• International Journal of Air-Conditioning and Refrigeration
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• 제13권4호
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• pp.167-174
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• 2005

The evaporation heat transfer coefficient of $CO_2$ (R-744) in a horizontal tube was investigated experimentally. The experiments were conducted without oil in a closed refrigerant loop which was driven by a magnetic gear pump. The main components of the refrigerant loop are a receiver, a variable-speed pump, a mass flow meter, a pre-heater and evaporator (test section). The test section consists of a smooth horizontal stainless steel tube of 7.75 mm inner diameter. The experiments were conducted at mass flux of 200 to $500kg/m^2s$, saturation temperature of $-5^{\circ}C\;to\;5^{\circ}C$, and heat flux of 10 to $40kW/m^2$. The test results showed the evaporation heat transfer of $CO_2$ has greater effect on nucleate boiling than convective boiling. The evaporation heat transfer coefficient of $CO_2$ is highly dependent on the vapor quality, heat flux and saturation temperature. The evaporation heat transfer coefficient of $CO_2$ is very larger than that of R-22 and R-134a. In comparison with test results and existing correlations, the best fit of the present experimental data is obtained with the correlation of Jung et al. But the existing correlations failed to predict the evaporation heat transfer coefficient of $CO_2$. Therefore, it is necessary to develop reliable and accurate predictions determining the evaporation heat transfer coefficient of $CO_2$ in a horizontal tube.

• 한국포장학회지
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• 제24권3호
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• pp.113-120
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• 2018

The one-way gas valve developed in this study was designed to prevent the breakage of packages from increased internal pressure, which is a problem in packaged Kimchi, and simultaneously reduce the outflow of the offodor release. The effect of the one-way gas valve on the headspace atmospheric compositions was investigated in the packaging system. The changes of atmospheric compositions and quality factors of Kimchi, such as $CO_2$ accumulation, pH, titratable acidity, and salinity, were measured during a 4-week storage period at $4^{\circ}C$. The Kimchi package with the one-way gas valve dramatically reduced pressure build-up in the pouch by allowing the controlled flow of gas to the atmosphere. In addition, the package design allows the possibility of controlling the gas generated from Kimchi by adjusting the viscosity of the open pressure control oil. The one-way gas valve did not affect the sensory characteristics of Kimchi products during the storage period. Furthermore, the deodorizing capability of the activated carbon contained in the one-way gas valve effectively reduced the off-odor of Kimchi products released along with carbon dioxide. The novel one-way gas valve is considered to be an active packaging system that can solve major problems of expansion and off-odor leakage in the packaging of Kimchi.

• 대한한의학회지
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• 제40권2호
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• pp.51-62
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• 2019

Objectives: This study was designed to evaluate the macrophages polarization of traditional Korean medicine on cardiac pain about Geum-Gwe-Yo-Ryak's two prescriptions including Kwaruhaebaekbanha-tang (KHB) and Kwaruhaebaekpaekju-tang (KHP). Materials and methods: Flow cytometry analysis was used to measure the changes in the ratio of M1 type and M2 type macrophages. Protein expression of nuclear factor-like 2 (Nrf2), heme oxygenase-1 (HO-1), inducible nitric oxide synthase (iNOS), and cyclooxygenase-2 (COX-2) were measured by Western Blot, and ABCA1 and SR-B1 were detected by real time PCR (RT-PCR). Intracellular lipid accumulation was measured by Oil Red O staining (ORO staining). Results: KHB and KHP increase anti-oxidative activity related protein levels including Nrf2 and HO-1. Furthermore, KHB and KHP inhibit lipid accumulation on intracellular levels through induction of ATP binding receptor cassette subfamily A member 1 (ABCA1) and scavenging receptor class B member 1 (SR-B1), respectively. Finally, KHB and KHP also blocked pro-inflammatory mediators including tumor necrosis factor-alpha ($TNF{\alpha}$) and interleukin-6 (IL-6), iNOS and COX-2 expression. Conclusion: This study suggests that KHB and KHP potently regulate the M1/M2 macrophage polarization.

