• Korean Journal of Veterinary Pathology
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• v.5 no.2
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• pp.49-56
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• 2001

Ocular lesions induced in 40 specific-pathogen-free Marek's disease (MD) resistant chicks by inoculation at 1 day of age with very virulent strain of Marek's disease virus (WV) were pathologically examined. Grossly,24/40 (60%) chicks had white gel-like materials in the vitreous body, whereas thickening and discoloration of iris (gray eye) were not observed. Microscopically, characteristic ocular MD lesions were observed in choroid (27/40), ciliary (30/40) and iris (23/40) in which small focal inflammatory to diffuse neoplastic Iymphoid cells were infiltrated. Five out of 40 MDV-inoculated birds revealed necrotizing Iymphomas in choroid. These lesions consisted of necrotic and degenerating Iymphoblasts accompanied by intranuclear inclusion body. There was retinal atrophy and necrosis with inclusion body detected in necrotic ganglion, inner or outer nuclear and infiltrated Iymphoblast cells. Conjunctiva showed lymphoid cell infiltration in 29/40 chicks inoculated with MDV, Vitreous body exhibited mild to severe exudation of eosinophilic proteinaceous material in 24/40 chicks. These lesions were associated with Iymphoid cell infutration, edema and fibrosis of choroid. Pecten (7/40) and optic nerve (13/40) were infiltrated usually mildly with Iymphoid cells. From these results, very virulent strain, Md/5 of MDV caused high incidence of ocular lesions in MD resistant chicks. In addition, Md/5 induced exudation of proteinaceous material into the vitreous body and fibrosis of choroid. Necrotizing ocular Iymphoma lesions in choroid is the first report in the MD literature.

• Herbal Formula Science
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• v.27 no.4
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• pp.285-297
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• 2019

Objectives : The purpose of this study is to analyze effectiveness of herbal medicine treatment on Dry Eye Syndrome. Methods : We analyze medical records of 114 patients who visited Indara oriental medical clinic for dry eye syndrome. Patients were treated with acupuncture and Inmok-tang, and the ocular surface disease index was evaluated before and after treatment. Results : Analysis of 114 medical records showed a significant decrease in the pre-treatment and post-treatment ocular surface disease index, and a statistically significant positive correlation between the duration of Inmok-tang administration and the change in the ocular surface disease index. Conclusions : Herbal medicine treatment with Inmok-tang reduces the Ocular Surface Disease Index, an indicator of subjective symptoms of dry eye syndrome.

• Journal of Acupuncture Research
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• v.29 no.5
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• pp.39-50
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• 2012

Objectives : The purpose of this study was to identify the effects of self-acupressure on the visual health of college students. Methods : A nonequivalent control group pretest-posttest design was used. Participants were determined by OSDI(ocular surface disease index) and the Schirmer test, they were assigned to an experimental group of 22 and control group of 22. The experimental group participated in self-acupressure, which were practiced 2 times a day, 5 days a week for 4 weeks. Results : Scores of ocular surface disease index, Schirmer test and ocular fatigue were significantly better in the experimental group after the intervention compared to the control group. Conclusions : The result indicate that self-acupressure is an effective nursing intervention for improving the dry eye syndrome and decreasing ocular fatigue in college students.

• Journal of Oriental Neuropsychiatry
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• v.23 no.2
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• pp.59-66
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• 2012

Objectives : The purpose of this report was to examine the relation between ocular fatigue and dry eye symptoms in patients with ocular fatigue. Methods : 115 patients with ocular fatigue disease were included in this analyses. The study examination included a symptom interview that assessed stiff sense, foreign body sense, pain, soreness, redness, etc. and ocular fatigue. Results : The survey showed in subjective ocular fatigue in all subjects. All patients(115) reported symptoms of ocular fatigue and 25.2% (29/115) were diagnosed as having dry eye with symptoms. Conclusions : These findings suggest that there is a strong between ocular fatigue and dry eye.

• Journal of Korean Ophthalmic Optics Society
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• v.19 no.3
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• pp.403-406
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• 2014

Purpose: In this study, we studied ocular disease by age in Ulsan. Methods: We checked medical record of 300 patients who visited eye clinic in Ulsan. Results: The main ocular disease on the age of 10 was keratitis, that of 20 was dry eye syndrome & keratitis, that of 30 was chalazion & conjunctivitis, that of 40~50 was conjunctivitis, that of 60 was conjunctivitis & cataract. Conclusions: The main cause of ocular disease of 10~20's are unsuitable wear of contact lenses & long-time use of smart phone as well as computer. That of 30~50's are allergic conjunctivitis and chemical material reaction as well as other several factors. Especially, attack rate of conjunctivitis of 30~50's is higher than city because of industrial area (Ulsan). The main cause of ocular disease in 50~60's is a kind of senility. Therefore, based on the results of this study, it could be used the basic data of education on ocular disease prevention in Ulsan.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.19 no.3 s.31
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• pp.193-200
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• 2006

