• 동의생리병리학회지
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• 제21권4호
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• pp.934-939
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• 2007

In recent year, We are concerned about anti-aging, disease-prevention, longevity, so many methods are used in solving this problem. And Those are related with antioxidative ability. Recently, We heard that Mori Cortex was known to reduce the hypertension and was helpful in promoting health, and Mori Ramulus was effective against obesity, etc. So, This study was performed to investigate the antioxidative effect of hot-water extracts of Mori Cortex and Mori Ramulus used for 3 methods, those are DPPH radical scavenging activity, Nitric oxide(NO) radical scavenging activity and Bovine serum albumin(BSA). And we compared Mori Cortex and Mori Ramulus on Antioxidative Effects. The results of this study were as follows: We measured levels of DPPH radical scavenging activity and Nitric oxide(NO) radical scavenging activity. And we obtained results that Mori Ramulus was most effective with the concentration of 5 $mg/m{\ell}$, and Mori Cortex was most effective with the concentration of 2.5 $mg/m{\ell}$, And we examined the antioxidative effects of Mori Ramulus and Mori Cortex with $CU^{2+}/H_20_2$-induced Bovine serum albumin(BSA). And we obtained that antioxidative ability was increased after 1.25 $mg/m{\ell}$ and that was most effective with the concentration of 5 $mg/m{\ell}$ on both of them. And antioxidative ability of Mori Cortex was better than Mori Ramulus(p<0.05). So I guess that hot-water extracts of Mori Ramulus and Mori Cortex have effects on antioxidative ability, but Mori Cortex is better than Mori Ramulus on antioxidation. Hereafter we need differential experimental methods of antioxidative effect on both of them.

• The Korean Journal of Physiology and Pharmacology
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• 제22권3호
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• pp.235-248
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• 2018

Ursolic acid (UA) is a natural triterpene compound found in various fruits and vegetables. There is a growing interest in UA because of its beneficial effects, which include anti-inflammatory, anti-oxidant, anti-apoptotic, and anti-carcinogenic effects. It exerts these effects in various tissues and organs: by suppressing nuclear factor-kappa B signaling in cancer cells, improving insulin signaling in adipose tissues, reducing the expression of markers of cardiac damage in the heart, decreasing inflammation and increasing the level of anti-oxidants in the brain, reducing apoptotic signaling and the level of oxidants in the liver, and reducing atrophy and increasing the expression levels of adenosine monophosphate-activated protein kinase and irisin in skeletal muscles. Moreover, UA can be used as an alternative medicine for the treatment and prevention of cancer, obesity/diabetes, cardiovascular disease, brain disease, liver disease, and muscle wasting (sarcopenia). In this review, we have summarized recent data on the beneficial effects and possible uses of UA in health and disease managements.

• 한국정보통신학회:학술대회논문집
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• 한국정보통신학회 2017년도 추계학술대회
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• pp.602-604
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• 2017

인간의 수명이 늘어남에 따라 사람들은 건강하게 오래살고 싶은 욕구가 생기게 되었다. 특히 한국은 빠른 속도로 고령화 사회에 진입하였고, 고령화에 따른 질병의 증가로 의료비의 부담으로 이어졌다. 의료비 부담을 줄이기 위해 병의 치료보다는 예측과 예방이 중요하다. 개인의 유전자 정보를 측정하여 질병의 예측 및 예방을 할 수 있다. 개인의 유전자정보를 이용하기 위해서 한국인 질병과 표현형의 유전요인 발굴에 최적화된 SNP(80만개)과 GWAS를 통해 한국인의 유전정보를 파악하고 특정 집단의 유전적(체질적) 특성으로 각 개인의 유전자 정보를 분석한다. 본 논문은 특정 만성질환(비만, 당뇨 또는 심혈관계)집단을 분류할 수 있도록 분류 인덱스를 개발한다. 만성질환에 따른 맞춤식단 및 운동 관리를 위한 건강관리 서비스를 개발하고자한다.

