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A Collecting and Record of Wide Area Cultural Resources : the Case of Asian Cotton Cultural Resources (광역 문화자원의 수집과 기록 : 아시아 목화문화자원을 중심으로)

  • Noh, Shi-Hun
    • The Korean Journal of Archival Studies
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    • no.28
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    • pp.123-153
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    • 2011
  • In Asia, when cotton and cotton fabrics cultivated and produced in India of Southern Asia had spread to the whole Asia area by land and by sea, the Cotton Road and cotton fabric cultural area could be formed. In Korea, the traditional cotton (Gossypium arboreum) brought by Moon Ik-Jeom in 1363 was cultivated and then the Upland cotton (Gossypium hirsutum) brought via Japan could be produced from 1904. Especially, Gwangju/Jeonnam was the most active place in producing traditional cotton, and eventually became the center of cotton cultivation and fabric production after bringing in Upland cotton. In order to collect and record the cotton cultural resources in the broad area, the Cultural Resources Set, classified its component parts should be made first and then the collecting objects should be investigated. The collecting areas are selected based on the spreading paths and the regional significance of cotton. Since its difficulty of collecting the relevant resources from all of the places in Asia, it should be planned to share the resources through exchanges and cooperation among private, institution and organization. The relevant experts from the various fields should participate in the interdisciplinary researches which are necessary for collecting and recording of wide area cultural resources. Considering the collecting limitation of genuine relics, the digital archives should be established and then offered through a web site that everyone can use them freely by remote. It also needs to plan to display on and off-line for users to perceive the similarity, difference and interconnections of the resources with ease.

Neutrophil-to-lymphocyte Ratio as A Predictor of Aspiration Pneumonia in Drug Intoxication Patients (약물중독 환자에서 Neutrophil Lymphocyte Ratio의 흡인성폐렴 발생 예측인자로서의 고찰)

  • Lee, Jeong Beom;Lee, Sun Hwa;Yun, Seong Jong;Ryu, Seokyong;Choi, Seung Woon;Kim, Hye Jin;Kang, Tae Kyung;Oh, Sung Chan;Cho, Suk Jin;Seo, Beom Sok
    • Journal of The Korean Society of Clinical Toxicology
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    • v.16 no.2
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    • pp.61-67
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    • 2018
  • Purpose: To evaluate the association between neutrophil-to-lymphocyte ratio (NLR) and occurrence of aspiration pneumonia in drug intoxication (DI) patients in the emergency department (ED) and to evaluate the relationship between NLR and length of hospital admission/intensive care unit (ICU) admission Methods: A total of 466 patients diagnosed with DI in the ED from January 2016 to December 2017 were included in the analysis. The clinical and laboratory results, including NLR, were evaluated as variables. NLR was calculated as the absolute neutrophil count/absolute lymphocyte count. To evaluate the prognosis of DI, data on the development of aspiration pneumonia were obtained. Also, we evaluated the relationship between NLR and length of hospital admission and between NLR and length of ICU admission. Statistically, multivariate logistic regression analyses, receiver-operating characteristic (ROC) curve analysis, and Pearson's correlation (${\rho}$) were performed. Results: Among the 466 DI patients, 86 (18.5%) developed aspiration pneumonia. Multivariate logistic regression analysis revealed NLR as an independent factor in predicting aspiration pneumonia (odds ratio, 1.7; p=0.001). NLR showed excellent predictive performance for aspiration pneumonia (areas under the ROC curves, 0.815; cut-off value, 3.47; p<0.001) with a sensitivity of 86.0% and a specificity of 72.6%. No correlations between NLR and length of hospital admission (${\rho}=0.195$) and between NLR and length of ICU admission (${\rho}=0.092$) were observed. Conclusion: The NLR is a simple and effective marker for predicting the occurrence of aspiration pneumonia in DI patients. Emergency physicians should be alert for aspiration pneumonia in DI patients with high NLR value (>3.47).

