• Asian Pacific Journal of Cancer Prevention
• /
• v.15 no.17
• /
• pp.7149-7152
• /
• 2014

A large number of epidemiological studies have demonstrated that obesity is a risk factor for several human cancers. Several animal studies using rodents with diet-induced or genetic obesity have also demonstrated that obesity can promote tumor development. However, the effects of obesity on the early stages of carcinogenesis, and especially on the spontaneous occurrence of somatic gene mutations, remain unclear. To investigate the effects of obesity on the rate of spontaneous gene mutations, we performed reporter gene mutation assays in liver, kidney, and colon, organs in which obesity appears to be associated with cancer development on the basis of epidemiological or animal studies, in mice with high fat diet (HFD)-induced obesity. Six-week-old male and female C57BL/6 gpt delta mice were fed HFD or standard diet (STD) for 13 or 26 weeks. At the end of the experiments, reporter gene mutation assays of liver, kidney, and colon were performed. Final body weights and serum leptin levels of male and female mice fed HFD for 13 or 26 weeks were significantly increased compared with corresponding STD-fed groups. Reporter gene mutation assays of liver, kidney, and colon revealed that there were no significant differences in gpt or $Spi^-$ mutant frequencies between STD- and HFD-fed mice in either the 13-week or 26-week groups. These results indicate that HFD treatment and consequent obesity does not appear to influence the spontaneous occurrence of somatic gene mutations.

• The Plant Pathology Journal
• /
• v.34 no.4
• /
• pp.308-315
• /
• 2018

Root-knot nematodes 'Meloidogyne spp' are the most destructive group of plant parasitic nematodes causeing serious losses in vegetables crops and this damages worsened when crops grown under greenhouses conditions. In this sutdy, the distribution and characterization of root-knot nematode species collected from the Souss region of Morocco where vegetables crops intensively cultivated were determined by using both morphological and molecular tools. Out of the 110 samples collected from different greenhouses 91 (81.7%) were found to be infested with root-knot nematodes. Thirty-seven populations of root-knot nematodes were morphologically identified based on perineal patterns as well as molecularlly using species-specific primers. The obtained results indicated that Meloidogyne javanica and M. incognita were identified in 86.4% and 13.5% of the total populations, respectively. The lowest incidence of root-knot nematodes (64%) was found in Toussous, whereas the highest frequencies of 100% and 90% were detected in Taddart and Biogra, respectively. As the majority of the samples have been infested with Meloidogyne species; this indicates that there is an urgent need to provide farmers with a proper control strategy.

• KSII Transactions on Internet and Information Systems (TIIS)
• /
• v.8 no.12
• /
• pp.4467-4488
• /
• 2014

The bibliometric analysis is widely used for understanding research domains, trends, and knowledge structures in a particular field. The analysis has majorly been used in the field of information science, and it is currently applied to other academic fields. This paper describes the analysis of academic literatures for classifying research domains and for suggesting empty research areas in the telecommunications policy. The application software is developed for retrieving Thomson Reuters' Web of Knowledge (WoK) data via web services. It also used for conducting text mining analysis from contents and citations of publications. We used three text mining techniques: the Keyword Extraction Algorithm (KEA) analysis, the co-occurrence analysis, and the citation analysis. Also, R software is used for visualizing the term frequencies and the co-occurrence network among publications. We found that policies related to social communication services, the distribution of telecommunications infrastructures, and more practical and data-driven analysis researches are conducted in a recent decade. The citation analysis results presented that the publications are generally received citations, but most of them did not receive high citations in the telecommunications policy. However, although recent publications did not receive high citations, the productivity of papers in terms of citations was increased in recent ten years compared to the researches before 2004. Also, the distribution methods of infrastructures, and the inequity and gap appeared as topics in important references. We proposed the necessity of new research domains since the analysis results implies that the decrease of political approaches for technical problems is an issue in past researches. Also, insufficient researches on policies for new technologies exist in the field of telecommunications. This research is significant in regard to the first bibliometric analysis with abstracts and citation data in telecommunications as well as the development of software which has functions of web services and text mining techniques. Further research will be conducted with Big Data techniques and more text mining techniques.

