• Journal of Korean Neurosurgical Society
• /
• v.40 no.5
• /
• pp.342-345
• /
• 2006

Objective : Gamma Knife Surgery[GKS] for the management of pineal region tumors is challengeable strategy as direct access to this area is not easy. The experiences of pineal region tumor patients treated with GKS were analyzed to evaluate the effectiveness. Methods : Seven patients with tumors in the pineal region were treated with GKS between September 1998 and May 2005. The histological diagnosis were pineal parenchymal tumor [2 patients], low-grade astrocytoma [2 patients], immature teratoma [1 patient], and choriocarninoma [1 patient]. One patient was diagnosed as metastatic brain tumor based on histological diagnosis for primary site and brain imaging study. The median marginal dose was 15Gy [range; $11{\sim}20$] at the 50% isodose line. The median target volume was $2.5cm^3$ [range; $0.8{\sim}12.5$]. The median clinical follow up period was 29 months [range; $13{\sim}93$] and the median radiological follow up period was 18 months [range; $6{\sim}73$]. Results : Tumor volume measured in follow-up images showed reduction in six patients, disappearance in one. No adverse effect due to GKS was found during the follow-up period. The performance status was preserved in all patients except one who died due to progression of primary cancer in spite of controlled metastatic brain lesion. Conclusion : Gamma Knife Surgery can be applied to pineal region tumors irrespective of their histology whenever surgery is not indicated.

• Journal of Families and Better Life
• /
• v.18 no.1
• /
• pp.53-66
• /
• 2000

This study examined the relationships among resources demands financial management behavior and financial satisfaction of housewives based on the systems approach. The data were collected from 212 housewives living in Pusan and Kyungnam region by the self-administered questionnaire. The major findings of this study were as follows: (1) the communication frequency of husbands and wives was an important factor affecting financial satisfaction; (2) the perceived financial status such as comparison to reference groups and aspiration for financial status in the future had an influence on financial satisfaction as well as the objective variables such as monthly living costs and monthly savings; and (3)financial satisfaction was also affected by financial management behavior. These findings imply that the financial management program focusing on the ways to increase communication among family members and to implement financial behavior effectively should be developed.

• Nuclear Engineering and Technology
• /
• v.29 no.1
• /
• pp.85-91
• /
• 1997

Cross-flow existing in a shell-and-tube steam generator can cause a tube to vibrate. There are four regions subjected to cross-flow in Yonggwang units 3 and 4 (YGN 3 and 4) steam generators, which are of the same design as the steam generators for Palo Verde nuclear power plant Palo Verde units 1 and 2 steam generators have experienced localized oar at the comers of the cold side recirculating fluid inlet regions. A number of design modifications were made to preclude tube failure in specific regions of YGN 3 and 4 steam generators. Therefore, flow induced vibration experiments were done to determine the vibration magnitude of tubes in the economizer tube free lane region. The objective of this experiment is to demonstrate that the tube displacement is less than 0.01 inch rms at 100% of full power flow and to quantify the remaining design margin at 120ft and 140% of full power flow.

• The korean journal of orthodontics
• /
• v.38 no.2
• /
• pp.133-143
• /
• 2008

Objective: This study was performed to identify the characteristics of the MSX1 gene (locus chromosome 4p16) in Korean nonsyndromic cleft lip and palate (CL/P), which is assumed to be a major candidate gene acting as a causal factor in nonsyndromic CL/P and missing teeth. Methods: The 36 individuals (23 males and 13 females) who had visited the department of orthodontics at from 1998 to 2002 and who had nonsyndromic CL/P were included in the study. Using a PCR-based assay, the MSX1 gene was amplified, sequenced, and searched for inferred protein products (Reference: Homo sapiens MSX1, accession number AF426432 and NP_002439). The common single nucleotide polymorph isms were observed. Results: In exon 1, nucleotide "A" of the 253 basepair (bp) region was substituted for "G", and in the 255 bp region, nucleotide "G" was inserted. In exon 2, nucleotide "C" of the 11 bp region was substituted for "A", and "T" or "G" was inserted into the 351 bp region whereas "T" or "A" was inserted into the 352 bp region. In protein analysis, "Thr85Ala" missense mutation was found. The "Thr85Ala" missense mutation in this study is different from those of studies using subjects of other races. Conclusions: The results suggest that there is specific mutation of MSX1 in Korean and it plays an important role in Korean nonsyndromic CL/P. However, any distinct genetic polymorphisms between CL/P with missing teeth in the cleft region and CL/P without missing teeth could not be found.

