• Title/Summary/Keyword: Objective Indicator

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Effects of Magnetized Medium on In Vitro Maturation of Porcine Cumulus Cell-Oocyte Complexes

  • Kim, Yun-Jung;Lee, Sang-Hee;Jung, Soo-Jung;Park, Choon-Keun
    • Journal of Magnetics
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    • v.19 no.3
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    • pp.241-247
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    • 2014
  • The objective of this study was to study the effect of magnetized water on porcine cumulus cell-oocyte complexes (COCs). Oocytes obtained from female pig were cultured in a medium magnetized at 0, 2000, 4000, and 6000 Gauss (G) for 5 minutes using the neodymium magnet. Subsequently, intracellular hydrogen peroxide ($H_2O_2$) concentration, glutathione (GSH) activity, oocyte membrane integrity, anti-apoptosis factor Bcl-xL expression, and nuclear maturation were analyzed. The intracellular $H_2O_2$ levels in COCs cultured for 44 hours were not significantly different among the variously magnetized samples. However, GSH activity were significantly higher in the magnetized samples compared to the 0 G sample. The Bcl-xL mRNA expression in COCs cultured for 44 hours was higher in the 4000 G sample than other treatment groups. Membrane damage in COCs cultured for 22 and 44 hours was significantly lower in 4000 G group than control group. On the other hand, nuclear stages as maturation indicator significantly increased in 2000, 4000, and 6000 G groups compared to 0 G group. These results indicate that incubation of porcine oocytes and cumulus cells in magnetized medium improves intracellular GSH levels, membrane integrity and nuclear maturation, and inhibits apoptosis in vitro.

Effects of Job Satisfaction, Organizational Support and Risk Perception on Safety Consciousness in Confined Space Workers

  • Kim, Yang Rae;Jeong, Byung Yong;Park, Myoung Hwan
    • Journal of the Ergonomics Society of Korea
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    • v.36 no.3
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    • pp.245-254
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    • 2017
  • Objective: This study aims to investigate the effects of organizational support, risk perception and job satisfaction on safety consciousness in confined space works. Background: Confined space works are rated as hazardous works with high injury frequency and fatalities. But there were few researches for the occupational injury of the confined space workers. Method: Questionnaire survey targeting 236 workers working in confined spaces were carried out to construct the structural equation model on safety consciousness. The participants were all male workers, and they install and maintain or clean facilities mainly in the confined spaces. Results: A structural equation model for safety consciousness was proposed, and validated based on perceived organizational support, risk perception and job satisfaction factors. Perceived 'organizational support' contributed significantly to 'worker's safety consciousness' both directly and indirectly. Also, perceived 'worker's safety consciousness' was also affected by perceived 'job satisfaction' and 'risk perception'. In terms of magnitude of relationships, the direct effect of perceived 'job satisfaction' on 'worker's safety consciousness' was the greatest among the interrelationships among latent factors. Conclusion: Workers' safety consciousness can function as a leading indicator for safety and hazard prevention of workers. Application: The results can be used in developing safety prevention programs for confined space workers.

Evaluation of the Relationship between the Results of Blood Test and Sasang Constitution (사상체질과 혈액검사 결과의 연관성 평가)

  • Jeong, Mi Kyung;Youn, Sang Jun;Jun, Chan Yong;Park, Jong Hyeong;Choi, You Kyung
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.26 no.6
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    • pp.964-969
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    • 2012
  • This study aimed to evaluate the relationship between the results of blood test and Sasang constitution. We performed blood test of 2,387 university students in Health examination. Sasang constitution was diagnosed by using the Questionnaire of Sasang Constitution Class II(QSCC II). All the data were analysed statistically by descriptive statistics, ANOVA and logistic regression analysis. The Taeeumin group showed significantly higher AST, ALT, GGT, LDH, CPK, creatinine, uric acid, total cholesterol, TG, and LDL levels than other groups, while having a lower HDL level. According to logistic regression analysis, Hb, RBC, uric acid, creatinine were effective common factors for classifying each constitution groups. In the results of this study, there were significant differences in the results of blood test between the three constitutions. But the blood test was insufficient as an objective indicator for discriminating Sasang constitutions.