• 대한조선학회논문집
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• 제56권4호
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• pp.343-351
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• 2019

Green water impact may sometimes cause some structure damages on ship's bow deck. Prediction of proper design pressure against the green water impact is an essential task to prevent the possible damages on bow deck. This paper presents a computational method of the bow deck's design pressure against the green water impact. Large heave and pitch motions of ship are calculated by the time domain nonlinear strip method. Green water flow and pressure on bow deck are simulated by the predictor-corrector second kind upstream finite difference method. This green water simulation method is based on the shallow water wave equations expanded for moving bottom conditions. For various kind of ships such as container ship, VLCC, oil tanker and bulk carrier, the green water design pressures on bow deck are computed and discussed. Also, the obtained results of design pressure on bow deck are compared with those of the classification society rules and discussed.

• 한국물환경학회지
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• 제27권4호
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• pp.461-466
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• 2011

The feasibility of utilizing food waste leachate as an external carbon source was tested to enhance biological nutrient removal from an industrial wastewater with an average flow rate of $164,800m^3/d$ and a low carbon/nitrogen ratio of 2.8. A considerable improvement in the removal of nitrogen and phosphorus was observed when a certain amount of the leachate, ranging from 70 to $142m^3/d$, was supplemented to the biological industrial wastewater treatment process. The addition of the leachate led to an increase in the BOD/N ratio (4.5) and the removal efficiency of nutritents from 29.7% to 71.7% for nitrogen and from 34.8% to 65.6% for phosphorus. However, an excessive dose of the leachate that significantly exceeded $120m^3/d$ caused serious operational problems, like oil-layer formation in the grit chamber and scum layer in the primary clarifier. Thus, an supplement of food waste leachate at a dose acceptable to an existing facilities can be a practical and effective means to enhance the nutrient removal from industrial wastewater and to dispose of the food waste leachate.

• Design & Manufacturing
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• 제16권1호
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• pp.55-61
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• 2022

As meters become digital and smart, energy data such as electricity, gas, heat, and water can be accurately and efficiently measured with a smart meter, providing consumers with data on energy used, so that real-time demand response and energy management services can be utilized. Although it is developing from a simple metering system to a smart metering industry to create a high value-added industry fused with ICT, illegal counterfeiting of electronic meters is causing problems in intelligent crimes such as manipulation and hacking of SW. The meter not only allows forgery of the meter data through arbitrary manipulation of the SW, but also leaves a fatal error in the metering performance, so that the OIML requires the validation of the SW from the authorized institution. In order to solve this problem, a quantitative confirmation device was developed in order to eradicate the act of cheating the fuel oil quantity through encoder pulse operation and program modulation, etc. In order to prevent the act of deceiving the lubricator, a device capable of checking pulse forgery was developed, manufactured, and verified. In addition, the performance of the device was verified by conducting an experiment on the meter being used in the actual field. It is judged that the developed quantitative confirmation device can be applied to other flow meters other than lubricators, and in this case, accurate measurement can be induced.

• Nutrition Research and Practice
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• 제18권4호
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• pp.479-497
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• 2024