Multi-objective Optimization Model for Tower Crane Layout Planning in Modular Construction (모듈러 건축의 타워크레인 배치계획 수립을 위한 다중 최적화 모델 개발)

  • Yoon, Sungboo;Park, Moonseo;Jung, Minhyuk;Hyun, Hosang;Ahn, Suho
    • Korean Journal of Construction Engineering and Management
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    • v.22 no.1
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    • pp.36-46
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    • 2021
  • With an increasing trend toward high-rise modular construction, the simultaneous use of tower cranes at a modular construction site has recently been observed. Tower crane layout planning (TCLP) has a significant effect on cost, duration, safety and productivity of a project. In a modular construction project, particularly, poor decision about the layout of tower cranes is likely to have negative effects like additional employment of cranes and redesign, which will lead to additional costs and possible delays. It is, therefore, crucial to conduct thorough inspection of field conditions, lifting materials, tower crane capacity to make decisions on the layout of tower cranes. However, several challenges exist in planning for a multi-crane construction site in terms of safety and collaboration, which makes planning with experience and intuition complicated. This paper suggests a multi-objective optimization model for selection of the number of tower cranes, their models and locations, which minimizes cost and conflict. The proposed model contributes to the body of knowledge by showing the feasibility of using multi-objective optimization for TCLP decision-making process with consideration of trade-offs between cost and conflict.

Low Resistance Indium-based Ohmic Contacts to N-face n-GaN for GaN-based Vertical Light Emitting Diodes (GaN계 수직형 발광 다이오드를 위한 N-face n-GaN의 인듐계 저저항 오믹접촉 연구)

  • Kang, Ki Man;Park, Min Joo;Kwak, Joon Seop;Kim, Hyun Soo;Kwon, Kwang Woo;Kim, Young Ho
    • Korean Journal of Metals and Materials
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    • v.48 no.5
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    • pp.456-461
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    • 2010
  • We investigated the In-based ohmic contacts on Nitrogen-face (N-face) n-type GaN, as well as Ga-face n-type GaN, for InGaN-based vertical Light Emitting Diodes (LEDs). For this purpose, we fabricated Circular Transfer Length Method (CTLM) patterns on the N-face n-GaN that were prepared by using a laser-lift off method, as well as on the Ga-face n-GaN that were prepared by using a dry etching method. Then, In/transparent conducting oxide (TCO) and In/TiW schemes were deposited on the CTLM in order for low resistance ohmic contacts to form. The In/TCO scheme on the Ga-face n-GaN showed high specific contact resistance, while the minimum specific contact resistance was only 3${\times}$10$^{-2}$ $\Omega$-cm$^{2}$ after annealing at 300${^{\circ}C}$, which can be attributed to the high sheet resistance of the TCO layer. In contrast, the In/TiW scheme on the Ga-face n-GaN produced low specific contact resistance of 2.1${\times}$10$^{5}$ $\Omega$-cm$^{2}$ after annealing at 500${^{\circ}C}$ for 1 min. In addition, the In/TiW scheme on the N-face n-GaN also resulted in a low specific contact resistance of 2.2${\times}$10$^{-4}$ $\Omega$-cm$^{2}$ after annealing at 300${^{\circ}C}$. These results suggest that both the Ga-face n-GaN and N-face n-GaN.

A Study on the Analysis of the Weak Areas of Taxi Service during Late Night Time (심야시간 대 택시 서비스 취약예상지역 분석 연구)

  • Song, Jaein;Kang, Min Hee;Cho, Yun Ji;Hwang, Kee yeon
    • The Journal of The Korea Institute of Intelligent Transport Systems
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    • v.19 no.6
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    • pp.163-179
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    • 2020
  • With the expansion of platform-based taxi service, mobility and convenience of users are getting better. However, due to profitability problem, marginalized areas in the supply of the service are expected to appear. As such, this study analyzed spatial marginalization of taxi service caused by imbalance in supply and demand during the night-time when public transportation service is suspended. According to hot-spot analysis of taxi, outskirt of a city and residential areas showed high vacancy and greater number of drop-offs compared to the number of pick-ups. On the contrary, they were confirmed low in the center and sub-centers of a city. Centrality analysis also showed a similar pattern with hot-spot analysis. Due to this, drivers may refuse to pick up a customer bound for an area with lower out-degree centrality compared to in-degree centrality as it might be difficult for the drivers to pick up another customer after dropping off the current customer. Thus, customers may need to wait for a taxi for a longer time. For this reason, improvement in spatial marginalization caused by mismatch of supply and demand is required. Also, the outcome of this study is expected to be utilized as a basic data.

