• 제목/요약/키워드: OTF

검색결과 108건 처리시간 0.024초

Rhodium(III)-mediated cycloaddition reactions of alkynes

  • 한원석;이순원
    • 한국결정학회:학술대회논문집
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    • 한국결정학회 2002년도 정기총회 및 추계학술연구발표회
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    • pp.30-30
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    • 2002

  • Heating [Cp＊Rh(η²-NO₃)(OTf) (1) and PhC≡CPh in EtOH for 3 h gave a η⁴-cyclobutadienerhodium complex, [Cp＊Rh(η⁴-C₄Ph₄)] (2). Complex 1 reacted with HC=CPh in acetone at room temperature for 3 h to give a (η⁴-cyclobutadiene)-rhodium complex, [Cp＊Rh(η⁴-C₄HPhC=CPh)] (3). Whereas, the reactions of 1 with HC=CCH₂Cl in acetone at room temperature for 3 h gave the triply halide-bridged dinuclear rhodium complex, [Cp＊Rh(μ₂-Cl)₃RhCp＊](OTf) (4). Complexes 2-4 have been structurally characterized by X-ray diffraction.

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2-(1,3,3-Trimethyl-6-azabicyclo[3,2,1]-oct-6-yl)-4,5-dihydro-1,3-oxazoline(TAO)의 개환이성화중합과 특성평가 (Characteristics and Ring-Opening Isomerization Polymerization of 2-(1,3,3-Trimethyl-6-azabicyclo[3,2,1]-oct-6-yl)-4,5-dihydro-1,3-oxazoline (TAO))

  • 이찬우;정진도
    • 폴리머
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    • 제36권3호
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    • pp.262-267
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    • 2012

  • 할로겐화알킬($PhCH_2Br$, $PhCH_2Cl$, MeI)과 설폰산에스테르(MeOTf)를 개시제로 사용하여 $100^{\circ}C$, 24시간의 반응조건으로 2-(1,3,3-trimethyl-6-azabicyclo[3,2,1]-oct-6-yl)-4,5-dihydro-1,3-oxazoline(TAO)의 중합을 실시, 개시제에 의한 폴리머구조의 영향을 관찰한 결과, 양쪽 개시제 모두 거의 동일한 연쇄이동에서 나타나는 경향과 비슷한 결과를 얻었다. 그러나 개시제에 의한 폴리머의 구조는 설폰산에스테르계 개시제에서는 거의 100% pendant type 폴리머가 생성되는 반면, 할로겐화알킬계 개시제를 사용한 TAO중합은 pendant type 단위와 main chain type의 단위가 소량 생성됨이 확인되어 이것은 구핵성이 높은 할로겐 음이온에 의한 이중이성화중합이 부분적으로 진행되었음을 확인하였으며, 개시제로 Merrifield수지를 사용한 TAO와의 공중합에서는 다량의 단일중합체가 부생되는 그래프트 공중합체가 생성되었다.

  • https://doi.org/10.7317/pk.2012.36.3.262 인용 PDF KSCI

APPLICATIONS OF SELF-REFERENCING METHOD TO THE VIRGO CLUSTER SPIRALS

  • Chung, Eun-Jung;Kim, Hyo-Young;Rhee, Myung-Hyun
    • 천문학회지
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    • 제38권4호
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    • pp.371-384
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    • 2005

  • Self-referencing method in revised-OTFTOOL is a new method in On-The-Fly(OTF) observation mode. It uses the source free regions of the observed frame as references instead of the OFFs references. We already analyzed and discussed its proprieties and advantages in the previous paper. In this paper, we make a statistical study about the self-referencing method by applying it to OTF mapping data of 27 Virgo spiral galaxies. We found that the self-referencing method solves the crooked baseline problem for every datacube. It straightens the baseline, and conserves the emissions. Compared with other data processing, the median filtering task 'mwflt' in AIPS, to use self-referencing method is more effective and safe not only to straighten the baseline but also to conserve the emission. For the strong CO galaxies, the data obtained by self-referencing method shows scarcely any difference from those reduced by conventional OFFs references and AIPS median filtering in the range of uncertainties. Undetected CO emissions in datacubes of conventional OFFs references are also not detected in those of self-referencing method. The self-referencing method is expected to save the observing time and simplify data reduction processes. Besides this, using self-referencing method will offer emission-free references more safely.

  • https://doi.org/10.5303/JKAS.2005.38.4.371 인용 PDF KSCI

Radiolabeling of 11C-sertraline by fast and easy loop method with [11C]CH3OTf

  • Lee, Hak Jeong;Jeong, Jae Min;Lee, Sang-Yoon;Ido, Tatsuo
    • 대한방사성의약품학회지
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    • 제3권1호
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    • pp.32-37
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    • 2017

  • Cis-(1S,4S)-4-(3,4-dichlorophenyl)-1,2,3,4-tertrahydro-N-methyl-1-naphthalenamine (sertraline) hydrochloride from among selective serotonin reuptake inhibitors (SSRIs) is a treatment of major depression. For the differential diagnosis by metabolizing serotonin in a patient with neurological disorders, the radiolabeled $^{11}C$-sertraline was developed for non-invasive positron emission tomography in living brain and use the evaluation of new drug for SSRIs. We release the results of a fast and easy radiolabeling method applied a one-step loop method with $[^{11}C]CH_3OTf$ for routine clinical applications of $^{11}C$-sertraline. 1 mg of a precursor for $^{11}C$-sertraline in 0.1 mL DMF and $5{\mu}L$ of 1N NaOH, were injected into the loop of semi-prep high-performance liquid chromatography (HPLC). $[^{11}C]CH_3OTf$ was passed through the loop at room temperature (RT). The $^{11}C$-sertraline was separated by the semi-preparative HPLC. $^{11}C$-sertraline was eluted at 28.0 min was collected and evaluated by analytical HPLC and mass spectrometer. The total radiolabeling efficiency of $^{11}C$-sertraline was $30.7{\pm}8.7%$. The specific activity was $64.8{\pm}51.4GBq/{\mu}mol$. The radiochemical and chemical purities were higher than 99%. The mass spectrum of the product showed m/z peaks at 307.1 (M+1), indicating the mass of sertraline. By the one-step loop method with $[^{11}C]CH_3OTf$, $^{11}C$-sertraline could be quickly and easily prepared for clinical application.

  • https://doi.org/10.22643/JRMP.2017.3.1.32 인용 PDF KSCI