• 제목/요약/키워드: Obesity Stress

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In Search for a Common Pathway for Health Issues in Men - the Sign of a Holmesian Deduction

  • Aoun, Fouad;Chemaly, Anthony Kallas;Albisinni, Simone;Zanaty, Marc;Roumeguere, Thierry
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.1
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    • pp.1-13
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    • 2016
  • The evidence for the existence of a common pathway for health issues in men is presented in this review. Several epidemiological studies have shown that conditions like cardiovascular diseases (CVD), metabolic syndrome, diabetes, lower urinary tract symptom (LUTS), erectile dysfunction (ED), prostate cancer, hypogonadism, depression and suicide can be associated as risk factors for each other. Thus, the risk of CVD is significantly increased in men with metabolic syndrome, ED, hypogonadism, prostate cancer and/or LUTS. In addition, the above mentioned conditions are more prevalent in atherosclerotic patients. In addition, growing evidence indicates that low androgen levels can cause metabolic syndrome. In addition, obesity, dyslipidaemia and diabetes can further reduce androgen levels potentiating their adverse effect. Low testosterone levels are also associated with a higher incidence of aggressive prostate cancer on biopsy and on definitive pathology, and lower probability of abiraterone response in the metastatic setting. Several recent studies point towards diffuse endothelial dysfunction and dysregulated pro-inflammatory state as the biological link between all these disorders. Our current hypothesis is that oxidative stress caused by these dysfunctions explains the pathogenesis of each of these conditions.

Oral Administration of a Hot Water Extract of the Softshell Turtle (Trionyx sinensis) Improves Exercise Performance

  • Harwanto, Dicky;Lee, Gong-Hyeon;Park, Sun-Mee;Choi, Jae-Suk;Kim, Mi-Ryung;Hong, Yong-Ki
    • Preventive Nutrition and Food Science
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    • v.20 no.2
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    • pp.133-136
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    • 2015
  • Freshwater softshell turtle (Trionyx sinensis) extract has been used traditionally as a tonic soup, and to recover from physical fatigue. To support these claims, the forelimb grip strength of mice was measured after feeding a soft-shell turtle extract for 7 days. The T. sinensis extract significantly increased the grip strength to $1.25{\pm}0.07N$ (P<0.01), which is 16.8% higher than the force on day 0. After exercising, the blood glucose levels in extract-fed mice were 202% higher and urea levels were 73% lower, which were both significantly different than the levels observed after control treatment. Lactate dehydrogenase was significantly higher by 314%, and glutathione peroxidase increased by 165%. In addition, the obesity markers, serum triglyceride and cholesterol, decreased to 62% and 49%, respectively, after mice were fed the extract. These data show that the T. sinensis extract provided more energy for forelimb exercise, prevented protein catabolism and muscle fatigue, and decreased the oxidative stress caused by an exhaustive workout.

Cardiovascular Disease in Pediatric Chronic Kidney Disease (소아 만성 콩팥병에서 나타나는 심혈관계 질환)

  • Cho, Min Hyun
    • Childhood Kidney Diseases
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    • v.18 no.1
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    • pp.7-12
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    • 2014
  • Cardiovascular disease (CVD) has been identified as one of the most important factors influencing the long-term prognosis of patients with chronic kidney disease (CKD). However, in pediatric CKD, the clinical importance of CVD tends to be overlooked due to the lack of typical manifestations of CVD in this population. The literature has identified several traditional risk factors of CVD that originate from CKD, including hypertension, diabetes mellitus, dyslipidemia and obesity, in addition to new and non-traditional risk factors including anemia, secondary hyperparathyroidism, oxidative stress and inflammation. In cases of pediatric CKD, cardiovascular disease is usually restricted to subclinical manifestations such as left ventricular hypertrophy, thickening of intimal media on the carotid artery and calcification of the coronary artery. Therefore, risk factors of CVD in pediatric CKD patients should be closely monitored.