Optimization of Extrusion Cooking Conditions for the Preparation of Seasoning from Manila Clam Ruditapes philippinarum (바지락(Ruditapes philippinarum) 조미소재 제조를 위한 Extrusion Cooking 공정의 최적화)

  • Shin, Eui-Cheol;Kwak, Dongyun;Ahn, Soo-Young;Kwon, Sangoh;Choi, Yunjin;Kim, Dongmin;Choi, Gibeom;Boo, Chang-Guk;Kim, Seon-Bong;Kim, Jin-Soo;Lee, Jung Suck;Cho, Suengmok
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.53 no.6
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    • pp.823-833
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    • 2020
  • The Manila clam Ruditapes philippinarum, is an important marine bivalve that is widely distributed along the west and north coasts of South Korea. It has been used in a variety of Korean foods owing to its superior umami taste. In the present study, we developed a flavoring with an excellent sensory preference from Manila clam using extrusion cooking processing. Optimization of extrusion cooking conditions was performed using response surface methodology (RSM). Barrel temperature (X1, 140-160℃) and screw speed (X2, 400-560 rpm) of the extruder were chosen as independent variables. The dependent variable was overall acceptance (Y, points). The estimated optimal conditions were as follows: overall acceptance (Y): X1=140℃ and X2=560 rpm. The indicated value of the dependent variable overall acceptance (Y) under the optimal conditions was 8.94 points, which was similar to the experimental value (8.82 points). Overall acceptance of the Manila clam flavoring was related to its umami and Manila clam tastes. The electronic nose and tongue results successfully segregated different clusters of the samples between the lowest and highest sensory scores. The sample with the highest sensory score had higher sourness, umami, and sweetness intensities, and the lowest sensory scored sample showed more off-flavor compounds.

A Study on the Activation Strategy of Underground Shopping Malls: Focusing on Public Underground Shopping Malls in Six Major Cities

  • KIM, Gi Pyoung;LEE, Yong Kyu;LEE, Guen Woo;YOU, Chang Kwon
    • The Journal of Industrial Distribution & Business
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    • v.13 no.6
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    • pp.39-49
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    • 2022
  • Purpose: As part of these efforts, in-depth research is needed on efficient and practical utilization of underground spaces and underground shopping malls. In addition, efforts are being made to find effective alternatives to various problems currently occurring in underground shopping malls, but it is not easy. In addition, the development entity and the maintenance entity are different from each other, and the management is not unified, making it difficult to maintain underground shopping malls. From this point of view, it can be said that it is time to actively and specifically discuss ways to revitalize underground shopping malls. Data and methodology: In the domestic distribution environment, traditional markets and shops are stagnating due to rapid changes in consumption patterns, such as the spread of large companies with advanced distribution techniques such as hypermarkets, shopping malls, and SCM, the rapid increase in Internet and home shopping, and the importance of convenience for young consumers. In order to revitalize underground shopping malls, it is necessary to strengthen the organization and self-rescue efforts of merchants' associations, change consciousness through merchant education, change to specialized markets, find nuclear stores and representative restaurants, and support the hardware sector. Results: The connection of underground shopping malls in each region of the country, where commercial districts are separated from each other, will also play an important role in reviving the function of the city in the future. To do this, it is first necessary to connect underground shopping malls that have been cut off. In other words, connection between connectable underground shopping malls should be promoted. Of course, long-term projects should be promoted step by step, and many consultations should be made on how to connect with the ground for each local government. Conclusion: This is because in the future, the underground space cannot just be a walking place, but another space of the Korean Wave where you can experience satisfying the five senses. K-shopping Hallyu content can be created by creating a characteristic story for each underground shopping mall in the city, permanently this story-oriented event, and creating a safe and elegant environment. If there is a story, so-called "Senomi Shopping" will be possible. A new Korean Wave will be created that can satisfy "the fun of writing, the fun of seeing, and the fun of feeling" at the same time.

Evaluation of Ventilation Performance of a Residential Unit for Different Sampling Points through Actual Field Tests (실증실험을 통한 측정 위치에 따른 주거공간 환기성능 평가)

  • Kwag, Byung Chang;Lee, Soo Man;Kim, Gil Tae;Kim, Jong Yeob
    • Land and Housing Review
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    • v.13 no.3
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    • pp.93-106
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    • 2022
  • Ventilation plays an important role in controlling indoor air quality. Due to the recent spread of infectious diseases such as COVID-19 and with people spending more time indoors, there's been increased attention on the importance of ventilation performance. In many countries, ventilation is regulated by airflow rates and the number of air changes per hour (ACH). However, airflow rates and ACH alone do not provide an accurate account of actual indoor pollutant removal and ventilation uniformity in a space. This study looked into the ventilation performance of an actual residential unit using several sampling points instead of basing it off of airflow and air change rates. Literature review was used to derive relevant influencing factors and the tracer gas dilution method was used for the field test. The study measured air velocity, age of air, and ventilation efficiency at several locations and compared them to the average value at the center of the test space to determine the differences in ventilation performance at the selected measurement points. The study showed that different sampling locations resulted in different ventilation values. Findings of this study will be used to develop an experimental procedure for evaluating indoor ventilation performance of actual residential spaces.

