• Archives of Obesity and Metabolism
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• v.2 no.2
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• pp.71-75
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• 2023

Obesity is closely related to chronic diseases and cancer. The present case report aims to discuss the anti-obesity treatment strategy and the evaluation of the clinical progress in a patient with obesity and concurrent fatty liver disease. Following five months of treatment with liraglutide and rosuvastatin, the patient had a weight reduction of 3 kg (4.7%), a decrease in fasting blood sugar by 42 mg/dl (26.6%), a decrease in low-density lipoprotein cholesterol by 82 mg/dl (60.2%), and decrease in alanine transaminase. This case report documented the treatment of a patient with common chronic diseases encountered in the outpatient setting. Based on the therapeutic effects documented in clinical and laboratory indices, the anti-obesity treatment plan significantly aided in managing chronic diseases.

• Korean Journal of Oriental Medicine
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• v.16 no.1
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• pp.119-134
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• 2010

Objectives & Method：Based on the statistic from January 2008 to December 2008 include 66-year-old 375 people (159 men, 216 women) who got examined in National Health Insurance Corporation, this study set a goal to establish a new health index by analyzing the relation between the cardio-cerebra vascular disease and risk factor such as obesity, smoking, exercise, alcohol consumption, blood pressure, blood sugar and cholesterol. Results：1) Examine results, health status according to gender；People who are diagnosed as abnormal health status have higher risk for both men and women. As for the detailed diseases, high blood pressure was highest followed by hyperlipidemia and obesity. In case of the women, 96.3% in bone mineral density was highest. 2) Correlation of disease and health risk factors based on gender；Correlation of disease according to gender in the obesity(p<0.001), lipid abnormalities(p<0.001), kidney diseases(p<0.001), chest diseases(p<0.05), osteoporosis(p<0.001) showed a statistically significant difference. The analysis showed that the men have more obesity and lipid abnormalities as well as thoracic disease than the women, but the women have more kidney disease than the men. As for the osteoporosis examine which is conducted only for the women, most of the women were abnormal even though it cannot compare the result according to gender. Obesity(p<0.001), alcohol(p<0.001), smoking(p<0.001) and LDLcholesterol(p<0.001) showed statistical correlation between gender and health risk factor. And only high blood pressure(p<0.001) showed a statistical correlation between gender and risk of cardio-cerebra vascular disease. 3) Risk of cardio-cerebra vascular disease related to health risk factor characteristic；Obesity assessment(p<0.001), alcohol(p<0.05), smoking(p<0.05), blood pressure(p<0.001), glucose(p<0.001) showed correlation between health risk factor and stroke. Drinking(p<0.001), smoking(p<0.05), exercise(p<0.001), blood pressure(p<0.001), LDL cholesterol(p<0.001) showed health risk factor and myocardial infarction. Obesity assessment(p<0.001), smoking(p<0.05), blood pressure(p<0.001), glucose(p<0.001) and showed correlation between health risk factor and diabetes. Obesity assessment(p<0.001), blood pressure(p<0.001) showed correlation between health risk factor and high blood pressure. Conclusion：Therefore, we have to take one step farther after the health examination. In order to prevent and reduce the risk of disease, people have to understand their health status exactly first, and correct their habit with recognizing the amount of risk related to cardio-cerebra vascular disease.

• Journal of Nutrition and Health
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• v.26 no.9
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• pp.1071-1084
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• 1993

This study was performed to investigate the relationships between obese index and major risk factors of cardiovascular disease in CVD patients. Anthropometry, food intake patterns, blood pressure, serum lipids and hematological values were analyzed in 550 patients from June, 1991 to August, 1992. The results are as follows: Total food intakes, especially total vegetable food and alcohol intakes were significantly related with obese index, so that the heavier patients tended to consume more carbohydrate and less fat. The blood pressure were observed to have positive correlation with obese index in man but not in women. However, both in men and women, blood levels of TG, TC, and VLDL tended to be related to obese index positively, while HDL and HDL-C were shown to be oppositive. So, it seems that as the degree of obesity is higher the blood pressure and blood lipids patterns worse. Therefore, these results suggest that obesity is one of the major risk factors of CVD, and for prevention & treatment of the disease, controlling body weight by nutritionally adequate diet along with alcohol restriction is necessary.

