• The Journal of Pediatrics of Korean Medicine
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• v.17 no.2
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• pp.55-74
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• 2003

Objective : The purpose of this study was to investigate the back shape and self-conscious symptoms of the students in S High school using the phase-shifting scanning grating projection Moire interferometer and Questionnaire investigations. Methods : In this study the subjects consisted of 317 pupils[168 boys(53%), 149girls(47%)] attending S high school in Sungnamsi, Kyoungkido in 2002. Their ages ranged from sixteen to eighteen. With the phase-shifting scanning grating projection moire interferometer, the posterior views of the body were taken to see if there are correlation of remainder value of the height spot of left & right shoulder blade and gluteal region in Moire topography. And using questionnaire investigation, we investigated the self-conscious symptoms. Results : 1. In questionnaire investigation, we observed that the ratios of self-conscious symptoms of girls are more than that of boys. The ratios of headache, neck pain, lower back pain, digestive symptom were more than 70% in boys and girls. 2. In Moire topography, more frequent findings of scapular region were observed that left scapular area were higher than right(in boys 69.3%, 60%, 100%, aged 16,17,18, in girls 66.8%, 40.5%, 58.8% aged 16,17,18). 3. More frequent findings of gluteal region were observed that left scapular area were higher than right(in boys 75.2%, 60%, 36.4% aged 16,17,18, in girls 61.1%, 46.8%, 64.7% aged 16,17,18) 4. More frequent findings of reminder value of the vertical lines of cervical and buttock region in Moire topography were observed that the vertical lines of cervical region were inclined to left than the vertical lines of buttock(in boys 73.3%, 92.2%, 100% aged 16,17,18, in girls 72.2%, 77.2%, 73.5% aged 16,17,18) Conclusion : From these results, we found that the self-conscious symptoms were more than in girls than boys; the ratio of headache, neck pain, Lower back pain, digestive symptom was more than the others; the back shape of high school students were not balanced in scapular and buttock region; necks were inclined to left than buttock.

• Animal Bioscience
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• v.37 no.3
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• pp.461-470
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• 2024

Objective: The objective of this study was to investigate the genetic diversity, population structure and whole-genome selection signatures of Luxi cattle to reveal its genomic characteristics in terms of meat and carcass traits, skeletal muscle development, body size, and other traits. Methods: To further analyze the genomic characteristics of Luxi cattle, this study sequenced the whole-genome of 16 individuals from the core conservation farm in Shandong region, and collected 174 published genomes of cattle for conjoint analysis. Furthermore, three different statistics (pi, F_st, and XP-EHH) were used to detect potential positive selection signatures related to selection in Luxi cattle. Moreover, gene ontology and Kyoto encyclopedia of genes and genomes pathway enrichment analyses were performed to reveal the potential biological function of candidate genes harbored in selected regions. Results: The results showed that Luxi cattle had high genomic diversity and low inbreeding levels. Using three complementary methods (pi, F_st, and XP-EHH) to detect the signatures of selection in the Luxi cattle genome, there were 2,941, 2,221 and 1,304 potentially selected genes identified, respectively. Furthermore, there were 45 genes annotated in common overlapping genomic regions covered 0.723 Mb, including PLAG1 zinc finger (PLAG1), dedicator of cytokinesis 3 (DOCK3), ephrin A2 (EFNA2), DAZ associated protein 1 (DAZAP1), Ral GTPase activating protein catalytic subunit alpha 1 (RALGAPA1), mediator complex subunit 13 (MED13), and decaprenyl diphosphate synthase subunit 2 (PDSS2), most of which were enriched in pathways related to muscle growth and differentiation and immunity. Conclusion: In this study, we provided a series of genes associated with important economic traits were found in positive selection regions, and a scientific basis for the scientific conservation and genetic improvement of Luxi cattle.

• Journal of Korean society of Dental Hygiene
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• v.7 no.4
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• pp.365-379
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• 2007

The objective of the current study is to provide basic data necessary for the development of systematic program that is required for the systematic occupational work training of dental hygienists who newly employed at dental hospitals or clinics. The results of the surveys were listed as in below. The survey was conducted for 175 experienced dental hygienists who are in charge of occupational work training in 6 regions(Seoul, Kyunggi, Busan, Ulsan, Kwangju, Chungnam, Kyungnam) of the country where the occupational work training for new dental hygienists is systematically operated. 1. The recognition of experienced dental hygienists for the importance of occupational work training revealed that image training was the most importantly recognized by dental hygienists in Seoul Kyunggi regions(pE.01). In case of Busan region, periodontic training and conservative dentistry training were the most importantly recognized, and customer service training was mostly highly recognized in Ulsan region(pE.01). In case of Kwangjuregion, dental health insurance claim training was recognized as most important subject, and Patient consultation training was the most importantly recognized in Chungnam region. In case of Kyungnam region. Oral surgery was recognized as the most important training subject. 2. Regard on the importance of the range of occupational work training, the experienced dental hygienists with less than 2 years of experience were found to recognize the training of greeting and naming most importantly, the dental hygienists with 2~3 years of experience most importantly recognized oral surgery, and the dental hygienists with 4~5 year of experience were found to recognize conservative training most importantly. In case of dental hygienists having 6~9 year of experience recognized periodontic and conservation trainings as the most important subjects, and the dental hygienist having more than 10 years of experience were found to recognize conservative and image trainings mostly importantly.