Measurements of mid-frequency transmission loss in shallow waters off the East Sea: Comparison with Rayleigh reflection model and high-frequency bottom loss model (동해 천해환경에서 측정된 중주파수 전달손실 측정: Rayleigh 및 HFBL 모델과의 비교)

  • Lee, Dae Hyeok;Oh, Raegeun;Choi, Jee Woong;Kim, Seongil;Kwon, Hyuckjong
    • The Journal of the Acoustical Society of Korea
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    • v.40 no.4
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    • pp.297-303
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    • 2021
  • When sound waves propagate over long distances in shallow water, measured transmission loss is greater than predicted one using underwater acoustic model with the Rayleigh reflection model due to inhomogeneity of the bottom. Accordingly, the US Navy predicts sound wave propagation by applying the empirical formula-based High Frequency Bottom Loss (HFBL) model. In this study, the measurement and analysis of transmission loss was conducted using mid-frequency (2.3 kHz, 3 kHz) in the shallow water of the East Sea in summer. BELLHOP eigenray tracing output shows that only sound waves with lower grazing angle than the critical angle propagate long distances for several kilometers or more, and the difference between the predicted transmission loss based on the Rayleigh reflection model and the measured transmission loss tend to increase along the propagation range. By comparing the Rayleigh reflection model and the HFBL model at the high grazing angle region, the bottom province, the input value of the HFBL model, is estimated and BELLHOP transmission loss with HFBL model is compared to measured transmission loss. As a result, it agrees well with the measurements of transmission loss.

RUNX1-Survivin Axis Is a Novel Therapeutic Target for Malignant Rhabdoid Tumors

  • Masamitsu, Mikami;Tatsuya, Masuda;Takuya, Kanatani;Mina, Noura;Katsutsugu, Umeda;Hidefumi, Hiramatsu;Hirohito, Kubota;Tomoo, Daifu;Atsushi, Iwai;Etsuko Yamamoto, Hattori;Kana, Furuichi;Saho, Takasaki;Sunao, Tanaka;Yasuzumi, Matsui;Hidemasa, Matsuo;Masahiro, Hirata;Tatsuki R., Kataoka;Tatsutoshi, Nakahata;Yasumichi, Kuwahara;Tomoko, Iehara;Hajime, Hosoi;Yoichi, Imai;Junko, Takita;Hiroshi, Sugiyama;Souichi, Adachi;Yasuhiko, Kamikubo
    • Molecules and Cells
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    • v.45 no.12
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    • pp.886-895
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    • 2022
  • Malignant rhabdoid tumor (MRT) is a highly aggressive pediatric malignancy with no effective therapy. Therefore, it is necessary to identify a target for the development of novel molecule-targeting therapeutic agents. In this study, we report the importance of the runt-related transcription factor 1 (RUNX1) and RUNX1-Baculoviral IAP (inhibitor of apoptosis) Repeat-Containing 5 (BIRC5/survivin) axis in the proliferation of MRT cells, as it can be used as an ideal target for anti-tumor strategies. The mechanism of this reaction can be explained by the interaction of RUNX1 with the RUNX1-binding DNA sequence located in the survivin promoter and its positive regulation. Specific knockdown of RUNX1 led to decreased expression of survivin, which subsequently suppressed the proliferation of MRT cells in vitro and in vivo. We also found that our novel RUNX inhibitor, Chb-M, which switches off RUNX1 using alkylating agent-conjugated pyrrole-imidazole polyamides designed to specifically bind to consensus RUNX-binding sequences (5'-TGTGGT-3'), inhibited survivin expression in vivo. Taken together, we identified a novel interaction between RUNX1 and survivin in MRT. Therefore the negative regulation of RUNX1 activity may be a novel strategy for MRT treatment.