• Journal of Ginseng Research
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• v.45 no.3
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• pp.380-389
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• 2021

Metabolic syndrome (MS) refers to a clustering of at least three of the following medical conditions: high blood pressure, abdominal obesity, hyperglycemia, low high-density lipoprotein level, and high serum triglycerides. MS is related to a wide range of diseases which includes obesity, diabetes, insulin resistance, cardiovascular disease, dyslipidemia, or non-alcoholic fatty liver disease. There remains an ongoing need for improved treatment strategies for MS. The most important risk factors are dietary pattern, genetics, old age, lack of exercise, disrupted biology, medication usage, and excessive alcohol consumption, but pathophysiology of MS has not been completely identified. Korean Red Ginseng (KRG) refers to steamed/dried ginseng, traditionally associated with beneficial effects such as anti-inflammation, anti-fatigue, anti-obesity, anti-oxidant, and anti-cancer effects. KRG has been often used in traditional medicine to treat multiple metabolic conditions. This paper summarizes the effects of KRG in MS and related diseases such as obesity, cardiovascular disease, insulin resistance, diabetes, dyslipidemia, or non-alcoholic fatty liver disease based on experimental research and clinical studies.

• Journal of Korean Medicine Rehabilitation
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• v.31 no.4
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• pp.13-23
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• 2021

Objectives The purpose of this research is to comprehensively analyze about Jowiseungcheong-tang (Diàowèishēngqīng-tāng). This herbal medicine is widely used to treat obesity and metabolic disease. Methods We used 3 search terms, 'Jowiseungcheong-tang', 'Jowiseungcheong-tang plus obesity' and 'Jowiseungcheong-tang plus metabolic disease' in Korean word via 5 domestic databases. Therefore, 8 laboratory experiments and 4 clinical researches were chosen. Results Jowiseungcheong-tang (Diàowèishēngqīng-tāng) was identified as a herbal medicine for obesity and related metabolic disease. In plasma level of lipid, leptin, inflammatory material were decreased in laboratory experiments. Weight loss and symptom relief were reported in clinical research. Conclusions Definite information about laboratory experiment was showed, specifically suitable index and numerical value. In clinical research, although Jowiseungcheong-tang (Diàowèishēngqīng-tāng) is widely used for obesity and metabolic disease, the number of reported thesis and patient were pretty a few. Also, diagnosis methods were also scanty. Multi-institutional clinical trial should be progressed.

• Journal of Korean Medicine Rehabilitation
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• v.33 no.3
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• pp.129-134
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• 2023

Objectives The purpose of this study was to review the studies of catgut embedding related to obesity treatment. Methods We searched the papers with key words of obesity and catgut embedding via searching Research Information Sharing Service, DBpia, Koreanstudies Information Service System, Oriental Medicine Advanced Searching Integrated System, Scopus, PubMed. Additional data including study design, study topics, characteristics of participants and treatment, outcomes was extracted from full text of each study. Results There were nine studies about the catgut embedding related to obesity treatment. Five articles were conducted in China, two articles were conducted in Mexico, and two articles was published in Korea. Analysis of seven experimental studies and two observational studies were conducted to describe each research subject, method, and research results. Conclusions More interest and further research will be needed on catgut embedding related to obesity treatment in the Korean medicine to achieve clinical application and to develop treatment protocols for the obesity disease.

