Purpose: We performed to reveal the association between the Helicobacter pylori infection and body weight among children. Methods: Out retrospective study included patients who underwent the H. pylori immunoglobulin G testing at Konyang University Hospital between March 2011 and June 2014. These patients were classified as seropositive (28 boys, 27 girls; mean age: $9.89{\pm}3.28years$) or seronegative (55 boys, 54 girls; mean age: $9.84{\pm}3.02years$). Next, we compared various characteristics between the seropositive and negative groups, as well as between obese children (body weight ${\geq}90th$ percentile) and non-obese children (body weight <90th percentile). Furthermore, we compared the change in body weight after 2 months of treatment with amoxicillin, clarithromycin and omeprazole among the 55 seropositive children (14 treated children and 41 non-treated children). Results: There were no differences in the weights and laboratory data for the 55 seropositive children and 109 seronegative children (weight; $40.96{\pm}18.11kg$ vs. $36.85{\pm}13.72kg$, respectively; p=0.14). And, there was no difference in the prevalence of H. pylori infection among the 29 obese and 135 non-obese children (p=0.581). However, after 2 months of eradication, the 14 treated patients exhibited a significant weight gain ($+0.91{\pm}0.52kg$), compared to the 41 non-treated patients ($-0.29{\pm}1.16kg$, p=0.025). Conclusion: Our findings present that obesity was not associated with the H. pylori infection, although H. pylori eradication led to significant increase in body weight.
The purpose of this study was to investigate the dietary related factors and blood parameters of moderately or severely obese children residing in Samcheok. Anthropometric measurement, 24-hour recall for dietary intake, blood analysis and questionnaire response including nutritional knowledge, nutritional attitude, body image recognition and eating habits were conducted in 23 obese children(16 boys and 7 girls) and their mother. The mean age of subjects are 10.0 years. The average body weight, BMI, obesity index and percent body fat were 57.5㎏, 27.0㎏/$m^2$, 47.3 and 38.1% in boys and 51.0㎏, 24.8㎏/$m^2$, 40.3 and 43.9% in girls. The average nutritional attitude, the self-satisfaction and the nutritional knowledge scores in subjects were 29.9/40, 32.7/50 and 7.3/10, respectively. 34.8% of the subjects were unsatisfied with their body image, whereas, 81.8% of their mothers were unsatisfied with children’s body image. 60.9% of subjects had one or both obese parents. Average intake of energy were 90.6% of RDA in boys and 84.3% of RDA in girls. The ratio of energy from carbohydrate/protein/fat were 66/16/18 in boys and 66/17/17 in girls. The mean serum cholesterol concentration of the subjects was 191.8mg/dl and 78.3% of the subjects were above the normal serum cholesterol rage of children. In the results of correlation analysis, obesity index was negatively correlated with self and mother’s nutritional attitude scores. Body weight and BMI were positively correlated with vitamin C(p<0.05) and fruits(p<0.05) intakes. And there was a positive correlation between obesity index and BMI, and serum cholesterol(p<0.05).
Purpose: This study aimed to investigate the clinical and metabolic determinants of circulating soluble leptin receptor (CSLR) and free leptin index (FLI) in pre-pubertal obese male children. Methods: We conducted a preliminary cross-sectional study at three tertiary hospitals and one public primary school. Eighty obese male children without growth and developmental abnormalities aged 5-9 years were recruited. In these children, obesity was solely caused by excessive food intake, and not by acute illness, medications, endocrine abnormalities, or any syndrome. Body mass index (BMI), body fat mass, carbohydrate intake, fat intake, high density lipoprotein cholesterol level, low density lipoprotein cholesterol level, triglyceride level, and Homeostatic Model Assessment for Insulin Resistance are the potential determinants for leptin regulation, which is represented by CSLR level and FLI. Results: Carbohydrate was the main source of energy. BMI and body fat mass had negative weak correlation with CSLR and positive weak correlation with FLI. Furthermore, carbohydrate intake was found to be independently associated with CSLR based on the results of the multiple linear regression analysis. Following an increase in carbohydrate intake, CSLR level decreased progressively without any negative peak. Conclusion: Leptin regulation in prepubertal obese male children is associated with body composition and dietary intake. Carbohydrate intake is useful for predicting CSLR. Lipid profiles and insulin resistance are not related to both CSLR and FLI. Treatment and prevention of leptin resistance in obese children should focus on reducing BMI, fat mass, and carbohydrate intake.