Investigation of Potential Photoreactivation of Pseudomonas aeruginosa after LP or MP UV Irradiation (저압 및 중압 자외선 조사에 의해 불활성화된 Pseudomonas aeruginosa의 광회복능 조사)

  • Mun, Sung-Min;Cho, Min;Yoon, Je-Yong
    • Journal of Korean Society of Water and Wastewater
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    • v.20 no.5
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    • pp.755-761
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    • 2006
  • Recently, there is growing interest in ultraviolet (UV) irradiation as a disinfection technic in drinking water production due to its effectiveness to inactivate microorganisms such as Crytosporidium parvum without forming disinfection byproducts. However, UV disinfection is known for its drawback such as photoreactivation. Despite many works concerning the photoreactivation, most of works were focused on indicator or non pathogenic microorganisms. The objective of this study is to examine the photoreactivation of Pseudomonas aeruginosa which is an opportunistic pathogen as UV radiation by LP and MP UV lamp was applied. The result showed that P. aeruginosa had high photo repair efficiency regardless of the type of UV irradiation. Both of the effective log repair values of LP and MP UV irradiation were found approximately 2.6 log. In addition, photo repaired P. aeruginosa was not significantly different in forming biofilm in comparison with non treated P. aeruginosa.

Clinical Application of Serum Tumor Abnormal Protein (TAP) in Colorectal Cancer Patients

  • Wu, Xue-Yan;Huang, Xin-En
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.8
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    • pp.3425-3428
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    • 2015
  • Objective: To explore the association of serum tumor abnormal protein (TAP) with other serological biomarkers e.g. carcinoembryonic antigen (CEA), carbohydrate antigen 125 (CA125), carbohydrate antigen 19-9 (CA19-9) and its clinical application in colorectal cancer (CRC) patients. Methods: Patients (N=98) were enrolled into this study with histologically or cytologically confirmed CRC. Using a test kit, the level of TAP was determined, while chemiluminescence was used to measure the levels of some other common serological biomarkers e.g. CEA, CA125 and CA19-9. Results: The area of TAP condensed particulate matter decreased after chemotherapy compared with before chemotherapy when CT or MRI scans showed disease control. In contrast, it increased with disease progression (P<0.05). Furthermore, a statistically significant difference was confirmed in monitoring of TAP and common serological biomarkers e.g. CEA and CA19-9 (p<0.05). Conclusions: Detecting TAP in CRC patients has high sensitivity and specificity and can be used as a new independent indicator for clinically monitoring CRC patients in the course of chemotherapy.

Development of quantitative index evaluating anticancer or carcinogenic potential of diet: the anti-cancer food scoring system 1.0

  • Rim, Chai Hong
    • Nutrition Research and Practice
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    • v.12 no.1
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    • pp.52-60
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    • 2018
  • BACKGROUND/OBJECTIVE: Cancer is closely related to diet. One of the most reliable reports of the subject is the expert report from the World Cancer Research Fund & American Institute of Cancer Research (WCRF&AICR). However, majority of the studies including above were written with academic terms and in English. The aim of this study is to create a model, named Anti-Cancer Food Scoring System (ACFS), to provide a simple index of the anticancer potential of food. SUBJECTS/METHODS: We created ACFS codes of various food groups. The evidence of the ACFS codes was provided by the literature at a level comparable to that suggested in the WCRF&AICR report or from the WCRF&AICR report. The ACFS grade was calculated considering food group, cooking, and normalization. Application was performed for Koreans' 20 common meals, which encompass multinational recipes. RESULT: We calculated the ACFS grades of Koreans' 20 common meals. The results were not significantly different from the WCRF&AICR guidelines or information from the National Cancer Information Center of Korea. The grades were briefly interpreted as follows: grade S. ideal for cancer prevention; grade A. good for cancer prevention; grade B, might have anticancer potential; grade C, difficult to be regarded as preventive or carcinogenic; grade D, might against cancer prevention; grade E, probably against cancer prevention. CONCLUSIONS: The ACFS provides a simple index of anticancer potential of diets. This indicator can be useful for the people without expertise, and is effective in evaluating the diets including Asian foods. The ACFS can help design of future clinical or nutritional studies of cancer prevention.

