, damper length, journal eccentricity ratio, excitation amplitude, oil supply pressure, and oil flow rate on the damping coefficients of a test SFD with open ends and a central groove. Test data are compared with predictions from a simple model developed for short SFDs with open ends and a central groove. The test results show a significant decrease in the damping coefficient with increasing clearance and a dramatic increase with damper length, which are in good agreement with the simple model predictions. According to the simple model, the damping coefficient is inversely proportional to the cube of the clearance and directly proportional to the cube of the length. An increase in the journal eccentricity ratio results in a dramatic increase in the damping coefficient by as much as 15 times that of the concentric case, particularly at low excitation frequencies. By contrast, the measured damping coefficient remains almost constant with changes in the excitation amplitude and supply pressure, which are not major factors in the damper design. In general, the test data agree well with the simple model predictions, excluding cases that show increases in the SFD length and journal eccentricity, which indicate significant dependency on the excitation frequency.

• The Journal of Engineering Geology
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• v.29 no.4
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• pp.367-381
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• 2019

We investigate pore pressure conditions and reservoir compaction associated with oil and gas production using 3 different permeability models, which are all based on one-dimensional radial flow diffusion model, but differ in considering permeability evolution during production. Model 1 assumes the most simplistic constant and invariable permeability regardless of production; Model 2 considers permeability reduction associated with reservoir compaction only due to pore pressure drawdown during production; Model 3 also considers permeability reduction but due to the effects of both pore pressure drawdown and coupled pore pressure-stress process. We first derive a unified stress-permeability relation that can be used for various sandstones. We then apply this equation to calculate pore pressure and permeability changes in the reservoir due to fluid extraction using the three permeability models. All the three models yield pore pressure profiles in the form of pressure funnel with different amounts of drawdown. Model 1, assuming constant permeability, obviously predicts the least amount of drawdown with pore pressure condition highest among the three models investigated. Model 2 estimates the largest amount of drawdown and lowest pore pressure condition. Model 3 shows slightly higher pore pressure condition than Model 2 because stress-pore pressure coupling process reduces the effective stress increase due to pore pressure depletion. We compare field data of production rate with the results of the three models. While models 1 and 2 respectively overestimates and underestimates the production rate, Model 3 estimates the field data fairly well. Our result affirms that coupling process between stress and pore pressure occurs during production, and that it is important to incorporate the coupling process in the permeability modeling, especially for tight reservoir having low permeability.

• Asian-Australasian Journal of Animal Sciences
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• v.32 no.11
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• pp.1789-1800
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• 2019

Objective: Although alveolar macrophages play a key role in the respiratory immunity of livestock, studies on the mechanism of differentiation and survival of alveolar macrophages are lacking. Therefore, we undertook to investigate changes in the lipid metabolism and survival rate, using 3D4/31 macrophages and Dudleya brittonii which has been used as a traditional asthma treatment. Methods: 3D4/31 macrophages were used as the in vitro porcine alveolar macrophages model. The cells were activated by exposure to phorbol 12-myristate 13-acetate (PMA). Dudleya brittonii extraction was performed with distilled water. For evaluating the cell survival rate, we performed the water-soluble tetrazolium salt cell viability assay and growth curve analysis. To confirm cell death, cell cycle and intracellular reactive oxygen species (ROS) levels were measured using flow cytometric analysis by applying fluorescence dye dichlorofluorescein diacetate and propidium iodide. Furthermore, we also evaluated cellular lipid accumulation with oil red O staining, and fatty acid synthesis related genes expression levels using quantitative polymerase chain reaction (qPCR) with SYBR green dye. Glycolysis, fatty acid oxidation, and tricarboxylic acid (TCA) cycle related gene expression levels were measured using qPCR after exposure to Dudleya brittonii extract (DB) for 12 h. Results: The ROS production and cell death were induced by PMA treatment, and exposure to DB reduced the PMA induced downregulation of cell survival. The PMA and DB treatments upregulated the lipid accumulation, with corresponding increase in the acetyl-CoA carboxylase alpha, fatty acid synthase mRNA expressions. DB-PMA co-treatment reduced the glycolysis genes expression, but increased the expressions of fatty acid oxidation and TCA cycle genes. Conclusion: This study provides new insights and directions for further research relating to the immunity of porcine respiratory system, by employing a model based on alveolar macrophages and natural materials.

• 한국신재생에너지학회:학술대회논문집
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• 2010.11a
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• pp.103.1-103.1
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• 2010

Recently domestic wood pellet boilers are installed in rural and forestry houses. The fuel price per lower heating value of wood pellet is about 20 % lower than that of heating oil on July 2010. In spite of lower price of wood pellet, a few user of wood pellet boiler complain expensive fuel cost. One of this reason is inaccurate or improper air-fuel ratio setting of wood pellet boiler. O2 concentration of flue gas of domestic wood pellet boiler is about 9.7 % and there are few domestic wood pellet boiler which can control air-fuel ratio automatically. We tested a domestic wood pellet boiler in changing boiler thermal output and air-fuel ratio. The nominal boiler thermal output is 25 kW (21 500 kcal/h). We measured thermal efficiency and flue gas concentrations such as CO and NOx at each boiler thermal load with various air-fuel ratio. The results show that if air flow rate is the same as full load and part load, thermal efficiency of part load of 40 % drops about 7.7 %p compared to boiler full load case.

• The Transactions of the Korean Institute of Power Electronics
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• v.11 no.1
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• pp.1-6
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• 2006

This paper proposes an SRM drive system to improve the drive efficiency of the hydraulic system. From the maximum hydraulic pressure and flow rate required by the hydraulic system, a proper SRM is designed and tested. The proposed SRM drive system controls oil pressure of the hydraulic system as well as motor speed. A 2.2[kW], 12/8-pole SR motor and digital controller based DSP are designed and tested for hydraulic pump system. The test results show that the system has some good features such as high efficiency and rapid response characteristics.