This study was conducted to develop a comprehensive program for improving obese children's living habits such as wearing clothing and eating, and their self-esteem. Thirteen obese elementary school children, six boys and seven girls in the 4th to 6th grade, voluntarily participated in a ten-week intervention program. During the program, the obese children filled out a checklist consisted of daily ambient temperature inside the house, weight of clothing, meal diary, time taken for physical exercise, time taken for watching TV, etc. After carrying out the program, its effect was testified and evaluated. Percent body fat of the children measured using a body composition analyzer was reduced by $1.9\%$ after the program (p<.01). Wearing behavior of clothing was positively changed in view of the high correlation between ambient temperature and clothing weight (r=-.917, p<.01). Ability of dietary self control was improved and eating time was lengthened. Self-esteem was improved in global self-worth, athletic competence, and behavior/conduct. It was suggested that active interest of the family would be helpful and that an intervention program over longer than ten week would be necessary to improve childhood obesity.
The aim of this study is to suggest the effective protocol to manage the obese children using the data based on PAPS(Physical Activity Promotion System). In the school, there are a lot of efforts for the management of increasing obese children through the data obtained from PAPS which is conducted annually includes the assessment of obesity. But the follow-up of obese children was not effective due to the workload of teachers and the lack of available manpower. For more active and systematic management, the combination of a smart device transfer in the existing ways for facilitating access to the information is more effective. The information of obese children such as fitness, health, and obesity automatically will be sent in web-PAPS, And when personalized exercise prescription, proper nutrition education for obesity are shared with their parent, it will be more effective in weight management.
Purpose: This study was performed to evaluate the quality of sleep in snoring obese children without obstructive sleep apnea (OSA); and to study the possible relationship between sleep interruption and gastroesophageal reflux (GER) in snoring obese children. Methods: Study subjects included 13 snoring obese children who were referred to our sleep lab for possible sleep-disordered breathing. Patients underwent multichannel intraluminal impedance and esophageal pH monitoring with simultaneous polysomnography. Exclusion criteria included history of fundoplication, cystic fibrosis, and infants under the age of 2 years. Significant association between arousals and awakenings with previous reflux were defined by symptom-association probability using 2-minute intervals. Results: Sleep efficiency ranged from 67-97% (median 81%). A total of 111 reflux episodes (90% acidic) were detected during sleep, but there were more episodes per hour during awake periods after sleep onset than during sleep (median 2.3 vs. 0.6, p=0.04). There were 279 total awakenings during the sleep study; 56 (20.1%) of them in 9 patients (69.2%) were preceded by reflux episodes (55 acid, 1 non-acid). In 5 patients (38.5%), awakenings were significantly associated with reflux. Conclusion: The data suggest that acid GER causes sleep interruptions in obese children who have symptoms of snoring or restless sleep and without evidence of OSA.
Background: Obesity is a complex, medical condition causally contributing to many chronic diseases and a number of efforts have been made to find the associated markers for novel prevention and treatment of obesity. Our study was to evaluate the relationship between gut immune response and obesity and overweight with use of fecal calprotectin (FC) both in adult and children groups. Methods: Fecal samples were obtained from 74 subjects: 14 non-obese and overweight children (PN), 13 obese and overweight children (PO), 20 non-obese and overweight adults (AN), and 27 obese and overweight adults (AO). FC was measured using a commercial Legend Max quantitative enzyme-linked immunosorbent assay (BioLegend). Mann-Whitney U-test was used for statistical analysis. Results: Median FC concentration was $7.9{\mu}g/g$ (range, $1.9-28.9{\mu}g/g$) for PN, $5.0{\mu}g/g$ (range, $2.6-29.6{\mu}g/g$) for PO, $9.5{\mu}g/g$ (range, $0.8-28.9{\mu}g/g$) for AN, and $10.0{\mu}g/g$ (range, $1.6-25.6{\mu}g/g$) for AO, respectively. In both adults and children age groups, the FC showed no statistically significant difference between AO and AN or PO and PN. However, FC showed statistically significant difference (P<0.05) between AO and PO while not significant between AN and PN. Conclusion: FC level in AO was significantly higher than that in PO, suggestive of different pathophysiologic mechanism between children obesity and adults obesity.