BACKGROUND/OBJECTIVES: Activating brown adipose tissue (BAT) and browning of white adipose tissue (WAT) can protect against obesity and obesity-related metabolic conditions. Cryptotanshinone (CT) regulates lipid metabolism and significantly ameliorates insulin resistance. Adenosine-5'-monophosphate (AMP)-activated protein kinase (AMPK), a receptor for cellular energy metabolism, is believed to regulate brown fat activity in humans. MATERIALS/METHODS: The in vivo study included high-fat-fed obese mice administered orally 200/400 mg/kg/d CT. They were evaluated through weight measurement, the intraperitoneal glucose tolerance test (IPGTT), intraperitoneal insulin tolerance test (IPITT), cold stimulation test, serum lipid (total cholesterol, triglycerides, and low-density lipoprotein) measurement, hematoxylin and eosin staining, and immunohistochemistry. Furthermore, the in vitro study investigated primary adipose mesenchymal stem cells (MSCs) with incubation of CT and AMPK agonists (acadesine)/inhibitor (Compound C). Cells were evaluated using Oil Red O staining, Alizarin red staining, flow cytometry, and immunofluorescence staining to identify and observe the osteogenic versus adipogenic differentiation. Quantitative real-time polymerase chain reaction and the Western blot were used to observe related gene expression. RESULTS: In the diet-induced obesity mouse model mice CT suppressed body weight, food intake, glucose levels in the IPGTT and IPTT, serum lipids, the volume of adipose tissue, and increased thermogenesis, uncoupling protein 1, and the AMPK pathway expression. In the in vitro study, CT prevented the formation of lipid droplets from MSCs while activating brown genes and the AMPK pathway. AMPK activator enhanced CT's effects, while the AMPK inhibitor reversed the effects of CT. CONCLUSION: CT promotes adipose tissue browning to increase body thermogenesis and reduce obesity by activating the AMPK pathway. This study provides an experimental foundation for the use of CT in obesity treatment.

• Asian-Australasian Journal of Animal Sciences
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• 제20권9호
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• pp.1407-1416
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• 2007

Ten, first lactation, 87.5%HF dairy cattle were used to investigate effects of long-term administration of recombinant bovine somatotropin (rbST) on nutrient uptake by the mammary gland at different stages of lactation. Measurements of arterial plasma concentrations and arterial-venous differences of metabolites across the mammary gland were performed in combination with measurment of mammary blood flow to estimate the mammary uptake. Animals in experimental groups were injected subcutaneously every 14 days from day 60 of lactation with a prolonged-release formulation of 500 mg of rbST (POSILAC, Monsanto, USA) or with sterile sesame oil without rbST in the control group. During early lactation, the milk yield of rbST-treated animals was higher than that of the control animals (p<0.05). The peak milk yield in both groups of animals declined from the early period of lactation with progression to mid- and late-lactation. No significant changes were observed in the concentration of milk lactose, while the concentrations of milk protein significantly increased as lactation advanced to mid- and late-lactation in both groups. Milk fat concentrations were significantly higher in rbST-treated animals than in control animals, particularly in early lactation (p<0.05). Mammary blood flow (MBF) markedly increased during rbST administration and was maintained at a high level throughout lactation. The mean arterial plasma concentrations for glucose and acetate of rbST-treated animals were unchanged. The net mammary glucose uptake of rbST-treated animals increased approximately 20% during early lactation, while it significantly decreased (p<0.05), including the arteriovenous differences (A-V differences) and extraction ratio across the mammary gland, as lactation advanced to mid- and late-lactation. A-V differences, mammary extraction and mammary uptake for acetate increased during rbST administration and were significantly higher (p<0.05) than in the control animals in early and mid-lactation. Mean arterial plasma concentrations for ${\beta}$-hydroxybutyrate and free glycerol were unchanged throughout the experimental periods in both groups. A-V differences and extraction ratio of ${\beta}$-hydroxybutyrate across the mammary gland did not alter during rbST administration. Mean arterial plasma concentrations for free fatty acids ($C_{16}$ to $C_{18}$), but not for triacylglycerol, increased in rbST-treated animals and were significantly higher than in control animals during early lactation (p<0.01). These findings suggest that an increase in MBF during rbST administration would not be a major determinant in the mediation of nutrient delivery and uptake by the mammary gland for increased milk production. Local changes in biosynthetic capacity within the mammary gland would be a factor in the utilization of substrates resulting in the rate of decline in milk yield with advancing lactation.