The Health and Nutritional Status of Urban Area Workers in Korea (도시 직장인의 건강 및 영양 상태 조사 (I))

  • Kim, Yeong-Ju;Jo, Yeo-Won;Hong, Ju-Yeong
    • Journal of the Korean Dietetic Association
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    • v.5 no.2
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    • pp.128-136
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    • 1999
  • This study was conducted to evaluate the workers' health conditions, nutritional status, food habits, and their needs for the nutrition programs at the worksite. Three hundred and fifty one(men 260, women 91) employees from 11 companies in urban area were recruited for the study. The results of this study were as follows : The average consumption of nutrients in the subjects' diets were found to be deficient such as total energy, calcium, iron, vitamin A and $B_2$. More than 42% of the subjects have at least one of the chronic diseases like obesity, diabetes mellitus, anemia, hypercholesterolemia, liver disease, and hypertension. Most subjects did not recognize their own blood cholesterol levels, blood pressure, or blood sugar level. Nutrition knowledge scores of the subjects were very low, which was only 52.4%. It should be noted that weight problems and other health problems of the employees at the worksite were frequently found among the employees who had relatively low nutrition knowledge scores. The nutrition programs for prevention of the obeses, hypercholesterolemia, diabetes mellitus, stress, and smoking were urgently needed by the subjects. Many subjects also wanted the nutrition education programs for their family.

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A Study on Body Image Perception and Eating Disorders by Gender in Junior high school students Seoul (서울 일부지역 청소년들의 성별에 따른 체형인식 및 식이장애 실태 비교)

  • Kim, Jung-Hyun;Jung, In-Kyung
    • Journal of the Korean Home Economics Association
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    • v.45 no.1
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    • pp.101-109
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    • 2007
  • This study was performed to investigate body image perception and eating disorders by sex in Korean adolescents. In both females and males, the students were more likely to be underweight than overweight. Females were more underweight than males and were more likely to perceive themselves as overweight. In addition, females were less satisfied with their body shape and had more stress associated with their body weight and eating disorders. These results indicate that nutrition education programs, particularly in female students, should incorporate strategies to change inaccurate self-body image perception and disseminate knowledge about proper weight control methods.

Water Extract of Ash Tree (Fraxinus rhynchophylla) Leaves Protects against Paracetamol-Induced Oxidative Damages in Mice

  • Jeon, Jeong-Ryae
    • Food Science and Biotechnology
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    • v.15 no.4
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    • pp.612-616
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    • 2006
  • The protective effect of water extract of ash tree leaves (ALE) against oxidative damages was investigated in paracetamol-induced BALB/c mice. Biochemical analysis of anti-oxidative enzymes, immunoblot analyses of hepatic cytochrome P450 2El (CYP2E1), and the gene expression of tumor necrosis factor (TNF-${\alpha}$) were examined to determine the extract's protective effect and its possible mechanisms. BALB/c mice were divided into three groups: normal, paracetamol-administered, and ALE-pretreated groups. A single dose of paracetamol led to a marked increase in lipid peroxidation as measured by malondialdehyde (MDA). This was associated with a significant reduction in the hepatic antioxidant system, e.g., glutathione (GSH). Paracetamol administration also significantly elevated the expression of CYP2E1, according to immunoblot analysis, and of TNF-${\alpha}$ mRNA in liver. However, ALE pretreatment prior to the administration of paracetamol significantly decreased hepatic MDA levels. ALE restored hepatic glutathione and catalase levels and suppressed the expression of CYP2E1 and TNF-${\alpha}$ observed in inflammatory tissues. Moreover, ALE restored mitochondrial ATP content depleted by the drug administration. These results show that the extract of ash tree leaves protects against paracetamol-induced oxidative damages by blocking oxidative stress and CYP2E1-mediated paracetamol bioactivation.

Factors Associated with Chronic Disease Occurrence in One-person Household Depending on Gender (성별에 따른 1인 가구 성인의 만성질환 유병 관련 요인)

  • Lee, Eun Sook
    • Journal of East-West Nursing Research
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    • v.27 no.2
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    • pp.166-176
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    • 2021
  • Purpose: This study was conducted to assess the effect of household types on the occurrence of chronic diseases depending on gender and to identify the factors associated with chronic disease occurrence in one-person households. Methods: Multivariate logistic regression analysis was conducted using the data of 15,949 adults with the age of 19 years or older from the sixth Korea National Health and Nutrition Examination Survey (2013~2015). Results: For male, the risk of chronic disease occurrence was higher in one-person households than in multi-person households, and the same held true after adjusting for the confounding factors. For female, no significant relationship was found between household types and chronic disease occurrence. Factors associated with chronic disease occurrence were age, employment state, marital state, smoking, perceived stress, and depression in male, and age, employment state, physical activity, and obesity in female. Conclusion: It is necessary to monitor the disparity in health depending on household types in male. Additionally, providing a gender specific chronic disease prevention and health enhancement program is required.