• Journal of Nutrition and Health
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• 제52권6호
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• pp.593-603
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• 2019

Purpose: Previous studies have highlighted that the nutritional behaviors among South Korean workers are far from ideal. This study examined the organizational influences affecting the eating practices of office workers in South Korea. Methods: We conducted in-depth interviews with 22 office workers at 12 companies in South Korea. The interviewer inquired about the employees' daily routines on food and beverage intake. The various factors that influence their food choices in their work environments were also explored. The interviews were transcribed and then analyzed using a content analysis. Results: A framework analysis revealed 7 key recurring themes, and these were grouped under three levels: team-, company-, and corporate group-levels. First, team dinners are core social events for all the workers and they tend to include high-caloric food and alcoholic beverages. The frequency of team meals and the food associated with them depend on various team characteristics such as gender composition, the nature of a team's work and the team leaders' emphasis on group meals. Second, the company's policies and practices regarding budget allocation for team meals and subsidies for cafeteria meals affect the workers' food intake practices. In addition, the physical environment of the worksite cafeterias can influence the choices of foods. Third, various corporate group policies that were not designed to target food intake had additional positive effects on the workers' eating behaviors. Conclusion: This study provides important insights into the broader organizational influences on the food consumption of employees in their workplace. These insights can be used to design and implement more effective intervention strategies for improving the nutritional behaviors of office workers.

• Journal of Nutrition and Health
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• 제39권2호
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• pp.121-132
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• 2006

Minerals are extremely important in human metabolism, growth, and tissue repair. The risks of disturbances in mineral nutrition and metabolism are high following menopause. The aim of the study was to investigate the mineal nutrition status in middle-aged women (Pre & Postmenopausal) and the relation to climacteric symptoms. In the present study, we conducted the anthropometric measurement, climacteric symptoms survey and the dietary intakes including macronutrients, vitamins and minerals to assess the nutrient intakes. Also plasma mineral levels (Ca, P, Mg, Na, K, Fe, Cu, Zn) was measured. The participants were 105 middle-aged women (pre=51, Postmenopausal=54). The anthropometric measurement showed that 74% of subjects was overweight and obesity. The energy intakes were 83% of Korean EER. The macromineral intake (Ca, P, Mg, Na, K), Ca, P and Mg were 65%, > 116% and > 107% of Korean RI. Na and K intakes were > 243% and 53% of Korean AI. For the trace mineral intake (Fe, Cu, Zn), Fe, Cu and Zn intakes were 82%, > 146%, and 94% of Korean RI. The serum mineral concentration measurement, in case of Ca, Fe and Zn, > 10% of subjects showed lower level than normal clinical range. The most frequently appeared climacteric symptoms were dry eye, forgetfulness, difficult concentration, shoulder pain, fatique, depression & lonesomeness, backache, snore, dry skin, ankle & knee pain. In relation to mineral nutrition with climacteric symptoms, significant correlations have been founded between Ca intake and difficult concentration, Mg intake and snore, Fe & Zn intake and forgetfulness & dry skin, serum Ca concentration and forgetfulness, serum Na concentration and dry eyes & snore, serum K concentration and shoulder pain. From these results, it has been indicated that some mineral nutrition status may effect the prevention and reduction of climacteric symptoms in pre and postmenopause women.

• 한국학교보건학회지
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• 제20권1호
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• pp.77-90
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• 2007

Purpose : This study identified the patterns of smoking of students attending middle schools and high schools, and analyzed its related health risk behaviors. Methods: The data was based on the survey of 1,517 middle students and 911 high students residing in Kyung-Gi district. Results: The current smoking rates of male and female middle students are 5.3%, and 3.1% respectively. The rates of experiences in smoking are 21.4% and 16.0%(male/female). The current smoking rates of male and female high students are 17.9% and 8.5%, whereas the rates of experiences in smoking are 34.2% and 23.3% respectively. On the other hands, 14.1% of middle students and 12.0% of high students were exposed to smoking for at least 2 hours per day. The majority of middle and high school smokers started smoking when they were in middle or high school. And the most popular places to smoke were children's playgrounds, public open area., parks, and so on. Whether having a smoker as a friend or not and students' own perception towards smoking influenced the decisions to smoke for middle and high students. Both middle and high students, regardless of their gender, who have higher rates of drinking experiences and the hours of computer usage were found to have higher rates of smoking experiences. Meanwhile, the sleeping hours is in reverse proportion to the rate of smoking experiences. There was statistically significant difference in smoking experiences related to the degree of obesity only in the female high students: underweight and overweight students showed higher rates of smoking experiences than those falling in the normal weight range. Conclusion: For the effective prevention of adolescence smoking, it is necessary to adopt a comprehensive approach, which classifies the target population according to their age and sex and cover all health risk behaviors.