• 한국해양환경ㆍ에너지학회지
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• 제18권4호
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• pp.263-273
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• 2015

전세계 플라스틱 해양쓰레기의 유입량과 현존량을 추정하였다. 한국에서 플라스틱 해양쓰레기의 연간 유입량(72,956톤)은 플라스틱의 연간 소비량(5.2백만톤)의 1.4%로 추정되었다. 유출량이 0이라는 가정과 함께, 이 1.4% 유입률을 1950년부터 2013년까지 전세계 플라스틱 생산량에 적용함으로써, 2013년 전세계 연간 플라스틱 해양쓰레기 유입량은 4.2백만톤이며, 2013년말 현재 플라스틱 해양쓰레기 현존량은 86백만톤으로 추정되었다. 또한 로지스틱 모델에 따라, 석유생산량의 4%가 플라스틱으로 생산될 때 플라스틱 해양쓰레기의 최종 현존량은 199백만톤이 될 것으로 추정되었다. 유입량과 현존량은 전혀 다른 측정단위이기 때문에, 유입 저감 정책의 효과성을 평가할 수 있는 개선된 지표가 필요하다. 또한, 플라스틱 해양쓰레기 오염은 거의 회복불가능하기 때문에, 이를 예방하는 대책의 가치는 훨씬 더 높게 평가되어야 하며, 사전주의의 원칙에 따라 더 강력한 예방 대책이 시행되어야 한다. 본 연구는 제한적인 정보에 근거한 예비 연구에 해당하므로 플라스틱 해양쓰레기의 유입량과 현존량의 경향을 규명하기 위한 추가 연구가 필요하다.

• 한국습지학회지
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• 제9권1호
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• pp.69-78
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• 2007

Constructed wetlands and other aquatic systems have been successfully used for waste and wastewater treatment in either temperate or tropical regions. To treat waste or wastewater in a sustainable manner, the integrated eco-engineering designs are explained in this paper with 2 case studies: (i) a combination of vertical-flow constructed wetland (CW) with plant irrigation systemfor fecal sludge management and (ii) integrated CW units with landscaping at full-scale application for domestic wastewater treatment. The pilot-scale study of fecal sludge management employed 3 vertical-flow CW units, each with a dimension of $5{\times}5{\times}0.65m$ (width ${\times}$ length ${\times}$ media depth) and planted with cattails (Typha augustifolia). At the solid loading rate of 250 kg total solids (TS)/$m^2.yr$ and a 6-day percolate impoundment, the CW system could achieve chemical oxygen demand (COD), TS and total Kjeldahl nitrogen (TKN) removal efficiencies in the range of 80 - 96%. The accumulated sludge layers of about 80 - 90 cm was found at the CW bed surface after operating the CW units for 7 years, but no clogging problem has been observed. The CW percolate was applied to 16 irrigation Sunflower plant (Helianthus annuus) plots, each with a dimension of $4.5{\times}4.5m$ ($width{\times}length$). In the study, the CW percolate were fed to the treatment plots at the application rate of 7.5 mm/day but the percolate was mixed with tap water at different ratio of 20%, 80% and 100%. Based on a 1-year data of 3-crop plantation were experimented, the contents of Zn, Mn and Cu in soil of the experimental plots were found to increase with increasing in CW percolate ratios. The highest plant biomass yield and oil content of 1,000 kg/ha and 35%, respectively, were obtained from the plots fed with 20% or 50% of the CW percolate, whereas no accumulation of heavy metals in the plant tissues (i.e. leaves, stems and flowers) of the sunflower is found. In addition to the pilot-scale and field experiments, a case study of the integrated CW systems for wastewater treatment at Phi Phi Island (a Tsunami-hit area), Krabi province, Thailand is illustrated. The $5,200-m^2$ CW systems on Phi Phi Island are not only for treatment of $400m^3/day$ wastewater from hotels, households or other domestic activities, but also incorporating public consultation in the design processes, resulting in introducing the aesthetic landscaping as well as reusing of the treated effluent for irrigating green areas on the Island.