• Korean Journal of Health Education and Promotion
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• v.27 no.4
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• pp.83-90
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• 2010

objectives: This study was conducted to estimate medical expenditure attributable to overweight and obesity in adults with ischemic heart disease and stroke using Korea National Health and Nutrition Examination survey data and Korea National Health Corporation data. methods : The medical expenditure of ischemic heart disease and stroke related to overweight and obesity were composed of inpatient care costs, outpatient care costs and medication costs. The population attributable risk (PAR) of overweight and obesity was calculated from national representative data of Korea such as the National Health Insurance Corporation cohort data and 2005 Korea National Health and Nutrition Examination survey data. results: The medical expenditure attributable to overweight and obesity of ischemic heart disease were 97.4 billion won(74.1-122 billion won). and stroke were 64.6 billion won(33.1-98.1 billion won). Consequently, these costs corresponded to 11.4% of total medical expenditure due to ischemic heart disease and stroke. conclusion: We conclude that overweight and obesity have increased medical expenditure from ischemic heart disease and stroke in Korea. These findings provide important support for implementing overweight and obesity management strategies in Korea.

• Journal of Korean Biological Nursing Science
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• v.25 no.1
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• pp.32-42
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• 2023

Purpose: This study aimed to investigate the association between obesity and high-sensitivity C-reactive protein (hs-CRP) levels in Korean adults without cardiovascular disease (CVD). Methods: The subjects were 3,634 adults, and data were extracted from the seventh Korea National Health and Nutrition Examination Survey (KNHANES VII-3). A complex sampling design analysis was applied to reflect the stratified and clustered weights. The data were analyzed using the complex sample Rao-Scott chi-square test and multiple logistic regression analysis (in SPSS for Windows version 26.0). Obesity, according to body mass index (BMI), was defined as obesity (BMI = 25-29.9 kg/m²), high obesity (BMI = 30-34.9 kg/m²), and super-high obesity (BMI ≥ 35 kg/m²), and abdominal obesity (AO) was defined as a waist circumference (WC) ≥ 90 cm in males and WC ≥ 85 cm in females. Results: The odds ratios for moderate CVD risk (hs-CRP; 1-3 mg/dL) were 2.21, 4.16, and 7.13 in the obesity, high obesity, and super-high obesity groups, respectively, compared to the normal BMI group. The odds ratio for moderate CVD risk was 2.18 in males with AO and 1.88 in females with AO. The odds ratios for high CVD risk (hs-CRP > 3 mg/L) were 4.40 and 17.55 in the high obesity and super-high obesity groups, respectively, compared to the normal BMI group. Conclusion: This study provides evidence that early detection and prevention programs for CVD should include obesity-related interventions aiming to modulate hs-CRP.

• Journal of the Korea Convergence Society
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• v.10 no.6
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• pp.347-353
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• 2019

This study was a descriptive research to investigate the difference of obesity, smoking, drinking affected allergy disease in Korean adolescents using the raw data of $6^{th}$ Korea National Health and Nutrition Survey(2015). Study data on 535 Korean adolescents classified 12 to 18 years and Rao-Scott Chi-square test and logistic regression were used for analysis. The results of the study showed that the prevalence of asthma, atopic dermatitis, allergic rhinitis were 5.4%, 15.5%, 22.8% and not shown differences according obesity, smoking, drinking. But, the risk factor of asthma was related obesity, atopic dermatitis was related smoking. Based of this study's findings, It is necessary to develop the Heath Promotion Intervention Program according of obesity, drinking, smoking for the quality of life in adolescents diagnosed Allergy disease.

• East Asian mathematical journal
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• v.34 no.3
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• pp.317-330
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• 2018

We develop a mathematical model for the obesity dynamics to investigate the long term obesity trend with the consideration of psychological and social factors due to the increasing prevalence of obesity around the world. Many mathematical models for obesity dynamics adopted the modeling idea of infectious disease and treated overweight and obese people infectious and spreading obesity to normal weight. However, this modeling idea is not proper in obesity modeling because obesity is not an infectious disease. In fact, weight gain and loss are related to social interactions among different weight groups not only in the direction from overweight/obese to normal weight but also the other way around. Thus, we consider these aspects in our model and implement personal weight gain feature, a psychological factor such as body image dissatisfaction, and social interactions such as positive support on weight loss and negative criticism on weight status from various weight groups. We show that the equilibrium point with no normal weight population will be unstable and that an equilibrium point with positive normal weight population should have all other components positive. We conduct computer simulations on Korean demography data with our model and demonstrate the long term obesity trend of Korean male as an example of the use of our model.