• Atmosphere
• /
• v.16 no.2
• /
• pp.67-83
• /
• 2006

The statistical analysis for the springtime windstorm in Korea shows that Yeongdong region has the highest occurrence frequency during recent 10 years. The objective of this study is to find possible mechanisms for the downslope windstorm formation in the Yeongdong region by using a mesoscale numerical model, WRF. Dynamical process, wave breaking (hereafter WB), is qualitatively investigated as the candidate mechanism for a windstorm event occurred in 5 April, 2005. WB is developed in upper troposphere downstream, since stable air is lifted by the Taebaek mountain. This process can cause and maintain the severe downslope windstorm by drawing the upper flow down to the surface. And the intensified downslope wind leads the hydraulic jump (hereafter HJ) in downstream region. Froude numbers at Chuncheon (upslope side), Seorak Mountain (crest), Yangyang (lee side), and the East Sea (distant downstream position) are estimated by about 0.4, 1.0, 1.6, and 0.6, respectively. This result implies that the accelerated and supercritical (Fr>1) flow adjusts to the ambient subcritical (Fr<1) conditions in the turbulent HJ. In addition, we find the formation of upstream inversion near top level of the mountain cause the intensification of HJ. Experiments to examine the orographic effect on the mechanisms suggest that the magnitudes of WB and HJ are larger in the experiment of higher topography, but there is no significant difference of windstorm magnitude among the experiments. Another important result from these sensitivity experiments is that the intensity of downslope windstorm strongly depends on the magnitude of upper (2~4 km) wind in upstream side.

• Journal of Korean Society of Rural Planning
• /
• v.20 no.4
• /
• pp.25-33
• /
• 2014

This study has intended to build a rural landscape evaluation model based on an integrated landscape assessment paradigm of rural region using an additive integration index method and applied the model to the Seondong Region of Gochang-gun, Jeollabuk-do, Korea. To reach this goal, this study developed a model to calculate Integrated Landscape Assessment Index. The model has employed the Objective Landscape Index, the Subjective Landscape Index, and the weighted values, and was applied to the Seondong region. This study has found the following results: 1) forests and water spaces were assessed with relatively better visual preferences and better landscape ecosystem; 2) the historic cultural area and scenic agriculture as well as general farm land were assessed with moderate ratings; and, 3) the villages included in development plan, their adjacent arable farming land, and the village watercourses were forming relatively poorer landscape.

• Proceedings of KOSOMES biannual meeting
• /
• 2008.05a
• /
• pp.169-171
• /
• 2008

The objective of this paper is to explore the short-term variability of sea surface temperature (SST) and chlorophyll a (Chl-a) derived from satellite in the upwelling region of the southeast coast of Korea in summer. We particularly emphasize the spatial variability of SST and Chl-a in the East Korean Warm Current (EKWC) during summer monsoon. Spatial distribution of SST and Chl-a in the EKWC are described using SeaWiFS and AVHRR images in August, 2007. Spatial distribution of SST and Chl-a around EKWC can be classified into four categories in the profile of SST and Chl-a images: (1) coastal cold water region, (2) cold water region of thermal front, (3) warm water region, (4) cold water of offshore region.

• Asian Pacific Journal of Cancer Prevention
• /
• v.17 no.12
• /
• pp.5217-5221
• /
• 2016