• The Journal of Korean Physical Therapy
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• v.17 no.2
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• pp.107-125
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• 2005

The term of TOS(thoracic outlet syndrome) is used to describe patients with compressed subclavian artery, subclavian vein, and the brachial plexus in the region of the thoracic outlet. The objective of this study was to evaluate a conservative physical therapy that aims to restore normal function to the upper aperture in patients with TOS. The efficacy of this study which is conservative physical therapy, was assessed by pain, grip power, pinch grip, and satisfaction level of patients. The results were as follow; 1. Pain(VAS) was statistically significant with Group 1 and Group 2(P<0.05), and Group 2 was more statistically significant than Group 1(P<0.05). 2. Spherical grip was statistically significant with Group 1 and Group 2(P<0.05), and Group 2 was more statistically significant than Group 1(P<0.05). 3. Pinch grip was statistically significant with group 1 and Group 2(P<0.05), and Group 2 was more statistical significance than Group 1(P<0.05). 4. Satisfaction level was statistically significant with group 1 and Group 2(P<0.05), and Group 2 was more statistically significant than Group 1(P<0.05).

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.8
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• pp.3541-3546
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• 2014

TEL-AML1 fusion oncogene (t 12; 21) is the most common chromosomal abnormality in childhood acute lymphoblastic leukemia (ALL). This translocation is associated with a good prognosis and rarely shows chemotherapeutic resistance to 3-drug based remission induction phase of treatment as well as overall treatment. Thus, the higher the frequency of this fusion oncogene, the easier to manage childhood ALL in a given region with less intensive chemotherapy. Although global frequency of TEL-AML1 has been reported to be 20-30%, a very low frequency has been found in some geographical regions, including one study from Lahore, Punjab, Pakistan and others from India. The objective of present study was to investigate if this low frequency of TEL-AML1 in pediatric ALL is only in Lahore region or similar situation exists at other representative oncology centers of Pakistan. A total of 167 pediatric ALL patients were recruited from major pediatric oncology centers situated in Lahore, Faisalabad, Peshawar and Islamabad. Patients were tested for TEL-AML1 using nested reverse transcription polymerase chain reaction (RT-PCR). Only 17 out of 167 (10.2%) patients were found to be TEL-AML1 positive. TEL-AML1+ALL patients had favorable prognosis, most of them (82.4%, 14/17) showing early remission and good overall survival. Thus, our findings indicate an overall low frequency of TEL-AML1 in Pakistan pediatric ALL patients, in accordance with lower representation of this prognostically important genetic abnormality in other less developed countries, specifically in south Asia, thus associating it with poor living standards in these ethnic groups. It also indicates ethnic and geographical differences in the distribution of this prognostically important genetic abnormality among childhood ALL patients, which may have a significant bearing on ALL management strategies in different parts of the world.

• Asian-Australasian Journal of Animal Sciences
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• v.29 no.3
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• pp.315-320
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• 2016

Porcine beta-defensin-1 (PBD-1) gene plays an important role in the innate immunity of pigs. The peptide encoded by this gene is an antimicrobial peptide that has direct activity against a wide range of microbes. This peptide is involved in the co-creation of an antimicrobial barrier in the oral cavity of pigs. The objective of the present study was to detect polymorphisms, if any, in exon-1 and exon-2 regions of PBD-1 gene in Large White Yorkshire (LWY) and native Ankamali pigs of Kerala, India. Blood samples were collected from 100 pigs and genomic DNA was isolated using phenol chloroform method. The quantity of DNA was assessed in a spectrophotometer and quality by gel electrophoresis. Exon-1 and exon-2 regions of PBD-1 gene were amplified by polymerase chain reaction (PCR) and the products were subjected to single strand conformation polymorphism (SSCP) analysis. Subsequent silver staining of the polyacrylamide gels revealed three unique SSCP banding patterns in each of the two exons. The presence of single nucleotide polymorphisms (SNPs) was confirmed by nucleotide sequencing of the PCR products. A novel SNP was found in the 5'-UTR region of exon-1 and a SNP was detected in the mature peptide coding region of exon-2. In exon-1, the pooled population frequencies of GG, GT, and TT genotypes were 0.67, 0.30, and 0.03, respectively. GG genotype was predominant in both the breeds whereas TT genotype was not detected in LWY breed. Similarly, in exon-2, the pooled population frequencies of AA, AG, and GG genotypes were 0.50, 0.27, and 0.23, respectively. AA genotype was predominant in LWY pigs whereas GG genotype was predominant in native pigs. These results suggest that there exists a considerable genetic variation at PBD-1 locus and further association studies may help in development of a PCR based genotyping test to select pigs with better immunity.