• Journal of Microbiology and Biotechnology
• /
• v.26 no.6
• /
• pp.1026-1034
• /
• 2016

In the current study, a total of 135 enterococci strains from different sources were screened for the presence of the enterocin-encoding genes entA, entP, entB, entL50A, and entL50B. The enterocin genes were present at different frequencies, with entA occurring the most frequently, followed by entP and entB; entL50A and L50B were not detected. The occurrence of single enterocin genes was higher than the occurrence of multiple enterocin gene combinations. The 80 isolates that harbor at least one enterocin-encoding gene (denoted "Gene⁺ strains") were screened for antimicrobial activity. A total of 82.5% of the Gene⁺ strains inhibited at least one of the indicator strains, and the isolates harboring multiple enterocin-encoding genes inhibited a larger number of indicator strains than isolates harboring a single gene. The indicator strains that exhibited growth inhibition included Listeria innocua strain CLIP 12612 (ATCC BAA-680), Listeria monocytogenes strain CDC 4555, Enterococcus faecalis ATCC 29212, Staphylococcus aureus ATCC 25923, S. aureus ATCC 29213, S. aureus ATCC 6538, Salmonella enteritidis ATCC 13076, Salmonella typhimurium strain UK-1 (ATCC 68169), and Escherichia coli BAC 49LT ETEC. Inhibition due to either bacteriophage lysis or cytolysin activity was excluded. The growth inhibition of antilisterial Gene⁺ strains was further tested under different culture conditions. Among the culture media formulations, the MRS agar medium supplemented with 2% (w/v) yeast extract was the best solidified medium for enterocin production. Our findings extend the current knowledge of enterocin-producing enterococci, which may have potential applications as biopreservatives in the food industry due to their capability of controlling food spoilage pathogens.

• Korean Journal of Food Science and Technology
• /
• v.9 no.1
• /
• pp.73-80
• /
• 1977

In order to detect the occurrence of aflatoxins in some suspecious Korean foodstuffs, 54 samples of Meju (a naturally inoculated soybean substrate for soy sauce and paste fermentation), 125 samples of Doenjang (a Korean-style fermented soybean paste), both produced at household level, and 31 samples of peanut were collected from 8 major cities of South Korea and subjected to assay by the official method of AOAC. The results were as follows: 1) Frequencies for the occurrence of aflatoxins in Meju, Doenjang and peanut were 7.4%(4/54), 8.8%(11/125) and none (0/31), respectively, in which Meju and Doenjang samples from Daegu and Busan showed the high ratio of the presence. 2) A Doenjang sample from Busan was found to contain the highest content of aflatoxins, of which $B_1,\;B_2,\;G_1\;and\;G_2$ were 66 ppb, 13 ppb, non-detectable and 5 ppb, respectively, while other samples detected were for $G_2$ only. 3) The identity of aflatoxin $B_1$ isolated from the Doenjang sample from Busan was confirmed by thin-layer chromatographic behavior, derivative formation and chicken embryo bioassay.

• Convergence Security Journal
• /
• v.17 no.5
• /
• pp.27-34
• /
• 2017

Network security visualization technique using security alerts provide the administrator with intuitive network security situation by efficiently visualizing a large number of security alerts occurring from the security devices. However, most of these visualization techniques represent events using overlap the timelines of the alerts or Top-N analysis by their frequencies resulting in failing to provide information such as the attack trend, the relationship between attacks, the point of occurrence of attack, and the continuity of the attack. In this paper, we propose an effective visualization technique which intuitively explains the transition of the whole attack and the continuity of individual attacks by arranging the events spirally according to timeline and marking occurrence point and attack type. Furthermore, the relationship between attackers and victims is provided through a single screen view, so that it is possible to comprehensively monitor not only the entire attack situation but also attack type and attack point.

• Atmosphere
• /
• v.32 no.4
• /
• pp.353-365
• /
• 2022

This paper evaluates precipitation forecast skill of Global/Regional Integrated Model system (GRIMs) over South Korea in a boreal winter from December 2013 to February 2014. Three types of precipitation are classified based on development mechanism: 1) convection type (C type), 2) low pressure type (L type), and 3) orographic type (O type), in which their frequencies are 44.4%, 25.0%, and 30.6%, respectively. It appears that the model significantly overestimates precipitation occurrence (0.1 mm d^-1) for all types of winter precipitation. Objective measured skill scores of GRIMs are comparably high for L type and O type. Except for precipitation occurrence, the model shows high predictability for L type precipitation with the most unbiased prediction. It is noted that Equitable Threat Score (ETS) is inappropriate for measuring rare events due to its high dependency on the sample size, as in the case of Critical Success Index as well. The Symmetric Extreme Dependency Score (SEDS) demonstrates less sensitivity on the number of samples. Thus, SEDS is used for the evaluation of prediction skill to supplement the limit of ETS. The evaluation via SEDS shows that the prediction skill score for L type is the highest in the range of 5.0, 10.0 mm d^-1 and the score for O type is the highest in the range of 1.0, 20.0 mm d^-1. C type has the lowest scores in overall range. The difference in precipitation forecast skill by precipitation type can be explained by the spatial distribution and intensity of precipitation in each representative case.