This study was conducted to investigate the change in the anthropometric values, biochemical index, nutritional knowledge, food habits and nutrient intakes in obese children after a weight control program. The subjects of the study were 22 obese children with an obesity index over 120%. The children that participated in this study took nutritional education for weight control along with exercise once a week. The weight control program was conducted for 10 weeks. The BMI, WHR (Waist-Hip ratio), body fat (%) significantly decreased at the end of the weight control program. Total cholesterol and LDL cholesterol were also significantly decreased. The nutritional knowledge scores and knowledge score about obesity were slightly improved. Energy intake significantly decreased from 1768 to 1421 kcal. Intake of Ca, Na, K, vitamin A, vitamin $B_6$, vitamin C and folate increased, while intakes of P, Zn, vitamin $B_1$, vitamin $B_2$, vitamin E and niacin decreased. The distribution of energy intake was significantly changed for the better. The percent fat consumed decreased from 26.5 to 19.7%. In addition, the distribution of energy intake in the meals was changed, where the percent calories consumed during lunch significantly increased from 31.4 to 40.1% and the calorie percentage consumed from snacks significantly decreased from 17.6 to 10.7%. In conclusion, the nutritional education in the weight control program, which was conducted for 10 weeks, was effective in improving the anthropometric values, biochemical index and nutrient intake although nutrition knowledge and eating behaviors only changed slightly. Thus, nutritional weight control programs for obese children should be continuously provided under the proper cooperation of a nutritional teacher at elementary schools.
For the purpose of ascertaining the status of physical growth and food habit of obese children, a study was made of 1086 primary school children ranging between 2nd and 3ra grades living in Kwang-ju City in Korea. 66 subjects were selected from an anthropometrical point of view and they were classified into two groups, an obese group and a control group, according to their relative body weight. Food habits of each group were observed by means of questionnaires. In the statistical analysis of the data, percentage calculation and T-score test were used. The results of the study can be summarized as follows; 1) Viewed from relative body weight, 3.0% of the 1,086 subjects turned out to be obese, and the measure of skinfold showed 2.4%. 2) Physical growth of the obese growth is superior to that of the control group in all aspects. 3) The average score of food preference by means of Hedonic scaling method by the obese group is 3.90, while that of food preference by the control group is 3.76. The most favored food by the obese group is ice cream (4.91), while that of most favored food by the control group is banana (4.75). The statistically meaningful foods of the two groups are cucumber (0.02>p>0.01), orange (p<0.02), peach(0.05>p>0.02), watermelon (p <0.01) and ice cream (p<0.01). The score of food preference for protein foods by the obese group is 3.78 and that of food preference by the control group is 3.57(0.05>p>0.02). The excessive food intake per meal of the obese group is 45.4%, while that of the control group is 19.7% (0.05>p>0.02). Ratio of taking severely unbalanced food by the obese group is 15.1%, while that of the control group is 50.0% (p<0.01). 4) 30.3% of mothers of the obese group is fat, while 15.1% of mothers of the control group is fat (p<0.01). Concerning body weight at birth, 90.9% of the obese group and 63.6% of the control group are above-average weight. (p <0.01). From the results shown above, the obesity in children is almost due to food. It is hoped, therefore, that overeating be discouraged through the nutrition education.
The purpose of this study was to investigate the effects of parent's nutritional education for body weight control of obese children. The weight control program include nutritional education, exercise and behavioral therapy during 20 weeks. Twenty- three children completed this program, the children were divided into two groups by control group and parent's nutritional education group. Parents volunteered to participate in a 4 week nutritional education program for parents and contact the therapist at least once per week to help their obese children. The results from this study were as follows. There were not significant differences in anthropometric values after weight control program between two groups. Triglyceride(TG) level in serum was decreased after weight control program in group of parent's nutritional education, but there was not significant difference. Parent's nutritional education did not add improvements in weight and fitness, but the children of parent's nutritional education group showed increased general self-worth upon completing the program(p<0.05) whereas the other children of control group did not. Also there were desirable changes of exercise and life habits in group of parent's nutritional education group.
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