Objective: A study of primary cancer morbidity among children and subsequent calculation of average annual incidence were carried out for boys and girls, and young men and women in Kazakhstan. Methods: The investigated population lived in three areas of the Aral Sea region: designated catastrophe (Aral, Kazalt, Shalkar regions), crisis (Zhalagash, Karmakshy, Shiely regions), pre-crisis (Irgiz, Arys, Ulytau regions). Zhanaarka region of Karaganda oblast was applied as a control. Parameters were retrospective analyzed for the 10 years from 2004 to 2013. Result: The results indicate that indices of children cancer morbidity were slightly higher in the Aral Sea region than in the control district, but they were comparable with similar data from studies in other regions. In all areas of the Aral Sea region, except for Ulytau, primary cancer morbidity exceeded the control level by 1.3-2.7 times (4.7%000). Hematological malignancies, including solid tumors - tumors of musculoskeletal system and skin, digestive system, brain and central nervous system predominated. Stress levels in zones of the Aral Sea region were slightly higher in the crisis zone than in the catastrophe zone that can be explained by the phenomenon of wave-like dynamics of disease growth risk. Gender differences in characteristics of malignancy formation were not more pronounced in the studied region. Conclusion: Indices of children cancer are slightly higher in the Aral Sea region than in the control area of Kazakhstan, but they are comparable to results for other regions.

• Maxillofacial Plastic and Reconstructive Surgery
• /
• v.32 no.1
• /
• pp.57-61
• /
• 2010

Objective: Second primary malignancy (SPM) that occur in various period and region are important factors that deteriorate long-term survival rate in patients who recovered from oral cancer. Researches such as chemoprevention are being tried to reduce occurrence of SPMs. Only if analysis of clinical features of patients who develop SPM such as period, region and factors precedes, adequate prevention and treatment of SPM is possible. But, there are few researches about clinical features of SPMs that have primary lesion in oral cavity. In this study, we analysis that occurrence rates, regions that happen, risk factors and effect to survival rates of 2nd primary malignancies in oral cancer patients. From this survey, we willing to collect basic data for prevention and early diagnosis of SPMs. Methods: The medical records of 139 patients of oral oncology clinic of National Cancer Center who had up to 2-years follow up records after surgical or radiological treatment due to squamus cell carcinoma of oral cavity were reviewed. In these patients, survey of occurrence rate of SPMs, duration, survival rate and risk factors about occurrence of SPMs such as history of smoking, body mass index, age, sex, stage of primary lesion and history of radiologic treatment were achieved. Results: There are 15 patients who developed SPM in 139 cases. The actual occurrence rate of SPM was 10.79% and SPM were more likely to occur in male patients with 11 male Vs 4 female patients. Median age of these patient is 61.47 within 32 to 74 range. The regions that develop SPM are oral cavities (2 cases), stomach (4 cases), esophagus (2 cases), lung (2 cases) and others (1 case each breast, larynx, cervix, liver and kidney). In addition, metachronous cancers were 11 cases which happened more common than 4cases of synchronous cancers. Surveys of risk factors that relate to development of SPMs, such as sex, age, history of radiologic treatment, body mass index, history of smoking and stage of primary disease were done. Among them, factor of sex is only appear statistically significant (P=0.001), but rest are not significant in statistically. Conclusion: Occurrence rates of SPMs were reported from 10% to 20% by precede study. In this study, occurrence rate of SPMs is 10.79% that is similar to results of precede research. In comparison of 5-yr survival rates of groups that develop SPMs or not, there is statistically significance between two groups. Present treatment modalities of SPMs are surgical operation, radiotherapy, chemotherapy and combination of these modalities. In choosing the treatment modality, we must consider the first treatment modality, region of primary disease, region of SPMs and general conditions of patient. Because development of SPMs have big effect on prognosis, prevention of SPMs must regard to important objective of treatments in patients of SCCa in oral cavity.

• Journal of computational fluids engineering
• /
• v.17 no.2
• /
• pp.1-10
• /
• 2012

This paper presents the numerical simulation results of heat transfer and friction loss for a rotating two-pass duct with the airfoil-guide vanes in the turning region. The Kriging model is used as an optimization technique with Reynolds-averaged Navier-Stokes analysis of flow field and heat transfer with shear stress transport turbulent model. To improve the heat transfer performance, angle and location of the airfoil-guide vanes have been selected as design variables. The optimization problem has been defined as a minimization of the objective function, which is defined as a linear combination of heat transfer related term and friction loss related term with a weight factor. The airfoil-guide vanes in the turning region keep the high level of heat transfer while the friction loss has a low value. By comparing the presence or absence of airfoil-guide vanes, it is shown that the airfoil-guide vanes exhibited the best heat transfer performance to improve the blade cooling except the first passage.