Dynamics of shearing force and its correlations with chemical compositions and in vitro dry matter digestibility of stylo (Stylosanthes guianensis) stem

  • Zi, Xuejuan;Li, Mao;Zhou, Hanlin;Tang, Jun;Cai, Yimin
    • Asian-Australasian Journal of Animal Sciences
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    • v.30 no.12
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    • pp.1718-1723
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    • 2017
  • Objective: The study explored the dynamics of shearing force and its correlation with chemical compositions and in vitro dry matter digestibility (IVDMD) of stylo. Methods: The shearing force, diameter, linear density, chemical composition, and IVDMD of different height stylo stem were investigated. Linear regression analysis was done to determine the relationships between the shearing force and cut height, diameter, chemical composition, or IVDMD. Results: The results showed that shearing force of stylo stem increased with plant height increasing and the crude protein (CP) content and IVDMD decreased but fiber content increased over time, resulting in decreased forage value. In addition, tall stem had greater shearing force than short stem. Moreover, shearing force is positively correlated with stem diameter, linear density and fiber fraction, but negatively correlated with CP content and IVDMD. Conclusion: Overall, shearing force is an indicator more direct, easier and faster to measure than chemical composition and digestibility for evaluation of forage nutritive value related to animal performance. Therefore, it can be used to evaluate the nutritive value of stylo.

The Effect of Auricular Acupuncture on the Pulse Rate (이침 요법이 맥박의 변화에 미치는 영향)

  • Jang, Jun-hyouk;Kim, Ji-young
    • Journal of Acupuncture Research
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    • v.20 no.1
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    • pp.97-103
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    • 2003
  • Objective : Auricular acupuncture is a method of treatment that involves needling the ear in order to produce relief of symptoms. This concept was first developed by P.Nogier, french doctor and referred to as somatotopic representation. Many authors have commented the fact that the vagus nerve supplies the external auditory and the concha. The aim of this randomised, single blind study was to investigate whether auricular acupuncture of the ear produced changes in the pulse rate, an indicator of vagal tone. Methods: 10 healthy man volunteers were divided into normal and epinephrine stimulation group. Then each group was divided into vagus area acupuncture and control area acupuncture group again. Epinephrine stimulation group was injected by epinephrine 0.3cc twice, first. All of them were needled in either the vagus area or control area of the ear, and pulse rate changes were measured by patient monitor over 1 hour. Results : In the epinephrine stimulation group, there was significant differences in the pulse rate change between vagus area acupuncture and control area acupuncture group. After injection of epinephrine, the basal pulse rate was increased 1.3~1.4 times in the control group. However, in the vagus area acupuncture group the basal pulse rate was increased only 1.1~1.2 times.

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SENSITIVITY ANALYSIS ABOUT THE METHODS OF UTILIZING THE HIGH RESOLUTION CLIMATE MODEL SIMULATION FOR KOREAN WATER RESOURCES PLANNING (I) : THEORETICAL METHODS AND FORMULATIONS

  • Jeong, Chang-Sam;Lee, Sang-Jin;Ko, Ick-Hwan;Heo, Jun-Haeng;Bae, Deg-Hyo
    • Water Engineering Research
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    • v.6 no.2
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    • pp.63-71
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    • 2005
  • Nowadays Climate disasters are frequently happening due to occasional occurrences of EI Nino and La Nina events and among them, water shortage is one of the serious problems. To cope with this problem, climate model simulations can give very helpful information. To utilize the climate model for enhancing the water resources planning techniques, probabilistic measures of the effectiveness of global climate model (GCM) simulations of an indicator variable for discriminating high versus low regional observations of a target variable are proposed in this study. The objective of this study is to present the various analysis methods to find the suitable application methods of GCM information for Korean water resources planning. The basic formulation uses the significance probability of the Kolmogorov-Smirnov test for detecting differences between two variables. The various methods for adopting correct association, changing the window size, discrimination condition, and the use of temporally down scaled data were proposed to find out the suitable way for Korean water resources planning.

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Calibration of Fatigue Performance Prediction Model for Flexible Pavements Using Field Data (현장 데이터를 이용한 연성포장용 피로 공용성 예측모델 검정)

  • Kim, Nakseok
    • Journal of the Society of Disaster Information
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    • v.8 no.3
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    • pp.234-241
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    • 2012
  • The main objective of this research is to calibrate the performance prediction models for the growth of fatigue cracking in multi-layered asphalt concrete pavement systems. However, the calibration factors are dependent upon the prediction model, testing method, and the laboratory loading history. A detailed study on the field data has revealed that the performance of flexible pavements is affected by both the traffic loading and the environmental cycling which is related to the age of the pavements. Thus, a composite indicator was developed in this study which utilizes both the traffic and the age information with appropriate weighting factors. Using the proposed fatigue performance model the calibration factors were also estimated through the comparisons between the field performances on fatigue cracking and the laboratory-based fatigue life.