Ocular injury is one of the commonest causes of eye diseases, but its patterns and incidences are variable according to the environment. Blunt Ocular Trauma is one of causes of ocular injury. Visual disturbance by Blunt Ocular Trauma is rarely reported and we do not know the exact convalescence and healing method of that. We treated a patient suffered from visual disturbance by blunt ocular trauma with herbal medicine, acupuncture, cupping treatment. We diagnosed as Blood stasis and noxious water disease. We report a case of visual disturbance by blunt ocular trauma after treatments, we observed the improvement. Based on this study, it is considered that oriental medical treatment can be applied to the management of visual disturbance.

• Parasites, Hosts and Diseases
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• v.51 no.4
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• pp.393-400
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• 2013

Ocular toxoplasmosis is a disease caused by the infection with Toxoplasma gondii through congenital or acquired routes. Once the parasite reaches the retina, it proliferates within host cells followed by rupture of the host cells and invasion into neighboring cells to make primary lesions. Sometimes the restricted parasite by the host immunity in the first scar is activated to infect another lesion nearby the scar. Blurred vision is the main complaint of ocular toxoplasmic patients and can be diagnosed by detection of antibodies or parasite DNA. Ocular toxoplasmosis needs therapy with several combinations of drugs to eliminate the parasite and accompanying inflammation; if not treated it sometimes leads to loss of vision. We describe here clinical features and currently available chemotherapy of ocular toxoplasmosis.

• Parasites, Hosts and Diseases
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• v.51 no.6
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• pp.613-619
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• 2013

Angiostrongyliasis, caused by Angiostrongylus cantonensis infection, is a food-borne parasitic disease. Its larvae evoke eosinophilic inflammation in the central nervous system, but can also cause pathological changes in the eyes. Among ocular angiostrongyliasis cases, the incidence of optic neuritis is low and only few sporadic reports exist. Some patients with optic neuritis developed obvious hypopsia or even vision loss, which would seriously influence the quality of life of patients. Prompt treatment of optic neuritis caused by A. cantonensis is the key factor for minimizing the incidence of serious complications of this disease. In this review, we first provide a comprehensive overview of ocular angiostrongyliasis, and then focus on the clinical features of optic neuritis caused by A. cantonensis.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.30 no.6C
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• pp.585-592
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• 2005

One of the most important things in the researches on diseases is to attach more importance to prevention of a disease and preservation of health than to treatment of a disease, also to foods rather than to medicines. In this context, the most significant concern in examining a patient is to find the presence of disease, and, if any, to diaguose the type of disease, after which a pharmacotherapy is followed. In this paper, various diagnosis methods of Oriental medicines are discussed. And ocular inspection, the most important method among the 4 disease diagnoses of Oriental medicines, is studied. Observing a person's shape and color has been the major method for ocular inspection, which usually has been dependent upon doctor's intuition as of these days. We are developing an automatic system which provides objective basic data for ocular inspection. As the first stage, we applied the signal processing techniques to automatic feature extraction of faces for ocular inspection. Firstly, facial regions are extracted from the point of frontal view, which was followed by extraction of their features. The experiment applied to 20 persons showed that frontal face regions are perfectly extracted, as well as their features, such as eyes, eyebrows, noses and mouths. Future work will seek to address the issues of morphological operation for a few unfinished extraction results, such as combined hair and eyebrows.

• Journal of Acupuncture Research
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• v.29 no.4
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• pp.55-69
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• 2012

Objectives : The aim of this study was to compare the effects of 12 acupuncture treatments versus 24 acupuncture treatments for patients with dry eye syndrome. Methods : We have assessed the symptom score, number of dry eye symptoms, and ocular surface disease index(OSDI) scores before and after the acupuncture treatments. The group A received 12 acupuncture treatments, and the group B received 24 acupuncture treatments. To evaluate the efficacy of acupuncture treatments the before and after scores of both groups were compared. Results : After treatment, symptom score, number of dry eye symptoms, and ocular surface disease index(OSDI) were significantly decreased in each group (p<0.001). The symptom score has shown a greater decrease in group B than group A, but no significant differences were seen in the numbers of existing symptoms and ocular surface disease index(OSDI) scores between the two groups. Conclusions : Acupuncture is an effective way to relieve the symptoms of dry eye syndrome. The more number of acupuncture treatments may be correlated with better outcomes in the means of symptom score.