• Journal of Agricultural Extension & Community Development
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• v.5 no.1
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• pp.93-102
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• 1998

The objectives of the study were 1) to make the reasonable standard, 2) to select the objective and scientific method and process for the location-allocation of a new provincial capital city. The Main standard of location-allocation were suggested as follows ; 1) Integration of province 2) Convenience of Administration service 3) Accomodations of new provincial capital city 4) Balanced development by region. The validity of location-allocation were reviewed the population potentials and nodal accessibilities. The population potential was examined to find the maximum point of administrative demand, and the locationallocation model was examined to find the minimum point of the aggregated travel-cost to a proposed provincial government office. The nodal accessibilities measured in travel-time distance and actual values. Two major concerns in locating public facilities are efficiency and equity.

• Animal Bioscience
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• v.37 no.3
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• pp.509-521
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• 2024

Objective: It was shown that microRNAs (miRNAs) play an important role in milk protein synthesis. However, the post-transcriptional regulation of casein expression by exogenous miRNA (xeno-miRNAs) in ruminants remains unclear. This study explores the regulatory roles of alfalfa xeno-miR162 on casein synthesis in bovine mammary epithelial cells (bMECs). Methods: The effects of alfalfa xenomiR-162 and G protein subunit gamma 11 (GNG11) on proliferation and milk protein metabolism of bMECs were detected by 5-Ethynyl-2'-Deoxyuridine (EdU) staining, flow cytometry, cell counting kit-8 (CCK-8), enzyme-linked immunosorbent assay, quantitative real-time polymerase chain reaction (qRT-PCR), and Western blot. Dual-luciferase reporter assay was used to verify the targeting relationship between GNG11 and xenomiR-162. Results: Results showed that over-expression of xenomiR-162 inhibited cell proliferation but promoted apoptosis, which also up-regulated the expression of several casein coding genes, including CSN1S1, CSN1S2, and CSN3, while decreasing the expression of CSN2. Furthermore, the targeting relationship between GNG11 and xenomiR-162 was determined, and it was confirmed that GNG11 silencing also inhibited cell proliferation but promoted apoptosis and reduced the expression of casein coding genes and genes related to the mammalian target of rapamycin (mTOR) pathway. Conclusion: Alfalfa xenomiR-162 appears to regulate bMECs proliferation and milk protein synthesis via GNG11 in the mTOR pathway, suggesting that this xeno-miRNA could be harnessed to modulate CSN3 expression in dairy cows, and increase κ-casein contents in milk.

• Solar Energy
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• v.15 no.1
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• pp.85-94
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• 1995

This research has been proceeded over the potential core region(H/B=2) of two-dimensional impinging air jet sytem, in which square rods(width of 6 mm) has been set up in front of heating surface in order to increase heat transfer. The objective of this research was to investigate the characteristics of heat transfer and air flow, in eases of the clearance from rods to heating surface(C=1, 2, 4, 6 mm) and the pitch between each rods(P=30, 40, 50 mm) changed. And this research compared the above with the experimentation without rods. As result, heat transfer performance was best under the condition of C=1mm, in case clearance changed, and there was no serious difference in the effect of heat transfer augmentation in the case of pitch of rods changed.

• Journal of Korean Neurosurgical Society
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• v.51 no.5
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• pp.253-261
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• 2012

Objective : This study was performed to determine the anatomical landmarks and optimal dissection points of the facial nerve (FN) and the hypoglossal nerve (HGN) in the submandibular region to provide guidance for hypoglossal-facial nerve anastomosis (HFNA). Methods : Twenty-nine specimens were obtained from 15 formalin-fixed adult cadavers. Distances were measured based on the mastoid process tip (MPT), common carotid artery bifurcation (CCAB), and the digastric muscle posterior belly (DMPB). Results : The shortest distance from the MPT to the stylomastoid foramen was $14.1{\pm}2.9$ mm. The distance from the MPT to the FN origin was $8.6{\pm}2.8$ mm anteriorly and $5.9{\pm}2.8$ mm superiorly. The distance from the CCAB to the crossing point of the HGN and the internal carotid artery was $18.5{\pm}6.7$ mm, and that to the crossing point of the HGN and the external carotid artery was $15.1{\pm}5.7$ mm. The distance from the CCAB to the HGN bifurcation was $26.6{\pm}7.5$ mm. The distance from the digastric groove to the HGN, which was found under the DMPB, was about $35.8{\pm}5.7$ mm. The distance from the digastric groove to the HGN, which was found under the DMPB, corresponded to about 65.5% of the whole length of the DMPB. Conclusion : This study provides useful information regarding the morphometric anatomy of the submandibular region, and the presented morphological data on the nerves and surrounding structures will aid in understanding the anatomical structures more accurately to prevent complications of HFNA.