The Chronic Health Effects of Work-Related Stressors Experienced by Police Communications Workers

  • Perez, Rodolfo A.;Jetelina, Katelyn K.;Reingle Gonzalez, Jennifer M.
    • Safety and Health at Work
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    • v.12 no.3
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    • pp.365-369
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    • 2021
  • Background: Law enforcement communications (i.e., 911 dispatch and call takers) is a challenging and stressful occupation. The purpose of this study is to identify the main stressors associated with employment in law enforcement communications, and to identify and provide context to how these stressors affect workers' health and wellbeing. Methods: This research study included focus groups with 23 call takers and 911 dispatchers employed by a large, urban law enforcement agency in 2018. Thematic analyses were conducted to identify trends. Results: Four themes of stressors emerged (i.e., the high stakes nature of some 911 calls for service, understaffing, supervisor-related stress, and recruiting practice). Two health-related themes emerged as being occupation-related: weight gain and poor sleep patterns/insufficient sleep). Specifically, participants reported negative eating habits resulting in weight gain and obesity, lack of sleep and irregular sleep schedules, and development of hypertension and/or diabetes since beginning their jobs. Conclusion: Law enforcement communications professionals experience a number of the same stressors facing law enforcement officers in patrol. These stressors, combined with the sedentary nature of the job, could result in long-term, chronic health problems.

Pharmacological Viewpoint Concerns and Phytochemical Components of Ginseng

  • RANA, Anvi
    • The Korean Journal of Food & Health Convergence
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    • v.8 no.5
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    • pp.21-28
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    • 2022
  • Ginseng is described as the "King of all herbs, "Man-root" or "Root of heaven" and regarded as the most powerful herbal remedy, particularly grown in Korea, China, Japan, Vietnam, and North America. It has been in existence for a long time. The most demanded herbal cure, Ginseng, principally the root, has long been employed in traditional Asian medicine. The extent of availability of bioactive combinations and their impact on the body differs between American and Asian ginseng. Asian ginseng, also known as Panax ginseng, has a more calming influence and is more advantageous than American ginseng, such as Panax quinquefolius. The pharmaceutical aspect of development and extraction with diverse morphological properties is examined. Saponins, glycosides, carbohydrates, polyacetylenes, amino acids, vitamins, volatile oil, enzymes are all present in the Phyto-content of Ginseng. Ginsenosides are saponins that are constituents of the triterpenoid dammarane and have anticancer, anti-cardiovascular, anti-microbial, anti-obesity, anti-inflammatory, and antioxidant properties. Ginseng, in particular, has the possibility to help with microbial invasion, inflammatory processes, oxidative stress, and diabetes. It developed nanoparticles and nanocomposite film technologies as novel drug delivery platforms for cancer, inflammation, and neurological illnesses. Furthermore, it offers a range of applications that will be vital for future growth.

Factors affecting unmet healthcare needs of low-income overweight and obese women in Korea: analysis of the Korean National Health and Nutrition Examination Survey 2017

  • Nho, Ju-Hee;Park, Sook Kyoung
    • Women's Health Nursing
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    • v.27 no.2
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    • pp.93-103
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    • 2021
  • Purpose: The purpose of this study was to explore unmet healthcare needs among low-income overweight and obese women and to identify the factors affecting unmet healthcare needs. Methods: The study was a secondary analysis of data from the 2017 Korea National Health and Nutrition Examination Survey. A final sample of 388 out of 8,127 participants was analyzed using complex descriptive statistics, the chi-square test, the independent t-test, and logistic regression. Results: The mean age of the participants was 66.51±1.05 years. Unmet healthcare needs were experienced by 19.4% of low-income overweight and obese women. Women with depression, stress, and poor self-reported health status were significantly more likely than their counterparts to experience unmet healthcare needs. Poor self-reported health status was confirmed to be related to unmet health needs in low-income overweight and obese women (odds ratio, 2.65; p=.011). Conclusion: The study provides the novel insight that the unmet healthcare needs of low-income overweight and obese women were influenced by self-reported health status. Healthcare providers should make efforts to develop strategies to reduce unmet healthcare needs among low-income overweight and obese women, who constitute a vulnerable population.