• Journal of Korean Society on Water Environment
• /
• v.40 no.3
• /
• pp.121-129
• /
• 2024

Harmful cyanobacterial blooms (HCBs) are caused by the rapid proliferation of cyanobacteria and are believed to be exacerbated by climate change. However, the extent to which HCBs will be stimulated in the future due to increased temperature remains uncertain. This study aims to predict the future occurrence of cyanobacteria in the Nakdong River, which has the highest incidence of HCBs in South Korea, based on temperature rise scenarios. Representative Concentration Pathways (RCPs) were used as the basis for these scenarios. Data-driven model simulations were conducted, and out of the four machine learning techniques tested (multiple linear regression, support vector regressor, decision tree, and random forest), the random forest model was selected for its relatively high prediction accuracy. The random forest model was used to predict the occurrence of cyanobacteria. The results of boxplot and time-series analyses showed that under the worst-case scenario (RCP8.5 (2100)), where temperature increases significantly, cyanobacterial abundance across all study areas was greatly stimulated. The study also found that the frequencies of HCB occurrences exceeding certain thresholds (100,000 and 1,000,000 cells/mL) increased under both the best-case scenario (RCP2.6 (2050)) and worst-case scenario (RCP8.5 (2100)). These findings suggest that the frequency of HCB occurrences surpassing a certain threshold level can serve as a useful diagnostic indicator of vulnerability to temperature increases caused by climate change. Additionally, this study highlights that water bodies currently susceptible to HCBs are likely to become even more vulnerable with climate change compared to those that are currently less susceptible.

• Korean Journal of Agricultural and Forest Meteorology
• /
• v.13 no.3
• /
• pp.148-156
• /
• 2011

The purpose of this study is to analyze the patterns of forest fire possibly related with Asian dust event and carry out a correlation analysis between forest fire occurrence and existence or not of the Asian dust event during dry seasons i.e. February to May in 2000 to 2008. To study the correlation of forest fire and Asian dust, we surveyed information of Asian dust observations, forest fire statistics, fire danger rating index, weather data such as temperature, relative humidity and wind speed of the day occurring the forest fire. As a consequence of analysis, the regional frequency of Asian dust was the highest in Gyeonggi and Chungbuk divisions. Frequencies of forest fire occurrence by the Asian dust events were the highest in the day before three days of the Asian dust event. The highest frequent regions of forest fire occurrence were district of boundary line between Gyeonggi and Western of Gangwon, Chungbuk and Gyeonbuk inland. The correlation between forest fire and fire danger rating index showed the high correlation with the day before three days and after three days of the Asian dust event. These correlation coefficients were 0.50038 and 0.53978 to 1% significance level. The result of analysis between the frequency of forest fire occurrence and wind speed had a highly negative relationship at all the Asian dust days, the day before and after three days. The correlation coefficients had been -0.58623 to -0.61245 to 1% significance level. Relative humidity showed a little of negative relationship with forest fire occurrence in -0.2568(p ${\leq}$ 0.01) for the Asian dust day and -0.35309(p ${\leq}$ 0.01) for next three days. Moreover, at the day before three days of Asian dust events, it was -0.23701 to 1% significance level. However, the mean temperature did not correlate with frequency of forest fire occurrence by Asian dust events at all.

• Journal of Satellite, Information and Communications
• /
• v.12 no.3
• /
• pp.80-85
• /
• 2017

In this paper, a mircrowave breakdown of X-band circular waveguide cavity filter, which occurred during ground test, was introduced, and electro-magnetic field simulation results to identify a root cause, and the analysis of possibility of its occurrence on orbit operation were presented. Filter modeling for simulation was conducted with a commercial tool (FEST3D), and electric fields inside the filter were monitored at the input of 1 W continuous wave. In our observation, strong electric field intensities were monitored on the tuning screws especially at the input of band-edge frequencies. The threshold power levels for the breakdown were also estimated and compared with the input power levels actually injected to the filter. From this estimation, we could figure out that the power exceeding the breakdown threshold was injected to the filter so that strong electric fields were generated and temperature increased high, and this became a root cause of the electrical short. Our further analysis showed that this kind of microwave breakdown is not likely to occur on orbit operation, and multipactor is expected not to occur at the input of band-edge frequencies. As a measure to prevent the microwave breakdown, we suggested to avoid the injection of band-edge frequencies and inject lower power levels to the filter.