• 대한한방내과학회지
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• 제39권6호
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• pp.1181-1190
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• 2018

Objective: This study investigated the effect of purified medical herb extracts such as Alisma canaliculatum and Polyporus umbellatuson adipogenic differentiation of human bone marrow derived mesenchymal stromal stem cells (hBMSCs). Methods: Two different medical herb were extracted using hot distilled water. The optimal concentration of extracts were fixed at 100 ng/ml by means of cell viability and cytotoxic assay. To test the adipogenic differentiation ability of extracts, we induced the adipogenesis of hBMSCs for 21 days. At day 5, the cell was harvested to check mRNA and protein expression level of adipogenic related factors. The efficacy of lipid droplet formation was evaluated using the oil-red O staining method at days 21. Results: Two different medical herb extracts have no toxicity on hBMSCs. And two different medical herb extracts significantly decreased formation of lipid droplet compared with control groups in hBMSCs. The A. canaliculatum extract group showed the lowest mRNA and protein expression level of adipossgenic related transcription factors. This data suggests that extract of A. canaliculatum and P. umbellata decrease the adipogenic differentiation of hBMSCs. Conclusions: Our findings indicate that water-extract of A. canaliculatum and P. umbellata will be useful therapeutic reagents for prevention of obesity related disease such as diabetes, hyperlipidemia, coronary artery disease, and osteoporosis.

• 한국융합학회논문지
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• 제10권10호
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• pp.81-89
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• 2019

본 연구에서는 2013-2015년 국민건강영양조사 결과를 이용하여 우리나라 20-64세 성인 남녀 5,597명의 자료를 분석하였다. 현재 흡연자인 남성은 41.1%, 여성은 5.5%였으며, 현재 흡연자에서 대사증후군이 발생할 위험은 남성에서 연령 및 음주, 신체활동, 비만, 수면시간을 보정하였을 경우 1.785배 유의하게 증가하는 것으로 나타났지만, 여성에서는 유의하지 않았다. 흡연 및 대사증후군 유무에 따른 평균 영양소 섭취 차이를 분석 결과, 흡연자이면서 대사증후군이 있는 군에서 연령과 성별을 보정하였을 경우 에너지, 레티놀 및 비타민 C 섭취량에서만 유의한 결과를 보였다. 본 연구 결과 흡연 행태와 대사증후군 여부가 영양소 섭취와 연관이 있다는 것을 확인할 수 있었으며, 이에 따라 대사증후군의 예방과 관리를 위한 국가적인 수준의 생활습관 중재가 필요하겠다.

• 한국식품영양학회지
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• 제32권3호
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• pp.189-201
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• 2019

The objective of this study was to investigate the health status and nutritional intake of the old population living in Soonchang, Jeollabuk-do, Korea. 69 subjects aged 65 years and older were recruited in July 2016. The WHR, was significantly higher in elderly male group than elderly female group (p<0.05), but both groups had abdominal obesity (0.85 and over). T-score mean of elderly male and female groups were below $-2.5mg/cm^3$ that they were osteoporotic. In the elderly male group, the higher concentrations of creatinine, homocysteine and uric acid were found to be significantly unfavorable factors (p<0.001, respectively). The blood vitamin $D_3$ levels of elderly male group was significantly higher than that of elderly female group (p<0.05). The physical activity and self-rated health were significantly higher in elderly male group than in elderly female group (p<0.05, p<0.01, respectively). The nutrient intakes of male group were found to be significantly favorable factors than in female group. The score of mini nutrition assessment was significantly lower in elderly female group than in the elderly male group. These results could be useful to plan effective strategies to increase the health-life expectancy and the prevention of disease of Korean elderly people living in rural areas.

• 한국보건간호학회지
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• 제33권1호
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• pp.85-97
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• 2019

Purpose: The purpose of this study was to examine the mediating effect of physical activity, dietary habit, and academic stress, as well as the moderating effect of gender on the relationship between adolescents' quality of sleep and body mass index (BMI). Methods: The data were collected from 181 adolescents and analyzed using SPSS WIN 23.0. Bootstrapping analysis was performed to analyze the mediating and moderating effects. Results: First, there was non-significant mediating effect between the quality of sleep and BMI. Second, there was significant moderating effect between the quality of sleep and BMI. Conclusion: Sleep quality should be considered as a component of an intervention program for the prevention and management of obesity. It is also necessary to consider then gender when constructing such program.